Weight Management Control Research Articles

Effects of Indigenous Saudi Herbals on Weight Control in High Fat Diet-fed STZ Induced Diabetic Rats

Introduction: Obesity, a critical global issue, involves the accumulation of excessive body fat, elevating the risk of diabetes, hypertension, and other severe health conditions. This widespread concern is particularly pronounced in nations like Saudi Arabia, demanding urgent and efficient management approaches. Addressing weight control necessitates comprehensive interventions encompassing education, dietary modifications, and increased physical activity. By following healthier lifestyles and fostering a supportive environment, improvement can be made on healthcare systems. Collaboration between governments, healthcare professionals, and communities is pivotal to reduce obesity's impact and fostering a healthier generations.
 Methods: Research Design and Objectives: This study aimed to fill the existing void in excessive body weight treatments by investigating viable herbal interventions that are safe, readily accessible, and economically viable. Wistar albino rats were grouped to 5 groups with 5 animals each. Diabetics were induced by intraperitoneal injection of streptozotocin for all groups except group 1. Then respective groups were fed with fat diets for 12 weeks and herbals Zingiber officinale (ginger), Nigella sativa (black seeds) and Allium sativum (Garlic) from 7th to 12th weeks along with high fat diet. Mean Body weight and Lee's obesity index were calculated for each group.
 Results and Discussion: In the realm of herbal efficacy, a striking trend surfaces. Among the diverse materials scrutinized, one distinct name rises—Garlic (Allium sativum). Its prowess in diminishing both body weight and fat content stands out prominently. Across the tested spectrum, a consistent and impressive reduction in weight prevails. Particularly, Garlic asserts its dominance as a singularly remarkable performer, showcasing unparalleled effectiveness. This herbal gem not only underscores its potency but also solidifies its position as a preeminent agent for weight and fat reduction. The findings unequivocally spotlight Garlic's exceptional role in promoting healthier body composition.
 Conclusions: Herbals as Adjunctive Therapy for Obesity The findings underscore the potential of herbal interventions, particularly Garlic, in the management of weight control. These natural remedies hold promise as adjunctive therapeutic agents. However, further rigorous human trials and animal studies with large sample size and different methodology are essential to validate their efficacy and integration into obesity / weight control treatment regimens.

Energy assessment of some nuts and dried fruits grown in Pakistan’s climate and their role for weight control management

The aim of the present study is to assess the energy contents of different dry fruits consumed in Pakistan. Six samples of tree nuts (walnut, almond, pine nut, pistachio, cashew nut, and coconut), one sample of the ground nut (peanut), and four samples of dried fruits (figs, apricot, dates, and raisins) were selected for this purpose. The energy contents of nuts and dried fruits were estimated using oxygen bomb calorimeter. Peanut was identified as the energy rich fruit (875.86 Cal/100g), followed by walnut (818.84 Cal/100g), coconut (787.36 Cal/100g), almond (785.61 Cal/100g), pine nut (772.31 Cal/100g), Pistachio (624.72 Cal/100g), and the cashew nut (616.46 Cal/100g). The energy values of the dry fruits were found higher in nuts (875.86-616.46 Cal/100g), compare to dried fruits (352.04–505.31 Cal/100g). Protein and fats contribute to the energy values of nuts; while carbohydrates make a valuable contribution to the energy content of dried fruits. The recommended serving of dry fruits was found to fulfill 20.26−4.40 % of the minimum estimated energy requirement (EER) of persons of different life styles. On the basis of the caloric content of the studied dry fruits, one can easily calculate the required amount of a particular dry fruit per day in accordance to gender, age and PAL life style. Therefore, the study would be helpful to plan weight balance strategies for individuals interested in energy dense food.

Short-term changes in dietary fat levels and starch sources affect weight management, glucose and lipid metabolism, and gut microbiota in adult cats.

