Fatigue Management Research Articles

Visual fatigue prediction using classification model based on physiological responses of occupants under office lightings

Appropriate management of visual fatigue is crucial for eye health as it significantly impacts life quality throughout an individual's life cycle. The shift to digital tasks in modern office environments has increased occupants' exposure to visual fatigue, leading to various social problems. This study aimed to develop visual fatigue prediction models based on physiological responses and classification algorithms. Experiments were conducted to collect physiological responses and subjective visual fatigue under various lighting environments. Collected data was refined and reorganized as predictor variables by different time windows and target variables by scales. Then, visual fatigue prediction models were developed using supervised machine learning algorithms (i.e., artificial neural network, support vector machine, gradient boosting machine, and random forest). And improved by feature selection and adding subject-label variables. The resulting two-scale and three-scale visual fatigue prediction models demonstrated an average performance of 93.73 % and 94.64 % respectively. This research can contribute to reducing societal costs and enhancing productivity by proposing visual fatigue prediction models that help manage eye health in office environments.

Fatigue management effects on social participation and environment management in individuals with multiple sclerosis: Quasi-experimental study

Fatigue management effects on social participation and environment management in individuals with multiple sclerosis: Quasi-experimental study

INTEGRATING ALLIED HEALTH PROFESSIONALS DURING THE ONCOLOGICAL TREATMENT PHASE FOR GLIOBLASTOMA PATIENTS: A CASE STUDY AT A UK CANCER CENTRE

Abstract AIMS Primary brain tumour patients should be offered neurological rehabilitation assessment at diagnosis and every stage of follow With only 5% of glioblastoma patients surviving more than 5 years, specialist management that spans across all phases of the Dietz rehabilitation model is required to optimise function, treatment tolerance and Quality-of-life. At Guy’s cancer centre an Allied health multi-disciplinary team (Physiotherapy, Occupational therapy and Speech and language therapy) work alongside the oncologist-led clinic to support this patient group. METHOD Case history A 54-year-old, male, was diagnosed with right parietal Glioblastoma, WHO grade 4, IDH wildtype, MGMT 5.47% methylated (August 2023) on biopsy only. He underwent chemo/radiotherapy - 60gy/90 fractions with Temozolmide (TMZ) on 3/11/2023 Currently C4 of adjuvant TMZ. Dexamethazone 2mg was discontinued on 29/11/2023, he continues with Keppra 500mg twice daily. RESULTS Dietz Intervention approach in phases: PREVENTATIVE Fatigue management was introduced prior to radiotherapy including a physical activity review, advice on pacing, sleep hygiene and relaxation techniques. Given the patient’s history of shift work and altered sleep patterns, managing risks of treatment-related fatigue was of particular importance. Restorative & Supportive: A targeted and periodised exercise programme was initiated, comprising 1:1 gym based physiotherapy sessions. The aims included enhancing exercise confidence, improve balance, endurance, maintain strength, pain management and weight maintenance during chemo/radiotherapy and adjuvant TMZ. Education was deployed on adjusting activity levels based on chemotherapy cycle and day to day side effects, alongside ongoing fatigue management advice around pacing and sleep hygiene. CONCLUSION Learning and Recommendations Implementing tailored rehabilitation interventions early in the patient’s treatment pathway, enables proactive management to mitigate the impact of treatment-related side effects on their QOL. Based on our experience, early engagement with a dedicated therapy team is recommended to foster strong rapport with both the patient and their caregivers. This facilitates timely rehabilitation planning for optimal outcomes.

Women's Experience and Management of Cancer-Related Fatigue and Psychological Distress During Treatment for Gynaecological Cancer: A Qualitative Study.

