Maturity Values Research Articles

Exciting Times are Ahead - Gaussian Views and Yield Curve Extrapolation

In the insurance industry, products having a much longer time to maturity and yield values for up to 100 years need to be modeled. J�rg Kienitz and Leenesh Moodliyar propose to apply Gaussian Process Regression (GPR) for the extrapolation. The method is compared to two market standard methods � the Nelson-Siegel-Svensson (NSS) and the Smith-Wilson (SW) methods

Circular Utilization of Coffee Grounds as a Bio-Nutrient through Microbial Transformation for Leafy Vegetables

This study explores the production of bio-nutrients from bioactive compound-rich spent coffee grounds (SCG) and biochar (BC) through composting after inoculation with a biological agent and its impact on the growth performance of garden cress and spinach. The SCG was composted with six doses of BC (0, 5, 10, 15, 20, and 25%). The compost with 10% BC exhibited the best maturity, humification, and phytotoxicity index values of dissolved organic carbon (DOC), humification index (E4/E6), and germination index (GI). A metagenome analysis showed that compost starter enhanced the bacterial community’s relative abundance, richness, and diversity in SCG and BC treatments. This improvement included increased Patescibacteria, which can break down noxious phenolic compounds found in SCG and BC. The BC enriched the compost with phosphorus and potassium while preserving the nitrogen. In plant growth experiments, the total chlorophyll content in compost-treated garden cress and spinach was 2.47 and 4.88 mg g−1, respectively, which was significantly greater (p ≤ 0.05) than in unfertilized plants and similar to the plants treated with traditional fertilizer. Overall, the results show that the compost of SCG + BC was well-suited for promoting the growth of garden cress and spinach, providing adequate nutrients as a fertilizer for these leafy vegetables.

Lamellar Body Count (LBC) in amniotic fluid for prediction of fetal lung maturity

Background: Neonatal respiratory distress syndrome (RDS) is a disorder due to pulmonary immaturity with a high mortality characterized by low levels of pulmonary surfactant. RDS is one of the important causes of mortality in neonates. Objective: The aim of the study is to determine the lamellar body count (LBC) cutoff value for foetal lung maturity and to evaluate the clinical usefulness of LBC in predicting the neonatal respiratory distress syndrome (RDS) and to find if the Measurement of LBC can replace the conventional Lecithin/Sphingomyelin ratio. Methods: This prospective observational study was performed on total 47 pregnant women divided as 19 patients with premature labor and 28 patients with healthy full-term singleton pregnancy as controls, with gestational age between 28 – 41 weeks at Ain Shams university maternity hospital in period between April 2014 and January 2015 with inclusion and exclusion criteria. Results: RDS was diagnosed in 20 neonates, two neonates in the 1st group (7.1%) While 18 neonates in 2nd (94.7%) showed development of RDS. Mean lamellar body count in newborns with RDS: 39,200 ± 12,438 with median 37,500 and p-value was <0.0001. ROC (receiver operator characteristics) curve showed that by using 51000/µL as a cut-off point for LBC it is a good predictor for fetal lung maturity with sensitivity 95% and specificity 96.3%. There is a direct relationship between the gestational age and the lamellar body count as the lamellar body count increases as long as the gestational age proceeds with a highly significant positive correlation (p value <0.0001). Conclusion: As evident from the current study, LBC count now replacing the conventional Lecithin/Sphingomyelin ratio because the test can be performed with equipment found in most clinical analysis laboratories and is reliable in predicting foetal lung maturity. This study suggests that LBC cutoff value of ≥51,000/µL can predict pulmonary maturity and reduce the risk of neonatal respiratory distress syndrome.