A 2 × 2 factorial randomized design was utilized to investigate the effects of fat level (8% or 16% fat on a fed basis) and starch source (pea starch or corn starch) on body weight, glycolipid metabolism, hematology, and fecal microbiota in cats. The study lasted for 28 d and included a low fat and pea starch diet (LFPS), a high fat and pea starch diet, a low fat and corn starch diet, and a high fat and corn starch diet. In this study, hematological analysis showed that all cats were healthy. The apparent total tract digestibility of gross energy, crude protein, and crude fat was above 85% in the four diets. After 28 d, cats fed the high fat diets (HF) gained an average of 50 g more than those fed the low fat diets (LF). The hematological results showed that the HF diets increased the body inflammation in cats, while the LFPS group improved the glucolipid metabolism. The levels of glucose and insulin were lower in cats fed the LF diets than those in cats fed the HF diets (P < 0.05). Meanwhile, compared with the LF, the concentrations of total cholesterol, triglyceride, and high-density lipoprotein cholesterol in serum were greater in the cats fed the HF diets (P < 0.05). Additionally, both fat level and starch source influenced the fecal microbiota, with the relative abundance of beneficial bacteria, such as Blautia being significantly greater in the LFPS group than in the other three groups (P < 0.05). Reducing energy density and using pea starch in foods are both valuable design additions to aid in the management of weight control and improve gut health in cats. This study highlights the importance of fat level and starch in weight management in cats.

Weight Management for Students with Attention-Deficit Hyperactivity Disorder (ADHD): A Qualitative Study.

(1) Background: Individuals with Attention-Deficit Hyperactivity Disorder (ADHD) are more likely to respond with an ineffective coping behavior, combined with an increased risk of weight gain and unhealthy food consumption. The aim of the study was to examine coping strategies adopted by overweight adults with ADHD to promote healthy behaviors and weight-control management. (2) Methods: Descriptive qualitative research using semi-structured interviews analyzed through a thematic content-analysis approach. The study included 30 college students diagnosed with ADHD, with a BMI ≥25.5, who had lost ≥10 kg within at least one year and successfully maintained that weight for the past three years. (3) Results: The study yielded two main themes. The first is struggling with disappointments and negative feelings in the past, and the second is the reciprocity between weight management and coping skills strategies. The second theme includes three subthemes-cognitive strategies, behavioral strategies, and emotional strategies. (4) Conclusions: It is essential to understand the variety of coping strategies used by adults to cope with ADHD challenges that can potentially improve weight control management and healthy behaviors to design better, more accurate interventions, promoting the target population's well-being and health.

Association of body perception and dietary weight management behaviours among children and adolescents aged 6\u201317\xa0years in China: cross-sectional study using CHNS (2015)

BackgroundObesity is rapidly globally increasing. Meanwhile, there is an increase in negative perception of the body image and, consequently, an increase in weight control management. Body perception plays an important mediating role between overweight or obesity and weight control behaviours. This study aims to examine whether body perception is associated with dietary weight management behaviours among Chinese children and adolescents.MethodsChild body perception and health behaviours from Chinese Health and Nutrition Survey (2015) were assessed, and 729 boys and 640 girls who aged 6 to 17 years were included in this study. Variables assessed as covariates were sociodemographic, physical activity and body perception involving self-perceptive weight status and body image dissatisfaction (BID). Multivariate logistic regression was used to explore the association between dietary weight management behaviours and body perception.Results60.77% students rightly matched their body mass index (BMI) with self-perceived weight. The prevalence of BID was 59.39%. After adjustment for sociodemographic information, physical activities and BMI, those whose self-perceived weight status as overweight/obesity were associated with an increased risk of dietary weight management behaviours comparing to those who have normal weight in boys (OR = 5.07; 95% CI = 1.86, 13.87; P < 0.001) and girls (OR = 14.28; 95%CI = 5.73, 35.56; P < 0.001). And those who desire to be thinner were strongly associated with dietary weight management behaviours (OR = 9.51; 95%CI = 3.47, 26.09; P < 0.001) comparing to those who were satisfied with their body image in girls.ConclusionsThe results revealed that body perception had a significant association with dietary weight management behaviours and exited the discrepancy according to sex. It is necessary to promote healthy awareness of body perception and to establish self-motivation for improving basic health knowledge in school health education activities.

