The joint is the connection part of a hollow-core slab bridge. Thus, it is necessary to study the joint systematically. In this paper, 15 beams with the joint were designed to study the mechanical behavior and the load transfer mechanism of the joints under flexure load, shear load, and flexure-shear load, and the corresponding failure mode was observed. The effects of pavement layer thickness, concrete surface treatment, joint concrete strength, and joint form on the mechanical properties of joints were studied. And the strengthening effects of CFRP strengthening technology and locally prestressed tendons strengthening technology were studied. The test results showed that the failure mode of all specimens was cracking at the interface between the joint and the beam segment. Cracks started from the bottom of the specimen and extended upward with the increase of load. The mechanical behavior of joints could be improved by increasing the pavement layer thickness, interface roughness, joint width, and the number of tensile rebars. However, the concrete strength of the joint had little effect on the mechanical behavior. CFRP could effectively delay crack development and improve mechanical behavior. The specimen with a locally prestressed tendon performed better structural integrity than the control specimen. Furthermore, according to the results obtained from the AASHTO and experiments, a factor with the aim to correct the calculated values of the bearing capacity in the code was proposed.