Management Of Madhumeha Research Articles

Randomised Controlled Trial on the efficacy of Mamajjaka (Enicostemma littorale Linn.) in the Management of Madhumeha (Diabetes Mellitus)

Diabetes Mellitus is in top ten list of diseases causing mortality. In the year 2011, estimated 366 million people were found to be suffering from diabetes mellitus. By year 2030 this morbidity data will rise to approximately 552 million people worldwide. India is having the largest number of diabetics in the world and gets the name ‘Diabetic capital’. This study was carried out with an aim:-‘To Conduct a Randomised Controlled (Upashayatmaka) Trial on the role of Mamajjaka capsule in the management of Madhumeha (DM type-2)’. In this study total 110 patients of Diabetes were selected from NIA hospital and randomly divided into two groups. Group A (Control group) comprise 54 patients were administered with Tab. Metformin and dose was 500mg tablet 1 BD before meals as advised according to allopathic consultant. Group B (Trial group) comprise 56 patients were administered with Cap. Mamajjaka, dose: 500 mg Capsule 2 BD, before 30 min. of meal with lukewarm water. Total duration trial was 100 days. Results obtained in subjective and objective parameters were analysed for the statistical significance by adapting paired T test and unpaired T test. The study revealed that Group-B was found to be more effective in bringing symptomatic relief and Group-A was found to be more effective in improving biochemical markers in the patients of Madhumeha. Cap. Mamajjaka (Enicostemma littorale Linn.) provided better results, suggests that this can be a good complimentary medicine for the patients who are not getting good relief from modern medicine alone.

EVALUATION OF THE EFFICACY OF ‘MADHUMEHARI CHURNA’ WITH ‘TRIPHALADI KWATHA’ IN THE MANAGEMENT OF MADHUMEHA W.S.R. TO DI-ABETES MELLITUS TYPE-2 (NIDDM)

Introduction: Diabetes Mellitus (DM) is commonly known as Madhumeha in Ayurveda. According to report of W.H.O., Diabetes is one of the largest global health emergencies of the 21st century. Incidence of DM is rising more rapidly in India. According to IDF SEA region, there were 69.1million cases of diabetes in India in 2015. So, effective treatment of diabetes is needed. Method: The present research work has been undertaken, to evaluate the efficacy of ‘Madhumehari churna’ with ‘Triphaladi kwatha’ in the management of Madhumeha W.S.R. to D.M. Type-2. The study was conducted on 15 clinically and pathologically diagnosed patients of Madhumeha [DM type 2]. The selection of patients was made from OPD/IPD of Arogyashala, National Institute of Ayurveda and SSBH, Jaipur (Raj.). The selected patients were given 15 registered patients of DM Type-2 (NIDDM) were administered Madhumehari churna and Triphaladi Kwatha for 30 days After evaluating therapy it was observed that the ‘Madhumehari Churna’ with ‘Triphaladi Kwatha’ showed symptomatic relief in the patients of Madhumeha.

A conceptual review of Madhumeha according to Ayurveda and contemporary science

Diabetes Mellitus (Madhumeha) is a group of metabolic diseases associated with hyperglycemia which is due to absolute deficiency of insulin or diminished biological effectiveness of it characterized by polyuria, polyphagia and polydipsia. It is a single most important metabolic disorder that affects almost every organ/system in the body. In Ayurveda, acharyas have mentioned disease according to the strotasas involved and these diseases are classified according to the Dosha predominance. Out of the four types of Vataj prameha, Madhumeha is one of the type. It is a common chronic metabolic disease which is correlated with Diabetes Mellitus. Diabetes Mellitus is prevalent all over the world with an alarming rise in its prevalence day by day. As per Indian Council of Medical Research – India Diabetes (ICMR INDIAB) study published in 2023, the prevalence of diabetes is 10.1 crore. By 2030, 643 million people will have diabetes globally, increasing to 783 million by 2045. The management of Madhumeha is considered as a global problem. Thus the study has been done to get through the depths of all the insights about the pathogenesis of disease according to both modern as well as ayurved literature which would later prove helpful to precisely establish the curability of disease and to acknowledge the limitations of treatment.

