Skinfold Thickness Measurements Research Articles

Triceps skinfold thickness trajectories and the risk of all-cause mortality: A prospective cohort study.

The measurement of triceps skinfold (TSF) thickness serves as a noninvasive metric for evaluating subcutaneous fat distribution. Despite its clinical utility, the TSF thickness trajectories and their correlation with overall mortality have not been thoroughly investigated. To explore TSF thickness trajectories of Chinese adults and to examine their associations with all-cause mortality. This study encompassed a cohort of 14747 adults sourced from the China Health and Nutrition Survey. Latent class trajectory modeling was employed to identify distinct trajectories of TSF thickness. Subjects were classified into subgroups reflective of their respective TSF thickness trajectory. We utilized multivariate Cox regression analyses and mediation examinations to explore the link between TSF thickness trajectory and overall mortality, including contributory factors. Upon adjustment for multiple confounding factors, we discerned that males in the 'Class 2: Thin-stable' and 'Class 3: Thin-moderate' TSF thickness trajectories exhibited a markedly reduced risk of mortality from all causes in comparison to the 'Class 1: Extremely thin' subgroup. In the mediation analyses, the Geriatric Nutritional Risk Index was found to be a partial intermediary in the relationship between TSF thickness trajectories and mortality. For females, a lower TSF thickness pattern was significantly predictive of elevated all-cause mortality risk exclusively within the non-elderly cohort. In males and non-elderly females, lower TSF thickness trajectories are significantly predictive of heightened mortality risk, independent of single-point TSF thickness, body mass index, and waist circumference.

Associations of prenatal exposure to bisphenols with infant anthropometry: A prospective cohort study

BackgroundBisphenols (BPs) have been shown to exhibit developmental toxicities. Epidemiological evidence on prenatal BPs exposure and infant growth primarily confined scopes to specific BPs and birth outcomes, with few studies focusing on infant growth and reporting inconsistent findings. The joint effect of prenatal exposure to BPs mixture on infant growth was rarely studied. ObjectiveThis study examined associations of prenatal exposure to individual bisphenol A (BPA) and its analogues (bisphenol F [BPF], bisphenol S [BPS], bisphenol AF [BPAF], and tetrachlorobisphenol A [TCBPA]) and their mixture with infant growth. MethodsUrinary concentrations of BPs in pregnant women were quantified. Weight, body mass index, skinfold thickness, and circumference measurements of infants were collected at birth, 6 and 12 months of age, rapid growth and overweight were further defined. Multiple linear regression models and Bayesian kernel machine regression models (BKMR) were used to analyze associations of exposure to individual BPs and BPs mixture with infants' anthropometric measurements, and to identify the important components among mixture. The risks for rapid growth and overweight of each BP were determined using modified Poisson regression models. ResultsA general profile of higher prenatal BPs exposure (mainly BPA, BPF, and BPS) associated with higher anthropometric measurements and higher risks of overweight during infancy was found. We also observed higher risks of rapid growth in infants following prenatal BPs exposure, with risk ratios ranging from 1.46 to 1.91. The joint effect of BPs mixture and single effect of each BP from the BKMR models were consistent with findings from the linear regression models, further suggesting that associations in girls were generally driven by BPA, BPF, or BPS, while in boys mainly by BPF. ConclusionPrenatal exposure to BPs and their mixture could increase anthropometric measurements of offspring during infancy, with implications of altered growth trajectory in future.

