Accurately and instantly estimating the hydrodynamic characteristics in two-phase liquid–gas flow is crucial for industries like oil, gas, and other multiphase flow sectors to reduce costs and emissions, boost efficiency, and enhance operational safety. This type of flow involves constant slippage between gas and liquid phases caused by a deformable interface, resulting in changes in gas volumetric fraction and the creation of structures known as flow patterns. Empirical and numerical methods used for prediction often result in significant inaccuracies during scale-up processes. Different methodologies based on artificial intelligence (AI) are currently being applied to predict hydrodynamic characteristics in two-phase liquid–gas flow, which was corroborated with the bibliometric analysis where AI techniques were found to have been applied in flow pattern recognition, volumetric fraction determination for each fluid, and pressure gradient estimation. The results revealed that a total of 178 keywords in 70 articles, 29 of which reached the threshold (machine learning, flow pattern, two-phase flow, artificial intelligence, and neural networks as the high predominance), were published mainly in Flow Measurement and Instrumentation. This journal has the highest number of published articles related to the studied topic, with nine articles. The most relevant author is Efteknari-Zadeh, E, from the Institute of Optics and Quantum Electronics.