To Evaluate the Clinical Efficacy of Darvyadi Churna in the Management of Madhumeha (Denovo Diabetes Mellitus)

Madhumeha, one among the Vataja Pramehas need utmost consideration in the current scenario in view of the rising incidence. Madhumeha is similar to diabetes mellitus. Diabetes Mellitus is a chronic metabolic disease characterized by elevated levels of blood glucose which leads over time to serious damage to the heart, blood vessels, eyes, kidneys and nerves. The most common is Type 2 Diabetes, usually in adults, which occurs when the body becomes resistant to Insulin or doesn't make enough Insulin. In the past 3 decades the prevalence of Type 2 Diabetes has raised dramatically in countries of all income levels. According to Ayurveda, Madhumeha is manageable with the prescribed Chikitsa in the Samhitas. It is judiciously managed with the help of Yuktikruta Ahara, Vihara and Aushadha (Darvyadi churna). In this case Nidana parivarjana has been followed and this case is being considered as Sthoola Pramehi.

A Comparative Clinicopathological Study on Powder of Aegle marmelos Leaf and Withania coagulans Flower in the Management of Madhumeha

Background: In view of Ayurveda, abnormal and profuse excretion of urine in general is called as Prameha. If we do not treat the Prameha, it leads to Madhumeha. There are many herbs mentioned in Ayurveda that have Madhumehahara property. Hence, to control Madhumeha two effective Ayurvedic drugs, namely, “Aegle marmelos” and “Withania coagulans” were selected for the present study. The study aimed to study the efficacy of A. marmelos leaf and W. coagulans flower powder in the management of Madhumeha. Materials and Methods: For the present study, 40 patients of Madhumeha were randomly selected according to the Inclusion criteria. The prepared medicine was trailed in two groups (Groups A and B) each having 20 Patients. The assessment was in every 10 days of intervals. Discussion and Conclusion: Statistically, A. marmelos leaf powder provided no significant results and W. coagulans flower powder provided significant results in improving subjective and objective signs and symptoms of Madhumeha.

Management of Madhumeha (Diabetes mellitus type 2) through Basti: A case study

Management of Madhumeha (Diabetes mellitus type 2) through Basti: A case study

Comparative safety and study of Shadguna Makaradhwaja prepared from thin foils of gold and residue with Guduchi Ghana (aqueous extract of Tinospora cordifolia Miers.) in management of Madhumeha (type 2 diabetes): A double-blind, randomized, clinical trial

Abstract Background: Diabetes turns out to be an intense worldwide public health problem. Makaradhwaja is in practice for the treatment of Madhumeha (diabetes mellitus) due to its Pramehaghna (antidiabetic) and Rasayana (immunomodulatory and rejuvenating) properties with the number of preclinical and clinical trials in diabetes. The present study was carried out to compare the efficacy of Shadguna Makaradhwaja prepared from (Varkha) thin foils of gold (SM-V) and Shadguna Makaradhwaja prepared from Apakwa Talastha Swarna Bhasma (residue of gold remained at the bottom of glass bottle during Kupipakwa) (SM-R) with Guduchi Ghana (GG) (aqueous extract of Tinospora cordifolia Miers) in type 2 diabetes. Materials and methods: In this prospective, randomized, double-blind clinical trial, 82 patients of type 2 diabetes were treated with SM-V with GG (250 mg) and SM-R with GG (250 mg) twice daily before food with honey for 28 days. The assessment of changes observed in hemogram, blood glucose, lipid profile, hepatic, renal profile, and clinical symptoms was carried out. Results: After 28 days of medication, fasting blood glucose level decreased significantly in SM-R, whereas postprandial blood glucose level significantly decreased in SM-V treated group. A significant improvement in subjective parameters and reduction in blood and urine sugar was noted with baseline. Hemogram and hepatic and renal function profiles (safety parameters) in both groups were not significantly different from the baseline. No adverse events were reported during the study period. Conclusion: SM-V, along with GG, is more effective in comparison with SM-R, thereby improving the quality of life of patients along with significant glycemic control and free from any untoward effect. Makaradhwaja can be used as an effective drug for diabetes.

