Manifestations Of Schistosomiasis Research Articles

Schistosomal (bilharzial) polyps: Travel through the colon and beyond.

Schistosomiasis (bilharziasis) is a major neglected tropical disease. It is endemic in many tropical and subtropical communities. Schistosomal polyps (S. polyps) are not uncommon presentation of this infection. Although the colon is the most commonly affected organ, many other organs are affected. S. polyps are associated with a variable range of morbidity independent of the Schistosomal infection. S. polyps are frequently described in endemic areas and increasingly reported in non-endemic areas mainly among immigrants and visitors to the endemic areas. This review aimed to increase awareness of practitioners, especially gastroenterologists, for this peculiar type of polyps caused by this neglected infection hence improving patient outcomes. Web-based search of different databases was conducted for the literature focusing the development of S. polyps in the colon and other organs with analysis of the clinical manifestations, diagnosis and treatment. The following key words were used in the search, "Schistosomiasis" OR "Bilharziasis" AND "Polyps" OR "Polyp" AND "Colon" OR "Small intestine" OR " Duodenum" OR " Stomach" OR "Esophagus" OR " Gallbladder" OR" Pharynx" OR "Larynx" OR "Trachea" OR "Urinary bladder" OR " Ureter" OR "Renal Pelvis" OR "Urethra". All publication types including case reports, case series, original research, and review articles were retrieved and analyzed. S. polyps are not infrequent presentation of acute or chronic Schistosomal infection. S. polyps are described in many organs including the bowel, genitourinary tract, skin, gallbladder and the larynx. Presentation of S. polyps is variable and depends on the site, number as well as the polyp size. The relationship of S. polyps to malignant transformation is a matter of discussion. Presence of S. polyps is sometimes the only manifestation of Schistosomiasis. Small polyps can be treated medically with praziquantel, while large accessible polyps are amendable for endoscopic excision through different polyp resection techniques. However, huge, complicated, non-accessible and suspicious polyps are indicated for surgical management or advanced endoscopic resection when appropriate. Clinicians and endoscopists should be aware about these facts when treating patients living in, immigrated from or visiting endemic areas.

Schistosomiasis mansoni in families of fishing workers of endemic area of Alagoas

Abstract Objective: To analyze the epidemiological and clinical aspects involved in the transmission and manifestation of schistosomiasis in a community of fishermen from the endemic area of Alagoas. Methods: Epidemiological, transversal, prospective, descriptive, quantitative study. The coproparasitological survey included 275 family units of fish workers and the epidemiological and clinical ones, those with a positive diagnosis for S. mansoni. Results: The prevalence of schistosomiasis was 13.9% (fishermen), 2.1% (shellfish) and 2.1% (family members). The occurrence of the infection varied according to gender, age, ethnicity and socioeconomic status. Exposure occurred near the home. Autochthonous and predominant low parasite burden, intestinal clinical presentation, abdominal pain and diarrhea were observed. There were no nutritional and pressure changes associated with parasitosis. Adherence to drug therapy and use of the schistosomicidal drug was feared. Conclusion: Fish workers are at high risk for contracting the disease with clinical hepatointestinal manifestation, which requires more intense health actions.

Schistosomiasis: Diagnosis, Prevention, Treatment

Background: Human schistosomiasis is a parasitic disease caused by blood-worms that infect multiple organs, including the liver, intestine, bladder, and urethra. This disease may be eliminated with praziquantel, vaccines, and gene therapy. Aims: In this review, the author describes the progress in a study of schistosomiasis that focused on the life cycle, diagnosis, and control. Methodology: The author searched the PubMed Database at NCBI for articles on schistosomiasis published between 2014 and 2018. All articles were open access and in English. Results: The life cycle of this parasites involve two hosts: snails and mammals. Manifestations of schistosomiasis can be acute or chronic. Clinical manifestations of acute schistosomiasis can include fever and headache. Symptoms of chronic infections can include dysuria and hyperplasia. Infection can occur in several sites including the bile ducts, intestine, and bladder. The different sites of infection and symptoms seen are related to which of the species involved. Five species can infect humans. The three most commons are S. haematobium, S. japonicum, and S. mansoni. Detection tools for people with schistosomiasis can include the Kato-Katz and PCR. Praziquantel is at present the only effective treatment of this disease. In the future, vaccination or gene therapy may be used. Conclusion: Kato-Katz and PCR are tools for detecting schistosomiasis on humans. Praziquantel, diagnosis, vaccines, and gene therapy are useful methods for eliminating schistosomiasis.

