Maximum Velocity Values Research Articles

Numerical investigation on the impact of aerodynamic braking plates positioned at streamlined sections on the slipstream and wake flow of the high-speed train based on train-fixed reference frame

This paper studies the aerodynamic characteristics of high-speed trains (HSTs) featuring aerodynamic braking plates installed on the streamlined sections, employing the improved delayed detached eddy simulation (IDDES) method at Re = 5.0 × 105. The precision of the numerical simulation methodology has been validated through reduced-scale wind tunnel experiments. A comparative analysis has been conducted on the characteristics of slipstream, wake flow, and upper flow between the original configuration (OC) and the braking configuration (BC) of the HSTs. The findings reveal that the application of braking plates promotes significant separation phenomena around the HSTs, enhancing the slipstream velocity distribution. In the BC, compared to the OC, the maximum value of the time-averaged slipstream velocity has increased by approximately 134.9% and 76.8% at the trackside and platform positions, respectively. Additionally, the TSI value of the slipstream velocity shows increases of around 100.4% and 210.4% at the trackside and platform positions, respectively. Meanwhile, the turbulence fluctuations within the wake region have been enhanced, with the formation of a longitudinal vortex alongside the railway subgrade, whose core nearly covers the TSI positions. Notably, obvious shifts occur within the upper flow field, which significantly strengthens both flow turbulence and slipstream velocity, potentially influencing components on the upper surface of HSTs, such as the pantograph. The deployment of braking plates contributes to a significant increase in overall vehicle pressure drag, thereby enhancing the train's aerodynamic drag. Relative to the OC, the aerodynamic drag of the HST has increased by approximately 235.4% in the BC.

Clot waveform analysis to differentiate mild, moderate, and severe hemophilia A

Background Clot waveform analysis can be used to evaluate clot formation profiles. This waveform can be obtained from activated partial thromboplastin time (APTT) assays without additional reagents and shows different patterns in hemophilia patients with coagulation factor VIII (F VIII) deficiency or abnormality. Objective To determine the clot wave pattern and its process in clot formation phases (pre-coagulation, coagulation, and post-coagulation) in normal and hemophilia A subjects, analyze for possible correlations between clot wave parameters and F VIII activity, and obtain the pattern of coagulation curves in hemophilia subjects as a step to assess clot waveform analysis as a possible screening tool for hemophilia. Methods In this cross-sectional study, we performed clot wave analysis in 145 adult and pediatric subjects with hemophilia to obtain the clot wave pattern in this condition. Clot wave analysis was also done in 160 subjects with normal hemostasis to obtain reference clot wave parameters. Results In this study, the starting point of coagulation phase in normal subjects was between 30-40 seconds, with a shorter pre-coagulation phase and steeper slope. Hemophilia patients had a longer pre-coagulation phase and flatter slope, especially in severe hemophilia A patients, who had longer and more variable coagulation starting points (P<0.001). The absolute values of maximum coagulation velocity (Min1), maximum coagulation acceleration (Min2), and maximum coagulation deceleration (Max2) of hemophilia A patients were also lower than those of normal hemostasis patients, with lower absolute value seen in severe than in mild-moderate hemophilia A patients. A moderate correlation was found between Min1, Min2, and Max2 with F VIII activity (P<0.001). Conclusion Clot wave analysis may be considered as a method for screening hemophilia patients to distinguish mild-moderate and severe hemophilia A patients in health facilities that lack the ability to perform F VIII assays.

In Vitro Ciclopirox Glucuronidation in Liver Microsomes from Humans and Various Experimental Animals.

