Maxillary Bone Volume Research Articles

Three-dimensional assessment of the skeletal characteristics accompanying unilateral maxillary canine impaction: a retrospective cone-beam computed tomography study

BackgroundEnvironmental and genetic factors associated with canine impaction have been extensively researched, whereas the bone characteristics in the impaction area have not been thoroughly studied. Accordingly, the objective of this investigation was to provide a skeletal assessment in terms of bone density, bone microstructure, bone volume, and palatal volume in subjects with unilaterally impacted maxillary canines.MethodsA retrospective design has been employed to address the aim of this study, where the initial pre-treatment cone-beam computed tomography (CBCT) scans of 30 patients with unilateral maxillary canine impaction were assessed. The obtained patients’ data were equally divided according to the location of the impaction into 2 groups, one with buccally impacted canines, and another with palatal impactions, with the contra-lateral sides in both groups serving as the controls. Skeletal measurements such as bone density (BD), bone microstructure in terms of fractal dimension (FD), maxillary bone volume (MBV), and palatal volume (PV) were evaluated from the acquired CBCTs in both groups and compared to the controls.ResultsWith buccal impactions, significantly greater BD and FD have been reported (p < 0.001), whereas non-significant differences were found regarding the PV when compared with controls (p = 0.56). MBV was significantly greater on the non-impaction side in comparison with buccal impaction sides (p < 0.001). For palatal impactions: BD, FD, and MBV were significantly greater on the impaction sides (p < 0.001), and conversely with PV which has been reported to be significantly greater on the non-impaction sides (p < 0.001).ConclusionsAs per the obtained results, buccally impacted canines are associated with greater BD and FD, and less MBV, whereas palatally impacted canines are accompanied with greater BD, FD, and MBV, in addition to less PV, when both conditions are compared with the non-impaction sides.

Zygomatic Implant Rehabilitation: A Prosthodontic Driven Approach: A Review

Zygoma implants, sometimes called zygomatic implants, are different from conventional dental implants in that they are affixed in the zygomatic bone, not the maxilla. They can be used in situations when there is not enough maxillary bone, either in terms of quantity or consistency, to support a dental implant. Insufficient maxillary bone volume may result from a combination of maxillary sinus pneumatization and bone resorption. To guarantee proper implant survival, the normal implant placement in the posterior maxilla requires a bone height of about 10 mm. Increased bone volume can be achieved by sinus elevation and bone grafting techniques in cases when there is insufficient bone available. The drawbacks of bone grafting procedures in the jaws include the need for prolonged care, restrictions on denture wear, morbidity at the donor surgical site, and graft rejection. Keywords: Zygomatic implants, Prosthodontic Rehabilitation, Prosthetically driven approach

Evaluation of nasal septal deviation and maxillary bone and nasal airway dimensions and volumes using cone-beam computed tomography in patients with unilateral palatal canine displacement: a retrospective study.

To detect any association between palatally displaced canine (PDC) and nasal septal deviation (NSD), palatal bone thickness and volume, and nasal airway dimensions and volume. A total of 92 patients were included and subdivided into two groups: group 1, unilateral PDCs (44 patients), and group 2, normally erupted canines (NDCs) (48 subjects). The following variables were measured using cone-beam computed tomography: presence and type of NSD, nasal width, inferior conchae, hard palate and nasal septum thickness, maxillary bone and nasal airway volumes. NSD was detected in 77% and 50% of PDC and NDC subjects, respectively. Within the PDC subjects, significant differences between the displaced and nondisplaced sides were detected. Palate thickness was increased in the canine region and reduced in the molar region. Compared with the control group, PDC subjects had reduced palate thickness and lower nasal airway volume. Two predictors were significant for predicting the odds of PDC occurrence: NSD and maxillary bone volume. NSD is more frequent in PDC subjects. PDC subjects have reduced palate thickness and decreased nasal airway volume. In the presence of NSD, the odds of developing PDC increase by 3.35 times, and for each one-unit increase in the maxillary bone volume, the odds of developing PDC decrease by 20%.