A Comparative Clinical Study to Determine the Efficacy of Bhudhatrayadi Yoga and Metformin in the Management of Madhumeha w.s.r. to Type II Diabetes Mellitus

Prameha is a chronic disease that is described in all the classics of Ayurveda. Madhumeha is categorised as a subtype of Vataja Prameha. Vata Dosha is mainly vitiated in Madhumeha. The patient passes large quantity of urine which is Kashaya (astringent), Madhura (sweet), Pandu (pale) and Ruksha (dry). Madhumeha is the final stage of all the Prameha when left untreated for long time becomes difficult to treat. In modern medicine signs and symptoms of Madhumeha resembles Type II Diabetes Mellitus. Diabetes is a metabolic disease and is characterised by increase in blood glucose levels, deficiency of insulin or resistance to insulin uptake. 40 patients were selected from the IPD and OPD of Kayachikitsa Department of R.G.G.P.G. Ayurvedic College and Hospital, Paprola, Himachal Pradesh. 20 patients were managed with Bhudhatrayadi Yoga and 20 patients were managed with Tablet Metformin. Bhudhatrayadi Yoga showed moderate improvement in subjective parameters of Madhumeha in the study.

Efficacy and safety of Naga Bhasma and Nisha-Amalaki Churna in the management of Madhumeha (type 2 diabetes) - A double-blind, randomized, controlled clinical trial

Abstract Background: Increasing global incidence of diabetes is a serious issue and large number of researches are undergoing to find promising cure of this chronic disease. Many Ayurveda drugs have been evaluated for anti-diabetic properties; however, researches on metallic/mineral based drugs are very few. The present study aimed to assess the comparative efficacy and safety of Shashti Puta Naga Bhasma (SNB) - Trimshati Puta Naga Bhasma (TNB) with Nisha-Amalaki Churna (NAC), NAC and metformin in the management of type 2 diabetes. Materials and methods: In this prospective, randomized, double blind, active controlled study; 132 patients with type 2 diabetes were included and randomly divided into four groups. Patients were treated with NAC (125 mg) with placebo (roasted Sooji; course powder of wheat flour), SNB (62.5 mg) with NAC (125 mg), TNB (62.5 mg) with NAC (125 mg) twice daily before food with honey while patients in last group were continued with their ongoing Tablet Metformin 500 mg prescribed by physician as standard control without any other additional intervention for 90 days. The assessment of changes observed in blood glucose, glycosylated hemoglobin, lipid profile, hemogram, hepatic, renal profile, and clinical symptoms was carried out. Results: After 90 days of medication, fasting and postprandial blood glucose levels and clinical symptoms in three groups were significantly decreased when compared with baseline except NAC group. Hemogram and hepatic and renal profiles (safety parameters) in the four groups were not significantly different from the baseline. No adverse events were reported with the use of the studied medicine. Conclusion: SNB along with NAC possessed more symptomatic relief in comparison to TNB with NAC, NAC alone and Metformin thereby improving the quality of life of patients along with significant glycemic control and free from any significant side effects.

A CASE STUDY ON MADHUMEHA W.S.R TO TYPE 2 DIABETES MELLITUS TREATED WITH CHANDRA KALA GUDIKA

The rising burden of Type 2 Diabetes which has occurred with modernization can be understood in the context of epidemiological transition. Irregular food habits, lack off exercise, stress and strains are some causative factors. Madhumeha leads to be a cause for blindness, renal failure etc., if it is not controlled. Rapid socio economic development and coca colonization have resulted in a life style transition from traditional to modern. As Madhumeha in modern science is compared with diabetes mellitus. Aims of Study-The present study was carried out with an objective to compare the efficacy of Chandra kala gudika in the management of Madhumeha w.s.r. to type 2 Diabetes Mellitus. Materials and Methods- The present study was Open Randomised clinical study, on 30 patients of either sex having symptoms of Madhumeha. These patients were subjective with Chandra kala gudika 500mg Bd. Result- Overall response was excellent improvement in 30%, marked improvement in 60% and mild improvement in 10% of patients. Conclusion- The Chandra kala gudika has a significant effect on both subjective and objective parameters. No adverse drugs effects were observed at the end of study.

A Case Study to Evaluate the Role of Trayaushnadi Vati in the Management of Madhumeha (Type 2 Diabetes Mellitus)

India is known as the diabetes capital of the world. By 2025, the country's diabetes population will have risen to 69.9 million, and by 2030, it will have risen to 80 million. This means that the developing country is anticipated to have a 266% gain. In the present study, a 35-years-old obese male patient came to the OPD with complaints of Daurbalyata (weakness), Atimutrata (increased frequency of micturition) and Atitrishna (excessive thirst) since seven days. The diagnosis leads to Madhumeha (Type 2 Diabetes mellitus) through physical findings and biochemical investigations. The treatment plan opted for was Trayaushnadi Vati with a change in diet and lifestyle. This case study emphasizes the usefulness of Ayurveda and it aims to detoxify, purify, strengthen and balance the body Dosha (regulatory functional factors of the body) of the body Dhatus (major structural components of the body) to attack the root cause and ensure complete healing. Several medicinal herbs appear to be as beneficial as traditional anti-diabetic medications in lowering HbA1c levels. To determine the benefits of prospective plant-based medicines on diabetes, rigorous trials with at least 3 months of follow-up are required.

