Measles-rubella Vaccination Campaign Research Articles

Real Effects of Loss of Vaccination will be known in Coming Times Reply to Measles-Rubella Vaccination Campaign: Pandemic as Speed Breaker

Real Effects of Loss of Vaccination will be known in Coming Times Reply to Measles-Rubella Vaccination Campaign: Pandemic as Speed Breaker

An evaluation of the early impact of the COVID-19 pandemic on Zambia's routine immunization program.

Implications of the COVID-19 pandemic for both populations and healthcare systems are vast. In addition to morbidity and mortality from COVID-19, the pandemic also disrupted local health systems, including reductions or delays in routine vaccination services and catch-up vaccination campaigns. These disruptions could lead to outbreaks of other infectious diseases that result in an additional burden of disease and strain on the healthcare system. We evaluated the impact of the COVID-19 pandemic on Zambia's routine childhood immunization program in 2020 using multiple sources of data. We relied on administrative vaccination data and Zambia's 2018 Demographic and Health Survey to project national disruptions to district-specific routine childhood vaccination coverage within the pandemic year 2020. Next, we leveraged a 2016 population-based serological survey to predict age-specific measles seroprevalence and assessed the impact of changes in vaccination coverage on measles outbreak risk in each district. We found minor disruptions to routine administration of measles-rubella and pentavalent vaccines in 2020. This was in part due to Zambia's Child Health Week held in June of 2020 which helped to reach children missed during the first six months of the year. We estimated that the two-month delay in a measles-rubella vaccination campaign, originally planned for September of 2020 but conducted in November of 2020 as a result of the pandemic, had little impact on modeled district-specific measles outbreak risks. This study estimated minimal increases in the number of children missed by vaccination services in Zambia during 2020. However, the ongoing SARS-CoV-2 transmission since our analysis concluded means efforts to maintain routine immunization services and minimize the risk of measles outbreaks will continue to be critical. The methodological framework developed in this analysis relied on routinely collected data to estimate disruptions of the COVID-19 pandemic to national routine vaccination program performance and its impact on children missed at the subnational level can be deployed in other countries or for other vaccines.

When religion prevails: examining religious and mainstream news coverage of measles-rubella vaccination in Indonesia

ObjectivesIndonesia's measles-rubella (MR) vaccination campaign faced public refusal due to religious objections. The government then lobbied the religious organization to issue a decree to permit the consumption of the MR vaccine, which would enhance public approval. Media outlets, including religious and mainstream media, played a crucial role in promoting the decree and the vaccine. Learning from this MR vaccination campaign in 2018, this study examined how the mainstream and alternative or religious media framed the MR vaccination and how it changed before and after the decree. Study design/methodsA content analysis was performed on 234 news articles from Indonesian religious and mainstream media. ResultsMainstream media positively framed MR vaccines, which were further amplified after the decree was issued. In contrast, religious media consistently depicted the opposing sides of the vaccine and its campaign. Both media types also predominantly cited the government and religious leaders in their articles. ConclusionWhile the mainstream media agenda aligns with the national agenda to promote the MR vaccine, religious media still emphasizes the risk of the vaccine. The prevalence of religious leaders in alternative media also suggests that the public, including religious leaders, may not necessarily accept the decree. Hence, more effort should be devoted to encouraging the media and religious leaders to accept the vaccine, as they may act as opinion leaders.

Real effects of loss of vaccination will be known in coming times reply to Measles-Rubella vaccination campaign: Pandemic as speed breaker

Real effects of loss of vaccination will be known in coming times reply to Measles-Rubella vaccination campaign: Pandemic as speed breaker

A study to estimate the coverage of measles rubella vaccination campaign and various reasons for non-immunization: An observational study

A study to estimate the coverage of measles rubella vaccination campaign and various reasons for non-immunization: An observational study

Measles-Rubella Positivity Rate and Associated Factors in Pre-Mass and Post-Mass Vaccination Periods: Analysis of Uganda Routine Surveillance Laboratory Data

