Teeth Research Articles

Complications of Intracanal Irrigation During Root Canal Therapy of a Maxillary Canine Tooth in a Cat.

This case describes a previously unreported complication of maxillary canine root canal therapy in a cat. A 5-year-old Russian Blue cat was presented with a complicated crown fracture (pulp exposure) of its left maxillary canine tooth (204). To salvage the tooth, root canal therapy was initiated but not completed due to hemorrhage within the canal. The procedure was staged. On recovery from the procedure, unilateral facial swelling and corneal ulceration were observed. This was consistent with retrograde passage of sodium hypochlorite through the nasolacrimal duct, inducing chemical injury to the cornea. The patient was treated with topical antibiotics, ophthalmic lubrication and systemic analgesia. After seven days of treatment, vast improvements to the eye were noted, with a full recovery confirmed at subsequent follow-up. Rather than complete stage two of the root canal therapy, the affected tooth was extracted; due to progression of pathology affecting the periapical bone. Clinicians should be aware of retrograde chemical irrigation as a potential complication when undertaking root canal therapy of maxillary canine teeth in cats. The close association between the maxillary canine tooth root and the nasolacrimal duct in cats needs to be taken into consideration and may require further evaluation prior to undertaking endodontic treatment. Advanced imaging should be considered. Immediate management of chemical corneal injuries should include copious flushing of the corneal surface, followed by swift referral for ophthalmic assessment.

The Value of a Tooth for Alveolar Ridge Management; Strategies to Manage Ankylosed Maxillary Anterior Teeth in Young Patients.

In the young and growing patient, tooth ankylosis impedes alveolar growth and presents a serious dilemma regarding the best treatment approach. Two common treatment approaches, extraction of the ankylosed tooth or a "wait and see" will result in a compromised alveolar ridge that can affect future prosthetic rehabilitation. The purpose of this article is to discuss five treatment strategies that can be utilized in the management of tooth ankylosis in the growing patient: (1) extraction, (2) decoronation or root submergence, (3) socket shield (partial extraction), (4) segmental osteotomy and (5) replacement with tooth autotransplantation. It is important to understand the biologic sequelae of ankylosis and the value of the tooth for alveolar ridge management. Strategies will be discussed with an emphasis on alveolar ridge management using a natural tooth and root. With an interdisciplinary team, treatment options can then be developed, to achieve more favorable long-term outcomes. An understanding of each of these procedures and the proper time for implementation will help the clinician achieve the most optimal long-term outcomes for these growing patients. There are several treatment options for traumatized ankylosed incisors in growing patients. This article will describe the details of these treatment strategies, emphasize the value of the tooth for ridge management and present guidelines about selecting the most optimal strategy based on age, rate of growth, condition of the traumatized tooth, and the definitive prosthetic plan.

Evaluation of root and root canal morphology of mandibular and maxillary canine teeth in Turkish subpopulation by cone beam computed tomography with using two classification systems

BackgroundKnowledge of root and canal morphology is a prerequisite for effective nonsurgical and surgical endodontic treatments. The aim of this cone beam computed tomography (CBCT) study was to evaluate the root canal morphology of permanent canines in a Turkish subpopulation using two classification systems.MethodsA total of 2,000 canine teeth were examined. The number of roots was identified, and root canal configurations were classified according to Vertucci’s classification and a new system for classifying root and canal morphology. Fisher’s exact test was used for statistical analysis, and the level of significance was set at 0.05 (p = 0.05).ResultsThe canal configuration type I was the most common in all canines, while type III was the second most common. According to the new system, the code 1C1−1 was the most common, whilst 1C1 (A1) codes were the second most common for all canines. In this study, more than 10% morphology that did not fit the Vertucci classification was detected. In the categorization of accessory canals based on the new classification, the most common type in all canines was 1C1,1 (A1). Age had an effect only on the morphology of the left maxillary canine (p < 0.05).ConclusionCanines in the Turkish subpopulation showed a relatively high degree of variation in root and canal anatomical variations. Clinicians should be aware of where canals converge or diverge to avoid missing canals. The new system for classifying canal morphology describes root and canal configurations more accurately and practically compared to the Vertucci classification.