Source Rock Characteristics of Loa Janan Area, Kutai Kartanegara, East Kalimantan, Indonesia

The source rock analysis was involved examining the geochemical content of hydrocarbons in fine-grained sedimentary rocks. This study was conducted on claystone in the Loa Duri area to determine the source rock characterization, which includes the level of richness, the organic matter type, and the level of maturity. The methods used are field data collection and laboratory analysis. A field study is used to collect rock sampling, while laboratory analysis consists of the analysis of Total Organic Carbon content, Rock-Eval pyrolysis, and vitrinite reflectance (Ro). The results of the analysis of Total Organic Carbon on six claystone samples showed values ranging from 0.50-8.97%. Generally, they had the potential to form hydrocarbons in the moderate to special category. Rock-Eval pyrolysis shows Hydrogen Index values from 52–149 mg HC/g Total Organic Carbon has the potential to generate gas, with Tmax values ranging from 414–432, indicating an immature to early mature level of thermal maturity. Ro analysis on three claystone samples with values ranging from 0.40–0.48 %. The hydrocarbon potential of the research area indicates the category of organic material richness is quite excellent, with kerogen including type III. The quality of the source rock based on the value of the Hydrogen Index is included in the category of gas-prone. The low maturity value (both Tmax and Ro) is thought to be caused by the suppression phenomenon in coal-dominated areas, so the values displayed by the two parameters do not correspond to actual values.

Vaginal cytomorphological profile in correlating suicidal deaths in medicolegal autopsy cases

Objectives: Vaginal cytology is a sensitive method for assessing women’s hormonal status, showing variations in menstrual cycle phases. Studies suggest a higher rate of female suicides during the luteal phase. This study aimed to link vaginal cytomorphological profiles with the manner of death and age of the deceased. Materials and Methods: Vaginal smears from 64 autopsy cases were microscopically examined for maturation index (MI) and value, reflecting hormonal profiles. Statistical Analysis: ANOVA between the mean of maturation value with manner of death was found to be significant. Results: Among the 48 suicides, 54.2% showed predominantly intermediate cells in the luteal phase, indicating a mid-zone shift in the MI. The remaining 16 non-suicidal cases showed fewer intermediate cells. Suicides shared a similar cytological profile and MI, especially in the reproductive age group. Conclusions: While vaginal smears are typically used in sexual assault cases to detect sperm, they also offer insights into women’s hormonal profiles. Understanding these profiles could provide clues about psychological status and its relation to the manner of death beyond sexual assault.

Vermistabilization of excess sludge employing Eisenia fetida: Earthworm histopathological alterations and phytotoxicity evaluation

The aim of this work was to stabilize excess sludge (ES) coming from a wastewater treatment plant (WWTP) by vermistabilization and to evaluate ecotoxicological effects over the earthworm species Eisenia fetida. Three mixtures were made up in triplicate using different volume ratios of ES and soil (S) (100% ES, 70:30% ES:S and 30:70% ES:S in wet weight basis). Earthworms were added in order to compare vermicomposting vs. natural stabilization. The mixtures were monitored over 130 days through physical, chemical, pathological and biological analysis, following quality standards depicted in the US EPA 40 CFR Part 503, local regulations and background studies. Histopathological samples were processed as biomarkers of acute and chronic toxicity on earthworms, and germination assays were performed at the end of the experiment to assess phytotoxicity. In terms of pathogen depletion comparing initial and final values from each treatment, the mixtures with higher ES proportions (70 and 100%) with earthworms were the most efficient ones registering 64.8 and 75.5% of reduction of fecal coliforms (FC) respectively, while the lowest ES proportion with earthworms (30%) showed 54.7%. Final pathogens content in all the treatments with earthworms were significantly lower (ranged from 1360 to 1760 MPN g total solids−1) than the values registered in treatments without earthworms (ranged from 2400 to 4000 MPN g total solids−1) (p < 0.05). However, none of the treatments attained class A categorization (FC ≤ 1000 MPN g total solids−1) in terms of FC. Also, values of mean cocoon production and hatched juveniles along time were significantly higher in the treatments with 100 and 70% ES (p < 0.05), while the higher mean adult biomass was detected in the treatment with 30% ES. Volatile solids decrease ranged between 8.45 and 22.34% in treatments with earthworms and all values of specific oxygen uptake rate were below 1.5 mg O2 h -1 g total solids -1. There were not negative effects over behavior or reproduction of E. fetida adults, nor the presence of external and internal injuries. Final products from mixtures with earthworms presented a humus-like structure, were odorless and reached maturity values -presenting no phytotoxicity-with significant differences between germination index values of treatments with and without earthworms (p < 0.05). Vermistabilization is a successful eco-technology to sanitize excess sludge, acquiring an added-value material and contributing to its revalorization as organic amendments or fertilizers in soils within the circular economy framework and the United Nations’ Sustainability Development Goals.

