The phenomenon of aphasia in Chinese culture is serious. The existing English teaching materials emphasize too much Western culture education and lack traditional Chinese cultural elements. Therefore, this paper takes the Guangdong Maritime Silk Road as an example to study the specific application of traditional Chinese culture in cross-cultural English education. This paper first summarizes the significance of cross-cultural integration into college English education and then points out the serious phenomenon of Chinese cultural aphasia. Next, the paper focuses on English education, using English textbooks as a starting point to explore and integrate strategies related to excellent traditional Chinese culture from the Guangdong Maritime Silk Road. By integrating traditional Chinese culture into business English classes (with the Guangdong Maritime Silk Road as an example), the study explores the influence of such cultural integration on students’ cross-cultural communication skills, cultural identity, and learning effects. The results showed that the P value of the experimental group and the control group was < 0.05, that is, cultural integration had a positive effect on improving the effect of cross-cultural English education. The overall scores and cultural confidence of the experimental group are higher than those of the control group, which proves that cross-cultural teaching has a positive effect on the improvement of students’ scores.