Lowered Fasting Blood Glucose (FBG) in a Prediabetic Individual with HIV Despite Struggle with Weight Control Management- CASE STUDY (FS17-06-19)

ObjectivesHIV infection has previously been associated with malnutrition and wasting; however, with the initiation of antiretroviral therapy (ART), a growing number of people living with HIV (PLWH) are becoming centrally obese, with disproportionate weight accumulation around the abdominal area and fat losses in the rest of their body (periphery face, arms and legs), indicative of lipodystrophy. As a result, some PLWH may struggle simultaneously with central fat accumulation and peripheral losses, trying to balance these 2 opposite effects. MethodsPB is a 62-year-old, African-American male infected with HIV for 12 years, receiving an NRTI regimen. Participating in the Miami Adult Studies in HIV (MASH) Cohort, PB started a 6-month nutrition intervention targeted to lower diabetes risk in prediabetic PLWH. Baseline body mass index (BMI) was 24.1 kg/m2 and waist circumference (WC) was 36.5 inches. Despite having the initial intention to lose weight, PB gained ∼12.4 lbs just a month after initiation. When questioned about the weight gain, PB revealed that he had started taking an appetite stimulant (Megace) to address the wasting on his periphery, claiming that he looked “sickly”. PB stopped taking Megace after he gained >20 lbs (12.3% Wt∆) in 4 months. BMI at this time was 26.3 kg/m2 and WC was 45.5 inches, reflecting a substantially increased risk for metabolic complications. With WC increasing 9 inches and hip circumference increasing only 2 inches, it is evident that a considerable amount of the weight accumulation occurred around the waist. As can be seen, he among others in his situation, are struggling with conflicting goals by simultaneously trying to reduce central obesity and prevent peripheral losses and wasting, something that may be unique to PLWH. ResultsDespite the participant’s difficulties in weight management, his fasting blood glucose (FBG) improved after the 6-month nutrition intervention, with a –14 mg/dL improvement, lowering associated risk for diabetes and cardiometabolic complications. ConclusionsThis improvement in FBG levels suggests that despite the difficulty of effective weight management in these patients, proper glucose values may still be achieved with nutrition counseling and education, thus lowering risk for diabetes and associated complications. Funding SourcesNIGMS-RISE funding, National Institute on Drug Abuse 5U01DA040381-03 and FIU-Dissertation Funding.

Body mass index and weight status misperception among a sample of college students in Yogyakarta, Indonesia

Background: Weight status perception associates with objective weight status and is important in the management of weight control. To date, perception of weight status among Indonesian youths has not been reported.Objectives: This study aimed to examine the association between body mass index and weight status perception in a sample of college students in Yogyakarta Province.Materials and Methods: A sample of 209 boys and 269 girls of college students in Yogyakarta Province were measured for their stature and body weight. Body mass index was calculated (BMI). Data of demographic, exercise, and diet were collected. Weight status perception was based on participant responses to a question regarding how they classified their own body size as underweight, normal, overweight, or obese. Ordinal regression analysis was performed to evaluate factors associated with weight status misperception among boys and girls.Results: Overall, 43.5% of boys and 37.5% of girls misclassified their own weight status by actual BMI. Of particular note, 75.9% of obese boys and 78.6% of obese girls underestimated their weight status as overweight or normal weight. Whereas, 9.1% and 23.4% of normal weight boys and girls respectively, overestimated their weight status. Ordinal regression analysis revealed that, weight status misperception from others was significantly contributed (p&lt;0.01) to misperception of weight status among boys and girls with OR of 10.31 and 8.13 respectively. Diet practicing was significantly correlated with weight status misperception in boys (p&lt;0.05) with an OR of 19.57.Conclusions: Weight status misperception was prevalent among normal weight and obese students. Obese students of both gender and normal weight boys tended to underestimate their weight status, whereas normal weight girls were likely to overestimate their weight status.Bangladesh Journal of Medical Science Vol.16(2) 2017 p.225-232