Audit Sistem Informasi Monitoring dan Evaluasi (Monev) Pada Puskesmas Kecamatan Ciracas Menggunakan COBIT 2019

This research starts from the framework of thinking that auditing information technology governance in monitoring and evaluation (monev) information systems using COBIT 2019 is an important thing to do. In the present and future, it is necessary to align information technology investments with the aim of community services in public health centers. The COBIT 2019 framework provides the benefits of implementing information systems, minimizing risks, and optimizing resources according to needs at the Ciracas District Health Center. In implementing monitoring and evaluation (monev), the factor design from COBIT 2019 can determine which domains must be assessed for their maturity level, so that agencies can know what needs to be improved. In this case, the EDM02 domain focuses on the process of optimizing the contribution of business value, services and IT assets resulting from investment at a cost that is acceptable to the company, while MEA03 ensures that the agency has complied with all applicable external requirements. Based on the results of the inspection, EDM02 has a current maturity value of 4.23 with a maturity level of 5-Optimized, which means that the implementation of monitoring and evaluation (monev) at the Ciracas District Health Center has run according to its objectives, while MEA03 has a current maturity value of 3.98 with a maturity level of 4- Manged and Measureable, which means monitoring and evaluation (monev) at the Ciracas District Health Center has been running well, even data or information has been integrated

Assessment of the source rock potential in the Sirka and Giddi collieries of South Karanapura coalfield, Jharkhand, India: Insights from megaflora, palynology, and geochemistry

Permian deposits in the Indian Peninsula have long been a significant source of coal and have great potential for hydrocarbon exploration. Here we present results of megafloral, palynological, and geochemical analysis of the Late Artinskian-Kungurian sediments in the South Karanpura coalfield to assess hydrocarbon generation potential, kerogen types, depositional settings, and thermal maturation. The results suggest anoxic to oxic depositional environments with fluctuating water levels, influenced by terrestrial inputs. The Sirka colliery is considered to be most favorable for hydrocarbon generation due to the palaeodepositional setting dominated by flooded palaeomires. The dominance of degraded organic matter and the rarity of opaque phytoclasts suggest type II/III to type III kerogen material in the palaeomire of the Srika succession, characterized by low-energy dysoxic to anoxic conditions. The thermal maturation values (Tmax 429℃) and the production index (0.01–0.02) indicate that the Sirka area has immature kerogen, but the Giddi colliery has a relatively higher Tmax (average 435℃) placing the studied sample within the mature zone. However, due to deposition in the oxidized swamp, Giddi C has poor potential for hydrocarbon generation, showing that type III/IV material has charcoal input into the sediments. Our findings contribute to global knowledge of coal formations’ oil and gas storage capacity, which has implications for energy resource assessment and exploration strategies.

Impact of Solidago gigantea invasion on nematode communities in grasslands

Summary Solidago gigantea is one of the most problematic species of invasive plants in Europe, where its rapid spread threatens the stability of ecosystems. The effect of invasion by S. gigantea on soil ecosystems and food webs can be evaluated using nematode communities as suitable and useful soil bioindicators. We compared the effect of S. gigantea on nematode communities in plots invaded with S. gigantea and non-invaded grasslands across three sites with varying soil and climatic conditions. Our findings indicated that invasion by S. gigantea did not strongly affect nematode taxonomic diversity but negatively affected functional diversity. This effect was evident in the increased abundance of bacterivore and fungivore nematodes and decrease in values of ecological and functional indices. The evaluation of the soil food web using nematode communities confirmed that soil in plots with S. gigantea were less mature and more disturbed with a degraded or depleted food web indicated by lower values of maturity, enrichment and structure indices, compared with non-invaded grasslands. On the other hand, taxonomic diversity, abundance, biomass and the functional indices differed between three study sites, but site had little or no effect on the values of the maturity indices. The interaction between site and invasion status confirmed the effect of invasion on nematode biomass, with the abundance of bacterivore and fungivore nematodes and the functional indices more prominent at sites characterised by cold and humid climates. These findings underscore the importance of considering both taxonomic and functional diversity and the characteristics of the plants and sites when evaluating the impact of plant invasion on soil biota.