Ciclopirox is a widely used antifungal drug, redisposition of which has drawn increasing attentions due to multiple promising activities. The drug undergoes extensive glucuronidation, which acts as a major obstacle in the ongoing novel application and still remains poorly understood. The current study aims to phenotype ciclopirox glucuronidation pathway and as well to decipher the related species differences. Ciclopirox glucuronidation was investigated in liver microsomes from humans (HLM) and various experimental animals. Assays with recombinant uridine diphosphate glucuronosyltransferases (UGTs), enzyme kinetic analyses and selective inhibitors were used to determine the role of individual UGTs in ciclopirox glucuronidation. HLM is highly active in ciclopirox glucuronidation withMichaelis-Menten constant (Km),maximum velocity (Vmax), and intrinsic clearance (CLint)values of 139 μM, 7.89 nmol/min/mg, and 56 μL/min/mg, respectively. UGT1A9 displays by far the highest activity, whereas several other isoforms (UGT1A6, UGT1A7, and UGT1A8) catalyze formation of traced glucuronides. Further kinetic analysis demonstrates that UGT1A9 has a closed Km value (167 μM) to HLM. UGT1A9 selective inhibitor (magnolol) can potently inhibit ciclopirox glucuronidation in HLM with the IC50 value of 0.12 μM. The reaction displays remarkable differences across liver microsomes from mice, rats, cynomolgus monkey, minipig, and beagle dog, with the CLint values in the range of 26-369 μL/min/mg. In addition, ciclopirox glucuronidation activities of experimental animals' liver microsomes were less sensitive to magnolol than that of HLM. Ciclopirox glucuronidation displays remarkable species differences with UGT1A9 as a dominant contributor in humans. It is suggested that the pharmacological or toxicological effects ofciclopirox may be UGT1A9 and species dependent.

Identification and characterization of Lacticaseibacillus rhamnosus HP-B1083-derived β-glucuronidase and its application for baicalin biotransformation

Baicalein, showing higher bioavailability and stronger pharmacological activity, can be obtained via a β-glucuronidase (GUS)-catalyzed transformation of baicalein 7-O-β-D-glucuronide (baicalin). Recently, we have found that the fermentation broth of Lacticaseibacillus rhamnosus HP-B1083 can efficiently convert baicalin to baicalein. In this study, the L. rhamnosus HP-B1083-derived enzyme involved in baicalin biotransformation was identified and characterized. First, the LruidA gene, encoding the responsible enzyme, was cloned and sequenced. Sequence analysis revealed that the deduced enzyme (designated as LrUidA) belonged to the glycosyl hydrolase family 2. The recombinant LrUidA was expressed and purified for characterization. LrUidA had a molecular weight of 70 kDa, with an optimal temperature of 50 °C and pH 4.5. Although LrUidA was susceptible to temperature, it possessed a relative pH stability. Its Michaelis–Menten constant, maximum reaction velocity and catalytic constant values were 9.710 mM, 13.08 mM/min/mg, and 14.95 s−1, respectively. Site-directed mutagenesis experiment results demonstrated that the enzyme reaction uses side chains of E509 and E415 to hydrolyze the glycosidic bond of baicalin and involves three negatively charged residues, E450, D451, and D452, respectively. Surprisingly, biotransformation was performed under optimized reaction conditions by incubating the purified enzyme with 0.1 % baicalin for 4 h, resulting in a considerable conversion ratio of 99 %. Altogether, our findings provide insights into the properties of L. rhamnosus HP-B1083-derived enzyme and expand our understanding regarding using GUS for the industrial production of baicalein.

Polydopamine-functionalized polyethersulfone membrane: A paradigm advancement in the field of α-amylase stability and immobilization

Biocatalytic membranes have great potential in various industrial sectors, with the immobilization of enzymes being a crucial stage. Immobilizing enzymes through covalent bonds is a complex and time-consuming process for large-scale applications. Polydopamine (PDA) offers a more sustainable and eco-friendly alternative for enzyme immobilization. Therefore, surface modification with polydopamine as mussel-inspired antifouling coatings has increased resistance to fouling. In this study, α-amylase enzyme was covalently bound to a bioactive PDA-coated polyethersulfone (PES) membrane surface using cyanuric chloride as a linker. The optimal activity of α-amylase enzyme immobilized on PES/PDA membrane was obtained at temperature and pH of 55°C and 6.5, respectively. The immobilized enzyme can be reused up to five reaction cycles with 55 % retention of initial activity. Besides, it maintained 60 % of its activity after being stored for five weeks at 4°C. Additionally, the immobilized enzyme demonstrated increased Michaelis constant and maximum velocity values during starch hydrolysis. The results of the biofouling experiment of various membranes in a dead-end cell demonstrated that the PES membrane’s water flux increased from 6722.7 Lmh to 7560.2 Lmh after PDA modification. Although α-amylase immobilization reduced the flux to 7458.5 Lmh due to enhanced hydrophilicity, compared to unmodified membrane. The findings of this study demonstrated that the membrane produced through co-deposition exhibited superior hydrophilicity, enhanced coating stability, and strong antifouling properties, positioning it as a promising candidate for industrial applications.

The hemodynamic and geometric characteristics of carotid artery atherosclerotic plaque formation.

