Maximal Exercise Intensity Research Articles

Incremental exercise, plasma concentrations of catecholamines, reaction time, and motor time during performance of a noncompatible choice response time task.

The primary purpose was to examine the effect of incremental exercise on a noncompatible response time task. Participants (N=9) undertook a 4-choice noncompatible response time task under 3 conditions, following rest and during exercise at 70% and 100% of their maximum power output. Reaction and movement times were the dependent variables. Maximum power output had been previously established on an incremental test to exhaustion. A repeated-measures multivariate analysis of variance yielded a significant effect of exercise intensity on the task, observation of the separate univariate repeated-measures analyses of variance showed that only movement time was significantly affected. Post hoc Tukey tests indicated movement time during maximal intensity exercise was significantly faster than in the other two conditions. The secondary purpose of the study was to assess whether increases in plasma concentrations of adrenaline and nor-adrenaline during exercise and power output would act as predictor variables of reaction and movement times during exercise. Catecholamine concentrations were based on venous blood samples taken during the maximum power output test. None of the variables were significant predictors of reaction time. Only power output was a significant predictor of movement time (R2 = .24). There was little support for the notion that peripheral concentrations of catecholamines directly induce a central nervous system response.

Body position affects performance in untrained cyclists

Objective: To compare cardiovascular and ventilatory variables in upright versus aero cycle ergometry at submaximal and maximal exercise intensities in untrained cyclists. Method: Ten physically active men (mean (SD) age...

AEROPOSITION AFFECTS PERFORMANCE IN UNTRAINED CYCLISTS

Cycling performance is influenced by refining either the human performance or via innovations in equipment. The aerobar is an extension attached to handlebars that places the cyclist in a lowered position. Although research has shown that aerobars reduce wind resistance during cycling, there is conflicting evidence as to the physiological response to adopting the aero position. PURPOSE To compare cardiovascular and ventilatory parameters in upright (U) versus aero (A) cycle ergometry at submaximal and maximal exercise intensities in untrained cyclists. METHODS Ten physically active males (mean age 19.1±1.10 years) who were unfamiliar with aerobars underwent maximal exercise testing and steady state cycling at 50, 100 and 150 watts. RESULTS In the upright position, participants had significantly greater maxima (mean (95%CI):upright;aero) for VO2, [52.85ml·kg-1·min-1 (49.19–56.49); 50.25ml·kg-1·min-1 (47.22–53.27)], ventilation, [130.11 (1-min-1) (119.77–140.45); 116.64(1-min-1) (107.24–126.04)], heart rate [195bpm (192–199); 191bpm (188–194)], and workload max [280watts (262–298); 265watts (246–284)] in the upright position. During steady state cycling at the three workloads, VO2(ml·kg-1·min-1) and gross mechanical efficiency were enhanced in the upright position. CONCLUSION In untrained subjects undertaking maximal effort, the upright position permits greater VO2, ventilation, heart rate and workload maxima. Further, during steady state exercise cycling may be less costly in the upright position. For this reason, untrained cyclists need to weigh body position effects against the well-known aerodynamic advantages of the aero position.

Effects of fatigue on the torque-velocity relation in muscle

Background: The extent to which fatigue is related to the velocity of shortening is still not fully understood. Objectives: To examine the effects of fatigue induced by maximal intensity exercise...

Maximal Intensity Exercise Performance of Young People

LANGUAGE NOTE | Document text in English; abstract also in Chinese.Exercise data show that young people's capability to perform exercise tasks of a maximal intensity lasting between one and 90 seconds, are lower than that of adults. In general, the maximal intensity exercise performance of young people improves with age and level of biological maturity but further research that involve larger samples of boys and girls, over the entire maturity range are needed to supplement the sparse database. Data of girls are notably lacking. More research is needed to identify the specific development stage (s) where young people acquire the adult levels of maximal intensity exercise performance. Longitudinal studies, encompassing the entire maturity range (i.e. Tanner stages one to five) of young people are needed to clarify the evolution and stability of maximal intensity exercise performance with age and maturation. Multiple bouts of maximal intensity exercise can shed light on the fatigue and power recovery profile of young people and research in this area is deserving of encouragement.研究資料顯示，青年人進行最大強度運動的持續時間較成年人短，約為1 - 90秒。一般認為，隨著年齡增長及身體各器官系統發育成熟，青年人最大運動能力提高，但這有待於大量的實驗數據加以驗證，包括不同年齡階段成熟度的資料。在這方面，女性的資料尤為缺乏。有關青年人在何一生長發育階段可達到成年人的最大運動能力的水平，這是一個需要進一步研究證實的課題。對於青年人的最大強度運動能力隨著年齡的增長及生長發育而發展以至穩定的過程，進行縱向調查是十分必要的，而以反覆多次最大強度運動的形式觀察青年人的疲勞與恢復過程是值得重視與推荐的。