To explore women's experience and management of cancer-related fatigue and psychological distress during treatment for gynaecological cancer. Qualitative descriptive study. Face-to-face semistructured individual interviews were conducted with 23 women in mainland China undergoing treatment for gynaecological cancer between July and October 2023. Data were analysed using content analysis. Three categories were identified: overwhelming experience of cancer-related fatigue, diverse experiences of psychological distress and strategies for managing cancer-related fatigue and psychological distress. Participants reported physical exhaustion and emotional fatigue, disrupting their normal lives. Psychological distress included distress due to cancer treatment, psychological burden associated with social relationships, frustration with being ill and worries about disease progression and recurrence. Strategies for managing symptoms were mainly nonpharmacological, with some unable to find suitable methods. This study found that participants had a complex experience of cancer-related fatigue and psychological distress, influenced by social expectations regarding women's roles and treatment impacts on reproductive health and femininity. These findings underscore the need for comprehensive interventions involving family members or fellow patients to reduce both symptoms. Nurses should focus on addressing cancer-related fatigue and psychological distress in women receiving treatment for gynaecological cancer, particularly in adolescents and young adults. It is essential to provide comprehensive care to improve their physical and psychological well-being. This study explored how women with gynaecological cancer experience and manage cancer-related fatigue and psychological distress. The findings highlight the need for holistic care that addresses physical and psychological symptoms. Nurses should consider the impact of reproductive health and femininity on symptom experiences and management. Furthermore, the findings could inform the development of evidence-based interventions to improve the physical and psychological well-being of women with gynaecological cancer. Standards for Reporting Qualitative Research checklist. No patient or public contribution.

Identifying fatigue of climbing workers using physiological data based on the XGBoost algorithm.

High-voltage workers often experience fatigue due to the physically demanding nature of climbing in dynamic and complex environments, which negatively impacts their motor and mental abilities. Effective monitoring is necessary to ensure safety. This study proposed an experimental method to quantify fatigue in climbing operations. We collected subjective fatigue (using the RPE scale) and objective fatigue data, including systolic blood pressure (SBP), diastolic blood pressure (DBP), blood oxygen saturation (SpO2), vital capacity (VC), grip strength (GS), response time (RT), critical fusion frequency (CFF), and heart rate (HR) from 33 high-voltage workers before and after climbing tasks. The XGBoost algorithm was applied to establish a fatigue identification model. The analysis showed that the physiological indicators of SpO2, VC, GS, RT, and CFF can effectively evaluate fatigue in climbing operations. The XGBoost fatigue identification model, based on subjective fatigue and the five physiological indicators, achieved an average accuracy of 89.75%. This study provides a basis for personalized management of fatigue in climbing operations, enabling timely detection of their fatigue states and implementation of corresponding measures to minimize the likelihood of accidents.

Fatigue management while working night shifts in the delivery suite

Fatigue management while working night shifts in the delivery suite

Improved Fatigue Management in Primary Sjögren's Syndrome: A Retrospective Analysis of the Efficacy of Methotrexate in Chinese Patients.

To assess the efficacy of methotrexate (MTX) and hydroxychloroquine (HCQ) in improving fatigue symptoms in patients with primary Sjögren's syndrome (pSS). A single-center retrospective study was conducted on pSS patients experiencing fatigue symptoms. All patients received either MTX, HCQ, or a combination of MTX + HCQ for a period of six months. Clinical efficacy was measured using the European League Against Rheumatism (EULAR) Sjögren's Syndrome Disease Activity Index (ESSDAI), EULAR Sjögren's Syndrome Patient Reported Index (ESSPRI), Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F), fatigue severity scale (FSS), and visual analog scale (VAS) score. These measures were assessed at baseline and at 1, 2, 3, and 6 months. A total of 86 pSS patients with fatigue symptoms were enrolled (27 received MTX, 29 received HCQ, and 30 received MTX + HCQ). Patients receiving MTX and MTX + HCQ showed significant improvements at 6th month in ESSDAI, ESSPRI, FSS, FACIT-F, and VAS scores (all P < 0.01) compared with baseline. Repeated-measures analysis of variance revealed that patients treated with MTX and MTX + HCQ experienced significant improvements in ESSDAI, FSS, FACIT-F, and VAS scores (all P < 0.01) from baseline to the 6th month. The HCQ group did not show significant improvement in FSS, FACIT-F, and VAS scores (all P > 0.05), although their ESSDAI and ESSPRI scores did improve significantly (all P < 0.01). Patients in the MTX group showed the most improvement in mean changes of ESSDAI score, FSS score, FACIT-F score, and VAS score from baseline to the 6th month. And patients received MTX treatment significantly had more fatigue remission numbers (all P < 0.05). In clinical practice, methotrexate is more effective than hydroxychloroquine in improving fatigue symptoms, as measured by patient-reported fatigue scales (FSS, FACIT-F, and VAS scores) in patients with pSS.