Ischemic stroke, which has a high incidence, disability, and mortality rate, is mainly caused by carotid atherosclerotic plaque. The difference in the geometric structures of the carotid arteries inevitably leads to the variability in the local hemodynamics, which plays a key role in the formation of carotid atherosclerosis. At present, the combined mechanisms of hemodynamic and geometric in the formation of carotid atherosclerotic plaque are not clear. Thus, this study characterized the geometric and hemodynamic characteristics of carotid atherosclerotic plaque formation using four-dimensional (4D) flow magnetic resonance imaging (MRI). Ultimately, 122 carotid arteries from 61 patients were examined in this study. According to the presence of plaques at the bifurcation of the carotid artery on cervical vascular ultrasound (US), carotid arteries were placed into a plaque group (N=69) and nonplaque group (N=53). The ratio of the maximum internal carotid artery (ICA) inner diameter to the maximum common carotid artery (CCA) inner diameter (ICA-CCA diameter ratio), bifurcation angle, and tortuosity were measured using neck three-dimensional time-of-flight magnetic resonance angiography (3D TOF-MRA). Meanwhile, 4D flow MRI was used to obtain the following hemodynamic parameters of the carotid arteries: volume flow rate, velocity, wall shear stress (WSS), and pressure gradient (PG). Independent sample t-tests were used to compare carotid artery geometry and hemodynamic changes between the plaque group and nonplaque group. The ICA-CCA diameter ratio between the plaque group and the nonplaque group was not significantly different (P=0.124), while there were significant differences in the bifurcation angle (P=0.005) and tortuosity (P=0.032). The bifurcation angle of the plaque group was greater than that of the nonplaque group (60.70°±20.75° vs. 49.32°±22.90°), and the tortuosity was smaller than that of the nonplaque group (1.07±0.04 vs. 1.09±0.05). There were no significant differences between the two groups in terms of volume flow rate (P=0.351) and the maximum value of velocity (velocitymax) (P=0.388), but the axial, circumferential, and 3D WSS values were all significantly different, including their mean values (all P values <0.001) and the maximum value of 3D WSS (P<0.001), with the mean axial, circumferential, 3D WSS values, along with the maximum 3D WSS value, being lower in the plaque group. The two groups also differed significantly in terms of maximum PG value (P=0.030) and mean PG value (P=0.026), with these values being greater in the nonplaque group than in the plaque group. A large bifurcation angle and a low tortuosity of the carotid artery are geometric risk factors for plaque formation in this area. Low WSS and low PG values are associated with carotid atherosclerotic plaque formation.

Effect of single vanes on turbulent flow

In response to growing environmental and ecological awareness, eco-friendly in-stream structures such as vanes have been implemented in different parts of the world to enhance stream conditions. FLUENT (ANSYS) was used to perform three-dimensional large eddy simulation to investigate the effect of the vanes permeability rate on flow characteristics. To evaluate the numerical model accuracy, numerical and experimental free surface profiles compared. It is observed that simulated free surface profiles agree reasonably well with measured values. The effect of different permeability rates is obvious in the flow characteristics such as depth-averaged velocity distribution, tip velocity variations, formation of the secondary flows in the flow field, turbulent kinetic energy, and mean kinetic energy contours. On average, maximum velocity values in the flow field is 1,54 times the approach velocity. Tip velocity decreases up to 30,6 % for the 70,0 % permeable vane. Maximum turbulent kinetic energy and mean kinetic energy for the 70,0 % permeable vane decrease up to 58,0 % and 43,3 %, respectively. Generally significant velocity and flow pattern variations around the impermeable vane can be attributed to the local effect of the vane structure and channel cross sectional constriction in comparison to the permeable vanes.

Interfacial heat transfer and melt-front evolution at a Fractal Cantor structured interface under various PCM melting conditions

With the aim to investigate heat transfer characteristics of PCM on micro-textured hot surface, this study numerically investigates the heat transfer process of PCM at fractal Cantor structured surfaces using the total enthalpy-based lattice Boltzmann method, which is partly validated by experimental testing. The thermal slip length and liquid velocity distribution are assessed as evaluation criteria. Results show that Fractal Cantor structure can significantly stimulate localized thermal convection, thereby reducing the average thermal slip length from 0.3 mm to approximately 0.14 mm. When the Fourier number exceeds 0.1, both thermal conduction and convection should be considered within the melted layer. With the fractal level increasing, a more uniform melt-front evolution can be observed, consequently, minimizing the total melting time by 500 s with the fractal level of 3. Elevating Ste and gravity can significantly increase the flow rate of liquid PCM by augmenting superheat degree and buoyancy effect, thereby enhancing convective heat transfer strength and reducing thermal slip length. According to the orthogonal design, though the fractal level demonstrates minimal range values for both maximum velocity and Rayleigh number, it elevates the sensitivity to the variation of boundary conditions. Ste yields the most significant enhancement in heat transfer performance.