Effect of exercise on plasma ferritin concentrations: implications for the measurement of iron status.

Iron is of key importance for aerobic metabolism, and natural feeds of the horse are fairly rich sources of iron. Accordingly, the known incidence of iron deficiency anaemia is apparently rare in performance horses; despite this, iron deficiency in performance horses continues to be of concern to trainers and veterinarians. Effects of exercise on plasma ferritin concentrations were therefore studied in Standardbreds, Finnhorses and half-bred riding horses. Blood samples were taken after a moderate exercise test on a racetrack, a competition exercise test on a treadmill and a race. Even moderate exercise caused an increase in plasma ferritin concentration, with the increase being greater as the intensity and duration of exercise increased. Return to the basal level was slower after maximal-intensity exercise than after moderate exercise. In conclusion, although ferritin is a useful marker of low iron stores, samples should be taken only after at least 2 days rest following strenuous exercise.

Use of Muscle Oxygen Saturation in Determining Maximal Steady State Exercise Intensity.

Use of Muscle Oxygen Saturation in Determining Maximal Steady State Exercise Intensity.

Short-term muscle power during growth and maturation.

During growth and maturation, the study of very brief high-intensity exercise has not received the same attention from researchers as, for instance, aerobic function. In anaerobic tasks or sports events such as sprint cycling, jumping or running, the children's performance is distinctly lower than that of adults. This partly reflects children's lesser ability to generate mechanical energy from chemical energy sources during short-term intensive activity. For many years, various attempts have been made to quantify the anaerobic energy yield in maximal-intensity exercise, but many assumptions have had to be made with respect to mechanical efficiency, lactate turnover, dilution space for lactate, and so on. During childhood and adolescence, direct measurements of the rate or capacity of anaerobic pathways for energy turnover presents several ethical and methodological difficulties. Thus, rather than measure energy supply, paediatric exercise scientists have concentrated on measuring short-term muscle power (STMP) by means of standardised tests. Previously, investigators have used various protocols such as short-term cycling power tests, vertical jump tests or running tests. Cycling ergometer tests are the most common. There is, however, no ideal test, and so it is important to acknowledge the limitations of each test. Progress has been made in assessing instantaneous cycling STMP from a single exercise bout. Several investigators have reported STMP increases with age and have suggested that late pubertal period may accentuate anaerobic glycolysis. Mass-related STMP was shown to increase dramatically during childhood and adolescence, whereas the corresponding increase in peak blood lactate was considerably lower. The latter results support the hypothesis that the difference observed between children and adolescents during STMP testing is more related to neuromuscular factors, hormonal factors and improved motor coordination, rather than being an indicator of reduced lactate-producing glycolysis mechanism. Evidence suggesting a causal link between the ability to generate lactate during exercise and sexual maturation is weak. Despite the majority of research being focused on short-term power output, the study of anaerobic function warrants more investigation. Spectacular progress is being made at the moment in the development of molecular biology tools that can be used in, for example, the genetic dissection of human performance phenotypes. Noninvasive power tools like magnetic resonance imaging and magnetic resonance spectroscopy are presently used to determine possible differences in phosphorus compounds between fast and slow fibre types. Undoubtedly these tools will lead to more information in the near future regarding STMP capabilities of the growing child.

The rate of phosphocreatine hydrolysis and resynthesis in exercising muscle in humans using 31P-MRS.