Life-history parameters of adult females of Merluccius capensis (Gadidae) off the south coast of South Africa.

This study explores the life-history parameters of female Merluccius capensis off South Africa (N = 1819) during 2014-2016, including gonadosomatic index (GSI), length-at-maturity, length-weight relationships, and condition indices (relative condition [k] and Fulton's condition factor [K]). We detected weak indications of two peaks of spawning within the year, the first in austral autumn from March to May, whereas the other in austral spring around August. GSI was slightly higher in spring and autumn, though still low at all maturity stages (≤7%), though the opposite was true for the actively spawning stage (≥7%) as well as access to less such data during winter- and summertime. The length (L) at 50% maturity was around 38 cm (L50), though differences occurred between the two applied staging methods, histology and visual (macroscopic) classification, when L approached infinity. The latter method presented underestimated length at maturity values at the 75 and 95 percentiles (48 and 60 cm) compared to the corresponding percentiles given by histology (50 and 65 cm). There were trivial across-method differences in L50. However, we found a clear reduction in L50 in view of published information in prior years when this estimate was 48 (1985), 42 (2008), 53 (2011), and 24.8 (2015) cm. Overall, L explained 90% of the variation in whole body weight (W). As the bootstrapped, grand mean growth coefficient was b = 2.98, indicating a slight allometric growth function, there were no significant variations between years, though an isometric growth existed for 2016 with b = 3.0, whereas for 2014 and 2015 this b was 2.98 and 2.93, respectively. In terms of demography, females <60 cm generally showed isometric growth (b = 3) as opposed to allometric growth (b = 2.95) at >60 cm. The relative condition index (k = 1) exhibited higher values than Fulton's K, which was 0.80. Overall, the maternal stock of M. capensis along the south coast seems to be in good condition and likely spawns throughout the year, but we found that the macroscopic data tend to give biased maturity ogives.

Industry 4.0 maturity model in the context of state of Espírito Santo

The aim of this paper is to develop a manufacturing maturity model for implementing Industry 4.0 technologies. The study was based on the methodology of De Bruin et al. (2005). The study contributes by providing insights into how the maturity model can help companies to see their strengths and weaknesses in order to improve the level of maturity of Industry 4.0 in these organizations. The model is specifically developed based on the specified objectives, factors and barriers, addressing the complexity of Industry 4.0 with a focus on manufacturing. To this end, a questionnaire was administered to 25 employees of companies in Espírito Santo, Brazil, with the aim of validating the model found and identifying the level of maturity of the organizations studied. The maturity model found consists of five maturity levels, three dimensions and 27 elements. The questionnaire applied resulted in a maturity level of 59.7%, obtaining an intermediate classification, meaning a partial use of Industry 4.0 technologies in the companies studied. A comparison was made between the Mining, Electrical, IT, Steel and Metallurgy sectors. The results showed that the Steel and Mining sectors have the highest maturity values and the IT and Metallurgy sectors have the lowest Industry 4.0 maturity values. A limitation of the study is the subjectivity inherent in the use of questionnaires. As a future suggestion, it is possible to identify the relationships between the elements presented in the maturity model.

Fractional and Microablative CO2 LASER and Radiofrequency in the Treatment of Genitourinary Syndrome of Menopause: A Descriptive Study.