Investigating Serotonin Dynamics and Simulating Effects of Antidepressants Using Variation in Enzyme Expression

Serotonin plays a crucial role in the symptoms of depression, and understanding its dynamics in the brain is of the utmost importance in determining how to mitigate the effects of depression. We investigate a mathematical model presented by Best et al. (2020) that examines serotonin dynamics in the substantia nigra pars reticulata. By incorporating experimental data and a stochastic systems population model, several biological mechanisms and observations are further understood. A populations model is utilized to account for enzymatic expression level variation from 75% to 125% of their base values. When generating the population model, uniform distributions are assumed when simulating maximum velocity values, which correspond to enzyme expression levels. We investigate this assumption and show that it is reasonably insensitive; that is, changes in the distributions used to generate these values do not significantly change the results of the model. We also use the model to simulate the effects of monoamine oxidase inhibitors (MAOIs), one of the first treatments discovered for depression. We then use similar methods to simulate the effects of selective serotonin reuptake inhibitors (SSRIs), the most common antidepressant used today. We demonstrate that low enzyme expression levels of tryptophan hydroxylase and neutral amino acid transporter are most associated with low extracellular serotonin values at the steady state, indicating that these two enzymes may play key roles in predicting which patients may or may not respond to SSRI treatment.

МАТЕМАТИЧЕСКОЕ ОПИСАНИЕ ДИНАМИКИ ЦЕНТРОБЕЖНОГО ДВУХФАЗНОГО ПОТОКА В ПОМОЛЬНОЙ КАМЕРЕ ДЕЗИНТЕГРАТОРА

Rational control of equipment operating modes in the production of building materials is possible only in the case of a mathematical description of various technological processes. The sequence of calculation methods for determining the design and technological parameters of grinding equipment makes it possible to numerically present the results of calculations of rational operating modes of the equipment. The study presents a mathematical description of the dynamics of a two-phase flow inside the grinding chamber of a disintegrator, with the help of which it is possible to determine the speed characteristics of its operating modes for materials with different physical and mechanical properties. The nature of the change in the tangential components of the velocities of the two-phase flow has been established: the range of the current radius of the grinding chamber Ri has been determined, at which the radial components of the velocities of the carrier flow and particles of the ground material continue to increase. As a result of mathematical modeling, it was confirmed that with an increase in the concentration of dust particles in the increasing volume of the grinding chamber, the value of the tangential component of the velocity of a dynamic two-phase flow decreases in relation to the maximum parameters at Ri = 0.15 m by an average of 15.5%. It has been determined that the maximum velocity values for the tangential component are in the limit of Ri = 0.1-0.15 m and are 131 m/s for air, and 127.5 m/s for an average suspended particle with dsr = 40 μm. In the process of developing a mathematical description, it was established that in the range Ri = 0.15 - 0.3 m the increase in the radial components of the velocities of the air carrier medium and the weighted average particle flow is about 14.5%, which, in turn, indicates an increase in the kinetic energy of the crushed particles during the movement of a dynamic two-phase flow from the center to the periphery of the grinding chamber of the disintegrator.

Exact solution of electroosmotic flow of the second grade fluid in a circular microchannel driving by an AC electric field

Microfluidics development has led to increased attention on electroosmotic flow in biotechnology and lab-on-a-chip technologies. In this particular investigation, an analytical solution is derived for the electroosmotic flow of a second grade fluid in a circular microchannel driven by an AC electric field. The derivation is based on the Debye–Hückel linear approximation. Analytical expressions for the electric potential and velocity profile are obtained by solving the linearized Poisson–Boltzmann equation and the Navier–Stokes equation. Numerical results are presented to examine the influence of various factors on the velocity profile and volumetric flow rate. Specifically, the effects of the retardation time λ, the frequency of the applied external electric field ω, and the electrokinetic width K are analyzed. The results demonstrate that a more considerable retardation time λ leads to reduced fluctuations in the velocity profile and a smaller maximum velocity value. Conversely, smaller values of λ or ω result in larger amplitudes of the volumetric flow rate.