Diagnostic Performance of the Measurement of Skinfold Thickness for Abdominal and Overall Obesity in the Peruvian Population: A 5-Year Cohort Analysis

The escalating prevalence of overall and abdominal obesity, particularly affecting Latin America, underscores the urgent need for accessible and cost-effective predictive methods to address the growing disease burden. This study assessed skinfold thicknesses’ predictive capacity for overall and abdominal obesity in Peruvian adults aged 30 or older over 5 years. Data from the PERU MIGRANT 5-year cohort study were analyzed, defining obesity using BMI and waist circumference. Receiver operating characteristic curves and area under the curve (AUC) with 95% confidence intervals (CI) were calculated. Adults aged ≥ 30 (n = 988) completed the study at baseline, with 47% male. A total of 682 participants were included for overall and abdominal obesity analysis. The 5-year prevalence values for overall and abdominal obesity were 26.7% and 26.6%, respectively. Subscapular skinfold (SS) best predicted overall obesity in men (AUC = 0.81, 95% CI: 0.75–0.88) and women (AUC = 0.77, 95% CI: 0.67–0.88). Regarding abdominal obesity, SS exhibited the highest AUC in men (AUC = 0.83, 95% CI: 0.77–0.89), while SS and the sum of trunk skinfolds showed the highest AUC in women. In secondary analysis excluding participants with type-2 diabetes mellitus (DM2) at baseline, SS significantly predicted DM2 development in men (AUC = 0.70, 95% CI: 0.58–0.83) and bicipital skinfold (BS) did in women (AUC = 0.73, 95% CI: 0.62–0.84). The findings highlight SS significance as an indicator of overall and abdominal obesity in both sexes among Peruvian adults. Additionally, SS, and BS offer robust predictive indicators for DM2.

Understanding the Association Between Obesity and Obstructive Sleep Apnea Syndrome: A Case-Control Study.

Introduction Obstructive sleep apnea (OSA) represents a sleep-related impairment linked to upper airway function. The question of whether OSA drives obesity or if shared underlying factors contribute to both conditions remains unresolved. Hence, this present study aims to understand the interplay between obstructive sleep apnea syndrome (OSAS) and obesity through in-depth analysis of anthropometric data within control subjects and OSA patients. Methodology A case-control study was conducted, which included 40 cases and 40 matched healthy controls. Study participants with reported symptoms of snoring, daytime drowsiness, or both were included in the study. All the study participants underwent comprehensive anthropometric assessments such as height, weight, body mass index (BMI), neck circumference, waist circumference, hip circumference, waist-to-hip ratio, skin-fold thickness, and thickness measurements of biceps, triceps, suprailiac, and subscapular muscles. Results Within the OSA group, significant disparities emerged in mean age, waist circumference, waist-to-hip ratio, and diverse fat accumulations encompassing visceral, subcutaneous, trunk, and subcutaneous leg fat. Notably, skin-fold thickness at specific sites - biceps, triceps, subscapula, and suprailiac - demonstrated considerable augmentation relative to the control group. Furthermore, mean values associated with height, weight, BMI, neck circumference, fat percentage, subcutaneous arm fat, entire arm composition, and trunk skeletal muscle either equaled or exceeded those in the control group. However, statistical significance was not attained in these comparisons. Conclusion This investigation underscored a pronounced correlation between numerous endpoints characterizing OSA patients and markers of obesity. Consequently, addressing altered levels of obesity-linked anthropometric variables through pharmacological interventions might hold promise as a pivotal strategy for improving symptoms associated with OSA.

Correlation between Skinfold Thickness and Total Daily Dose of Insulin in Patient with Type 2 Diabetes Mellitus in Dr Soetomo General Hospital

Introduction: Type 2 diabetes mellitus (T2DM) is a non-communicable disease with a high prevalence in Indonesia. T2DM is caused by insulin resistance and relative insulin deficiency. One of the therapy for T2DM is insulin administration which is injected into the subcutaneous tissue. The absorption of insulin in the subcutaneous tissue is influenced by many factors, one of which is the thickness of subcutaneous fat. This study aimed to determine the correlation between the skinfold thickness of T2DM patients with the total daily dose of insulin needed every day. Methods: This was an observational analytic study using a cross-sectional design to analyze the correlation between subcutaneous fat thickness represented by skinfold thickness and the total daily dose of insulin of T2DM patients. Measurement of skinfold thickness was carried out on the triceps using a skinfold caliper. Data on the patient's total daily dose of insulin were obtained from medical records.Results: A total of 53 patients were included in this study. The patient's mean triceps skinfold thickness was 26.29±8.72 mm. The mean total daily dose of insulin was 40.96±18.01 IU. The results of the Spearman Rank correlation test showed a significant correlation between skinfold thickness on the triceps and the patient's total daily dose of insulin (p<0.05). Conclusion: The higher the skinfold thickness, the greater the dose of insulin needed by the patient.

