Machine learning (ML) algorithms present an opportunity to estimate joint kinetics using a limited set of mechanical sensors. These estimates could be used as a continuous reference signal for exoskeleton control, able to modulate exoskeleton assistance in real-world environments. In this study, sagittal plane biological hip torque during level ground, incline and decline walking was calculated using inverse dynamics of human subject data. Subsequently, this torque was estimated using neural network (NN) and XGBoost ML models. Model inputs consisted solely of mechanical sensor data onboard a robotic hip exoskeleton. These results were compared to a baseline method of estimating hip torque as the mean torque profile during ambulation. On average across conditions, the NN and XGBoost models estimated biological hip torque with an RMSE of 0.116±0.015 and 0.108±0.011 Nm/kg, respectively, which was significantly less than the baseline estimation that had an RMSE of 0.300±0.145 Nm/kg (p<0.05). Fitting the baseline method to ambulation mode specific data significantly reduced overall RMSE by 59.3%; however, the ML models were still significantly better than the baseline method (p<0.05). These results show that machine learning algorithms can estimate biological hip torque using only mechanical sensors onboard a hip exoskeleton better than simply using an average torque profile. This suggests that these estimation models could be suitable for modulating exoskeleton assistance. Additionally, no evidence suggested the need to train separate ML models for each ambulation mode as estimation RMSE was not significantly different across unified and separated ML models.