Time-resolved 31-phosphorus nuclear magnetic resonance spectroscopy (31P-MRS) of the biceps femoris muscles was performed during exercise and recovery in six healthy sedentary male subjects (maximal oxygen uptake; 46.6 +/- 1.7 (SEM) ml.kg-1.min-1), 5 male sprinters (56.2 +/- 2.5), and 5 male long-distance runners (73.6 +/- 2.2). Each performed 4 min of knee flexion exercises at absolute values of 1.63 W and 4.90 W, followed by 5 min of recovery in a prone position in a 2.1 T superconducting magnet with a 67 cm bore. 31P-MRS spectra were recorded every 12.8 s during the rest-exercise-recovery sequence. Computer-aided contour analysis and pixel imaging of phosphocreatine peaks (PCr) and inorganic phosphate (Pi) were performed. The work loads in the present study were selected as mild exercise (1.63 W) and heavy exercise (4.90 W), corresponding to 18-23% and 54-70% of maximal exercise intensity. Long-distance runners showed a significantly smaller decrement in PCr and less acidification at a given exercise intensity compared to those shown by sedentary subjects. The transient responses of PCr and Pi during recovery were characterized by first-order kinetics. After exercise, the recovery rates of PCr and Pi were significantly faster in long-distance runners than in sedentary subjects (P < 0.05). Since it is postulated that PCr resynthesis is controlled by aerobic metabolism and mitochondrial creatine kinase, it is suggested that the faster PCr and Pi recovery rates and decreased acidification seen in long-distance runners during and after exercise might be attributed to their greater capacity for aerobic metabolism.

Effect of dehydration on gastrointestinal function at rest and during exercise in humans.

Dehydration leads to the aggravation of gastrointestinal (GI) complaints during exercise. The aim of this study was to examine the effect of dehydration on various GI parameters during strenuous exercise. Ten healthy well-trained men were investigated in dehydrated and in euhydrated conditions. Dehydration took place before the experiments using a dehydration regimen in a sauna leading to a 3% loss of body mass. Each experiment consisted of 1 h pre-exercise rest, 1.5 h cycling at 70% maximal exercise intensity, and 3.5 h post-exercise rest. During cycling, liquid gastric emptying (GE), orocaecal transit time (OCTT) and intestinal permeability and glucose absorption were measured. The GI-symptoms were scored using a questionnaire. Body temperature, plasma volume and vasopressin were measured before and after cycling. The GE was significantly slower during dehydration [median time to peak 13C enrichment in the breath sample (13C-TTP) 23.6 min, range 13.7-50.0 min, P = 0.02] than in the control situation (median 13C-TTP 17.1 min, range 9.8-38.4 min). The OCTT was unchanged (median 173 min, range 98-263 min compared to median 128 min, range 98-195 min, P = 0.18). Dehydration did not change intestinal permeability, glucose absorption, plasma volume, rectal temperature or plasma vasopressin concentration. In the dehydration experiment, exercise induced a significant increase in nausea (P = 0.01) and epigastric cramps (P = 0.05), in contrast to the control situation. In both experiments, exercise led to a significant increase in rectal temperature and plasma vasopressin concentration, and a significant decrease in plasma volume. The increase in plasma vasopressin concentration was significantly higher in the dehydration experiment (P = 0.015). No significant differences in either the post-exercise rectal temperatures or in plasma volumes was observed. The difference in GE between the two experiments was significantly correlated with the difference in nausea score (r = 0.87, P = 0.002). We concluded that dehydration leads to a delayed GE but not to differences in OCTT, intestinal permeability or glucose uptake during intense cycling. The delay in GE is significantly associated with an increase in exercise-induced nausea.

Plasma lactate concentration and muscle blood flow during dynamic exercise with negative-pressure breathing.