Effect of Weight Control Counseling in Overweight and Obese Young Adults

This study was carried out to compare groups with individual counseling to examine essential outcomes in young adults in a community pharmacy. A randomized controlled trial was conducted from June 2011 to February 2012. A total of 112 overweight and obese participants were randomly assigned to receive group counseling (n=52) or individual counseling (n=56). Clinical outcomes included weight, waist circumference and body mass index. Eating behaviors were evaluated by a theory of planned behavior questionnaire. Both groups showed significant clinical outcomes. The theory of planned behavior average sum score significantly increased from baseline in the health dieting behavior and subjective norm in group counseling. In the individual group (P<0.05), the score increased significantly from baseline only for health dieting behavior (P<0.05). The logistic regression analysis, factors associated with eating behaviors were: group counseling (OR=4.03, 95% CI: 1.71-9.51), female (healthy dieting behavior: OR=0.37, 95% CI: normative beliefs: 0.15-0.93) and person who attempted to control weight (OR=0.17, 95% CI: 0.03-0.91). Group counseling was not inferior to individual counseling and the group counseling should be used as first line mode for weight control management in young adults.

The Effects of Different High-Protein Low-Carbohydrates Proprietary Foods on Blood Sugar in Healthy Subjects.

The reformulation of ultraprocessed ready-to-consume foods in a low-CHO, high-protein version can produce a significantly lower glycemic response whilst maintaining the valued ready-to-use format and high palatability demanded by consumers. The low impact on postprandial glycemia and the nutritional characteristics of these proprietary foods makes them useful in both weight control management strategies and in the care management of diabetes.

Raphanus sativus cv. Sango Sprout Juice Decreases Diet-Induced Obesity in Sprague Dawley Rats and Ameliorates Related Disorders.

BackgroundObesity is recognized as a leading global health problem, correlated with an increased risk for several chronic diseases. One strategy for weight control management includes the use of vegetables rich in bioactive compounds to counteract weight gain, improve the antioxidant status and stimulate lipid catabolism.Aim of the StudyThe aim of this study was to investigate the role of Raphanus sativus Sango sprout juice (SSJ), a Brassica extraordinarily rich in anthocyanins (AC) and isothiocyanates (ITCs), in a non-genetic model of obesity (high fat diet-HFD induced).MethodsControl groups were fed with HFD or regular diet (RD). After a 10-week period, animals were assigned to experimental units and treated by gavage for 28 days as follows: HFD and RD control groups (rats fed HFD or RD and treated with vehicle only) and HFD-treated groups (rats fed HFD and treated with 15, 75 or 150 mg/kg b.w. of SSJ). Body weight and food consumption were recorded and serum lipid profile was measured (total cholesterol, triglycerides, and non-esterified fatty acids). Hepatic phase-I, phase-II as well as antioxidant enzymatic activities were assessed.ResultsSSJ lowered total cholesterol level, food intake and liver weight compared with HFD rodents. SSJ at medium dose proved effective in reducing body-weight (~19 g reduction). SSJ was effective in up-regulating the antioxidant enzymes catalase, NAD(P)H:quinone reductase, oxidised glutathione reductase and superoxide dismutase, which reached or exceeded RD levels, as well as the phase II metabolic enzyme UDP-glucuronosyl transferase (up to about 43%). HFD up-regulated almost every cytochrome P450 isoform tested, and a mild down-regulation to baseline was observed after SSJ intervention.ConclusionThis work reveals, for the first time, the antioxidant, hypolipidemic and antiobesity potential of SSJ, suggesting its use as an efficient new functional food/nutraceutical product.

The Effect of Regular Breakfast on Body Mass Index in 9- to 10-year-old Czech Children

Background: Eating habits play a crucial role in weight control management; however, little research has examined whether frequency of breakfast consumption influences body mass index (BMI) in middle childhood. Purpose: The purpose of this study was to (a) determine the relationship between BMI and the frequency of breakfast consumption, (b) examine gender differences in the frequency of eating breakfast and starting time of breakfast after waking up, and (c) explore breakfast composition. Methods: The research group consisted of 298 children aged 9–10 years (164 boys and 134 girls). Frequency of breakfast consumption, starting time of breakfast after waking up, and breakfast composition were determined by questionnaire. Results: A statistically significant difference in the regularity of breakfast consumption was found between children of the underweight, healthy weight, and overweight/obese groups (P < .001). There was no statistical gender effect for the frequency and timing of the breakfast (P>.05). Discussion: Our data indicate that regular consumption of breakfast is related to BMI values in children aged 9–10 years independent of gender. Translation to Health Education Practice: Our finding confirmed the importance of breakfast consumption and a healthy eating pattern in middle childhood.