Toward 2019, Uganda experienced an extensive outbreak of measles and rubella. The Uganda National Expanded Programme on Immunization implemented a mass measles-rubella vaccination campaign aimed at halting the ongoing transmission. This study determined the changes in the disease burden thereafter. We conducted a retrospective cross-sectional study on measles-rubella positivity and its associated factors in Uganda using 1697 case-based surveillance data for 2019 and 2020 stratified into two dispensations: prevaccination and postvaccination campaigns. Statistical tests employed in STATA 15 included chi-square, Fisher’s exact, and binomial tests. Measles positivity rates in the period before and after the mass immunization campaign were 41.88% (95% CI: 39.30–44.51) and 37.96% (95% CI: 32.81–43.40), respectively. For rubella, the positivity rate in the precampaign season was 21.73% (95% CI: 19.61–23.99) and in the postvaccination season was 6.65% (95% CI: 4.36–10.00). Binomial tests indicated that postcampaign positivity rates were significantly lower than the precampaign rate for measles ( p = 0.003 ) and rubella ( p < 0.001 ). Generally, age (χ2 = 58.94, p = 0.001 /χ2 = 51.91, p < 0.001 ) and vaccination status (χ2 = 60.48, p = 0.001 /χ2 = 16.90, p = 0.001 ) were associated with the measles positivity rate in both pre/postcampaign periods. Rubella positivity rate was associated with vaccination status (χ2 = 32.97, p < 0.001 / p = 0.001 ) in both periods and age in the precampaign season ( p < 0.001 ). The measles-rubella mass campaign lessened rubella burden remarkably, but barely adequate change was observed in the extent of spread of measles. Children aged less than 9 months are at higher chances of testing positive amidst low vaccination levels among the eligible. The immunization programme must attain and maintain routine immunization coverage at 95% or more and roll out a second-dose measles-rubella vaccination to sustain the reduced disease burden.

Nepal measles outbreak response immunization during COVID-19: A risk-based intervention strategy

In 2020, National Immunization Programme (NIP) of Nepal implemented a measles outbreak response immunization (ORI) campaign, which was additional to an ongoing preventive measles-rubella SIA campaign. Both campaigns were implemented during ongoing COVID-19 transmission. By April, 220 measles cases and two deaths were confirmed from eight districts of Nepal. The NIP triangulated information from surveillance (measles and COVID-19), measles immunization performance and immunity profile, programme capacities and community engagement and applied a logical decision-making framework to the collated data to inform ‘Go/No-Go’ decisions for ORI interventions. This was reviewed by the National Immunization Advisory Committee (NIAC) for endorsement. Outbreak response with non-selective immunization (ORI), vitamin-A administration and case management were implemented in affected municipalities of four districts, while in the remaining districts outbreak response without ORI were undertaken. The structure and iterative application of this logical framework has been described. ORI was implemented without interrupting the ongoing measles-rubella vaccination campaign which had targeted children from 9 to 59 months of age. The age group for ORI was same as SIA in one sub-district area, while for the other three sub-district areas it was from 6 months to 15 years of age. More than 32,000 persons (97% coverage) were vaccinated in ORI response. Overall measles incidence decreased by 98% after ORI. The daily incidence rate of measles was 94 times higher (95% confidence interval: 36.11 – 347.62) before the ORI compared to two weeks after ORI until year end. Close attention to surveillance and other data to inform actions and seamless collaboration between NIP and core immunization partners (WHO, UNICEF), with guidance from NIAC were key elements in successful implementation. This was an example of feasible application of the global framework for implementation of a mass vaccination campaign during COVID-19 through application of a simple decision-making logical framework.

Measles-Rubella vaccination campaign: Pandemic as speed breaker

Background: Infectious diseases such as measles and rubella (MR) spread quickly to infect vulnerable populations, especially children below 5 years. Mass vaccination had been implemented to prevent it and its success has been observed through decreasing numbers of cases. The Government of India started MR campaign in February 2017, and Maharashtra was one of the selected states for it. The study was planned to find out the trend of measles cases before and after MR campaign and also to find out the effect of lockdown due to pandemic on vaccine usage. Aim: The aim of this study is to find out the trend of MR cases before and after MR campaign. Materials and Methods: A Descriptive observational study was done in tertiary care center for 2 years. Measles cases from the past 5 years were taken, and the impact of MR campaign was seen. Lockdown due to COVID-19 pandemic had an impact on the vaccination drive. To find out the impact, data for different vaccines were collected from different health centers, and analysis was done in Epi-info. Results: Post MR campaign, there was a sharp decrease in measles cases. Measles mostly targeted children below 6 years, and infants were seen having the longest stay in hospital due to the infection. At the onset of lockdown due to pandemic, vaccine consumption has gone down everywhere in the study. Conclusion: Vaccination is a proven weapon to prevent vaccine-preventable diseases, and measles is no different from other infectious diseases. Lockdown hindered the process of mass vaccination of vaccine-preventable diseases and which has gone down everywhere.