Simultaneous sinus elevation and immediate implant placement without biomaterial: A technical note

Sinus floor elevation is widely considered as one of the most reliable and predictable procedures for augmenting posterior maxillary bone volume before implant placement. The lateral window technique is often described as the gold standard, especially when dealing with limited residual bone height. Traditionally, severe vertical defects in the posterior maxilla required a two-stage approach: first elevating the sinus membrane with biomaterial, followed by a second surgery for implant placement. This article introduces an innovative approach to the lateral sinus lift procedure, enabling simultaneous implant placement in sites with less than 5 mm of remaining bone height. This original one-stage surgical approach is interesting because it does not involve grafting of any biomaterial into the sinus. Its main objectives are to enhance safety and predictability while reducing the risk of post-operative infections. However, it's essential to emphasize that achieving an ideal implant position with adequate primary stability is crucial for its viability.

Evaluation of maxillary canine root and maxillary bone thickness and density in patients with displaced maxillary canines: A cone-beam tomography study

This study investigated lateral incisor and canine morphology and dimensions, maxillary bone density, and volume in subjects with displaced maxillary canines. Cone-beam computed tomography images for 134 palatally displaced canines (PDCs), 57 buccally displaced canines (BDCs), and 87 nondisplaced canines (NDCs) were analyzed. Canine and lateral incisor dimensions, alveolar bone dimensions, and maxillary bone volume and density were measured. The root length of BDCs was short compared with NDC and PDC groups. The lateral incisor was short in the PDC group compared with NDC and BDC groups. In the BDC group, maxillary bone volume was reduced compared with NDCs and PDCs. Significant differences were detected between BDC and PDC groups in bone density buccal to canines and between BDC and NDC groups in bone density distal to canines. The density of maxillary bone was the highest in the PDC group and the lowest in the BDC group compared with the NDC group. Eight variables were associated with the site of maxillary canine displacement: lateral incisor tip, alveolar bone density, alveolar bone width, bone density buccal to canine, canine width labiopalatally, maxillary bone volume, and canine midsagittal width. In PDCs, the maxillary lateral incisor was short, the canine root had a larger crown/root ratio, and maxillary bone volume was increased compared with NDCs. In BDCs, the canine root was shorter than NDCs and PDCs, maxillary bone volume was reduced compared with NDCs, and bone density at the buccal side was reduced compared with the PDC group.

Fluid Dynamic Transcrestal Sinus Floor Elevation Using a New Surgical Instrument, Flusilift and Hyaluronic Acid as Only Biomaterial: A Case Report

Despite validated surgical techniques and the development of biomaterials, the procedures aimed at increasing the maxillary bone volume by sinus floor elevation have complications with various degrees of relevance. The perforation of the Schneiderian membrane is one of the most frequent events while performing the detachment of the membrane and it can increase the risk of iatrogenic sinusitis, impairment of functional homeostasis, dispersion of the graft material in the antral cavity as well as its bacterial colonization with a subsequential failure of the procedure. This report presents a case where transcrestal sinus lift was performed using Flusilift (Sweden &amp; Martina, Due Carrare PD), a new instrument that allows fluid dynamic elevation of the sinus floor using saline solution to detach the Schneider’s membrane in an atraumatic way without using a sinus elevator and obtain an adequate alveolar ridge regeneration using hyaluronic acid in gel formulation to support an implant placement. Hyaluronic acid seems to play a key role in wound healing and contributes to a faster bone neoformation in bone regeneration procedures.

Does different cranial suture synostosis influence orbit volume and morphology in Apert syndrome?

This study was performed to compare the orbital and peri-orbital morphological variations in Apert syndrome patients with different cranial vault suture synostosis, so as to provide an anatomic basis for individualized surgical planning. Computed tomography scans of 57 unoperated Apert syndrome patients and 59 controls were subgrouped as follows: type I, bilateral coronal synostosis; type II, pansynostosis; type III, perpendicular combinations of cranial vault suture synostoses. Orbit bony cavity volume was significantly reduced in type I and type II, by 19% (P < 0.001) and 24% (P < 0.001), respectively. However, the reduction of orbital cavity volume in type III did not reach statistical significance. Globe volume projection beyond the orbital rim, however, increased by 76% (P < 0.001) in type III, versus an increase of 54% (P < 0.001) in type I and 53% (P < 0.001) in type II, due to different ethmoid and sphenoid bone malformations. Maxillary bone volume was only significantly reduced in type I bicoronal synostosis (by 24%, P = 0.048). Both type I and type II developed relatively less zygoma and sphenoid bone volume. Different cranial vault suture synostoses have varied influence on peri-orbital development in Apert syndrome. Instead of mitigating the abnormalities resulting from bicoronal synostosis in type I, additional midline suture synostosis worsens the exorbitism due to a more misshaped ethmoid.