Objectives: This study aimed to evaluate the vagina clinically, cytologically, and histologically before and after treating genitourinary syndrome of menopause (GSM) with fractional microablative carbon dioxide LASER (CO2L), radiofrequency (RF), and estrogen vaginal cream (CT). Methods: Women with moderate-to-severe symptoms of GSM, denoted by a GSM Visual analog scale (VAS) score of >4, were eligible for this study. The patients were randomized into treatment groups. In the energy groups, three vulvovaginal applications were administered monthly. The CT group used 0.5 mg vaginal estriol cream for 14 consecutive days, followed by twice a week for 4 months. The follow-up visits occurred 120 days after the beginning of the treatments. The same parameters obtained at the first visit were re-evaluated: GSM VAS score, Incontinence Quality of Life Questionnaire (I-QOL), gynecological examination determining Vaginal Health Index (VHI), vaginal smear for Vaginal Maturation Value (VMV), and vaginal biopsy. Results: Seventy-one women were included, 48 completed the study and provided adequate samples for analysis (CO2L [21 patients], RF [15 patients], and CT [12 patients]). GSM symptoms, I-QOL, and VHI significantly improved after all proposed treatments, with no significant differences between them. VMV did not change after any treatment; however, only 22.9% of the patients presented with cytological atrophy before treatment. Histological vaginal atrophy was identified in 6 (12.5%) pretreated vaginal samples. After the intervention, all histological parameters were normalized, no tissue damage was observed, and no major clinical complications were observed. Conclusion: CO2L and RF seem to be good alternatives to CT for GSM treatment, with no tissue damage.

#1476 Impact of frailty on maturation of native arteriovenous fistula in patients with end-stage kidney disease

Abstract Background and Aims Morbimortality and quality of life in hemodialysis patients is directly related to the reliability and integrity of the vascular access. Current guidelines recommend a shift from a "fistula first" approach to a patient-centered approach due to the aging dialysis population. Frailty, defined as vulnerability to adverse health states due to impaired functional status, comorbidities and psychosocial factors, conditions a worse outcome of patients with end-stage kidney disease (ESKD) undergoing dialysis. Our aim was to assess frailty status before the performance of native arteriovenous fistulas (nAVF) as a predictor of failure to mature. Method Retrospective analysis of ESKD clinic patients who underwent a first nAVF between 2020-2022 and had undergone a frailty assessment before the surgery. The Frail-VIG index, evaluating frailty through deficit accumulation (scored from 0 to 1), vas employed. Patients were categorized as either non-frail (NF-ESKD: Frail-VIG &amp;lt; 0.2) or frail (F-ESKD: Frail-VIG ≥ 0.2). the study evaluated early nAVF and recorded the first ultrasound maturation values 4 weeks after surgery. Results Throughout the study period, 180 patients underwent a first nAVF, 57 (31.6%) having undergone a prior frailty assessment. 27 (47.4%) patients were classified as NF-ESKD, 30 (52.6%) as F-ESKD (23 mild, 6 moderate and 1 severe frailty). In the descriptive analysis, no differences in age, sex, toxic habits, CKD etiology or medical conditions were observed between the two groups (Table 1). Regarding surgical technique, there were no differences in nAVF location and laterality between the two groups (Table 1). F-ESKD patients had a higher primary fistula failure, defined as no flow prior to the first ultrasound evaluation (36.7% vs. 3.8%; p=0.002). In patients with an initial ultrasound evaluation, the F-ESKD group had lower arterial flow (1020.76 ± 589.42 vs. 1455.56 ± 679.78 ml/min; p=0.027) and smaller fistula diameter (4.52 ± 1.51 vs. 6.4 ± 1.61 mm; p=0.018). Maturation was assessed after the first ultrasound evaluation, defined as the presence of an arterial flow greater than 500 ml/min and a diameter greater than 4 mm. A higher proportion of frail patients (88.9% vs. 33.11%; p = 0.004), a lower capacity to perform instrumental activities measured by Lawton Brody index (4.63 ± 2.2 vs. 6.55 ± 2.2; p = 0.034) and a higher percentage of diabetic patients (88.89% vs. 48.48%; p = 0.033) were found in nAVF that had not reached ultrasound-guided maturity (Table 2). In a multivariate analysis adjusted for functional status, type of vascular access and comorbidities, the presence of frailty conferred a higher risk of fistula non-maturation (OR 11.42 95%CI 1.005 - 128.74; p = 0.049). Conclusion The prevalence of frailty is notable among in ESKD patients and contributes to a higher rate of failure in native nAVF. Within this population, adopting an individual approach to the selection of a definitive vascular access may prove both feasible and beneficial in ensuring optimal dialysis access.