Congenital Rubella Syndrome Surveillance After Measles Rubella Vaccination Introduction in Yogyakarta, Indonesia.

Congenital rubella syndrome (CRS) is a fatal disease causing severe congenital defects. Indonesia had the highest CRS cases in the world in 2016 with a commitment to achieve elimination of rubella disease by 2020, through the campaign and introduction of measles rubella (MR) national vaccination program in 2017 and 2018. This study aimed to describe the impact of the national vaccination campaign by conducting surveillance of CRS cases and comparing the incidence of new CRS cases before and after the MR vaccination campaign. From July 2015 to July 2020, we conducted surveillance of CRS in Yogyakarta. Suspected patients underwent complete clinical examinations. Serology was tested for the presence of IgM and IgG antibodies against rubella. Descriptive analysis was used to characterize the demographic and clinical characteristics of the cases before and after the MR vaccination campaign. The study involved 229 infants who were suspected for CRS. Laboratory-confirmed cases were found in 47 of them (20.86%). Most of the laboratory-confirmed cases (55.3%) were reported among 1-5 months old infants. Common clinical features among laboratory-confirmed cases included structural heart defects in 43 (91.4%). There was a significant decrease (60.9%) of CRS incidence from 0.39 per 1000 live births in the precampaign era to 0.08 in the postcampaign era (P = 0.00). There has been a significant declining number of CRS cases based on pre- and post-MR vaccination campaign in Yogyakarta, Indonesia. An effective surveillance system will help monitor the number of CRS cases.

Cost of conducting Measles-Rubella vaccination campaign in India

ABSTRACT A Measles-Rubella (MR) vaccination campaign was launched in India in a phased manner in February 2017 to cover children aged 9 months to 15 years. As evidence on campaign vaccine delivery costs is limited, the delivery cost for MR campaign from a government provider perspective was estimated in four Indian states, namely, Assam, Gujarat, Himachal Pradesh, and Uttar Pradesh. Costs were calculated in top-down and bottom-up approaches using data collected from 84 sites at different administrative levels and immunization partners in the study states from August 2019 to March 2020. All costs were presented in 2019 US$ and Indian Rupee (INR). The financial cost per dose of the MR campaign including all partner support ranged from US$0.16 (INR 10.95) in Uttar Pradesh to US$0.34 (INR 24.13) in Gujarat. In Uttar Pradesh, the full economic cost per dose was US$0.87 (INR 61.39). The key financial cost drivers were incentives related to service delivery and supervision, the printing of reporting formats for record-keeping, social mobilization, and advocacy. The financial delivery cost per dose estimated was higher than the government pre-fixed budget per child for the MR campaign, probably indicating an insufficient budget. However, the study found underutilization of MR budget in two states and use of other sources of funding for the campaign indicating the need for proper utilization of the campaign budgets by the states. Unit cost information generated from this study will be useful for planning, cost projections, and economic analysis of future vaccination campaigns in India.

Measles outbreak investigation in a highly vaccinated community in the Centre region of Cameroon.

BackgroundMeasles remains a threat in many African settings due to sub-optimal routine immunisation and catchup campaigns. The Global Vaccine Action Plan goal to eliminate measles by 2020 remains unmet as several countries reported an increase in cases in 2019. In Cameroon, a measles-rubella vaccination campaign was organised in 2019 to reduce the cohort of susceptible children. However, in 2020, eleven suspected cases of measles were notified in the Sa’a Health District and five were confirmed.ObjectiveThis report summarizes a measles outbreak investigation and contact tracing in a highly vaccinated community residing in the Sa’a Health District of Cameroon.MethodsOutbreak investigations were carried out in the Sa’a, Nlong-Onambele and Nkolmgbana health areas from 18 to 21 February 2020. A register review from December 2019 to February 2020 was carried out in all health facilities of the affected health areas. followed by contact tracing in the community.ResultsThirty households were visited in four neighbourhoods. Six missed Epidemiologically-linked cases were discovered in the community, bringing the total number of suspected and confirmed cases to 17. Thirty-five percent of the cases had not received any measles-containing vaccine; 35% of the cases were aged 5 years or older; 53% had history of travel. Community transmission only occurred in the Sa’a health area through a breakthrough case.ConclusionsThis outbreak investigation portrayed the role that adequate vaccination coverage plays in preventing widespread outbreaks. Nonetheless, community sensitisation and routine immunisation require strengthening in order to erase pockets of susceptible children.