Skinfold Thickness as a Cardiometabolic Risk Predictor in Sedentary and Active Adult Populations.

Studies report that increased body fat can lead to health risks for individuals. However, some methods used for analyzing adiposity did not identify its distribution in the human body because they are typically measured using bioimpedance scales. This study aims to associate the presence of cardiometabolic risk factors in sedentary and active adult populations through anthropometric methods based on skinfold thickness measurements. A cross-sectional study was conducted on 946 adults aged between 18 and 79 years with prior informed consent. Clinical, anthropometric, and biochemical parameters, as well as some cardiometabolic risk factors, were evaluated. Almost half of the population (45.1%; n = 427) is sedentary. A significant association was found between the sum of the skinfolds (bicipital, tricipital, subscapular, and suprailiac) and the cardiometabolic risk factors evaluated, highlighting the cardiovascular risk associated with abdominal obesity, risk of insulin resistance, as well as the development of hyperglycemia, and hypertriglyceridemia. The bicipital fold was thicker (19.67 mm) in the population with a sedentary lifestyle than in the physically active population (18.30 mm). Furthermore, the skinfolds that predict higher metabolic risks were suprailiac and subscapular in sedentary and active populations. Thus, these skinfold measurements could be considered in assessing the adult population for early cardiometabolic risk detection, even in healthy and physically active people.

Evaluation of Skinfold Techniques in People with Down Syndrome: Development of a New Equation.

The primary aim of this study was to evaluate the accuracy of skinfold thickness (SFT) measurements for the estimation of %Fat when compared to dual energy X-ray absorptiometry (DXA) in individuals with Down syndrome (DS). The secondary aim was to develop a new SFT-based body fat equation (SFTNICKERSON). SFT-based %Fat was estimated using a body fat equation from González-Agüero (SFTG-A) and body density conversion formulas from Siri (SFTSIRI) and Brozek (SFTBROZEK). Criterion %Fat was measured via DXA. SFTG-A, SFTSIRI, and SFTBROZEK were significantly lower than DXA (mean differences ranged from -7.59 to -13.51%; all p < 0.001). The SEE values ranged from 3.47% (SFTBROZEK) to 8.60% (SFTG-A). The 95% limits of agreement were greater than ±10% for all comparisons. Mid-axilla and suprailium were significant predictors of %Fat (both p < 0.05). %Fat SFTNICKERSON = 10.323 + (0.661 × mid-axilla) + (0.712 × suprailium). Age and all other skinfold sites were not statically significant in the regression model (all p > 0.05). Current findings indicate that SFTG-A, SFTSIRI, and SFTBROZEK erroneously place an individual with excessive adiposity in a normal healthy range. Accordingly, the current study developed a new equation (SFTNICKERSON) that can easily be administered in people with DS in a quick and efficient time frame. However, further research is warranted in this area.

Karagenin sebagai Model Inflamasi pada Kulit Punggung Mencit: Gambaran Makroskopik dan Histopatologis