Benzocarbazole and methylxanthone molecular migration tracers unravel migration routes and filling history of Veslefrikk, Oseberg-East and Brage reservoirs in the Norwegian North Sea

Identification of petroleum migration routes and reservoir filling processes is feasible by applying carbazoles or xanthones as molecular migration tracers. To verify their utility, a well-constrained migration route was chosen for this study: the petroleum migration along the Veslefrikk and Oseberg East fields until reaching the Statfjord Formation compartment within the Brage field in the Norwegian North Sea. This migration route comprises an ideal test case because the oil is sourced from the same kitchen area, yielding very similar oil families in all three fields, and because the maturity remains within the main oil window, below 0.9 Ro % vitrinite reflectance equivalence.Different methodologies applied by two laboratories, from sample preparation to analytical methods, yielded identical results of migration direction and route using the benzocarbazole ratio ([a]/([a]+[c]), thus underlining practicability and robustness of this molecular migration parameter. The benzocarbazole ratio (BCR) in this study was neither affected by source rock facies, and/or biodegradation. A thermal maturity effect on BCR is considered here to be of only subordinate impact whereas it substantially affects benzocarbazole concentrations. The BCR declined from values of 0.68 at onset of migration to 0.42 at end of migration, whereby the absolute concentrations of benzocarbazoles in parallel declined by a factor of 10, from 5000 to 500 ng/g oil. The distribution and concentration of methylxanthones evolved comparable to that of benzocarbazoles. The methylxanthones ratios (MXR) from onset of migration until reaching the Brage field declined from a value of 0.85 to 0.42. The benzocarbazoles and methylxanthones, like other geo/biomarkers, preferentially reflect the first charge of the most polar and least mature oil delivered upon petroleum migration and could help to understand the reservoir filling history.Migrating oils derived from the Sogn Graben kitchen entered the Veslefrikk oil field first and continued until the structure was filled to spill point. Thereafter, migration continued to the Oseberg East oil field and after reaching spill point there it continued to the Brage field and its Statfjord formation compartment. The complex migration route represents a classical fill to spill scenario and benzocarbazole fractionation upon migration delineates the initial filling trends. The maturity values of crude oils are in the mid-oil window and show trends of covariance with the molecular migration indicators, thus proving to be supporting tracers in a classical fill to spill scenario, where maturity values are lowest when migration distances are greatest. This is due to the first expelled oil being of lowest thermal maturity entering the nearest reservoir first and then being displaced into farther reservoirs along the migration route upon arrival of later oil (more mature) charges.

Morphological changes in the liver of bulls after the use of adaptogens

The paper presents the results of a study of the influence of adaptogens of plant and animal nature on the productive qualities of Kazakh white-headed bulls and morphological changes in their liver. 40 6-month-old beef bulls were selected for the study, which were divided into 4 groups: I (control) group of bulls consumed only the basic diet, II — adaptogen leucea safflower, III — drone homogenate, IV — pantocrine at the rate of 0.01 ml per 1 kg of animal body weight. At 18 months, a control slaughter of 3 animals from each group was carried out. During the experiment, it was found that the mass of the paired carcass in the bulls of the experimental groups increased by 11.1–21.7 kg (4.25–8.31%, р ≤ 0.05), the slaughter weight by 11.7–23.0 kg (4.24–8.34%, р ≤ 0.05–0.01), the slaughter yield by 0.9–1.9%. The analysis of the morphological composition of the carcass indicates an increase in the specific weight of its edible part of the carcass: by weight of muscle tissue by 4.0–7.7 kg (4.66–8.97%, р ≤ 0.05–0.01), fat — by 0.7–1.4 kg (4.67–9.33%, р ≤ 0.05). There is a high degree of maturity and high nutritional value of the meat of bulls of the experimental groups. Histological studies of the liver of bull calves indicate that when using tincture from drones, the liver structure corresponds to the norm, while in the control group animals some signs of dystrophic changes without pronounced infiltrations and signs of stagnation were found.