Numerical study on thermal hydraulics characteristics during steam submerged jet condensation from rectangular CD nozzle

The phenomenon of steam-water direct contact condensation (DCC) has significant importance in nuclear industry due to its rapid and efficient heat and mass transfer rates. In this numerical study, three dimensional simulations of steam submerged jet condensation from rectangular converging-diverging (CD) nozzle into subcooled water has been investigated. The steam condensation phenomenon has been captured from thermal phase change model as user defined function (UDF) in ANSYS Fluent software. The computational results were validated using experimental results as well as previously published numerical study. The effects of steam pressure and water temperature on distributions of various thermal hydraulics parameters including velocity, pressure, temperature, heat and mass transfer characteristics have been studied. The steam pressure and water temperature have been kept in the range of 200–500 kPa and 20–60 °C, respectively. The maximum value of jet velocity and heat transfer coefficient have been found as 803 m/s and 2.73 MW/m2K respectively. The peak velocity value increases with steam pressure. After maximum expansion point, the velocity profile curve is shifted downstream with steam pressure. The axial pressure distribution first decreases and then increases from expansion-compression waves. The axial temperature profile followed the similar trend as observed for axial steam pressure distribution. At constant steam pressure, the maximum rate of heat transfer coefficient decreases with the increase in water temperature. The maximum mass transfer rate under prescribed flow conditions has been found as 2789.8 kg/m3s. The peak mass transfer rate decreases with steam pressure and water temperature. The peak rates for heat and mass transfer have been observed in the nearby vicinity of nozzle exit location.

Study on the Driving Risk Reduction in the Mountain Highway Tunnel Group under the Perspective of Visual Load

More highway built in the mountains in recent years, the driving risk in the tunnel group is becoming a new issue. This paper analyzed the driving risk in the mountain highway tunnel group from the perspective of visual load. Based on vehicle test in the Pengshui‐Xiantang tunnel group in China, the evolution characteristics of MTPA were quantitatively analyzed, and the random forest model was constructed to discuss the effect factors of the maximum transient velocity value of the pupil area (MTPA) in different sections. The results are as follows: (1) The MTPA frequently presents a tendency of steep rise and fall in the tunnel group. MTPA in the second tunnel is significantly higher than the first tunnel. (2) The mountain tunnel group can be divided into nine sections; the velocity, design luminance, measured luminance, and location have different effects on MTPA in each section. Due to the complex terrain conditions, the location has a more significant impact on MTPA in the second tunnel. (3) The first tunnel entrance, the first tunnel exit to the second tunnel entrance, and the second tunnel exit are the areas with more significant pressure on drivers in the tunnel group. The visual load of drivers in the exit section of the last tunnel is the greatest. The driving risk reduction recommendations include improving the transition lighting design of the second tunnel, clarifying the tunnel group identification, and adding safety features at the tunnel connection section, in order to clarify the driver’s expectations and reduce the fear of the unknown mountain environment.

Investigations of the Mass Transfer and Flow Field Disturbance Regulation of the Gas–Liquid–Solid Flow of Hydropower Stations

With the continuous depletion of fossil fuels, all countries attach importance to clean and sustainable development. The real-time state monitoring of multiphase flows is vital for enhancing hydropower station energy conversion. However, the material mass transfer mechanism and flow field disturbance regulation strategy faces significant challenges. To solve these problems, a computational fluid mechanics and discrete element method (CFD-DEM) coupling modeling and solution method based on a particle porosity model was proposed, and the mass transfer mechanism of gas–liquid–solid mixing flows was obtained under dynamic whirl intensity regulations. Combined with the user-defined function (UDF), the interphase forces and void ratios of fluids and particles were calculated to obtain the material mass transfer laws under dynamic disturbance regulations. The evolution characteristics of the particle flow pattern were tracked during the material mixing process. The results show that the mixed flow field had a high material transport efficiency under intensive whirl regulation, especially for the particle aggregation in the center of the reaction vessel. The maximum peak velocity and energy values of the particle transport process were 3.30 m/s and 0.27 × 10−3 m2·s−2. The higher whirl regulation improved the material transport process and conveying efficiency and enhanced the particle mixing effect in the reaction space. Relevant research results can provide theoretical references for material mass transfer mechanisms, dynamic regulation strategies, and particle flow pattern identifications and can also provide technical support for hydropower energy conversion.