This study assessed the hypothesis that increasing cardiac filling pressure (CFP) would enhance contracting muscle blood flow (MBF) by stretching cardiopulmonary baroreceptors and attenuate the increase in plasma lactate concentration ([Lac(-)](p)) during dynamic exercise. Continuous negative-pressure breathing (CNPB) (-15 cmH(2)O) was used to increase the CFP by accelerating the venous return to the heart. In the first series of experiments, 10 men performed a graded exercise seated on a cycle ergometer with (N1) and without CNPB (C1). The increase in [Lac(-)](p) for N1 was attenuated at 60%, 90%, and 100% of maximal exercise intensity compared with that in C1 (P < 0.001). Also, the increases in mean arterial pressure (MAP) and plasma catecholamine concentrations were attenuated in N1 compared with those in C1 throughout the graded exercise (P < 0.05). However, heart rate and pulse pressure were not significantly influenced by CNPB. Second, we studied the impact of CNPB on forearm MBF during a rhythmic handgrip exercise in 5 of the 10 subjects. Forearm MBF was measured immediately after cessation of the exercise by venous occlusion plethysmography at rest, 30%, 50%, and 70% of maximal work load (WL(max)) with (N2) and without CNPB (C2). Forearm MBF and vascular conductance for both trials increased with the increase in intensity, but forearm skin blood flow measured by laser-Doppler flowmetry remained unchanged. MBF and vascular conductance in N2, however, increased more than in C2 at every intensity (P < 0.01) except for MBF at 70% WL(max), whereas the increase in MAP for N2 was attenuated compared with that in C2 (P < 0.05). Thus augmented active muscle vasodilation occurred in N2 with a lower increase in MAP compared with that in C2. These findings suggest that the stretch of intrathoracic baroreceptors, such as cardiopulmonary mechanoreceptors, by CNPB increased MBF by suppressing sympathetic nerve activity. The attenuation of the increase in [Lac(-)](p) might be caused, at least partially, by the increased MBF.

Performance of a psychomotor skill following rest, exercise at the plasma epinephrine threshold and maximal intensity exercise.

The purpose of this study was to examine the effect of exercising at the epinephrine threshold and at Maximum Power Output on the performance of a skill that requires both decision-making and motor performance. Participants (N=12) undertook an incremental test to exhaustion from which their epinephrine threshold and Maximum Power Output were calculated. They were then examined on a soccer skill test following rest and exercise that was previously determined to elicit their epi nephrine threshold and Maximum Power Output. The soccer test examined the participants' speed and accuracy of response. Speed of response was measured by voice reaction time and whole body reaction time. No significant effects of exercise were shown for any of the variables. The need for further research using more complex skill tests and the use of discontinuous exercise protocols, rather than continuous ones, is recommended.

Maximising the clinical use of exercise gaseous exchange testing in children with repaired cyanotic congenital heart defects: the development of an appropriate test strategy.

Implicit in deciding upon an exercise test strategy to elucidate cardiopulmonary function in children with congenital heart disease are appropriate application of gas exchange techniques and the significance of the data collected to the specific congenital heart disorder. Post-operative cardiopulmonary responses to exercise in cyanotic disorders are complex and, despite a large body of extant literature in paediatric patients, there has been much difficulty in achieving quality and consistency of data. Maximal oxygen uptake is widely recognised as the best single indicator of cardiopulmonary function and has therefore been the focus of most clinical exercise tests in children. Many children with various heart anomalies are able to exercise to maximum without adverse symptoms, and it is essential that test termination is based on the same criteria for these children. Choosing appropriate, valid indicators of maximum in children with congenital heart disease is beset by difficulties. Such maximal intensity exercise testing procedures have been challenged on the grounds that they do not give a good indication of cardiopulmonary function that is relevant to real life situations. Furthermore, they are prone to much interindividual variability and error in the definition of maximal exertion. Alternative strategies have been proposed which focus upon dynamic submaximal and kinetic cardiopulmonary responses, which are thought to be less dependent on maximal voluntary effort and more suited to the daily activity patterns of children. These methods are also not without problems. Variability in anaerobic threshold measurements and controversy regarding its physiological meaning have been debated. It is recommended that an appropriate cardiopulmonary exercise gas exchange test strategy, which provides clinically useful information for children with cyanotic congenital heart disease, should include both maximal and submaximal data. The inclusion of oxygen uptake kinetics and ventilatory data are encouraged, since they may allow the distinction between a pulmonary, cardiovascular or inactivity related exercise limitation.

Pulmonary capillary pressure in horses undergoing alteration of pleural pressure by imposition of various upper airway resistive loads.