A New Species of Herpetoreas Günther, 1860 (Serpentes: Natricidae) from Yunnan, China

A new species of the genus Herpetoreas is described from Yunnan Tongbiguan Provincial Nature Reserve, Yingjiang County, Dehong Prefecture, Yunnan Province, China. The new species can be separated from its congeners by a combination of the following characteristics: tail length to total length being 0.29, dorsal scales being all strongly keeled, 165 ventrals, divided cloacal plate, 89 pairs of subcaudals, 24 maxillary teeth, last two maxillary teeth being distinctly enlarged, approximately 13 white speckles presenting on anterior lateral surface of body, pale pink anterior venter, pink posterior venter, and rose red ventral tail. The genetic divergence between the new species and other species of this genus ranged from 6.7% to 13.0% in the mitochondrial cytochrome b gene. The new taxon represents the fifth species of the genus Herpetoreas in China and the first species of this genus in Yunnan Province.

Teeth arrangements for denture esthetics: perceptions of dentulous and edentulous individuals

While bearing in mind that differing opinions on esthetic outcomes can emerge among dentists, patients and observers during the rehabilitation of edentulous patients, this study compares esthetic perceptions of and preferences for various anterior teeth arrangements for complete dentures among both dentulous and edentulous individuals. Two edentulous individualswere selected, and four maxillary anterior teeth arrangements (“Classic”, “Supernormal”, “Senile”, “Youthful”) were proposed. Photographs were evaluated by the patients, prosthodontists and dentistry predoctoral students, as well as edentulous and dentulous laypeople. In the cases of both patients, most respondents did perceive differences among the arrangements,with no differences among groups (male patient, P=0.353; female patient, P=0.387). Considering all respondents, the “Youthful” and “Classic” arrangements were understood to be the most attractive (33/48%), natural (34/51%), least artificial (34/50%), and the preferred (34/56%) smile for the male and female patient, respectively. Within each rater group, the “Classic” arrangementwas rated as the least artificial (P=0.03) for the female patient. The “Senile” and “Youthful” arrangements were favored for the male patient, who preferred the “Senile” one. For the female patient, the “Classic” and “Supernormal” were favored, and she chose the “Supernormal” smile. The results highlight that esthetic perceptions and preferences can differ among dentulous andedentulous laypeople, dental professionals and patients. In addition, the same observer may have different opinions regarding tooth arrangements for different patients. Therefore, the patient´s opinion must be taken into consideration when determining the esthetic standards of smiles, and professionals should refrain from imposing their own esthetic preferences on patients.

Digital wear analysis of onlay restorations constructed from two pressable glass-based ceramics against natural enamel: An in vitro study

Background. The wear resistance of lithium disilicate glass ceramics remains inadequately understood. Therefore, the primary objective of this in vitro study was to digitally assess the wear characteristics of lithium disilicate and zirconia-reinforced lithium disilicate pressable ceramics following chewing simulation. Methods. Twenty-two onlay ceramic restorations were fabricated on epoxy dies replicated from the maxillary first premolar ivory tooth master die. The onlay samples were randomly allocated to two equal groups (n=11) based on the material used: group L (lithium disilicate [IPS e.max Press]) and group Z (zirconia-reinforced lithium disilicate [Vita Ambria]). Self-adhesive resin cement was used to cement all of the samples. Each sample was occluded with the buccal cusps of healthy human upper first premolar teeth (n=22). Subsequently, all the samples were scanned using an intraoral scanner (Medit i500) at baseline and after chewing simulation. The acquired standard tessellation language (STL) files of baseline and post-chewing simulation data were superimposed, and the volumetric loss (mm3) and wear depth (μm) of the materials and their enamel antagonists were calculated. Statistical analysis was performed using independent t-test (P=0.05). Results. There was no statistically significant difference in the wear behavior of Vita Ambria compared to IPS e.max (P&lt;0.05). Similarly, there was no statistically significant difference in the wear behavior of their enamel antagonists (P&lt;0.05). Conclusion. IPS e.max Press and Vita Ambria ceramics demonstrated comparable wear behavior.