This study aims to create a model of dorsal skin inflammation in mice using carrageenan with various concentrations. Forty-five female Swiss mice with the aged of 8 weeks were used in this study. These mice were divided into three groups of 15. Group I, II and III was given subcutaneous injection of 1%, 2% and 4% carrageenan respectively on the dorsum. Carrageenan was dissolved in 0.9% buffer saline with 0.1 mL volume injection. Prior to carrageenan injection, dorsal skin-fold thickness was measured using calipers and then was repeated every hour up to 6 hours. At the end of the sixth hour of measuring skin-fold thickness, animal was sacrificed, the dorsal skin was excised and then was fixed in 10% buffer formalin for histopathological examination. Data from skin-fold thickness measurement was analyzed using Two Ways Anova followed by Tukey HSD test. Results of this study demonstrate that there was a significant difference in skin-fold thickness between treatment groups (p&lt;0.05). Sub cutaneous injection of 1%, 2% and 4% carrageenan resulted in increasing skin-fold thickness approximately 35%, 50% and 61% at the one-hour post carrageenan injection respectively (p&lt;0.05). Skin-fold thickness gradually decreased at the second to the sixth hour after carrageenan injection. Histopathological examination shows mild and moderate dermal inflammation in the group given 1% and 2% carrageenan respectively. Severe dermal and panniculus inflammation was found in the group given 4% carrageenan. To conclude, carrageenan could be used to induce inflammation in back skin of mice.

Comparison of total body potassium with other techniques for measuring lean body mass in men and women with AIDS wasting

Lean body mass is an important predictor of survival and functional status in patients with AIDS wasting. The bias between different techniques for assessing body composition in AIDS wasting is not known. We compared total body potassium (TBK) with fat-free mass (FFM) determined by dual-energy X-ray absorptiometry (DXA), bioelectrical impedance analysis (BIA), and skinfold-thickness measurement (SKF) in 132 patients (63 men, 69 women) with AIDS wasting (weight < 90% of ideal body weight, or weight loss > 10% of original, or both). None of the subjects exhibited clinical lipodystrophy. Comparisons were made by using different BIA equations. Lean body mass determined by DXA was highly correlated with TBK in men (r = 0.79, P: < 0.0001) and women (r = 0.84, P: < 0.0001). FFM(BIA) and FFM(DXA) were significantly different (P: < 0.01 in men and P: < 0.0001 in women). The difference between FFM(DXA) and FFM(BIA) was significantly greater with greater weight and body fat, particularly in HIV-infected women (r = -0.39, P: = 0.001 for weight; r = -0.60, P: < 0.0001 for fat). The comparability of FFM and fat mass determined by DXA and BIA was dependent on the specific BIA equation used. Among men, no single BIA equation was more highly predictive of fat mass and FFM in comparison with DXA. The differences between DXA, BIA, and SKF in the determination of fat mass and FFM are significant in patients with AIDS wasting. BIA overestimates FFM compared with DXA in those with greater body fat. Standard BIA equations may not accurately estimate FFM and fat mass in men and women with AIDS wasting.

Using A-Mode Ultrasound to Assess the Body Composition of Soccer Players: A Comparative Study of Prediction Formulas.

For elite athletes, monitoring body composition is important for maximizing performance without health risks. Amplitude (A)-mode ultrasound (AUS) has attracted increasing attention as an alternative to skinfold thickness measurements commonly used for assessing the amount of body fat in athletes. AUS accuracy and precision, however, depend on the formula used to predict body fat percentage (%BF) from subcutaneous fat layer thicknesses. Therefore, this study evaluates the accuracy of the 1-point biceps (B1), 9-sites Parrillo, 3-sites Jackson and Pollock (JP3), and 7-sites Jackson and Pollock (JP7) formulas. Relying on the previous validation of the JP3 formula in college-aged male athletes, we took AUS measurements in 54 professional soccer players (aged 22.9 ± 3.83 y, mean ± SD) and compared the results given by different formulas. The Kruskal-Wallis test indicated significant differences (p < 10-6), and Conover's post hoc test revealed that the JP3 and JP7 data come from the same distribution, whereas the data given by B1 and P9 differ from all the others. Lin's concordance correlation coefficients for B1 vs. JP7, P9 vs. JP7, and JP3 vs. JP7 were 0.464, 0.341, and 0.909, respectively. The Bland-Altman analysis indicated mean differences of -0.5 %BF between JP3 and JP7, 4.7 %BF between P9 and JP7, and 3.1 %BF between B1 and JP7. This study suggests that JP7 and JP3 are equally valid, whereas P9 and B1 overestimate %BF in athletes.