Effect of Triphaladi Kwatha in Madhumeha (Diabetes Mellitus Type 2) - A Case Report

Diabetes is a chronic metabolic disorder characterised by abnormally highly increased blood glucose levels. About 537 million adults (20-79 years) are living with diabetes and it is predicted to rise in number to 643 million by 2030 and 783 million by 2045. Despite many treatment options, the havoc of diabetes is increasing day by day, and along with this, it is becoming the causative factor for other diseases too. In Ayurveda, diabetes mellitus type 2 is similar to Madhumeha. Many herbal formulations are mentioned in the Ayurvedic literature for the treatment of Madhumeha in which Triphaladi kwatha is one of them. The present case is about a 39-year-old male patient who presented with weight loss, increase urine frequency, excessive thirst, pain in calf muscle and mild cramps in leg. The laboratory investigations showed increased fasting blood sugar level, post-prandial blood sugar level, and HbA1c. The patient was treated with Triphaladi kwatha (Ghanvati) and was advised proper diet and physical activity. After completion of therapy, a significant improvement was found in weight and other subjective symptoms. Fasting blood sugar level was reduced to 92 mg/dl from 102.9 mg/dl, Post-prandial blood sugar level decreased to 123 mg/dl from 210 mg/dl and HbA1c decreased to 5% from 5.9%. The observation indicated that Ayurvedic formulation along with proper diet and physical activity is helpful in the management of Madhumeha(diabetes mellitus type 2).

An open label, single arm prospective clinical study on the effectiveness of Pugaarimeda Kashaya in Madhumeha (Diabetes Mellitus Type 2)

Background: Diabetes mellitus (DM) is one of the most common non-communicable diseases globally. It is characterized by multiple metabolic disorders that results in hyperglycemia. Diabetes mellitus type-2 (DM2) is the most common type accounting almost 90% of cases of DM. Madhumeha on the basis of similar etiology, signs and symptoms can be co-related with Diabetes mellitus type-2. It is also described by the term Kshoudrameha or Ojomeha. Pugaarimeda Kashaya with Madhu as Anupana is mentioned in Brihat Nighantu Ratnakara in the management of Madhumeha. Objective: To clinically evaluate the effectiveness of Pugaarimeda Kashaya in Madhumeha (Diabetes mellitus type-2). Materials and Methods: Among 31 registered subjects, 28 of them completed the course of treatment. They were administered with Pugaarimeda Kashaya orally 100ml per day (50ml twice daily before food) with Anupana of Madhu 5ml for a period of 30 days. Blood and urine glucose test was done on 1st, 31st day of study initiation. For Statistical analysis subjective parameters were assessed by Cochran’s Q test followed by McNemar test and objective parameters were assessed by Paired sample T Test. Results: There was statistically significant improvement observed in the signs and symptoms of Madhumeha with blood and urine glucose levels. (p<0.05) Conclusion: Pugaarimeda Kashaya was found effective in the management of Madhumeha.

Bhudhatryadi Yoga in Madhumeha (diabetes mellitus type 2) : An open label single arm clinical study

Background: Diabetes mellitus is a metabolic disorder characterized by persistent hyperglycemia either due to less production of insulin or resistance of insulin receptors. Globally 463 million individuals are affected by type 2 diabetes & 77 million belong to India. India is deemed as the world's capital of diabetes. It can be correlated to Madhumeha. Bhudhatryadi Yoga is mentioned for the treatment of Prameha. Bhudhatryadi Yoga has Tikta Rasa, Laghu-Ruksha Guna, Sheeta Veerya. Katu Rasa of Maricha is Deepana and Pachana. It does Kleda Shoshana, Meda Shoshana and Kapha Harana. It removes Sroto Rodha and thereby helps in alleviating Kapha Prakopa. The effect of methanol extract of aerial parts of Bhumyamlaki has α–amylase & α–glucosidase enzyme inhibitory properties. α –amylase & α – glucosidase aid the production of glucose from the catabolism of starches and oligosaccharides. Methods: 28 registered subjects, 23 completed the course of intervention. They were administered with Bhudhatryadi Yoga orally 12 gm per day (6 gm twice daily before food) with Anupana of lukewarm water for a period of 30 days. Blood and urine glucose test was done on 1ST, 7TH and 30th from the day one of study initiation. For Statistical analysis subjective parameters were assessed by Cochran’s Q test followed by McNemar test and objective parameters were assessed by Repeated Measures Anova and Paired T Test. Results: There was statistically significant improvement observed in the signs and Symptoms of Madhumeha with blood and urine glucose levels. (p<0.05). Interpretation and Conclusion: Bhudhatryadi Yoga is effective in management of Madhumeha.