Agricultural wastes: a new promising source for phenylalanine ammonia-lyase as anticancer agent.

The present study aims to investigate the physicochemical characteristics of phenylalanine ammonia-lyase (PAL) extracted from agricultural waste and its potential use as an anticancer agent in comparison to microbial PAL. We extracted and partially purified PAL from agricultural waste sources. We assessed the temperature and pH range of PAL and determined enzyme kinetics parameters including Michaelis constants (Km), maximum velocity (Vmax), and specificity constant values (Vmax/Km). Additionally, we examined the effects of different storage temperatures on PAL activity. In our analysis, we compared the efficacy of agricultural waste-derived PAL with PAL from Rhodotorula glutinis. The results demonstrated that PAL extracted from agricultural waste exhibited significantly higher specific activity (Vmax/Km) compared to its microbial counterpart. The agricultural waste-derived PAL displayed a stronger affinity for phenylalanine, as indicated by a lower Km value than the microbial PAL did. Furthermore, PAL from agricultural waste maintained activity across a broader temperature and pH range (15-75°C, pH 5-11), in contrast to microbial PAL (20-60°C, pH 5.5-10). Importantly, the PAL derived from agricultural waste exhibited superior stability, retaining over 90% of its activity after 6months of storage at room temperature (25°C), whereas microbial PAL lost more than 70% of its activity under similar storage conditions. In anticancer experiments against various cancer cell lines, agricultural waste-derived PAL demonstrated greater anticancer activity compared to microbial PAL. These findings suggest that PAL sourced from agricultural waste has the potential to be a safe and effective natural anticancer agent.

Effects of topological and non-topological edge states on information propagation and scrambling in a Floquet spin chain

The action of any local operator on a quantum system propagates through the system carrying the information of the operator. This is usually studied via the out-of-time-order correlator (OTOC). We numerically study the information propagation from one end of a periodically driven spin-1/2 XY chain with open boundary conditions using the Floquet infinite-temperature OTOC. We calculate the OTOC for two different spin operators, σ x and σ z . For sinusoidal driving, the model can be shown to host different types of edge states, namely, topological (Majorana) edge states and non-topological edge states. We observe a localization of information at the edge for both σ z and σ x OTOCs whenever edge states are present. In addition, in the case of non-topological edge states, we see oscillations of the OTOC in time near the edge, the oscillation period being inversely proportional to the gap between the Floquet eigenvalues of the edge states. We provide an analytical understanding of these effects due to the edge states. It was known earlier that the OTOC for the spin operator which is local in terms of Jordan–Wigner fermions (σ z ) shows no signature of information scrambling inside the light cone of propagation, while the OTOC for the spin operator which is non-local in terms of Jordan–Wigner fermions (σ x ) shows signatures of scrambling. We report a remarkable ‘unscrambling effect’ in the σ x OTOC after reflections from the ends of the system. Finally, we demonstrate that the information propagates into the system mainly via the bulk states with the maximum value of the group velocity, and we show how this velocity is controlled by the driving frequency and amplitude.

Vortex Dynamics in Superconducting MoN Strip with a Side Cut

Transport characteristics of superconducting MoN strips with a single side cut near one of the superconductor edges in zero and weak magnetic fields are studied experimentally and theoretically. The presence of the cut makes it possible to observe regimes with one and several simultaneously moving Abrikosov vortices, the number of which is controlled by the value of the applied current. A change in the number of vortices is accompanied with the emergence of a “kink” on the current–voltage characteristic, which can be clearly distinguished in the dependence of the differential resistance on the current. This makes it possible to find average velocityv¯of vortices (including a single vortex) and the current/voltage ranges with the known number of moving vortices. The vortex velocity determined in this way for our superconducting strips turns out to be weakly depending on the current and is close to maximal valuev¯max≈ 3 km/s, for which a superconductor transition to the normal state occurs. The maximal velocity value is comparable with the known values for superconductors of types Nb, NbN as well as, and YBCO, but is several times smaller than for superconductors of types MoSi, NbC, and Pb. The fact that difference in the maximal velocities of vortices is associated with different times of variation of the superconducting order parameter magnitude in different superconducting materials is considered.