We hypothesized that changes in pleural pressure induced by resistive breathing would affect transmural pulmonary artery, pulmonary capillary, and pulmonary wedge pressures. Seven horses were assigned to exercise with each of 4 upper respiratory resistive loads in random order at intervals of at least 2 days: 1) control--no added resistive loads; 2) inspiratory resistive load (Iobst)--left laryngeal hemiplegia; 3) expiratory resistive load (Eobst)--one-way valve in the right nostril; and 4) combined inspiratory and expiratory resistive loads (CIEobst)--left nostril occlusion. On each occasion, the horses performed an incremental exercise protocol consisting of exercise episodes of 3 min duration at 75, 90, and 100% of maximal heart rate (HRmax). Pulmonary artery and oesophageal pressures were recorded continuously. Subsequent analysis was carried out on the pulmonary arterial pressure signal with the oesophageal pressure signal subtracted, hence the pulmonary vascular pressures in this paper approximate transmural pressures. Pulmonary vascular pressures, heart rate, and arterial blood gas tensions were measured at each level of exercise. Pulmonary capillary and pulmonary wedge pressures were determined from the pulmonary artery waveform after dynamic occlusion of a branch of the pulmonary artery. During exercise, peak expiratory oesophageal pressure was more positive in horses with Eobst and CIEobst (adjusted means = 43, and 39 mmHg, respectively) compared with control (adjusted mean = 23 mmHg) (P = 0.0001). Peak inspiratory oesophageal pressure was more negative in horses at exercise with Iobst and CIEobst (adjusted means = -42 and -39 mmHg, respectively) compared with control (adjusted mean = -26 mmHg) (P = 0.0012). Eobst was associated with an increase in mean oesophageal pressure while Iobst was associated with a decrease in mean oesophageal pressure. There were significant increases in mean pulmonary artery pressure in horses with CIEobst (adjusted means = 82 mmHg) and in pulmonary wedge pressure in horses with CIEobst and Iobst (adjusted means = 51, and 55 mmHg, respectively) when compared to control (73 and 42 mmHg, respectively) (P = 0.0001). Pulmonary capillary pressure was significantly increased in horses with CIEobst or Iobst (adjusted means = 61 mmHg, 63 mmHg, respectively) when compared to control (adjusted mean = 50 mmHg)(P = 0.0001). At maximal exercise intensity with inspiratory obstruction, the mean oesophageal (pleural) pressure was -17 mmHg while the mean pulmonary capillary pressure was 77 mmHg. The latter exceeds the reported 75 mmHg threshold for capillary failure in horses. We conclude that inspiratory resistive breathing can lead to a significant increase in transmural pulmonary capillary pressure which may contribute to loss of capillary integrity and rupture.

EFFECT OF PROPULSION MODE ON MAXIMAL HEART RATE AND RATINGS OF PERCEIVED EXERTION IN RUNNING

400 Different exercise modes tend to result in different maximal heart rates for the same person. This study examined the effects of propulsion mode on Maximal Heart Rate (HRmax) and Ratings of Perceived Exertion (RPE, Borg Scale, 15 points) while level running (0% slope). 14 male runners and thriathletes (34.3 ± 9.77 years) performed two tests on different days. Data were obtained during two identical protocols for each subject, one with external propulsion mode (motor, treadmill); and the other with self-propulsion mode (running on a track): 30 min. warm-up, at an exercise intensity of 60-70% HRmax (first value of HRmax estimated by age formula), followed by gradual increments of 1.6 Km/h every 30 s. until volitional fatigue. Subjects recovered until HR reached 60% HRmax. The increments and recovery were repeated a total of three times. The highest HR was chosen with its corresponding RPE. The order of tests was assigned randomly. Speed was controlled in the treadmill with the manual controls. On the track, a bicycle with a calibrated speedometer paced the runner at the corresponding speeds. RPE and HR were measured during warm-up period and during maximal effort (HRmax, RPEmax). (Table)TableThis results show that there is no effect of propulsion mode on Maximal Heart Rate, during level running, so athletes can perform HRmax tests both on a treadmill or on a track, even though there is a greater perceived exertion during the trial performed on a treadmill inside a laboratory, both at moderate intensities (60-70% HRmax) and at maximum exercise intensity. Supported by a Gatorade Sports Science Institute Student Grant.

Motor unit activation patterns during concentric wrist flexion in humans with different muscle fibre composition.

