Measurement Of Zinc In Plasma Research Articles

Zinc function in childhood brain

Zinc is essential in the metabolic activities in the body including protein, DNA and RNA synthesis. It plays a role in neurogenesis, maturation, and migration of neurons and in synapse formation. Zinc is high in the hippocampal neurons which is involved in learning and memory. Deficiency of zinc during pregnancy has been related to many congenital abnormalities of the foetal nervous system. Furthermore insufficient levels of zinc in children is associated with lowered learning ability, apathy, lethargy and mental retardation. Maternal deficiency of zinc during lactation has been associated with impairment of infant brain development. Zinc status in mother and child can be assessed by measurement of zinc in plasma; zinc deficiency can be corrected with appropriate diet and zinc supplements. Red meat, poultry items, oysters, cashew nuts and almonds are rich sources of zinc.

Laboratory diagnosis of zinc deficiency.

Zinc status in human subjects is assessed by measurement of zinc in plasma, erythrocytes, neutrophils, lymphocytes, and hair. Available data indicate that zinc in neutrophils and the assay of activity of alkaline phosphatase in neutrophils may be the best tools for the diagnosis of zinc deficiency. Measurement of zinc in the plasma is simple and readily available in many laboratories. Plasma zinc is useful provided the plasma is unhemolyzed and conditions, such as infections, acute stress, myocardial infarction and intravascular hemolysis, are ruled out. Inasmuch as hair and erythrocytes turn over slowly, their zinc levels do not reflect recent changes with respect to zinc status. Other useful parameters for assessment of zinc status include metabolic balance studies, urinary zinc excretion. Cu:Zn ratio, zinc tolerance test, and measurement of activities of zinc-dependent enzymes in suitable biological samples.

Criticism of the proposed selected method: direct measurement of zinc in plasma by atomic absorption spectroscopy.

Journal Article Criticism of the proposed selected method: direct measurement of zinc in plasma by atomic absorption spectroscopy. Get access J R Kelson J R Kelson Search for other works by this author on: Oxford Academic Google Scholar Clinical Chemistry, Volume 26, Issue 2, 1 February 1980, Pages 349–350, https://doi.org/10.1093/clinchem/26.2.349 Published: 01 February 1980

In Reply: Criticism of the Proposed Selected Method: Direct Measurement of Zinc in Plasma by Atomic Absorption Spectroscopy

In Reply: Criticism of the Proposed Selected Method: Direct Measurement of Zinc in Plasma by Atomic Absorption Spectroscopy

Criticism of the proposed selected method: direct measurement of zinc in plasma by atomic absorption spectroscopy.

Criticism of the proposed selected method: direct measurement of zinc in plasma by atomic absorption spectroscopy.

In Reply: Criticism of the Proposed Selected Method: Direct Measurement of Zinc in Plasma by Atomic Absorption Spectroscopy

In Reply: Criticism of the Proposed Selected Method: Direct Measurement of Zinc in Plasma by Atomic Absorption Spectroscopy

Direct measurement of zinc in plasma by atomic absorption spectroscopy.

Direct measurement of zinc in plasma by atomic absorption spectroscopy.