Media news on vaccines and vaccination: The content profile, sentiment and trend of the online mass media during 2015–2020 in India

BackgroundThe immunization coverage progress in India is relatively slower than anticipated. The rising internet and media penetration and online news contents are likely to shape the public vaccine sentiments and attitude. The measles-rubella immunization campaign in India experienced challenges in some states due to the social media and messaging. This study studied the profile and vaccine sentiments of the online media news in India. MethodsWe retrieved the online news on immunization and vaccines published in English during November 2015 to May 2020. The news were analysed for contents and categorised as positive, negative and neutral sentiments. ResultsOut of 2626 news retrieved, 1788 eligible ones were analysed. The news focused on immunization program in 59.1% and vaccine hesitancy in 7.7% items. While 42.5% news originated from national level, 33.2% were from six states. Measles-rubella was the leading vaccine in the news (23.2%) followed by coronavirus (12.8%), poliomyelitis (10.4%) and rotavirus (5.1%) vaccines. While 71.4% news conveyed positive sentiment, 23.8% and 4.7% had negative and neutral sentiments, respectively. The negative sentiments focused on adverse events, vaccine hesitancy and resistance. The news volume and negative sentiments were largely linked to the measles-rubella vaccination campaign phases in India. ConclusionsNegative vaccine news constitute a sizable proportion of the online news and can influence the public vaccine sentiment and attitude. The experiences of public response towards measles-rubella, pentavalent and human papillomavirus vaccines suggest necessity of comprehensive media mapping and tracking to guide appropriately to sustain the public vaccine confidence and improve coverage.

A study to estimate the coverage of measles rubella vaccination campaign in urban field practice area of MR Medical College, Kalaburagi, Karnataka

Introduction: Measles and rubella are among the most infectious diseases of humans. Seroprevalence studies suggest that coverage in the range of 90–95% is needed for elimination. The Ministry of Health and Family Welfare of the Government of India implemented Measles Rubella (MR) campaign in January-February 2017 to increase MR vaccination coverage. This study was carried out to assess the post-campaign coverage of MR vaccination in the urban field practice area of M. R. Medical College. The purpose of this study was to identify factors associated with who is missed in a mass campaign. Objectives: To estimate the coverage of MR vaccination campaign and to determine the reasons for non-immunization of the children. Methodology: Community based cross sectional study was conducted in the urban field practice area of M. R. Medical College, Kalaburagi for a duration of one month during march 2017 and April 2017 among 400 children aged 9 months to 15 completed years using a pre tested, semi structured questionnaire after obtaining informed consent from the study subjects. The data were analyzed using SPSS v 20. Results: Of the 400 children that were studied, the total coverage for MR vaccine was 88.0%. Significant differences in coverage were observed between male (53.41%) and female children (46.59%). The most commonly reported reason for non-vaccination was being child was ill (37.5%) followed by unaware of the campaign (33.33%). Conclusion: In our study, the campaign performance was below the target coverage of 90% set by the Government of India. Enhancing population awareness about rubella disease and its prevention is an important mechanism for increasing understanding of the rationale of the MR vaccine over traditional measles vaccine.

Barriers for measles rubella vaccination campaign in rural area of Jammu: a qualitative study

Background: Measles is a highly contagious virus, spread by contact with an infected person through coughing and sneezing. Like measles, rubella can be prevented with a safe, effective and inexpensive vaccine. This can be delivered as a rubella vaccine alone, or combined with measles vaccine (MR) or with measles and mumps vaccines (MMR). The objectives of the study were to analyze the barriers for acceptance of MR vaccination in the field area of New Type Primary Health Centre (NTPHC) Miran Sahib, one of the NTPHC of CHC R. S. Pura, field practice area of Department of Community Medicine, GMC Jammu.Methods: A qualitative study which consisting of interviews of parents of children both vaccinated as well as unvaccinated as well as teachers and principals of children of various government and private schools, Female Multipurpose Health Worker (FMPHW)s, accredited social health activist (ASHA) workers and Anganwadi workers where the campaign was conducted was also interviewed.Results: The major barrier to acceptance of MR vaccination was wrong message conducted through some social media that it results in deaths of some children in various places, and also the messages spread in some religions like in Muslim community that the Vaccine leads to infertility. But the sensitization meetings with the parents, school staff by the health team prior to vaccination played a major role and results in the vaccine coverage of 95%.Conclusions: Before eliminating MR, there are many barriers which are needed to be addressed.