Advantages of using touch-controlled, minimally invasive implantation technique on soft tissue in the aesthetic zone of maxillary anterior teeth.

Endosseous implant is an ideal treatment option for the treatment of denture defects and omissions. However, how to maintain the perfect gum contour of patients has been an important research topic for stomatologists and has attracted much attention. The objective of this study was to explore the advantages of minimally invasive touch-controlled implantation in maintaining soft tissue morphology in the aesthetic area of maxillary anterior teeth. Forty patients underwent preoperative cone-beam computed tomography and were randomly divided into 2 groups: experimental group (touch-controlled, minimally invasive implantation approach, n = 20) and control group (traditional flap implantation approach, n = 20). The operative time, postoperative pain, gingival recession, and patient satisfaction were compared between the 2 groups. The independent sample t test was employed to compare the results, with a significance level of α = 0.05. Statistical significance was determined at P < .05. The operative time was 4.50 and 9.21 minutes, respectively, for 2 groups, P < .001. The mean pain scores of 2 groups were 1.09 and 2.14, respectively, at 24 hours after surgery, P < .001. The H values (the distance from the labial edge of the implant healing cap to the lowest gingival margin), 6 weeks after surgery, of 2 groups were 2.69 and 3.05, respectively, P = .023. There was a significant difference in patient satisfaction between 2 groups 24 hours after surgery (P < .001). Touch-controlled minimally invasive implantation has shorter operative time and lesser bleeding, postoperative pain, and gingival recession than traditional flap implantation, which is conducive to the preservation of gingival shape.

A new species of Phyllophichthus Gosline, 1951 (Actinopterygii, Ophichthidae) from Taiwan.

A unique species of the flappy-snake eel genus, Phyllophichthusdiandrus sp. nov., is described based on a single specimen (270 mm in total length) collected from Dong-gang, southwestern Taiwan. The new species possesses several characters that are distinct from the only other species in the genus, Phyllophichthusxenodontus. Phyllophichthusdiandrus sp. nov. can be easily distinguished from P.xenodontus by having two papillae inside of nasal tube (vs three in P.xenodontus), 25 branchiostegal rays (vs 29), the dorsal-fin origin positioned behind the tip of the pectoral fin (vs not behind, usually above mid-pectoral fin), and the absence of the maxillary teeth (vs present). The relationship between Phyllophichthus and Leiuranus is discussed based on generic and morphological features.

Additive manufacturing trueness and internal fit of crowns in resin modified with a commercially available ceramic composite concentrate

Inorganic fillers can be incorporated into additively manufactured (AM) resins to improve their properties, and a ceramic composite concentrate has been recently marketed for this purpose. However, knowledge on the printability of AM resins modified with this concentrate is lacking. The purpose of this in vitro study was to evaluate the manufacturing trueness and internal fit of AM crowns in a dental resin modified with a commercially available ceramic composite concentrate. A maxillary right first molar typodont tooth was prepared and digitized to design a crown in standard tessellation language (STL) format. This STL file was used to fabricate a total of 30 AM crowns, 10 with a resin with no fillers for interim restorations (AM-I), 10 AM-I resin incorporated with ceramic composite concentrate (AM-IR), and 10 with a ceramic-filled resin intended for definitive restorations (AM-D). The modification of the AM-IR resin was performed by mechanically mixing 30wt% of a commercially available ceramic composite concentrate into AM-I. An intraoral scanner was used to digitize all crowns, which were then seated on the prepared typodont abutment and rescanned. The manufacturing trueness of each crown was measured in 4 regions (overall, external, intaglio, and marginal) and reported with root mean square (RMS) estimates. The internal gaps were calculated by using a triple scan protocol. The intaglio surface deviations were assessed with the Kruskal-Wallis and Dunn tests, while the remaining data were analyzed with the 1-way analysis of variance and Tukey honestly significant difference tests (α=.05). AM-IR had the highest overall and external RMS and had higher intaglio RMS than AM-D (P≤.001). AM-I had the lowest marginal RMS (P≤.002). AM-IR had the highest average gap values (P≤.027). AM-IR crowns mostly had lower trueness and high internal gaps. However, the differences among the tested materials in fabrication trueness and average gap values were small, and internal gaps were within the previously reported thresholds.

