This study experimentally investigates the impact of a pair of vertical-axis wind turbines at the leading corners of a tall building on its aerodynamic characteristics. These wind turbines have the potential to serve dual purposes: harnessing wind energy under normal wind conditions and mitigating wind loading of the building under strong wind conditions. The wind tunnel testing results in this study indicate when the tip speed ratio of the turbines is 0.34, with the wind turbines rotating toward downstream, the standard deviation of lift coefficient of the building decreases by 30.9%. Meanwhile, the mean pressure coefficient and the standard deviation of pressure coefficient on both the side face and leeward face of the building also exhibit a certain degree of reduction. The peak value of the power spectral density of lift coefficient of the building is also significantly decreased. This study clearly demonstrates that the wind turbines at the leading corners of tall buildings have the potential to effectively reduce wind loading of the buildings.