PENGARUH PROMOSI TENAGA KESEHATAN TERHADAP PENINGKATAN PEMBERIAN IMUNISASI CAMPAK RUBELLA DI PUSKEMAS BANDAR KHALIPAH TAHUN 2019

Measles and rubella can have a negative impact on children's health in Indonesia, so the government has implemented an MR vaccination campaign (MMR VIS - Indonesia, 2012). The MR (Measles Rubella) vaccine provides benefits such as protecting children from disability and death due to complications of pneumonia, diarrhea , brain damage, deafness, blindness and congenital heart disease. There were 83 confirmed cases of CRS in 2015-2016 of which 77% suffered from heart defects, 67.5% suffered from cataracts and 47% suffered from deafness (Ditjen P2P, 2016). The research objective was the Effect of Promotion of Health Workers on the Improvement of Rubella Measles Immunization at the Bandar Khalipah Public Health Center in 2019. This type of research is descriptive analytic with a cross sectional approach with a sample size of 18, it is recommended to carry out promotions. The sampling technique is purposive sampling technique. The research instrument uses leaflet sheets. Univariate analysis using Microsoft Excel. The results showed that the total coverage of rubella measles immunization prior to promotion at the Bandar khalipah health center 2019 was 340 (7.8%) in the "decreased" category and after promotion the total coverage of rubella measles immunization at the Bandar khalipah puskesmas was 367 (8, 6%) are in the “increasing” category. So that there is an effect of promotion of health workers on increasing the provision of rubella measles immunization at the Bandar khalipah public health center in 2019. Conclusion in this study there is an effect of promotion of health workers on increasing rubella measles immunization, so that health workers can use promotion as an effort to support government programs, coverage of immunization rubella measles 95%.

Estimating the immunogenicity of measles-rubella vaccination administered during a mass campaign in Lao People\u2019s Democratic Republic using multi-valent seroprevalence data

Measles and rubella are important causes of morbidity and mortality globally. Despite high coverage reported for measles vaccination, outbreaks continue to occur in some countries. The reasons for these outbreaks are poorly understood. We apply Bayesian methods to multi-valent seroprevalence data for measles and rubella, collected 2 years and 3 months after a mass measles-rubella vaccination campaign in Lao PDR to estimate the immunogenicity and vaccination coverage. When the vaccination coverage was constrained to exceed 95% or 90%, consistent with officially-reported values, the immunogenicity of the measles vaccine component was unexpectedly low (75% (95% CR: 63–82%) and 79% (CR: 70–87%) respectively. The estimated immunogenicity increased after relaxing constraints on the vaccination coverage, with best-fitting values of 83% (95% CR: 73–91%) and 97% (95% CR: 90–100%) for the measles and rubella components respectively, with an estimated coverage of 83% (95% CR: 80–88%). The findings suggest that, if the vaccine coverage was as high as that reported, continuing measles outbreaks in Lao PDR, and potentially elsewhere, may be attributable to suboptimal immunogenicity attained in mass campaigns. Vaccine management in countries with high reported levels of coverage and ongoing measles outbreaks needs to be reviewed if measles elimination targets are to be achieved.

Measles and rubella serosurvey identifies rubella immunity gap in young adults of childbearing age in Zambia: The added value of nesting a serological survey within a post-campaign coverage evaluation survey

BackgroundSerological surveys can potentially complement vaccine coverage surveys, such as post-vaccination campaign coverage evaluation surveys (PCES), by providing direct information on population immunity within and outside the target age range of the mass vaccination campaign. We estimate age-specific population immunity to measles and rubella viruses in Southern Province, Zambia, and assess the value of adding serological data to vaccination coverage estimates by nesting a serological survey within a PCES. MethodsDried blood spots (DBS) from fingerprick blood were collected from all individuals ages nine months or older in households participating in the PCES and tested for measles and rubella virus-specific immunoglobulin G (IgG) by enzyme immunoassay (Siemens Enzygnost, Marburg, Germany). ResultsOverall seroprevalence was 95.5% (95% CI: 92.8, 97.2) for measles virus-specific IgG and 97.7% (95% CI: 96.0, 98.7) for rubella virus-specific IgG. Rubella seroprevalence was 98.4% (95% CI: 95.9, 99.4) among children eligible for the MR vaccination campaign, significantly higher than the reported measles-rubella (MR) vaccination campaign coverage of 89.8% (p = 0.003), and higher than the 91.3% rubella seroprevalence for adolescents and adults 16–30 years of age (p = 0.049). ConclusionSeroprevalence to measles and rubella viruses in children younger than 16 years of age was significantly higher than expected from vaccination coverage estimates, likely reflecting exposure to wild-type viruses and underreporting of vaccination. The serosurvey revealed rubella immunity gaps among women 16–30 years of age, precisely the age group in which protection from rubella is most important to prevent congenital rubella syndrome. Nesting serological surveys within existing surveys can leverage resources and infrastructure while providing complementary information important to immunization programs.