A clinical study of anterior maxillary impacted supernumerary teeth based on the classification of horizontal and vertical positions

A clinical study of anterior maxillary impacted supernumerary teeth based on the classification of horizontal and vertical positions

The Impact of platelet rich plasma on upper canine rotation after maxillary teeth En-masse retraction

The Impact of platelet rich plasma on upper canine rotation after maxillary teeth En-masse retraction

Frenectomy for supporting diastema closure correction in orthodontic patients

Introduction: The maxillary frenulum can cause aesthetic problems or jeopardize orthodontic results in cases of central diastema, causing relapse after treatment. One of the etiologic factors of central diastema persistence is an aberrant frenulum. The most common way to diagnose frenulum attachment is with the blanch test. One of the treatments for aberrant frenulum is frenectomy. Frenectomy can reduce the risk of relapse from central diastema closure. The purpose of this case report is to describe the stages of frenectomy in a case of maxillary central diastema. Case report: A 24-year-old woman came to the Periodontics Specialist Clinic due to a referral from the Department of Orthodontic, Dental Hospital Universitas Airlangga with complaints of loose maxillary front teeth and planned to be treated using fixed orthodontic devices at Department Orthodontic. The blanching test examination showed that the labial frenulum was in the high frenulum category. Case management: Frenectomy was performed using a scalpel. After extraoral and intraoral asepsis, infiltration anesthesia was performed on the labial and palatal sides of tooth 11,21. Clamp the maxillary labial frenulum using a hemostat and then incise the frenulum using blade no 15c in a V shape, then incise the frenulum attachment on the interdental to the palatal region with an elliptical incision. Interrupted suturing using Nylon thread size 4.0. The surgical area was closed using a periodontal pack. Suturing was removed on day 14. Follow-up at 19 months showed no diastema in the anterior maxilla, the patient wore a retainer in the maxilla and a fixed retainer in the mandible. There were no further complaints after the treatment. Conclusion: Frenectomy before orthodontic treatment helps accelerate the treatment progress to correct the central diastema.

Inter-septal bone reduction: Impact on space closure, root resorption and canine angulation during en-masse retraction - a randomised controlled trial.

To compare the space closure, root resorption and canine angulation during en-masse retraction of the labial segment after extraction of first premolars with or without interseptal bone reduction distal to the maxillary canines. A single-centre, parallel randomised control trial included 16 participants with a mean age of 21.5 years. Participants were allocated into treatment groups using blocked randomisation, and blinding was employed for outcome assessors and data analysts. The control group consisted of eight participants who underwent therapeutic extraction of maxillary first premolars, while the experimental group included eight participants who underwent interseptal bone reduction immediately after premolar extraction. En-masse retraction was performed using conventional friction mechanics with absolute anchorage in both groups. Measurements of space closure were conducted over 3 consecutive months during retraction. The time taken for total space closure was recorded. Cone-beam computed tomography scans were taken before and 3 months after retraction to assess root resorption and canine angulation. The experimental group demonstrated a significant increase in the rate of en-masse retraction compared to the control group over 3 months (mean difference [MD] = 1.09 mm, 95% confidence interval [CI] = 0.78-1.40), with an overall space closure rate of MD 0.26 mm/month (95% CI = 0.17-0.34). However, these changes were of minimal clinical significance. The change in canine angulation (MD = 4.50°, 95% CI = -1.61-10.61) did not exhibit statistical significance. Substantial root resorption was observed in six maxillary anterior teeth, with no difference between the groups. Interseptal bone reduction is a minimally invasive surgical technique, resulting in a notably accelerated rate of en-masse retraction in the experimental group over 3 months. However, despite the statistical significance, the clinical impact on overall space closure was minimal, with a difference of only 0.26 mm/month observed between the groups. Interseptal bone reduction did not affect the change in canine angulation and root resorption.