A Case Study on the Management of Type 2 Diabetes Mellitus (Madhumeha) by Ayurvedic Intervention

Diabetes Mellitus is a metabolic disorder associated with multisystem complications. The prevalence and incidences of the both types of diabetes are significantly increased over the past two decades. The recently published ICMR-INDIAB national study reported that there are 62.4 million people with type 2 diabetes mellitus and 77 million people with prediabetes in India. These numbers are projected to increase to 101 million by the year 2030 due to changed of life style of the people all over the world. Habits of sedentary life, having a lot of fast foods and improper follow of diet habits are the main causes to develop Diabetes mellitus. It can be correlated with Madhumeha in Ayurveda. A 45 years old female patient treated in the OPD of Central Ayurveda Research Institute, Guwahati from 23rd Sept. 2020 with a complain of generalised weakness, weight loss, increase amount of urination and attraction of ant towards the excreted urine for 9 months. Examination, laboratory investigations and history leads to diabetes mellitus. Different Ayurvedic herbomineral drugs which were mentioned in different texts were given to the patient. It shows the effective results in the management of Madhumeha (Diabetes mellitus).

Management of Madhumeha with Vallipanchmool Churna – A Case Study.

Diabetes Mellitus is a major health problem in the whole world. In spite of tremendous advancements of the modern system of medicine as OAD (oral anti-diabetic drug) and insulin therapy, to date, an ideal drug that can control hyperglycemia is still a distant dream. It has been a challenge for Ayurveda to search for additional effective solutions resulting in the better management of the disease. There is a need for effective, safe and potent medicine which can control hyperglycemia related to type II diabetes and has no side effects. In this case study, we used Ayurvedic medicine ‘Vallipanchmoolchurna’ mentioned in Sushruta Samhita in a single case study which was done on the use of Vallipanchmool churna on type II Diabetes Mellitus. A significant reduction was seen in blood sugar level fasting and post-meal.

Role of Argwadha Nitya Virechana in Madhumeha (Diabetes Mellitus-II): A Case Study

Diabetes Mellitus is now considered a pandemic. Especially in India, the number of patients increased at 14% prediabetic, becoming the capital of Diabetes. It is a clinical syndrome which is characterize by an increased level of blood sugar. In Ayurveda, the ṁadhumeha is explained as a type of prameha. The kinds of madhumeha is of two. One is dhatukshaya, and other is avaranjanya. The avaranjanya type of Madhumeha is allowed to be treated with the shodhana process. In which vamana and virechana are effective.
 Objective: The objective of this study was to study the efficacy of Nitya Virechana in the management of madhumeha.
 Case report: A single case study of a 59 yrs old male patient who was already diagnosed with madhumeha before 21 days. Symptoms such as pippasa, shramdaurbalya, Bahumutrata were present; after investigation, he was advised for Nitya Virechana.
 Result: Symptomatic assessment of the patient was carried out after treatment i.e. after Nitya Virechana and outcome was satisfactory, and the quality of life of patient was significantly improved.
 Conclusion: Nitya Virechana brought about good relief in symptoms in patients with Madhumeha and controlling the blood sugar level.