The Effects of Home-Based Walking on Cancer-Related Fatigue in Patients with Breast Cancer: A Systematic Review

Objective: Home-based walking programs can be a good option for breast cancer patients with fatigue. However, studies on the effectiveness of home-based walking exercise programs have not fully defined proper exercise prescriptions that may be safe and beneficial for breast cancer patients, and their effects on fatigue are still controversial. This systematic review aimed to evaluate the effect of home-based walking on fatigue management in patients with breast cancer. Method: In this study, electronic databases such as Scopus, Pubmed, Web of Science, Medline, Science Direct, and Ebsco Ultimate were searched. The randomized controlled studies published between January 2002 and February 2022 were included in the study. The data were summarized narratively. Results: Patients in the studies consisted of young individuals. The majority of their cancer stages ranged from I to III. A significant part of them received chemotherapy. Home-based walking was found to have positive effects on cancer-related fatigue in women with breast cancer. Home-based walking prescriptions were provided to patients through face-to-face or telephone counseling or printed learning materials. It was determined that the exercise frequency, duration and intensity of home-based walking programs varied in the studies. Conclusion: Home-based walking was found to have positive effects on cancer-related fatigue in women with breast cancer. Therefore, home-based walking can be a simple, cost-effective and safe approach to women with breast cancer. The heterogeneity in reporting procedures suggests that further high-quality and uniform studies should be conducted to reach a stronger consensus on the effects of home-based walking program on fatigue.

Work-related musculoskeletal disorder and health risk behaviors in market-vendors: a mixed-methods study.

Work-related musculoskeletal disorders (WRMDs) are frequently observed among market vendors, and engaging in health risk behaviors can exacerbate these issues, leading to various health problems. Common health risk behaviors among market vendors include alcohol consumption and insufficient physical activity. However, there is currently a lack of research examining the prevalence of WRMDs and health risk behaviors among market vendors in Bangkok. Furthermore, the emerging trend of drug misuse within this group remains poorly understood. This study aims to explore the prevalence of muscle pain and flexibility issues and assess health risk behaviors, including alcohol consumption, inadequate exercise, and drug misuse, among market vendors. A mixed-method study was undertaken among 213 market vendors in Bangkok. Data collection utilized direct observation techniques, questionnaires, and muscle flexibility tests. Qualitative data were elucidated and showcased through textual descriptions and quotations. Quantitative data were analyzed using descriptive statistics to present numerical and percentage values. Qualitative findings revealed that market vendors often engage in static muscular work and maintain awkward postures due to their job characteristics and workstation setups. Quantitatively, the right arm was the most common pain region (34.7%), followed by the left leg (31.0%), right leg (30.0%), and left arm (28.6%). Additionally, 64.3% of participants showed poor muscle flexibility. The study also found that 35% of market vendors resorted to alcohol and 11.7% to drug misuse to cope with fatigue and prevent adverse symptoms. Moreover, 68.5% of participants reported no regular exercise due to lack of time. The study highlights the prevalence of musculoskeletal issues among market vendors, largely attributed to static muscular work and awkward postures dictated by their job roles and workstation arrangements. The right arm emerged as the most commonly affected area, followed by the left leg, right leg, and left arm, with significant rates of reported pain. The research also points to a notable lack of muscle flexibility in a majority of vendors and a concerning tendency towards alcohol and drug misuse as coping mechanisms for fatigue and symptom management. Furthermore, a significant portion of the vendors do not participate in regular exercise, primarily due to time constraints. These findings can be used to implement health prevention programs within the market vendor group.