Effect of the maxillary bone volume on the stress distribution that bone around dental implants

Effect of the maxillary bone volume on the stress distribution that bone around dental implants

Zygomatic Implants: A Review

Zygoma implants (or zygomatic implants) vary from traditional dental implants in that they attach in ratherthan maxilla (upper jaw) in the zygomatic bone (cheekbone). They can be used where the consistency orquantity of maxillary bone is insufficient for normal dental implant placement. Inadequate maxillary bonevolume can be due to bone resorption as well as maxillary sinus pneumatization or a mixture of both. Therequired bone height for typical implant placement in the upper jaw posterior area should be approximately10 mm to ensure appropriate implant survival. Where there is inadequate bone available, bone graftingprocedures and sinus raising procedures should be done to increase bone volume. Procedures for bonegrafting in the jaws have the downside of extended care, limiting denture wear, the morbidity of donorsurgical site &amp; graft rejection.

Combined use of splinted labial lithium disilicate veneers and a bonded nickel-chromium alloy palatal splint for tooth stabilization: A clinical report with 4-year follow-up

This clinical report describes the restoration of severely compromised maxillary teeth in a 20-year-old woman secondary to excessive root shortening and minimal bone support but surrounded by healthy and esthetic soft tissues. The maxillary bone volume precluded provision of an implant-supported fixed or removable dental prosthesis without extensive grafting procedures. Splinted labial lithium disilicate veneers and a bonded nickel-chromium alloy palatal splint were used to stabilize and retain the structurally compromised maxillary teeth. At the 4-year review, the splinted veneers remained intact.

Association of Mandibular Dysplasia With Maxillary Volumetric and Linear Measurements in Children With Hemifacial Microsomia.

In hemifacial microsomia (HFM), the correlations between mandibular dysplasia and maxillary deformities in HFM patients have not yet been assessed. The objective of the present study was to examine the association of maxillary volumetric and linear measurements with mandibular ramus height or corpus length on the affected side in children with unilateral HFM.In this retrospective research, a total of 70 children with unilateral HFM were enrolled at our department from 2010 to 2019. Demographic information was recorded, and computed tomographic scan were reconstructed and analyzed by segmentation, volumetric, and cephalometric measurements. Analyses involved independent sample t-test, univariable, and multivariable linear regression.In the overall population, mandibular ramus height (MRH) was positively associated with the maxillary bone volume (MBV) (r = 0.484, P < 0.001) and maxillary total volume (MTV) (r = 0.520, P < 0.001). Similarly, mandibular corpus length (MCL) was significantly associated with the MBV (r = 0.467, P < 0.001) and MTV (r = 0.520, P < 0.001). Multivariate regression analysis revealed that the MRH or MCL were significantly and independently associated with MBV or MTV (MRH/MBV β = 0.420, P < 0.001; MRH/MTV β = 0.391, P < 0.001; MCL/MBV β = 0.403, P < 0.001; MCL/MTV β = 0.307, P < 0.01).These results demonstrated that the MBV and MTV are independently associated with MRH or MCL on the affected side in children with unilateral HFM, suggesting a potential interaction between mandibular dysplasia and maxillary deformities.

Three-Dimensional Measurement of Maxillary Involvement in Hemifacial Microsomia in Children.