Food Ingredients as Anti-Obesity Agents: A Review

Overweight and obesity have a major impact on global health; their prevalence has rapidly increased in all industrialized countries in the past few decades and diabetes and hypertension are their direct consequences. Pharmacotherapy provides reinforcement for obesity treatment, but should be an adjunctive support to diet, exercise, and lifestyle modification. At present, only orlistat and sibutramine have been approved by the US Food and Drug Administration for long-term use, but sibutramine was withdrawn for sale by the European Medicines Agency. The development of functional foods for the prevention and/or treatment of obesity suppose an opportunity for the food market and involve the knowledge of the mechanisms of appetite and energy expenditure as well as the metabolic sensation of satiety. Strategies for weight control management affect gut hormones as potential targets for the appetite metabolic regulation, stimulation of energy expenditure (thermogenesis), and modifications in the metabolic activity of the gut microbiota. Functional foods for obesity may also include bioactive fatty acids, phenolic compounds, soybean, plant sterols, dietary calcium, and dietary fiber. This review intends to offer an overview of the present situation of the anti-obesity agents currently used in dietary therapy as well as some functional food ingredients with potentially anti-obesity effects.

Water-in-oil microemulsions for effective transdermal delivery of proteins

Introduction: A water-in-oil microemulsion is a thermodynamically stable emulsion that has the capacity to ‘hide’ water-soluble molecules within a continuous oil phase. The very small size of the water droplets within the microemulsion means that these types of formulation can be applied topically to the skin, with the result that peptides and proteins can be delivered effectively into the dermal layer.Areas covered: This review discusses the general problems of peptide and protein delivery following topical application, and compares the possible routes of peptide and protein clearance and distribution within the body following topical administration. Several examples of successful peptide and protein delivery using microemulsions are discussed, in addition to the possible alterations in biological profiles following administration via this route.Expert opinion: Water-in-oil microemulsions present themselves as an effective means of topical delivery of peptides and proteins of all sizes, and in high doses. These formulations are a cheap, stable, pain-free means of delivery of peptides and proteins to the skin. An exciting area of potential development is the area of weight control management. The results using insulin, IGF-I and GHRP-6 given topically are particularly intriguing. Whether these results can be replicated in humans and whether the use of these drugs for potential treatment of obesity will be commercially viable will be particularly interesting.

Investigating the Relationship of Weight Gain and Obesity With Minimal Cognitive Impairment Among Middle-Aged People

This study was carried out with the aim of investigation on a relationship of obesity as a risk factor for MCI so that in case of proving such relationship weight control management could be influential in reducing the number of elderly people stricken to Demans. The present research is of the scientific-comparative type and was performed on 150 middle-aged people from Tabriz. Data was obtained via BM index and MMSE test. In order to analyze the obtained data, t-student test and single-way variance analysis were employed. This study showed that among female middle-aged people including three weight groups, there was a meaningful difference. Obese men and women as compared to two groups “overweight” and “normal weight” and women having overweight compared to women having normal weight are more subjected to the minimal cognitive impairment. Among middleaged men, there was no significant difference between the group having overweight and the obese group.

Secondary prevention through cardiac rehabilitation: physical activity counselling and exercise training: Key components of the position paper from the Cardiac Rehabilitation Section of the European Association of Cardiovascular Prevention and Rehabilitation