Genetic regulation of body size and morphology in children: a twin study of 22 anthropometric traits

BackgroundAnthropometric measures show high heritability, and genetic correlations have been found between obesity-related traits. However, we lack a comprehensive analysis of the genetic background of human body morphology using detailed anthropometric measures.MethodsHeight, weight, 7 skinfold thicknesses, 7 body circumferences and 4 body diameters (skeletal breaths) were measured in 214 pairs of twin children aged 3–18 years (87 monozygotic pairs) in the Autonomous Region of Madeira, Portugal. Factor analysis (Varimax rotation) was used to analyze the underlying structure of body physique. Genetic twin modeling was used to estimate genetic and environmental contributions to the variation and co-variation of the anthropometric traits.ResultsTogether, two factors explained 80% of the variation of all 22 anthropometric traits in boys and 73% in girls. Obesity measures (body mass index, skinfold thickness measures, as well as waist and hip circumferences) and limb circumferences loaded most strongly on the first factor, whereas height and body diameters loaded especially on the second factor. These factors as well as all anthropometric measures showed high heritability (80% or more for most of the traits), whereas the rest of the variation was explained by environmental factors not shared by co-twins. Obesity measures showed high genetic correlations (0.75–0.98). Height showed the highest genetic correlations with body diameter measures (0.58–0.76). Correlations between environmental factors not shared by co-twins were weaker than the genetic correlations but still substantial. The correlation patterns were roughly similar in boys and girls.ConclusionsOur results show high genetic correlations underlying the human body physique, suggesting that there are sets of genes widely affecting anthropometric traits. Better knowledge of these genetic variants can help to understand the development of obesity and other features of the human physique.

O tamanho da pinça pode afetar a medida de espessura das dobras cutâneas e interferir na estimativa e classificação da adiposidade corporal

Abstract The aim of this study was to verify the effect of pinch size on skinfold thickness measurement and the consequent interference in the estimation and classification of body adiposity components. Cross-sectional and quantitative study carried out with a sample of 29 subjects recruited from a university in the city of Fortaleza, Ceará, Brazil. Four measurement steps were performed at each site of the eight chosen skinfolds. The first step was performed with a subjective-landmark and the three subsequent steps with fixed-landmarks defined with an expanding secondary line at 2 cm intervals. Body adiposity components were determined from the skinfold thickness measured at each landmark. Repeated measures ANOVA and Bland-Altman agreement analysis were applied. The subjective-landmark was chosen as the dependent variable. The 6 cm-landmark showed similarity and statistical agreement with the subjective-landmark for all skinfolds except the thigh, and with the sums of five and eight skinfolds. All fixed-landmarks showed agreement below the cut-off point for the percentile classification of subcutaneous adiposity and normative relative body fat. Variation in pinch size is an important source of TEM that can affect the reproducibility of skinfold thickness measurements and interfere in the estimation and classification of the molecular and tissue component of body adiposity.

Agreement and validity between body fat estimated by skinfold measurement and air displacement plethysmography in adolescents

Objective: Assess the agreement and validity between relative body fat percentages estimated using anthropometric measurements and air displacement plethysmography (ADP). Methods: A cross-sectional study was conducted on 118 adolescents (60 females) aged 10 to 14 years (x̄=12.19, sd=1.18). Adolescents were classified as eutrophic or with overweight according to body mass index (body weight/height2) (x̄=20,12, sd=3,56). Measurements of skinfold thickness (triceps and medial calf) were collected and used to estimate relative body fat by the Slaughter equation. ADP was used as a reference method for the estimation of relative body fat. Agreement between body fat measurement methods (anthropometry × ADP) was analyzed by the Bland–Altman method. The mean error (ME) was calculated by subtracting the body fat percentage estimated by the Slaughter equation from the body fat percentage estimated by ADP. Validity was tested with the concordance correlation coefficient (CCC). Results: There was no agreement between the methods, regardless of sex and weight status. For boys with overweight (ME = 4.52; p = 0.007), eutrophic girls (ME = 6.37; p &lt; 0.001), and girls with overweight (ME = 5.55; p &lt; 0.001), the Slaughter equation resulted in overestimation of body fat compared with ADP. Skinfold equations did not demonstrate validity when compared with ADP. Conclusion: Slaughter's skinfold equations did not demonstrate agreement and validity compared with ADP in either sex or weight status. Skinfold equations should be used with caution and, whenever possible, in combination with other body composition indicators.