Correction of Impacted Maxillary Permanent Anteriors - A Case Report.

The maxillary anteriors play the most prominent role in an individual's aesthetics, speech, and majorly psychology. The impaction of maxillary anterior teeth can be a challenging orthodontic problem that can be managed by interceptive orthodontics in early mixed dentition. In this particular case report, interceptive orthodontics alone may not bring desirable results because two problems need to be dealt simultaneously, namely, intraosseous crowding and midline shift due to impaction on the affected quadrant. In the article, a novel approach is being discussed, where aesthetics of the child was compromised due to impacted rotated maxillary anteriors that were exposed using soft tissue laser and allowed to erupt by selective removal of primary and permanent first premolar teeth on the affected side alone, leading to spontaneous alignment of arch discrepancy and relative correction of midline shift. A unilateral serial extraction sequence (D-4-C) would be effective treatment of choice. This approach adds psychological benefit to the child by using soft tissue lasers and unilateral serial extraction.

Comparative Evaluation of Microleakage in Class II Composite Restorations Using Three Bulk-fill Composites with or without Resin-modified Glass Ionomer Cement Liner: A Stereomicroscopic Study.

To compare the microleakage of three bulk-fill composite resins with or without resin-modified glass ionomer cement (RMGIC) liner. A total of 30 maxillary human 1st premolar teeth were selected. Two box preparations were made on the mesial and distal sides. Teeth were randomly divided into three groups of 10 teeth each. RMGIC liner with 1 mm thick were applied to the mesial box. The specimens were divided into three groups according to the type of bulk-fill composites used and restoration of the cavities were done according to manufacturer instructions and light cured. Finishing and polishing were done and stored for 1 week in distilled water at 37°C. Thermocycling was then performed in a thermocycling unit. The specimens were then immersed in 0.5% methylene blue for 8 hours at 37°C. All the specimens were sectioned longitudinally in a mesiodistal direction and analyzed under 20× magnification in a stereomicroscope. The degree of dye penetration was scored. Subgroup M showed comparatively less microleakage compared to subgroup D in all the groups which was statistically significant. When microleakage between the study group on mesial and distal sides was compared, group smart dentin replacement (SDR)-M showed less microleakage compared to group F-M and this difference was statistically significant. RMGIC is the recommended liner beneath the bulk-fill composites in class II cavities and SureFil SDR bulk-fill flowable can be the recommended composite resin for class II restorations. Bulk-fill composite is a time-saving material as it eliminates the incremental placement. RMGIC is always recommended beneath bulk-fill composites. SDR bulk-fill is the recommended composite restoration. Mundaragi VAC, Niranjan NT, Chandrashekhar KS, et al. Comparative Evaluation of Microleakage in Class II Composite Restorations Using Three Bulk-fill Composites with or without Resin-modified Glass Ionomer Cement Liner: A Stereomicroscopic Study. Int J Clin Pediatr Dent 2024;17(10):1146-1152.