Improvement of fatigue management methodology related to flight crew

This research focuses on flight crew fatigue and the improvement of a fatigue management methodology that helps in reducing fatigue for flight crew members, aiming to improve their well-being and overall aviation safety of flights. A thorough literature review established a foundation for understating fatigue and the available methodologies for fatigue management for flight crew members. To make the picture clearer, an empirical study was conducted, and it included surveys and interviews with flight crew members. The gathered data underwent detailed statistical and thematic analysis to identify key factors influencing fatigue among flight crew members. Findings revealed multiple contributors to the flight crew member fatigue. Using these insights, a fatigue management methodology is proposed, integrating real-world experiences with evidence-based strategies. The proposed methodology and the recommendations that were formed are relevant for a company management which is facing flight crew fatigue management issues.

Exploring the usefulness of real-time digitally supported fatigue monitoring in fatigue management: Perspectives from occupational therapists and brain injury survivors

Introduction: Persistent fatigue after acquired brain injury (ABI) needs long-term self-management. Self-monitoring supports self-management and informs the use of fatigue management strategies. Using ecological momentary assessment to monitor fatigue offers a data-driven approach to managing fatigue. Aims: To explore the usefulness of self-monitoring fatigue in real-time, using ecological momentary assessment to support self-management, from the perspective of people with ABI and occupational therapists. Methods: People with ABI monitoried their fatigue by wearing a Fitbit and completing six surveys a day on their phone for 6 days. Think aloud and semi-structured interviews elicited views on self-monitoring and the data generated. Transcripts were analysed using reflexive thematic analysis. Results: Four themes were developed from people with ABI ( n = 9): (1) Attending to experience, (2) making sense of data, (3) the relationship between fatigue and activity, (4) implications for daily life. Three themes from occupational therapists ( n = 5): (1) Challenges of using of data, (2) perceived benefits of self-monitoring, (3) viewing data in relation to their understanding of fatigue. Conclusion: Data generated in real-time challenged perspectives on fatigue and fatigue management. These insights may help people with ABI and their clinicians to plan personalised strategies for fatigue management and evaluate its impact on daily living.

Analysis of Wavelet Coherence in Calf Agonist-Antagonist Muscles during Dynamic Fatigue.

Dynamic muscle fatigue during repetitive movements can lead to changes in communication between the central nervous system and peripheral muscles. This study investigated these changes by examining electromyogram (EMG) characteristics from agonist and antagonist muscles during a fatiguing task. Twenty-two healthy male university students (age: 22.92 ± 2.19 years) performed heel raises until fatigue. EMG signals from lateral gastrocnemius (GL) and tibialis anterior (TA) muscles were processed using synchrosqueezed wavelet transform (SST). Root mean square (RMS), mean frequency (MF), power across frequency ranges, wavelet coherence, and co-activation ratio were computed. During the initial 80% of the task, RMS and EMG power increased for both muscles, while MF declined. In the final 20%, GL parameters stabilized, but TA showed significant decreases. Beta and gamma intermuscular coherence increased upon reaching 60% of the task. Alpha coherence and co-activation ratio remained constant. Results suggest that the central nervous system adopts a differentiated control strategy for agonist and antagonist muscles during fatigue progression. Initially, a coordinated "common drive" mechanism enhances both muscle groups' activity. Later, despite continued increases in muscle activity, neural-muscular coupling remains stable. This asynchronous, differentiated control mechanism enhances our understanding of neuromuscular adaptations during fatigue, potentially contributing to the development of more targeted fatigue assessment and management strategies.

Medical and neurologic management of brain tumor patients.

