The specific objectives of this study are two-fold: (i) to examine the impact of cultural facets of the Arab Middle East region on long-term manufacturer-supplier relationships (LTR) and (ii) to uncover the ways trust functions as a moderator (facilitating or hindering) of the relationships. Prior research examining manufacturer-supplier relationships has largely focused on cross-country and macro-regional inter-firm relationships in Western cultural contexts, while research on the national cultural effects on LTR in non-Western cultural contexts is sparse. We test the effect of six Arab cultural values: Ta’arof (meeting someone, تعارف), Wasta (who you know, واسطة), Wa’ad (promise, وعد), HifzMa’aWajh (saving face, حفظ ماء الوجه), Qada-Qadar (fatalism, القضاء والقدر), and Shura (consultative, شورى). Data from 302 matched manufacturer-supplier dyads in the Jordanian manufacturing sector are used to analyse the hypothesised relationships through a partial least square structural equation modelling (PLS-SEM) and multi-group (PLS-MGA) analysis. Our study supports the general consensus of the need to consider cultural and trust issues in building LTR. The PLS path estimates provides support for all hypotheses except for the impact of ta’arof (meeting someone تعارف-) on LTR. The PLS-MGA moderation analysis shows that the moderating role of theqa (i.e. trustثقة-) on LTR varies between different cultural norms and between manufacturers and suppliers. The findings contribute to the increasing shift of focus towards macro-organisational research and beyond Western-derived cross-cultural paradigm to account for context-specific cultural effects of developing societies on LTR.