In hemifacial microsomia (HFM), the aberrant mandible structure has always been the focus of attention. How the maxillary development being affected is not clear. The authors sought to comprehensively evaluate the hemifacial maxillary deficiency and to assess for Pruzansky-Kaban score correlation.This is a retrospective research of children with HFM. Demographic information were recorded, and computed tomographic scan were reconstructed and analyzed by segmentation, volumetric and cephalometric measurements. Analyses involved paired t-test, independent sample t-test and one-way analyses of variance.Demographic information revealed 67 patients diagnosed with HFM were included: 10.4 percent type I, 38.8 percent IIa, 28.4 percent type IIb, 22.4 percent type III. The maxillary total volume was found to be significantly decreased on the affected side in patients with type IIa (P = 0.0426) and IIb (P = 0.0004). No notable differences in maxillary sinus volume were found. No significant differences in maxillary width measurements were found between groups type I and III. A descending trend in maxillary bone volume ratio, an increasing trend in maxillary posterior width ratio and a decreasing trend in maxillary middle height ratio was observed from group I to IIb (pmbv* = 0.020; pmpw* = 0.002; pmmh* = 0.004).This study comprehensively characterized the hemifacial microsomia maxillary deficiency. For maxillary total volume and transverse development, the type III group presented characteristics similar to the type I group. We concluded that the severity of maxillary deficiency is not completely consistent with the mandibular deformity classification.

Sclerostin-Neutralizing Antibody Enhances Bone Regeneration Around Oral Implants.

Dental implants are an important option for replacement of missing teeth. A major clinical challenge is how best to accelerate bone regeneration and reduce the healing time for functional restoration after implant placement. A sclerostin-neutralizing antibody (Scl-Ab) has been shown to enhance alveolar bone formation and fracture repair. The aim of this study was to investigate the effects of systemic administration of Scl-Ab on dental implant osseointegration and bone regeneration in an experimental alveolar ridge tooth extraction model. To investigate the effects of Scl-Ab on bone regeneration and dental implant osseointegration, an experimental alveolar bone osteotomy rat model was adopted. One month after extraction of maxillary right first molars, osteotomy defects were created at the coronal aspect of each of the extraction sites, and 1 × 2-mm custom titanium implants were installed into the osteotomies. Coincident with implant placement, Scl-Ab was administered subcutaneously at a dose of 25 mg/kg twice weekly for 10-28 days and compared with a vehicle control. Animals were sacrificed 10, 14, and 28 days after surgery, and maxillae were harvested and analyzed by microcomputed tomography (microCT), histology, and histomorphometry. microCT analysis demonstrated that the maxillary bone volume fraction was approximately 2- to 2.5-fold greater in Scl-Ab-treated animals compared with vehicle alone at days 14 and 28. Consistent with those findings, two-dimensional bone fill percentages within the coronal osteotomy sites were highest in Scl-Ab treatment groups at 28 days. In addition, bone-implant contact at 28 days was approximately twofold greater in the Scl-Ab group compared with the vehicle control. These results indicate that systemic Scl-Ab administration enhances osseointegration and bone regeneration around dental implants. This approach offers potential as a treatment modality for patients with low bone mass or bone defects to achieve more predictable bone regeneration at alveolar bone defects and to enhance dental implant osseointegration.

Morbidity of anterior iliac crest and calvarial bone donor graft sites: a 1-year randomized controlled trial

Autogenous bone graft harvesting is still commonly considered the gold standard for the reconstruction of a severely resorbed maxillary alveolar ridge; however, the preferred donor site remains a subject of debate. This study compared the morbidity of calvarial and iliac crest donor sites after harvesting. Twenty edentulous patients with an insufficient volume of maxillary bone for reliable implant placement were assigned randomly to either calvarial (n=10) or anterior iliac crest (n=10) bone harvesting groups. All patients underwent a maxillary sinus floor elevation procedure combined with widening of the alveolar process using buccal bone blocks. Donor site morbidity was assessed before, during, and at 1year after the surgery through patient questionnaires, physical examination, and medical records. No perioperative complications occurred. The anterior iliac crest group reported minor postoperative pain after harvesting. The scars after calvaria harvesting were significantly longer (P=0.003), but this was not bothersome for the group of patients. Long-term pain was negligible and satisfaction was high in both groups. Both the calvaria and anterior iliac crest are associated with low long-term donor site morbidity and high patient satisfaction. Thus, patient-centred decision-making is appropriate when selecting the preferred harvesting method for that patient.

Multidisciplinary approach to oral rehabilitation with dental implants after gunshot injury: A clinical report

This clinical report describes a multidisciplinary approach to treat a patient with edentulism and a severe anatomic defect in the mandible caused by a gunshot injury by using an implant-fixed complete dental prosthesis. An immediate loading interim implant-fixed complete dental prosthesis in the mandible associated with a maxillary removable complete denture prosthesis was initially provided to restore the intermaxillary relation. Nasal floor elevation and maxillary sinus augmentation were subsequently performed to increase the maxillary bone volume. Definitive implant-fixed complete dental prostheses were placed in both arches in order to rehabilitate this initially compromised anatomic condition, which ensured patient satisfaction and improvement in masticatory function and esthetics.