Perianal lesions after return from Togo: An isolated cutaneous manifestation of schistosomiasis

Isolated perianal lesions in a returned traveller from Togo were observed. Eosinophilia was the lead to schistosomiasis, although no systemic symptoms were reported. This case report of cutaneous schistosomiasis demonstrates the importance of a travel history, especially geographic and exposure features, and treats the differential diagnosis of eosinophilia in a returned traveller with skin lesions.

Urinary Schistosomiasis: A Report of Four Cases and a Review

Urinary schistosomiasis is a common cause of hematuria in tropical regions, where it most often affects teenage boys. Children presenting with hematuria in the developed world are usually considered to have bacterial cystitis or a structural lesion and are investigated and treated accordingly. The authors report on a family recently returned to Canada from Nigeria in which all four children had urinary schistosomiasis. Nocturnal enuresis was the presenting symptom in the index case; this patient also had hematuria and dysuria. Nocturia occurred in a second child, and the other two children were asymptomatic. All four were cured by a single dose of praziquantel, a new schistosomicide. The life cycle of the causative organism, the clinical manifestations of schistosomiasis, the host response and treatment with praziquantel are reviewed.

A clinico-epidemiological survey of schistosomiasis mansoni in a hyperendemic area in Minas Gerais State (Comercinho, Brazil). I. Differences in the manifestations of schistosomiasis in the town centre and in the environs

A cross-sectional survey of schistosomiasis was done in Comercinho (Minas Gerais State, Brazil). Faecal (Kato-Katz technique) and physical examinations were performed on 90% and 79% of the population (1474 inhabitants), respectively. The rate of infection with Schistosoma mansoni was 70%, the geometric mean of eggs was 334/g of faeces and 7% of the infected individuals had splenomegaly. The rate of infection, faecal egg counts and the rate of splenomegaly were significantly higher in the environs (zones 3 and 4) of the town than in the central areas (zones 1 and 2) of Comercinho. This difference seemed to be determined by the social differences existing between the population in the central area and the environs; in the environs the heads of families were predominantly manual workers (73 and 94% respectively), only 10 and 3% of the houses had piped water supply and less than 14% were of better quality.

A stochastic model for the analysis of age-specific prevalence curves in schistosomiasis

INTRODUCTION IN AN attempt to gain further knowledge into the mechanisms involved in a disease it is often useful to construct a model which describes in mathematical form the essential features of the disease process. To date several models have been presented which deal with various aspects of schistosomiasis and their scope ranges from describing the entire cycle of the disease (given by Macdonald [l], Coffman and Warren [Z], Hairston [3], and Nasell and Hirsch [4]) to describing specific aspects of the disease in the human host (given by Hairston [S] and Tallis and Leyton [6]). The model presented in this paper focuses attention on the manifestation of schistosomiasis in the human host. In this development we consider the following essential features of the lifecycle: (i) the entry of the parasite into the host, (ii) the pairing of female and male parasites, (iii) the shedding of eggs by the host infected with schistosome pairs, and (iv) the death of the parasite within the host. The model we develop for the frequency distribution of the size of the population of worms within the host is the immigration-death process, and we illustrate how this model might be used to describe the mathematical form of the age--specific prevalence curves for schistosomiasis.

Comparative studies on the characteristics of some geographical strains of Schistosoma mansoni in mice and hamsters.

In the First Report of the W. H. O. Expert Committee on Bilharziasis (1953) it was stated: “Infection with Schistosoma is often well tolerated and without clinical signs, however this relative benignity appears to vary considerably from country to country, without the cause of these variations being as yet thoroughly understood”. This statement refers to the relative absence of serious manifestations of schistosomiasis as has been reported by various investigators working in Africa, e.g. Ramsay (1934) working in Nigeria, Dixon (1934) and Fisher (1934) in the Congo, Gelfand (1950) in Southern Rhodesia, Mackey (1953) in Tanganyika, Manson-Bahr (1958) in Kenya and Nelson (1959) in Uganda as compared with the situation reported in Egypt and South America.