This article discusses commonly encountered medical and neurological complications in patients with brain tumors and highlights recommendations for their management based on updated evidence. Use of dexamethasone is correlated with worse prognosis in patients with glioblastoma, and in brain metastases, high doses may lead to increased side effects without additional clinical benefit. There are multiple antiseizure medications (ASM) to choose from and possible interactions and toxicity must be considered when choosing an agent. Additionally, there is growing interest in the use of AMPA receptor blockers as ASM in patients with brain tumors. Nonpharmacological strategies for the management of fatigue remain paramount. Cognitive decline is common after whole brain radiation (WBRT) and hippocampal-sparing WBRT results in superior cognitive outcomes. Venous thromboembolism is a common complication and there is growing evidence on the use of direct oral anticoagulants (DOACs) in this population. There is evolving evidence on the management of medical and neurological complications in patients with brain tumors. These complications, require early identification and multidisciplinary collaboration and expertise.

Education for fatigue management in people with multiple sclerosis: Systematic review and meta-analysis.

Fatigue is a common and disabling symptom in multiple sclerosis (MS). Educational interventions have shown potential to reduce fatigue. The aim was to systematically review the current best evidence on patient education programmes for MS-related fatigue. This was a systematic review and meta-analysis following Cochrane methodology. A systematic search was conducted in eight databases (September 2023). Moreover, reference lists and trial registers were searched and experts in the field were contacted. Randomized controlled trials were included evaluating patient education programmes for people with MS with the primary aim of reducing fatigue. In total, 1176 studies were identified and assessed by two independent reviewers; 15 studies (1473 participants) were included. All interventions provided information and education about different aspects of MS-related fatigue with different forms of application, some with components of psychological interventions. Amongst those, the most frequently applied were cognitive behavioural therapy (n = 5) and energy-conservation-based approaches (n = 4). Studies differed considerably concerning mode of intervention delivery, number of participants and length of follow-up. Interventions reduced fatigue severity (eight studies, n = 878, standardized mean difference -0.28; 95% confidence interval -0.53 to -0.03; low certainty) and fatigue impact (nine studies, n = 824, standardized mean difference -0.21; 95% confidence interval -0.42 to 0.00; moderate certainty) directly after the intervention. Mixed results were found for long-term effects on fatigue, for secondary endpoints (depressive symptoms, quality of life, coping) and for subgroup analyses. Educational interventions for people with MS-related fatigue may be effective in reducing fatigue in the short term. More research is needed on long-term effects and the importance of specific intervention components, delivery and context.

Evaluating cancer rehabilitation services: Insight from Australia and New Zealand

Background: Despite evidence supporting the benefits of rehabilitation for cancer survivors, the nature of cancer rehabilitation programs is inadequately described in Australia and New Zealand. This study provides insight into current service delivery and challenges for healthcare systems in implementation of cancer rehabilitation programs. Methods: A cross-sectional survey of directors of public and private rehabilitation services in hospital and ambulatory settings across Australia and New Zealand using the Australasian Rehabilitation Outcomes Centre (AROC) registry evaluated the current delivery of cancer rehabilitation programs, health professional workforce, core care components delivered, barriers and facilitators to service delivery, and unit/organisation-wide cancer rehabilitation activities. Descriptive statistics analyzed quantitative data, and qualitative analyses interpreted item responses. Results: Of the 300 services, 102 (34%) participants completed the survey. Most services provide non-dedicated cancer rehabilitation programs (n=63), led by rehabilitation physicians, followed by allied health. The common tumour streams referred included central nervous system (67%, n=56), haematological (59%, n=49), prostate (58%, n=48), and lung cancers (58%, n=48). Patients were frequently referred during post-treatment (87%, n=72) and treatment phases (66%, n=55). Core program components were multimodal exercises, fatigue management strategies, and management of medical complications and medications. The main barriers and facilitators toward the uptake of cancer rehabilitation programs were identified. Key activities in education, research, advocacy, and clinical practice improvement were also highlighted. Conclusions: The survey identified key barriers and facilitators for the implementation of cancer rehabilitation programs. Collaborative efforts of relevant stakeholders, clinicians, consumers, and policymakers need to address barriers to broader implementation of cancer rehabilitation services.