Effect of exogenous retinoic acid on tooth movement and periodontium healing following tooth extraction in a rat model.

To evaluate the effect of isotretinoin on orthodontic tooth movement (OTM) and wound healing following exodontia. Sixteen 40-day-old male Wistar rats were divided into two groups: (a) OTM and (b) tooth extraction (TE) of the upper 1st molar and OTM. The experimental animals were treated with isotretinoin (7.5mg/kg) and the control animals with oil solution for 37days. The OTM and bone volume were evaluated by the micro-CT and the periodontium healing was assessed by immunohistochemistry for VEGF-C, COX-2 and IL-1ß. The animals of both groups submitted to the TE showed a statistically significant decrease in the bone volume percentage and increase in OTM. No significant difference of OTM and bone volume was observed between the control and experimental group. However, the alveolar bone of the isotretinoin group revealed more medullary spaces with inflammatory, hematopoietic cells, blood vessels and intense immunolabeling for VEGF-C. This group also showed faster gingival regeneration. No significant difference was observed in the COX-2 and IL-1ß labelings following TE between both groups. The isotretinoin did not affect the OTM nor did it cause an alteration in maxillary bone volume. This exogenous acid may contribute to the acceleration of gingival healing.

Maxillary involvement in hemifacial microsomia: an objective three-dimensional analysis of the craniofacial skeleton.

The aim of our study is to better understand the maxillary involvement in relation to the mandibular deformation in hemifacial microsomia (HFM). To do so, consecutive patients with HFM treated at The Children's Hospital of Philadelphia from 2000 to 2012 were included in our study. Both two-dimensional and three-dimensional analyses of the bony and sinus structures of the midface and mandible were performed using three-dimensional segmentation software. Patients were stratified into groups based on the Kaban-Pruzansky classification--mild (0-1), moderate (2A), and severe (2B-3)--as well as rank ordering based on overall severity. Analyses involved paired t-tests within severity groups, 1-way analysis of variance when assessing across groups (ipsilateral/contralateral ratio), and regression to assess for trends. Thirty patients were included (4 mild, 12 moderate, and 14 severe). The mandibular volume ratio differed across all patient groups (P < 0.001) and trended with rank order (P < 0.001). No significant difference in maxillary bony volume ratio was found across all patient groups (P = 0.16). In patients with severe disease, the maxillary bone volume was found to be significantly decreased on the ipsilateral side as compared with the contralateral side (P = 0.0123). There was no difference in maxillary sinus volume between ipsilateral and contralateral sides within any patient groups or in comparing across groups (P = 0.10). No significant trend was found in the volume ratio of mandible and maxilla (P = 0.41). To conclude, the maxillary sinus seems to show no difference in volume when comparing between laterality and severity groupings. These findings suggest that there may be alternative influences other than the vascular insult acting as the driving force behind the mandibular deformity and the additional classic clinical findings of HFM.

Changes in 3D Midfacial Parameters after Biomimetic Oral Appliance Therapy in Adults

Background/objectives/aims: Controversy exists regarding maxillary bone changes in nongrowing adults. However, previous studies have relied on two-dimensional (2D) cephalo metric analyses, which may be unable to capture three-dimen sional (3D) pheno mena. In this study, we investigated 2D and 3D parameters to test the null hypothesis that maxillary bone volume cannot be changed in nongrowing adults that had been diagnosed with mid facial underdevelopment. Methods: After obtaining informed consent, we undertook 3D cone beam computed tomography scans of 11 consecutive, adult patients prior to and after biomimetic, oral appliance therapy. The mean treatment time was 18.4 months ± 2.5 using the DNA appliance® system. The intramolar width and 3D volume of the midface was calculated prior to and after the mid facial redevelopment protocol. The findings were subjected to statistical analysis. Results: The mean intramolar increased from 33.5 mm ± 3.4 prior to treatment to 35.8 mm ± 2.9 after appliance therapy (p = 0.0003). Similarly, the mean midfacial bone volume was 17.4 cm3 ± 3.9 prior to treatment and increased to 19.1 cm3 ± 2.6 after appliance therapy (p = 0.0091). Conclusion: These data support the notion that maxillary bone width and volume can be changed in nongrowing adults. Furthermore, midfacial redevelopment may provide a potentially-use ful method of managing adults diagnosed with obstructive sleep apnea, using biomimetic, oral appliances.