Enhancing Localized, Occlusal Space by Relative Axial Tooth Movement in Patient with Dentinogenesis Imperfecta—A Case Report

ABSTRACT Dentinogenesis imperfecta (DI) is a hereditary disorder that affects dentin formation, leading to discolored, fragile teeth with increased susceptibility to wear and fracture. A 41-year-old woman presented with a family history of DI and significant tooth wear primarily affecting her maxillary anterior teeth due to parafunctional habits. She reported dissatisfaction with her smile, indicating that her front teeth were short and did not show when smiling. Examination revealed blue-gray teeth with craze lines characteristic of DI, receded pulp chambers, and evidence of significant tooth surface loss due to attrition. The patient had no significant medical history or allergies, with a regular history of dental attendance. The management plan involved restorative treatment using a staged approach. Initially, non-surgical debridement, management of caries, and the placement of provisional restorations using a fixed Dahl appliance were performed to create occlusal space. This was followed by definitive ceramic restorations to restore esthetics and function. The treatment successfully improved the patient’s smile and functional outcomes. This case highlights the importance of a comprehensive, phased treatment approach for managing DI, emphasizing the need for occlusal space creation, caries management, and esthetic restoration to improve patient satisfaction and dental health outcomes.

Assessment of the Bond Strength of Orthodontic Bracket on Ceramic Crown Surface Using Three Various Bonding Agents: A Comparative Study.

The current study's aim was to evaluate the orthodontic bracket's bond strength employing three different bonding agents on a ceramic crown surface. Tooth preparation on 60 permanent maxillary premolar teeth extracted for orthodontic purposes was carried out. Supragingival finishing margins were made for all samples, and ceramic (PFM) crowns were fabricated. Following crown cementation on the prepared samples, they were divided into three experimental groups randomly (n = 20) as follows: group I: Bracket bonding using Transbond XT bonding agent; group II: Bracket bonding using RelyXTM Unicem bonding agent; and group III: Bracket bonding using Assure Plus bonding agent. A universal testing machine was utilized to conduct the shear bond strength test. Using a stereomicroscope with a 10× magnification, adhesive remnant index scores were also used to assess the adhesive that was remaining on the surfaces. Data was recorded and statistically analyzed. The highest bond strength was found in RelyXTM Unicem bonding agent (19.38 ± 0.84) followed by Transbond XT bonding agent (17.12 ± 1.04) and Assure Plus bonding agent (16.14 ± 1.02). A highly significant difference was found between Transbond XT vs RelyXTM Unicem groups and RelyXTM Unicem vs Assure Plus groups. There was no significant difference found between Transbond XT and Assure Plus (p > 0.001). Adhesive Remnant Index scores showed that score 1 was higher [7 (35%)] in the Transbond XT bonding agent group. Score 1 was 8 (40%) and score 2 was 6 (30%) in RelyXTM Unicem bonding agent groups and in Assure Plus bonding agent group, score 2 was higher [9 (45%)]. In conclusion, RelyXTM Unicem exhibited superior bond strength with ceramic crowns when compared to Assure Plus and Transbond XT bonding agents. One of the most important steps in orthodontic therapy is bonding brackets to the teeth. A high enough and long-lasting bond between brackets and artificial surfaces is necessary for orthodontic treatment to be successful, as is the requirement for a bonding agent with the highest possible binding strength. The necessity for a more dependable process to glue the artificial crown surface has arisen due to the rise in adult patients seeking fixed orthodontic treatment. How to cite this article: Brajendu, Haque I, Sam G, et al. Assessment of the Bond Strength of Orthodontic Bracket on Ceramic Crown Surface Using Three Various Bonding Agents: A Comparative Study. J Contemp Dent Pract 2024;25(8):762-765.