A clinical study to evaluate the role of Madhumehari Vati in the management of Madhumeha type 2 diabetes

Background: Type 2 Diabetes is a major, non-communicable disease with increasing prevalence at the global level. Type 2 diabetes is a metabolic disorder which can be correlated with Madhumeha. Madhumeha is Tridoshaj in origin with predominance of Vata and Kapha. Type 2 diabetes results when the body produces insufficient insulin or the body cannot use the insulin it produces. Most of the contents of Madhumehari Vati are having Katu (pungent), Tikta (bitter), Kashaya (astringent) Rasa (taste), Laghu (light), Ruksha (rough) Guna (properties), Katu (pungent) Vipaka (taste after digestion), Ushna (hot) Virya (potency), Deepana, Pachana Kapha-Pitta Shamaka properties and hypoglycaemic,antidiabetic activity,Hepatoprotective, hypolipidemic and antioxidant activities which are essential in the management of Madhumeha (type 2 diabetes). So, this study was taken up to evaluate the effectiveness of Madhumehari Vati in the management of Madhumeha (type 2 Diabetes). Aim of the study was to evaluate the efficacy of Madhumehari Vati in the management of Madhumeha w.s.r type 2 diabetes.Methods: Total 31 patients were selected from OPD of Kayachikitsa, department, I. T. R. A., Jamnagar. In this study Madhumehari Vati was given in dose of one tablet (1000 mg each) three times in a day with plain water before meal.Results: After the course of therapy for 8 weeks, statistically highly significant improvement was found in subjective parameters like Pindikodwestana (calf muscles cramps), Guru Gatrata (heaviness of body), Supti (numbness), Karapada Daha (burning sensation in palm and soles), Prabhutamutrata (polyuria), Atipipasa (polydipsia) whereas Shithila Angata (flaccidity of body parts), Swedadhikya (excessive sweating), Kshudha Adhikya (polyphasia) and Nidra Adhikya (excessive sleep) remained statistically significant (p<0.05). In objective parameters statistically highly, significant improvement was found in post prandial blood glucose whereas statistically significant improvement was found fasting blood glucose and HbA1C.Conclusions: Madhumehari Vati is effective in the management of Madhumeha (type 2 diabetes). No ADR (adverse drug reaction) was reported during the study.

A clinical study on the effect of Panchatikta Pancha Prashritik Basti in the management of Madhumeha w.s.r to type 2 DM

Madhumeha (Type 2 Diabetes mellitus) is a syndrome with disturbed metabolism and hereditary immune mediated involvement and its becomes worse with evident of life threatening complications like Neuropathy, Nephropathy, Retinopathy along with pathological changes that involves small and large vessels leading to myocardial problems and cerebrovascular accidents. Ayurveda emphasizes on the radical treatment by the use of Panchakarma therapies, which are primarily bio-cleansing in nature and corrects the basic pathological factors involved in the disease and regularize metabolism. The drug used in Panchakarma detoxification process are nontoxic, medicated oils and ghee, together with Panchakarma procedure sequentially loosen and remove lipid soluble toxicants from their deposited sites and stimulate their elimination. In Ayurveda Panchatikta pancha prashritika Basti (PPP Basti) is specially indicated for Madhumeha. In this clinical study PPP Basti has given in diagnosed Diabetic Patient and their result shown statistically significant improvement in the sign and symptoms.

AYURVEDIC MANAGEMENT OF DIABETES MELLITUS - A SINGLE CASE STUDY

Background: The study was intended to have a theoretical audit of the Madhumeha and its treatment spe-cifically to the utilization of a natural drug Phalatrikadi kwatha. Madhumeha, otherwise called Diabetes Mellitus is one of the sorts of Vataja prameha, that has been considered as an incurable illness (Ma-hagada). Because of extravagance in etiological components it brings about the inadequate arrangement of Kapha and Meda which further continues descending through the channels of Mutravaha srotas and get confined at Basti mukha prompting the side effects like Prabhoota mutrata (polyuria), Avila mutrata (tu-bidity of pee) and so on. As the disease is Chirakari, it requires a compelling treatment which can be pro-ceeded for quite a while with no evil impacts. Among the numerous treatment measures referenced, Phala-trikadi kwath has been chosen in this examination and the impact was assessed. Method: In the current logical examination a 53 years old Male directed in Outpatient having Objections of the patient was increased thirst, frequent urination, hunger, fatigue and blurred vision. By taking a gander at the signs and appearances of complaints of patient was resolved to have Diabetes after exhortation glucose tests reports. In the current case report lenient was required to treat with ayurvedic plan under the treatment of Diabetes. Going to the OPD of YMT Ayurvedic Hospital Kharghar and treated with preliminary medica-tion (Phalatrikadi kwatha). Patients were assessed in a time period for 15 days. FBS, PPBS with clinical sign and manifestations were tested. Result: In the wake of assessing the absolute impacts of the treatment, it was seen that Phalatrikadi kwath alongside diet and routine gave good alleviation. Conclusion: Significant result was observed with this treatment protocol in the management of Madhume-ha.