Petrography and Heavy Minerals as Tools for Provenance Identification of the Injana Sandstone (Upper Miocene), Al-Habbaniyah City, Anbar Governorate, Iraq

This study deals with the petrography and heavy mineral analysis of the Injana sandstone at Al-Habbaniyah City. Thirteen samples are collected from the Injana Formation. A petrographic study is achieved on ten samples while all samples are analyzed for heavy minerals. The petrographic analysis showed that the common components of the Injana sandstone are rock fragments, especially sedimentary fragments. Quartz grains (monocrystalline and polycrystalline) and feldspars (k-feldspar and plagioclase), bounded by matrix and carbonate cement. The suggested provenance for the Injana Formation is mainly sedimentary and igneous sources and the less dominant metamorphic source. These sandstones are considered to be mineralogically submature-immature and classified as litharenites. Heavy minerals analysis showed two sets of minerals including opaque and transparent minerals, the opaque minerals are significant components of the heavy mineral assemblages, then chlorite, epidotes, amphiboles, garnet, pyroxenes (ortho and clino), zircon, tourmaline, biotite, muscovite, rutile, and others. This assemblage implies that the dense minerals are typically found in basic igneous and metamorphic rocks, with less frequent occurrences in acidic igneous and reworked sediments. According to QLF and QmFLt classifications, the tectonic provenance of the Injana sandstone is described as recycled orogen. The MF-MT-GM classification showed that the sandstone of Injana is derived primarily from active continental margins. The result of maturity MI and ZTR revealed low values of maturity, the MI value ranges between 0.6 to 1.5 with an average of 0.9 and ZTR Maturity ranges between 0.7% and 9% with an average of 3.9%, these low values of maturity indicate sub-mature to immature sandstone.

Prediction of body mass index and skeletal maturity for early menarche risk at menarche onset: a cross-sectional study of Chinese girls

BackgroundThis study aimed to assess the predictive value of body mass index (BMI) and skeletal maturity for the occurrence of early menarche in Chinese girls.MethodsA cross-sectional analysis was conducted on...

Characterization and Crystallinity of Two Bioactive Sealers: Qualitative and Quantitative Analysis

Since the crystallinity of hydroxyapatite created by bioactive sealers could affect their solubility percentage, this study aimed to analyze the degree of crystallinity and mineral maturity of hydroxyapatite crystals formed by bioactive (Cerafil and Endosequence) root canal sealers. Set discs of each sealer were submerged, either in deionized water or phosphate buffer solution (PBS). After 30 days, the crystallinity indices, crystal size, and mineral maturity were determined. The data were statistically analyzed using ANOVA and Student’s t tests with significance set at p &lt; 0.05. After immersion in PBS, Endosequence had the most significant value of mineral maturity (1030/1110Raman) and PO4/amide IFTIR ratio. However, the CO3/PO4 ratio was reduced by both solutions, particularly by PBS. There was no significant difference between both bioactive sealers. Compared to Endosequence, Cerafil had the highest crystallinity indices for CIXRD, CIFTIR, and CIRaman. AH-26 had a significantly greater crystal size (p &lt; 0.001). There was no significant difference in the crystal size of the Cerafil and Endosequence bioactive sealers (p &gt; 0.05). Overall, Cerafil and Endosequence successfully formed hydroxyapatite crystals when exposed to PBS, with high CIs obtained by Cerafil. The crystallinity and mineral maturity of Cerafil and Endosequence were comparable. On the other hand, AH-26 failed to produce hydroxyapatite.