Reliability of the digital functionally generated path technique for assessing occlusal interferences and adjusting CAD-CAM zirconia crowns: an in vivo study

BackgroundDesigning the occlusal surface of a prosthesis to ensure optimal eccentric occlusion is challenging without precisely replicating the patient’s mandibular movements. During the CAD-CAM prosthesis delivery process, clinicians often need to make adjustments to the prosthesis to avoid occlusal interferences that may occur during lateral excursions. Recently, there have been developments in the field of mandibular motion tracking using optical devices. These approaches seek to incorporate an individual’s functional movement into the research field of occlusal morphology.AimThis study aimed to assess the accuracy of digitally replicating mandibular movements to identify and correct occlusal interferences in monolithic CAD-CAM zirconia crowns.MethodsAn intraoral scanner (IOS) was used to capture complete arch maxillary and mandibular teeth and record buccal and lateral interocclusal records of maxillary first premolar abutment teeth of thirteen participants. For each patient, two monolithic zirconia crowns were fabricated following the standard digital workflow. The crowns were categorized based on the virtual method used for adjusting occlusal interferences into two groups: Group I, where occlusal interferences in CAD-CAM zirconia crowns were adjusted using buccal interocclusal records, and Group II, where adjustments were made using both buccal and lateral interocclusal records. After crown fabrication following the manufacturer’s instructions, occlusion was analyzed using an electronic pressure analyzer. The mean, standard deviation and median values of the recorded data were measured. Paired t test and Wilcoxon Sign Rank test were executed for analyzing differences between groups (p value ≤ 0.05).ResultsGroup I recorded higher maximum pressure at lateral mandibular movement with mean ± standard deviation value of 26.00 ± 4.95% than Group II with 20.62 ± 3.38%. Regarding pressure recorded at maximum intercuspation (MI) Group I showed higher results; 8.08 ± 1.50% compared to Group II with 7.23 ± 1.59% mean ± standard deviation value. The average value of crown volume for Group I was (160.36 ± 15.94) mm3, while for Group II was (157.63 ± 14.45) mm3.ConclusionsThe digital functionally generated path technique allows for identifying occlusal interferences and modifying CAD-CAM zirconia crown designs.

Management of Maxillary Anterior Tooth with Open Apex by MTA Apexification

Management of Maxillary Anterior Tooth with Open Apex by MTA Apexification

Radiological Outcome of Calcium Hydroxide as A Root Canal Sealer Constituent

Background: The effectiveness of root canal sealers plays a crucial role in the success of endodontic treatments by preventing microbial leakage and promoting periapical healing. This study aimed to compare the radiological outcomes of calcium hydroxide-based sealers and zinc oxide eugenol sealers in treating teeth with periradicular pathosis.Methods: This cross-sectional observational study was conducted at different private clinics, Dhaka, Bangladesh during the period from January 2019 to December 2019. A total of 60 permanent teeth with periradicular pathosis were randomly assigned into two groups: Group 1 (n=30), treated with zinc oxide eugenol sealer, and Group 2 (n=30), treated with calcium hydroxide-based sealer. Clinical evaluations were conducted on days 2 and 7 post-treatment, and radiological evaluations were performed at 3, 6, and 12 months. Data were analyzed using SPSS version 22.Results: The majority of participants were aged 11-30 years, with a higher proportion of males in both groups. Trauma was the leading etiological factor, with maxillary teeth being more frequently affected. Group 2 showed significantly better radiological outcomes, with 80.00% exhibiting reduced periapical pathosis size at 3 months, compared to 26.67% in Group 1 (p &lt; 0.001). At 6 months, 93.33% of Group 2 showed reduced pathosis size, compared to 60.00% in Group 1 (p = 0.002). At 12 months, 96.67% of Group 2 and 83.33% of Group 1 showed reduced pathosis size (p = 0.194). The final success rate was 96.67% in Group 2 and 86.67% in Group 1, with no statistically significant difference (p = 0.353).Conclusion: Calcium hydroxide-based sealers provide superior radiological outcomes compared to zinc oxide eugenol sealers in the treatment of teeth with periradicular pathosis. These findings support the use of calcium hydroxide sealers for enhanced endodontic treatment outcomes.