Muscle activity was recorded from the flexor carpi radialis muscle during static and dynamic-concentric wrist flexion in six subjects, who had exhibited large differences in histochemically identified muscle fibre composition. Motor unit recruitment patterns were identified by sampling 310 motor units and counting firing rates in pulses per second (pps). During concentric wrist flexion at 30% of maximal exercise intensity the mean firing rate was 27 (SD 13) pps. This was around twice the value of 12 (SD 5) pps recorded during sustained static contraction at 30% of maximal voluntary contraction, despite a larger absolute force level during the static contraction. A similar pattern of higher firing rates during dynamic exercise was seen when concentric wrist flexion at 60% of maximal exercise intensity [30 (SD 14) pps] was compared with sustained static contraction at 60% of maximal voluntary contraction [19 (SD 8) pps]. The increase in dynamic exercise intensity was accomplished by recruitment of additional motor units rather than by increasing the firing rate as during static contractions. No difference in mean firing rates was found among subjects with different muscle fibre composition, who had previously exhibited marked differences in metabolic response during corresponding dynamic contractions. It was concluded that during submaximal dynamic contractions motor unit firing rate cannot be deduced from observations during static contractions and that muscle fibre composition may play a minor role.

EFFECTS OF DIFFERENT WORK INTENSITY ON MUSCLE OXYGEN CONSUMPTION DURING INTERMITTENT EXERCISE

384 This study investigated an effect of different work intensity (maximal and VT work intensity) on changes in muscle oxygenation and on muscle oxygen consumption (muscle VO2) during the intermittent exercise. Eight healthy male subjects participated in this study. Determination of the maximal and VT work intensity resulted from incremental exercise test. The intermittent exercise consisted of; Ratio of work and rest periods during the intermittent exercise were 10 sec: 10 sec with 60rpm, total exercise time was 10 min. The changes of oxygenation were measured by near-infrared spectroscopy using continuous wave (NIRcws). In the present study, the changes of oxygenation resulted from the arterial occlusion at every 3rd repetitions of intermittent exercise. Thigh volume and the quadriceps femoris muscle mass were calculated from the formula by Jones and Pearson (1969). Oxygenation of VT work intensity exercise decreased until 50% level during exercise period and recovered from 90% level at rest period. Oxygenation of maximal work intensity exercise decreased until 20% level from resting level exercise period and recovered from 60% level at rest period. Muscle VO2 were 3.7± 0.23%/kg during resting condition, 20.6 ± 2.43%/kg during maximal work intensity and 27.5 ± 2.69%/kg during VT work intensity, respectively. In conclusion, the results obtained suggest that, during intermittent exercise, the maximal work intensity exercise more depend on anaerobic energy supply system than the VT work intensity exercise, considering that the maximal work intensity exercise restarted the exercise under the insufficient oxygenation condition (60%) compared to the VT work intensity exercise with sufficient oxygenation condition (90%).

Responsiveness of plasma 2- and 4-hydroxycatecholestrogens to training and to graduate submaximal and maximal exercise in an untrained woman. Interuniversity Project on Reproductive Endocrinology in Women and Exercise.

A single-subject experimental design was used to obtain some preliminary findings on the plasma responses of catecholestrogens (CE) to acute exercise and brief, but exhaustive training on a cycle ergometer. One previously untrained eumenorrheic female (body fat: 26% VO2max: 43.3 ml x kg(-1) x min[-1]) participated in this study. Resting CE levels were for "total" (unconjugated + conjugated) 2-hydroxyestrogens (2-OHE) 162pg/ ml and 350 pg/ml in the follicular (FPh) and luteal phase (LPh), respectively. Plasma total 4-hydroxyestrogen (4-OHE) levels were 41 pg/ml in the FPh and 66 pg/ml in the LPh. For "total" 2-methoxyestrogens (2-MeOE), we found 257 pgl/ml in the FPh and 374 pg/ml in the LPh. Resting levels of 2-hydroxy CE following a period of brief, intensive training were decreased during the LPh (2-OHE: -38%; 2-MeOE: -19%), whereas 4-hydroxy CE were unaffected. After training, the formation of CE as expressed by the 2-OHE:E and 4-OHE:E ratios, was increased by 75% and 200% at rest, respectively. CE activity or O-methylation, as estimated from the 2-MeOE:2-OHE ratio, was higher following training (FPh: +22%; LPh: +30%). During acute exercise before training, we observed a small rise proportional to the exercise intensity in the plasma "total" primary estrogen concentrations (FPh: +28%; LPh: +16%), and no changes in either 2-OHE or 2 MeOE levels. Plasma concentrations of 4-OHE, however, doubled during maximal exercise intensity. The 2-OHE:E and 2-MeOE:2-OHE ratios did not alter during incremental exercise. Training effects on acute exercise responses were only noticed for 4-OHE, which contrary to pre-training conditions, now progressively decreased. The major findings of this study are that in response to training: a) during rest, a greater proportion of CE are formed from a lower amount of precursor hormone, b) the rate of O-methylation of CE increases.