GnRHr, LHr, and Vg gene expression levels and ovarian development of G5 transgenic mutiara female catfish (Clarias gariepinus) after exposure photoperiod induction

This study aimed to determine the relative expression ratios of the genes gonadotrophin-releasing hormone receptor (GnRHr), luteinizing hormone receptor (LHr), vitellogenin (Vg) and β-actin genes as expression control internal of the G5 fish using real-time PCR in a photoperiod experiment with designed treatments (A: 8L-16D; B: 12L-12D; C: 16L-8D for transgenic fish; and A*: 8L-16D; B*: 12L-12D; C*: 16L-8D for nontransgenic fish) for 60 days of rearing period. Ovary maturation was evaluated in G5 transgenic mutiara catfish during different photoperiod induction. A short photoperiod (8L-16D) induced an high expression of GnRHr, LHr, and Vg genes (mean, 4.42 ± 0.53, 5.63 ± 0.42, and 6.67 ± 0.31, respectively), indicating the role of dark cycle in increasing the gene expressions involved in ovarian maturation of G5 transgenic mutiara catfish. The lowest GnRHr, LHr, and Vg gene expression levels were found in nontransgenic fish (C*) (mean, 1.27 ± 0.13, 1.38 ± 0.24, and 2.42 ± 0.33, respectively). The exposure of transgenic fish (CgGH insert content) to a long photoperiod (16L-8D) resulted in lower expression levels of GnRHr, LHr, and Vg (mean, 2.31 ± 0.27, 2.34 ± 0.25, and 4.49 ± 0.30, respectively) and lower levels of hormones Vg and E2 (mean, 295.16 ± 21.71 μg/mL and 0.25 ± 0.03 ng/mL, respectively) and in non-transgenic fish (mean, 163.54 µg/mL and 0.14 ng/mL, respectively). Short photoperiods (8L-16D and 12l-12D) led to oocyte maturation and higher GSI values (mean, 12.24 ± 0.53 and 10.24 ± 0.38, respectively) compared to long photoperiods (16L-8D). Conversely, a long photoperiod led to decreased GnRHr, LHr, and Vg expression levels, and Vg and E2 hormone levels, leading to the growth of immature oocytes and decreased GSI (mean, 3.93 ± 0.29) in nontransgenic fish. The presence of CgGH in G5 transgenic mutiara female catfish can maintain the growth of primary oocytes to secondary oocytes during the 16L-8D photoperiod induction.

Genome-wide genetic architecture for plant maturity and drought tolerance in diploid potatoes.

Cultivated potato (Solanum tuberosum) is known to be highly susceptible to drought. With climate change and its frequent episodes of drought, potato growers will face increased challenges to achieving their yield goals. Currently, a high proportion of untapped potato germplasm remains within the diploid potato relatives, and the genetic architecture of the drought tolerance and maturity traits of diploid potatoes is still unknown. As such, a panel of 384 ethyl methanesulfonate-mutagenized diploid potato clones were evaluated for drought tolerance and plant maturity under field conditions. Genome-wide association studies (GWAS) were conducted to dissect the genetic architecture of the traits. The results obtained from the genetic structure analysis of the panel showed five main groups and seven subgroups. Using the Genome Association and Prediction Integrated Tool-mixed linear model GWAS statistical model, 34 and 17 significant quantitative trait nucleotides (QTNs) were found associated with maturity and drought traits, respectively. Chromosome 5 carried most of the QTNs, some of which were also detected by using the restricted two-stage multi-locus multi-allele-GWAS haploblock-based model, and two QTNs were found to be pleiotropic for both maturity and drought traits. Using the non-parametric U-test, one and three QTNs, with 5.13%-7.4% phenotypic variations explained, showed favorable allelic effects that increase the maturity and drought trait values. The quantitaive trait loci (QTLs)/QTNs associated with maturity and drought trait were found co-located in narrow (0.5-1kb) genomic regions with 56 candidate genes playing roles in plant development and senescence and in abiotic stress responses. A total of 127 potato clones were found to be late maturing and tolerant to drought, while nine were early to moderate-late maturing and tolerant to drought. Taken together, the data show that the studied germplasm panel and the identified candidate genes are prime genetic resources for breeders and biologists in conventional breeding and targeted gene editing as climate adaptation tools.