Enhancing pilot vigilance assessment: The role of flight data and continuous performance test in detecting random attention loss in short IFR flights

Situational awareness (SA) and fatigue management are crucial aspects of aviation safety, particularly during demanding flight phases. This study introduces an innovative approach employing flight data, machine learning, and Continuous Performance Test (CPT) metrics to predict pilot performance and SA during instrument approaches under Instrument Meteorological Conditions (IMC). Data were collected from over 10 pilots across more than 40 flights in a high-fidelity Cessna 172 analog flight simulator.Significant correlations were observed between dynamic cognitive performance parameters and the exceedance shape factor, a novel measure of pilot sustained attention introduced in this research. Key variables identified through correlation analysis included variability, interstimulus change, and reaction time standard deviation.Importantly, commission scores and reaction time standard deviation emerged as key predictors in the machine learning model, specifically the Optimizable Gaussian Process Regression (GPR) model with a radial basis function kernel. The model achieved a validation R-squared of 0.90 and a test R-squared of 0.70. These systems could incorporate additional data sources, such as eye-tracking and scan pattern analysis, for a better assessment of pilot SA and fatigue levels. While post-flight measurements are inherently reactive, they are effective for monitoring the degradation of pilot CPT scores after each leg of high-frequency, short-duration flights.Notable limitations include the need to understand individual cognitive differences among pilots, such as age, experience, and cognitive style. The predictive model also requires validation in actual flight conditions to determine its ecological validity. Future research should aim to address these limitations, generalize the findings, and integrate CPT data with other sensor inputs to provide a more comprehensive understanding of pilot performance.

Examining workplace safety for remote area nurses in Australia: a cross-sectional descriptive study.

Australia's remote health sector has chronic understaffing issues and serves an isolated, culturally diverse population with a high burden of disease. Workplace health and safety (WHS) impacts the wellbeing and sustainability of the remote health workforce. Additionally, poor WHS contributes to burnout, high turnover of staff and reduced quality of care. The issue of poor WHS in Australian very remote primary health clinics was highlighted by the murder of remote area nurse (RAN) Gayle Woodford in 2016. Following her death, a national call for change led by peak bodies and Gayle's family resulted in the development of many WHS recommendations and strategies for the remote health sector. However, it is unclear whether they have been implemented. The aim of this study is to identify which WHS recommendations have been implemented, from the perspective of RANs. A cross-sectional online survey of 173 RANs was conducted during December 2020 and January 2021. The survey was open to all RANs who had worked in a very remote (MM 7 of the Modified Monash (MM) Model) primary health clinic in Australia more recently than January 2019. A convenience sampling approach was used. The survey tool was developed by the project team using a combination of validated tools and remote-specific workplace safety recommendations. Broad recommendations, such as having a safe clinic building, safe staff accommodation, local orientation, and 'never alone' policy, were broken down into specific safety criteria. These criteria were used to generate workplace safety scores to quantify how well each recommendation had been met, and clustered into the following domains: preparation of staff, safe work environment and safe work practices. Descriptive statistics were used and the safety scores between different states and territories were also compared. Overall, the average national workplace safety score was 53% (standard deviation (SD) 19.8%) of recommendations met in participants' most recent workplace, with median 38.5% (interquartile range (IQR) 15.4-61.5%) of staff preparation recommendations, median 59.4% (IQR 43.8-78.1%) of safe work environment recommendations, and median 50.0% (IQR 30.0-66.7%) of safe work practices recommendations met. Within domains, some recommendations had greater uptake than others, and the safety scores of different states/territories also varied. Significant variation was found between the Northern Territory (57.5%, SD 18.7%) and Queensland (41.7%, SD 16.7%) (p<0.01), and between South Australia (74.5%, IQR 35.9%) and Queensland (p<0.05). Last, many RANs were still expected to attend after-hours call-outs on their own, with only 64.1% (n=107/167) of participants reporting a 'never alone' policy or process in their workplace. The evidence from this study revealed that some recommended safety strategies had been implemented, but significant gaps remained around staff preparation, fatigue management and infrastructure safety. Ongoing poor WHS likely contributes to the persistently high turnover of RANs, negatively affecting the quality and continuity of health care in remote communities. Variation in safety scores between regions warns of a fragmentation of approaches to WHS within the remote health sector, despite the almost identical WHS legislation in different states/territories. These gaps highlight the need to establish and enforce a national minimum standard of workplace safety in the remote health sector.