Examining of some physical and physiological parameters of 10-18 years old male skiers to seasonal cycles

Abstract: Skiing can be identified as a branch with the most important representative power of winter sports. Further, it has been characterized by high popularity and population, branching off in itself. During the year, different physical performance and physiological indicators are sometimes encountered in athletes depending on seasonal cycles, training levels, and living conditions. The aim of this study is to examine some physical performance parameters and the determined hormone levels to seasonal cycles. Methods: 15 male skiers with a mean age of 14.53±2.61 (years), a mean height of 158.53±9.66 (cm), and a mean body mass of 54.20±10.85 (kg) participated in the study. The information about participants' age, height, and body mass was determined by standard methods. Various measurement tools were used including a digital hand dynamometer (TKK 5401) for hand grip strength, a digital dynamometer (TKK 5402) for back and leg strength, a jump meter (Takei TKK 5406) for vertical jump height, and an electronic hand spirometer (firstMED) for respiratory functions. The Wingate anaerobic power test (Monark 894 E bicycle ergometer) was performed to determine the anaerobic power level. Additionally, to determine somatotypes (ectomorph, mesomorph, endomorph) and body fat percentage; skinfold caliper (Holtain), tape measure, and digital caliper (Holtain) were respectively utilized for skinfold thickness measurement, circumference measurements, and diameter measurements. Blood samples (hemogram test, vitamin D, cortisol, and testosterone to be checked) were taken from the antecubital vein in the sitting position. From the blood samples, serum plasma was separated and preserved by centrifugation (+4o) and all samples were analyzed at once. All tests were performed once in September, December, March, and June at an altitude of 2,000 and in pre-season and mid-season. The data were analyzed through IBM SPSS 24.0 package program. Shapiro-Wilk was used to determine the distribution of the data, descriptive and frequency analysis was used to determine the mean of the variables, and one-way analysis of variance (ANOVA) was used to determine the differences between measurements. The results were presented as arithmetic mean and standard deviation (𝑋̅±Ss). Results: In 10-18 years old male skiers, it was determined that vitamin D reached its highest level in autumn, testosterone in summer, and cortisol in winter. In the inter-test comparison results, significant differences were determined in the vertical jump, right and left-hand grip strength, leg strength, testosterone, vitamin D, HCT, FVC, FEV1, and anaerobic power parameters. Conclusions: The results of the study have mostly supported the literature. Keywords: vitamin D; testosterone; cortisol; anaerobic power; respiratory functions

21. yüzyılın en önemli sağlık problemi: Yaşam dönemlerine göre obezitenin incelenmesi

Obesity is a complex disease involving an excessive amount of body fat and an important public health problem affecting all ages in both men and women. It has been shown that obesity is responsible for many genetic, environmental, neurological, physiological, biochemical, cultural and spiritual factors. World Health Organization (WHO) recommends Body Mass Index (BMI) for obesity classification due to its simplicity, cost-effectivity, and high accuracy. Apart from BMI, waist circumference measurement, weight-to-height, skinfold thickness, and circumference measurements are also used. According to the WHO, 2.8 million people die every year due to obesity. Although obesity affects all ages and social groups, women have been more overweight compared to men since and has been linked to many biological factors. However, even with the medical problems, obese women live longer than men, but not without higher healthcare costs. In this review, the effects of obesity on women's health and life will be discussed.

Differences in Body Composition Analysis by DEXA, Skinfold and BIA Methods in Young Football Players.