Cardiac patients after an acute event and/or with chronic heart disease deserve special attention to restore their quality of life and to maintain or improve functional capacity. They require counselling to avoid recurrence through a combination of adherence to a medication plan and adoption of a healthy lifestyle. These secondary prevention targets are included in the overall goal of cardiac rehabilitation (CR). Cardiac rehabilitation can be viewed as the clinical application of preventive care by means of a professional multi-disciplinary integrated approach for comprehensive risk reduction and global long-term care of cardiac patients. The CR approach is delivered in tandem with a flexible follow-up strategy and easy access to a specialized team. To promote implementation of cardiac prevention and rehabilitation, the CR Section of the EACPR (European Association of Cardiovascular Prevention and Rehabilitation) has recently completed a Position Paper, entitled 'Secondary prevention through cardiac rehabilitation: A condition-oriented approach'. Components of multidisciplinary CR for seven clinical presentations have been addressed. Components include patient assessment, physical activity counselling, exercise training, diet/nutritional counselling, weight control management, lipid management, blood pressure monitoring, smoking cessation, and psychosocial management. Cardiac rehabilitation services are by definition multi-factorial and comprehensive, with physical activity counselling and exercise training as central components in all rehabilitation and preventive interventions. Many of the risk factor improvements occurring in CR can be mediated through exercise training programmes. This call-for-action paper presents the key components of a CR programme: physical activity counselling and exercise training. It summarizes current evidence-based best practice for the wide range of patient presentations of interest to the general cardiology community.

Group behavior therapy versus individual behavior therapy for healthy dieting and weight control management in overweight and obese women living in rural community

To compare group behavior therapy with individual behavior therapy for promoting healthy dieting behavior and weight control in overweight and obese women in rural community. This parallel group, open labeled, randomized non-inferiority trial was conducted from March 2005 to April 2006. A total of 132 overweight and obese women with a mean (S.D.) age of 38.4 (7.9) years and body mass index (BMI) of 28.9 (2.9) kg/m(2) were randomly assigned to receive either group behavior therapy (n = 65) or individual behavior therapy (n = 67). Five intervention sessions were provided biweekly during the 3-month period. Assessments were conducted at months 3, 6, and 12. Primary outcome was mean percentage weight loss at month 6. Other outcomes included anthropometric outcomes, dietary intake, healthy dieting behavior, intention, perceived behavioral control, attitude, and subjective norm. Mean percentage weight loss at month 6 of group behavior therapy was comparable to individual behavior therapy (5.9% (95%CI: 4.5-7.3) versus 5.4% (95%CI: 4.0-6.7)); P = 0.027 for non-inferiority at one sided 0.05 level of significance. Other outcomes were remarkably similar between the two study groups. Attitude, subjective norm, and perceived behavioral control improved slightly; whereas, intention, healthy dieting behavior, and dietary intake improved significantly after interventions. High intention and perceived behavioral control was related to greater weight loss. At 1 year, 73% of participants either lost or maintained their weight. Anthropometric outcomes and healthy dieting behavior were significantly better than baseline. Group behavior therapy was not inferior to individual behavior therapy, and it should be used as the first line mode of behavior therapy for weight control management in a rural community.

Diet-induced thermogenesis: variations among three isocaloric meal-replacement shakes

Objective We determined whether significant differences exist in diet-induced thermogenesis among three low-calorie (1042 kJ, or 250 kcal), liquid meal-replacement shakes of different macronutrient compositions: 1) 100% protein; 2) 62% protein, 28% carbohydrate, and 10% fat (high protein/low carbohydrate); and 3) 17% protein, 75% carbohydrate, and 8% fat (low protein/high carbohydrate). Methods Eight subjects (three men and five women) completed a randomized, double-blind, crossover investigation involving three separate resting-and-reclining energy expenditure measurements taken before and after consumption of one of the shakes. Resting-and-reclining metabolic gas-exchange measurements were taken for 30 min; subjects then drank a 20-oz shake, after which 3 h of additional resting-and-reclining gas-exchange measurements were taken. Results A statistically significant difference in diet-induced thermogenesis ( P < 0.02) was found between the low protein/high carbohydrate shake (79 ± 48 kJ) and the high protein/low carbohydrate shake (209 ± 108 kJ). No significant differences in diet-induced thermogenesis were found in comparison with the 100% protein shake (136 ± 81 kJ). No significant differences in the respiratory exchange ratio over 3 h ( P = 0.33) were found. Conclusions Different types of low-calorie meal-replacement shakes do invoke significantly different thermogenic responses over a 3-h period. However, the 130-kJ (31-kcal) difference found in diet-induced thermogenesis represents only a small contribution to daily energy expenditure so that practical applications for weight-control management appear to be minimal.