Research on Stability Control Algorithm of Distributed Drive Bus under High-Speed Conditions

Aiming at the instability problem of a four-wheel independent drive electric bus under high-speed conditions, this paper first designs a vehicle yaw stability controller based on a linear two-degree-of-freedom model and a linear quadratic programming (LQR) algorithm. A vehicle roll stability controller is then designed based on a linear three-degree-of-freedom model and a model predictive control algorithm (MPC). Moreover, a coordinated control rule based on the lateral load transfer rate (LTR) is designed for the coupled problem of yaw and roll dynamics. Finally, the effectiveness of the proposed control algorithm is verified by simulation. The obtained results show that when the vehicle is running at a high speed of 90 km/h, the stability control algorithm can control the yaw rate tracking error within 0.05 rad/s. In addition, the control algorithm can reduce the maximum amplitude of the side slip angle, the maximum value of the roll angle, the maximum value of the roll angular velocity, and the amplitude of the lateral acceleration by more than 96%, 81.1%, 65.0%, and 11.1%, respectively.

Sustainable Immobilization of β-Glucosidase onto Silver Ions and AgNPs-Loaded Acrylic Fabric with Enhanced Stability and Reusability.

Modified polymer design has attracted significant attention for enzyme immobilization, offering promising applications. In this study, amine-terminated polymers were synthesized by incorporating functional groups into polyacrylonitrile using hexamethylenediamine. This work highlights the successful enzyme immobilization strategy using modified polymers, offering improved stability and expanded operational conditions for potential biotechnological applications. The resulting amino groups were utilized to capture silver ions, which were subsequently converted to silver nanoparticles (AgNPs). The obtained materials, AgNPs@TA-HMDA (acrylic textiles coated silver nanoparticles AgNPs) and Ag(I)@TA-HMDA (acrylic textiles coated with Ag ion) were employed as supports for β-glucosidase enzyme immobilization. The highest immobilization yields (IY%) were achieved with AgNPs@TA-HMDA at 92%, followed by Ag(I)@TA-HMDA at 79.8%, resulting in activity yields (AY%) of 81% and 73%, respectively. Characterization techniques such as FTIR, FE-SEM, EDX, TG/DTG, DSC, and zeta potential were employed to investigate the structural composition, surface morphologies, elemental composition, thermal properties, and surface charge of the support materials. After 15 reuses, the preservation percentages decreased to 76% for AgNPs@TA-HMDA/β-Glu and 65% for Ag(I)@TA-HMDA/β-Glu. Storage stability revealed that the decrease in activity for the immobilized enzymes was smaller than the free enzyme. The optimal pH for the immobilized enzymes was broader (pH 5.5 to 6.5) compared to the free enzyme (pH 5.0), and the optimal temperature for the immobilized enzymes was 60 °C, slightly higher than the free enzyme's optimal temperature of 50 °C. The kinetic analysis showed a slight increase in Michaelis constant (Km) values for the immobilized enzymes and a decrease in maximum velocity (Vmax), turnover number (Kcat), and specificity constant (Kcat/Km) values compared to the free enzyme. Through extensive characterization, we gained valuable insights into the structural composition and properties of the modified polymer supports. This research significantly contributes to the development of efficient biotechnological processes by advancing the field of enzyme immobilization and offering valuable knowledge for its potential applications.

Research on the impact of air-blowing on aerodynamic drag reduction and wake characteristics of a high-speed maglev train

The maglev train fills the speed gap between ground transportation and airplanes. However, the increasing train speed results in greater energy losses due to increased aerodynamic drag, impeding the green and sustainable development of high-speed railways. This study employs the numerical simulation method to explore the effects of installing air-blowing slots on the surface of the TR08 maglev train's tail car and blowing air along three different directions at two different speeds on drag reduction and the characteristics of the wake flow field. Among them, only blowing air along the streamwise direction at speeds of 12 m/s (X12) and 24 m/s (X24) shows drag reduction effects of 2.06% and 6.53%, respectively. However, considering the energy efficiency, only X12 achieves a net energy saving of 58.96%, while the energy consumption by blowing air and saving by reducing drag in X24 are roughly balanced. Air-blowing reduces the aerodynamic lift of the tail car (Cl), with blowing air along the perpendicular direction at 24 m/s (Z24) reducing the Cl by 99.57%. Additionally, Z24 reduces the maximum velocity value of the train-induced air flow (Usmax¯) by 61.91%. The research findings provide new insight and data support for the development of blowing/suction drag reduction techniques.