The most widely used method in professional sports for fat percentage assessment is the skinfold method. However, there is the chance of bias and human error. For this reason, other more precise methods are used, such as single-frequency bioelectrical impedance analysis (BIA) or dual energy X-ray absorptiometry (DEXA). However, there are limited data that demonstrate the methodological shortcomings or congruences in fat and fat-free mass estimates including gender differences and differences in athlete populations. Thus, the aim of the present study was to compare total body fat (%BF) estimated by six skinfold thickness measurement (SKF) and single-frequency bioelectrical impedance analysis (BIA) methods, using three different sets of equations, to that assessed by the dual energy X-ray absorptiometry (DEXA) method using a DEXA Hologic Serie Discovery QDR. For this aim, 76 males and 70 females belonging to the professional Spanish football federation were evaluated. We found significant differences between the three measures. BIA significantly underestimates the fat percentage, followed by skinfolds. With DEXA being the more objective or accurate method, an equation is established by means of linear regression analysis that allows the percentage of adipose tissue to be obtained either through anthropometry or electrical bioimpedance and adjusted to that which would be obtained by the DEXA system.

Prediction and validation of total and regional skeletal muscle volume by using anthropometric measurements in prepubertal Japanese children.

It is difficult to easily estimate skeletal muscle (SM) volume in children. We aimed to develop regression-based prediction equations to estimate the total body and regional SM volume using calliper measurements of skinfold thickness and limb circumference and to investigate the validity of these equations. In total, 142 healthy, prepubertal, Japanese children, aged 6-12 years, were divided into two groups: the model development group (sixty boys, thirty-eight girls) and the validation group (twenty-six boys, eighteen girls). Contiguous magnetic resonance images were obtained from the first cervical vertebra to the ankle joints as reference data. SM volume was calculated from the summation of the digitised cross-sectional areas. Limb and waist circumferences were measured at mid-upper arm, mid-thigh, maximal calf and at the level of umbilicus. Each girth was corrected for subcutaneous adipose tissue thickness, as estimated by skinfold thickness measurements. Skinfold thickness was measured at the posterior upper arm, anterior thigh, medial calf and lateral to the umbilicus, using callipers. Significant correlations were observed between the site-matched SM volume, measured by MRI, and each corrected girth × standing height value in the model development group. When these SM volume prediction equations were applied to the validation group, the measured total body and regional SM volume were similar to the predicted values. These results suggest that the anthropometric prediction equations developed in this study provide reliable information about the total and regional SM volume in prepubertal Japanese children, with varying degrees of estimation accuracy for each region.

The Relationship of Resistin with Disease Severity, Inflammation and Insulin Resistance in Cirrhosis Patients

Introduction: Glucose intolerance has been shown to play an important role in the progression of early liver disease to cirrhosis. It has been suggested that insulin resistance is responsible for glucose intolerance in patients with chronic liver disease. It is thought that increased resistin through chronic inflammation in chronic liver disease may be responsible for insulin resistance. In our study, we aimed to evaluate the relationship of resistin which is released from adipose tissue with insulin resistance, inflammation markers and disease stage in patients with cirrhosis. Methods: Forty-six patients diagnosed with cirrhosis in Eskişehir Osmangazi University Faculty of Medicine, Department of Gastroenterology between March 2008 and July 2009, and 19 healthy individuals as a control group were included in the study. Patients with a diagnosis of Diabetes Mellitus, other endocrine disease or Hepatocellular Carcinoma, with fasting blood glucose above 126 mg/dl and using drugs that may affect glucose metabolism were excluded from the study. Participants with obesity were determined by skinfold thickness (biceps, triceps, suprailiac and subscapular) measurement. Statistical analyzes were performed by excluding obese patients from the study and control groups. AssayMax Human Resistin ELISA Kit was used to determine serum resistin level. The "Homaostatic Model for Insulin Resistance" (HOMA-IR) formula was used to detect insulin resistance. The studied parameters were statistically compared between the study and control groups and also between the three groups (Child Pugh stage A, B and C) formed according to the disease stage in the study group. Results: All laboratory parameters reflecting insulin resistance, inflammation markers and resistin levels were found to be significantly higher in the study group. As the Child Pugh stage advances, which is used to determine the severity and prognosis of the disease, resistin levels found higher, but it was observed that the rate of patients with decreased insulin resistance had lower levels in total fat ratio. No significant correlation was found between resistin and other markers of insulin resistance except fasting insulin level. Conclusion: In the future metabolism studies which to be performed in patients with cirrhosis detection of skinfold thickness may be useful in determining body fat ratio. Insulin resistance markers are significantly higher in patients with cirrhosis, as disease severity advances resistin levels increases. We are in the opinion that resistin does not contribute to the development of insulin resistance, which occurs with different mechanisms in patients with cirrhosis.