Measles-rubella vaccination campaign: Evaluation of coverage in rural area of Central India

Background: Measles-rubella (MR) vaccination campaign was launched in India in a phasic manner. Maharashtra has launched this in November 2018. Objectives: This study was conducted to evaluate the coverage of MR vaccine in children aged 9–15 years in a rural area of Mohgaon village. Materials and Methods: A community-based cross-sectional study was carried out in the households of the rural village of Mohgaon, with 250 families and 390 eligible children in the age group of 9 months–15 years. Data were collected by the house-to-house visit. Results: Vaccination coverage was found to be 96.41%. Most of the children were in the age group of 6–15 years (74.46%) with no gender bias. Among vaccinated children, 56.25% and 94.27% had thumb mark and vaccination cards, respectively. Less than 5% of the children had minor side effects. Conclusion: Vaccination coverage in a rural area was found to be 96.41%, which is similar to the coverage found other states in an earlier phase.

Drivers and barriers for measles rubella vaccination campaign: A qualitative study.

Background:The measles-rubella (MR) vaccination campaign was launched in Kerala on 3rd October 2017 aiming to eliminate MR by 2020. The drive was carried out in schools, community centers, and medical institutions. The initial phase of the MR campaign met with many controversies that affected its coverage.Objectives:The objectives of the study were to analyze the drivers and barriers for acceptance of MR vaccination in the field area of a primary health center (PHC), which reported a low coverage (62%) during the initial phase of the campaign.Methods:A qualitative study consisting of key informant interviews of parents of vaccinated and unvaccinated children, medical officers of the PHC, Junior Public Health Nurse (JPHN), and Accredited Social Health Activist (ASHA) workers, and the principals of government and private schools where the campaign was conducted was also interviewed.Results:The major barrier to acceptance of MR campaign was the anti-vaccination propaganda in social media. The messages falsely linked fertility issues with the vaccine. The purpose of this campaign was not properly understood by the parents. The campaign was implemented within a short span of time resulting in coordination issues between the stakeholders. However, it was observed that religious affiliations played a major role in reducing coverage. The drivers to acceptance of MR vaccination campaign were the team effort of the healthcare providers who constantly motivated parents to vaccinate their children.Conclusion:Addressing the anti-vaccination propaganda has become the need of the hour. The inclusion of all stakeholders including religious leaders in the planning and implementation of the campaign is essential for its success.

Measles, mumps, and rubella: A cross-sectional study of susceptibility to vaccine-preventable diseases among young people in India

BackgroundGlobal elimination of vaccine preventable diseases, such as measles, mumps and rubella is a priority. Many countries have reported diminishing of antibody titres against these diseases among young population as immunization coverage of adolescents and adults in not monitored. The objective of this study was to determine the susceptibility against measles, mumps and rubella among young adults. MethodsIn this cross-sectional study serological evidence of susceptibility to measles, mumps and rubella was determined by qualitative detection of IgG antibody titres by commercially available enzyme linked florescence assay (VIDAS, bioMerieux) in serum samples young adults. ResultsA total of 335 young individuals (mean age: 20.54 ± 1.37 years) participated voluntarily between May 2017 to September 2018, of which 183 (54.63%) were males. Seroprotection against measles, mumps and rubella were 87.16%, 82.69% and 79.10% respectively. ConclusionSerological surveillance is important to monitor immune status in population. Susceptibility of young adults to measles, mumps, and rubella indicates need for booster vaccination. With the recent launch of measles-rubella vaccination campaign in India, country specific data will be required to plan periodicity of such campaign, which in turn would be based on accumulation of susceptible individuals in a community. Lastly, inclusion of mumps vaccine in the national universal immunization program needs consideration.