Cardiovascular responses to exercise in children.

The cardiovascular system of children responds to exercise differently than does that of an adult, although the mechanisms behind the differences are unclear. During dynamic exercise, it has been reported that heart rate (HR) response to the initiation of exercise is both faster and slower in children than adults. Furthermore, HR recovery has been reported to be faster in children. During submaximal steady state exercise, HR and total peripheral resistance are higher, while stroke volume [SV (ml)] and cardiac output [Q (L/min)] are lower in children at a given rate of work. At maximal exercise intensities HR is higher while SV and Q are lower in children than adults. Differences in cardiovascular responses to dynamic exercise between young boys and girls have also been reported. The majority of studies report that HR is lower and SV is higher in boys than girls at a given rate of work, although data to the contrary have been reported. These differences seem to be related to larger hearts in the boys. Further, the majority of the studies report that Q is similar in young boys and girls at a given rate of work. Few studies have reported differences between boys and girls at maximal intensities of exercise, and the results of those studies are inconsistent. Less is known about cardiovascular responses of children to static exercise compared with adults. A number of studies have reported that HR response to handgrip exercise is greater in children than adults, while others have reported no difference in this response. Even fewer studies have compared boys and girls in their cardiovascular response to static exercise and the results of these studies are also inconsistent. During prolonged exercise both children and adults exhibit cardiovascular drift (gradual increase in HR and decrease in SV). The direction and degree to which these changes differ between children and adults is unclear, with both greater and lesser responses being reported in children. Few studies have investigated differences in cardiovascular response to prolonged exercise between boys and girls. Those that have, report no difference between young boys and girls.

Influence of exercise-induced plasma volume changes on the interpretation of biochemical data following high-intensity exercise.

To assess the effects that exercise-induced plasma volume changes (PVCs) have on the interpretation of biochemical and hormonal parameters in the blood of athletes after high-intensity exercise. It was hypothesized that two unrelated high-intensity exercise protocols, performed by two separate subject groups each using different exercise modes, would result in similar percentage changes in plasma volume (% delta PV). It was further hypothesized that the % delta PV, measured in both protocols, would comparably influence the interpretation of biochemical variables measured following exercise. An experimental before-after trial on volunteers was performed. Two different exercise modes employing two different high-intensity acute exercise protocols were investigated. Eight male swimmers performed an interval training session (ITS) consisting of 15 x 100-m freestyle efforts at 95% of their maximal exercise intensity, and eight male runners performed a multistage discontinuous treadmill test (MSD) to volitional exhaustion. The Human Performance Laboratory at the Department of Human Movement at the University of Western Australia. Blood samples obtained before, immediately after, and 30, 60, and 120 min during recovery were analyzed for plasma volume changes, urea, uric acid, creatinine, albumin, calcium, iron, transferrin, testosterone, cortisol, and sex hormone-binding globulin (SHBG). The ITS and MSD protocols produced similar and significant alterations (p < 0.01) in plasma volume. Both protocols also elicited significant fluctuations (p < 0.01) in the concentration of most of the parameters measured (excluding iron). When albumin, transferrin, testosterone, and SHBG values were adjusted for the significant % delta PV, their concentrations did not change over the experimental period, suggesting that the changes in measured concentration of these parameters may be, in part, due to changes in plasma volume. However, urea, uric acid, creatinine, calcium, and cortisol, when corrected for % delta PVC, still demonstrated significant changes (p < 0.01). It is recommended, when sampling biochemical and hormonal parameters in blood following an acute bout of exercise, that corrections for PVCs should be conducted. Apparent changes in blood solutes may reflect PVCs. PVCs should be taken into consideration when interpreting results regardless of exercise protocol and exercise mode performed.