The effect of calf and thigh circumferences in determining brain lesion characteristics in patients with acute stroke: A hospital-based study

The role of stroke risk factors in stroke patterning and differentiation is poorly investigated, especially for measures of body composition. This study aimed to investigate the effect of skinfold thickness, waist and limb circumference measurements in patterning and differentiation of stroke in hospitalized patients. Prospective study of acute stroke patients hospitalized in Aminu Kano Teaching Hospital in Nigeria was conducted in 16 months. Biceps brachii, triceps brachii, suprailiac and subscapular skinfold thickness measurements were taken using Skyndex Research Caliper. Upper arm, waist, thigh, and calf circumferences were taken, using an inelastic measuring tape according to the same standards. The data was analyzed using descriptive statistics, unpaired sample t-test, and Binary logistic regression using SPSS IBM version 20. The results shown that the studied anthropometric parameters, do not only predispose to stroke but tend to determine the specific stroke pathologic type. Thigh circumference predisposes more, and calf circumference predisposes less to ischemic stroke subtype. This means that these studied anthropometric parameters can predict stroke subtype and serve as predisposing factors conclusively.

Association of Birth Weight, Body Composition and Blood Pressure During Infancy in 1-Year-Old Jamaican Children

ObjectivesTo investigate the association of birth weight (BW), body composition (BC), and blood pressure (BP) in healthy, one-year-old infants in Jamaica.MethodsA cross-sectional study where fat-free mass (FFM) and fat mass (FM) was assessed by whole-body bioelectrical impedance analysis (BIA) and skinfold thickness measurements in a sample of 101 healthy one-year-old infants (58 girls and 43 boys). Oscillometric Blood Pressure was measured in triplicate in each infant. The main independent variable was birth weight. Pearson's correlation test and multiple linear regression were used to analyze the association between birth weight and body composition and blood pressure..ResultsSignificant associations were observed between birth weight and fat-free mass(r = 0.35.p = 0.0001) and fat mass(r = 0.25.p = 0.013) at the simple bivariate level, weight, and length significantly correlated with body composition using the multiple linear regression. 12% of girls and 265 of boys had excess body fat. The mean BP was 110/67 mm Hg for boys and 108/67 mm Hg for girls. At the bivariate level, birth weight was significantly correlated with systolic blood pressure (r = 0.21, p = 0.019). There was no association between birth weight and blood pressure in the regression models. Socioeconomic status did not impact the association of birth weight and body composition in this study. Significant associations were observed between birth weight and fat-free mass(r = 0.35.p = 0.0001) and fat mass(r = 0.25.p = 0.013) at the simple bivariate level, weight, and length significantly correlated with body composition using the multiple linear regression. 12% of girls and 265 of boys had excess body fat. The mean BP was 110/67 mm Hg for boys and 108/67 mm Hg for girls. At the bivariate level, birth weight was significantly correlated with systolic blood pressure (r = 0.21, p = 0.019). There was no association between birth weight and blood pressure in the regression models. Socioeconomic status did not impact the association of birth weight and body composition in this study.ConclusionsIn this sample of one-year-old infants, birth weight was associated with fat-free mass and fat mass, and weight and length were associated with fat-free mass, fat mass, and percentage body fat.Funding SourcesThis research was not funded.