Angled Dental Implant Placement into the Vomer/Nasal Crest of Atrophic Maxillae for All-on-Four Immediate Function: A 2-Year Clinical Study of 100 Consecutive Patients

To report on the use of angled implants placed into the vomer/nasal crest to support a complete-arch maxillary prosthesis. Consecutive patients were treated with the All-on-Four concept to restore the maxillary dentition. When bone volume in the subnasal region was inadequate, angled implants were placed into the vomer/nasal crest area to support the restoration. All implants were loaded immediately. One hundred consecutive maxillary All-on-Four patients were treated over a period of 2 years. Four hundred six implants were placed; 12 were inserted into the vomer/nasal crest area. One year later, at definitive restoration, the 12 vomer implants were found to be osseointegrated without bone loss or instability. Midline maxillary bone volume at the nasal crest appeared to be a viable alternative to the lateral nasal rim when subnasal bone was deficient. Vomer implants allowed for immediate function or were sometimes used as a rescue implant when an anterior implant failed.

Implant-Guided Volumetric Analysis of Edentulous Maxillary Bone With Cone-Beam Computerized Tomography Scan. Maxillary Sinus Pneumatization Classification

The primary goal of this anatomic study was to measure the average bone volume of the edentulous maxilla with a cone-beam computerized tomography (CBCT) scan and to determine its suitability for implant treatment without additional bone grafting. The secondary goal of the study was to estimate the degree of sinus pneumatization (SP) in reviewed CBCT scans, assess the sinus-to-maxillary bone interrelationship in edentulism, and attempt to classify maxillary sinuses based on the degree of their pneumatization. This retrospective radiographic quantitative study consisted of the analysis of CBCT scans of 30 randomly selected maxillary edentulous patients who presented in 2008-2010 to the University of the Pacific, Arthur A. Dugoni School of Dentistry, for evaluation and treatment of their edentulism. A volume of edentulous maxillary bone mesial to the maxillary sinuses (intersinal region) that can be used for a full-arch implant treatment was evaluated based on specifically selected and clinically relevant measurement criteria. There were 30 CBCT scans of maxillary edentulous patients reviewed (9 men, 21 women) with a mean age of 67.3 years (range, 41 to 92 years). The total mean maxillary bone volume (MMBV) suitable for implantation was 4 408.1 mm(3) and ranged from 1489.7 to 7263.1 mm(3). The MMBV in the study was higher than an assumed or hypothetical bone volume minimally suitable for 4-implant treatment as proposed by the authors for comparative purposes (3500 mm(3)). The degree of SP as seen on a CBCT scan (60 sinuses analyzed on panoramic images of 30 CBCT scans) had the following results in the study: SP0 (clear: not interfering with implant treatment in cases of high/small sinus), 2 sinuses or 3.3%; SP1 (mild sinus enlargement), 29 sinuses or 48.3%; SP2 (moderate SP), 16 sinuses or 26.7%; SP3 (severe SP), 9 sinuses or 15.0%; and SP4 (extreme), 4 sinuses or 6.7%. Most analyzed maxillary sinuses (47 of 60, or 78.3%) were in the clear, mild, or moderate categories of SP (SP0, SP1, and SP2), which have a sufficient amount of maxillary bone beneath the maxillary sinuses to allow a full-arch implant treatment. An inverse correlation between SP and MMBV was observed. Although many other clinical criteria are important (bone quality, alveolar crest anatomy, etc), the results of this CBCT radiographic study indicate that in many maxillary edentulous cases, the existing bone quantity (volume) can be sufficient for a full-arch maxillary implant treatment with at least 4 implants without the additional trauma or expense of bone grafts and sinus lifts. A variety of implant treatment options can be proposed based on maxillary bone availability and bone-to-sinus interrelationship. It appears that with age and edentulism, the amount of available maxillary bone is steadily decreasing.