Correlation between Fatigue and Quality of Life in Adolescent Oncology Patients in Jordan

Background Adolescence represents a distinct and multifaceted developmental stage characterized by profound physical and cognitive transformations. Adolescents undergoing cancer treatment frequently have unique needs that remain unmet, leading to a notable decline in their quality of life. Cancer treatment often results in problems like fatigue, which affects patients' quality of life. Assessing quality of life and fatigue among adolescent cancer patients is essential for enhancing nursing care and improving outcomes. Objective This study aimed to investigate the correlation between fatigue and quality of life among adolescent cancer patients in Jordan. Methods A “cross-sectional” study was performed, with the participation of 127 Jordanian adolescent cancer patients, and data was collected through a nameless online survey of Jordanian adolescent cancer patients. The study commenced in February 2024 and concluded in June 2024. Demographic data and responses from two self-reported questionnaires—the Arabic versions of “Pediatric Quality of Life Inventory” “Multidimensional Fatigue Scale” and “Generic Core 4.0”—were collected. Descriptive statistics of means, frequencies, standard deviations, and percentages were used with demographics while inferential statistics were conducted using independent t-tests, Spearman's rank correlation coefficients, and Kruskal-Wallis tests in SPSS, version 26. Results Significant and potent correlations were found between various types of fatigue “general, sleep/rest, cognitive, and total” and quality of life “physical, emotional, social, school, psychosocial health”. Notably, the total fatigue scores showed a potent correlation with the total summary scores (r=0.946), with a p-value significant at the &lt;0.001 level for all correlations, indicating that adolescents with cancer experienced high fatigue and low quality of life. Conclusion The study demonstrated a potent link between fatigue and quality of life. The study's outcomes can help enhance guidelines for routine evaluation of fatigue and quality of life by nurses and healthcare providers in adolescent cancer patients to implement and evaluate interventions aimed at reducing fatigue in patients, highlighting fatigue as a significant concern. Future research should explore interventions such as exercise, leisure activities, and sleep to alleviate fatigue. Longitudinal research is essential to assess fatigue at diverse times of the day and week; this could help develop tailored fatigue management strategies to augment the quality of life among adolescent oncology patients.

Physical therapy for the management of global function, fatigue and quality of life in amyotrophic lateral sclerosis: systematic review and meta-analyses.

To critically evaluate the effectiveness of physical therapy interventions in improving global function, quality of life and fatigue in individuals with amyotrophic lateral sclerosis (ALS). Systematic review and meta-analyses. MEDLINE, EMBASE, Cochrane Library (CENTRAL) and Physiotherapy Evidence Database (PEDro) were searched through 31 January 2023. We included randomised clinical trials (RCTs) that compared physical therapy interventions that act on global function, fatigue and quality of life in individuals with ALS with any other non-physiotherapeutic methods and techniques, placebo or non-intervention. The primary outcome measure was the evaluation of global function. Secondary outcomes were quality of life, fatigue and adverse events. Two independent authors used a researcher-developed extraction form and the Rayyan software to search, screen and code included studies. The risk of bias was assessed using the PEDro scale. Meta-analyses were conducted employing random effects. Outcomes were succinctly presented in Grading of Recommendations, Assessment, Development and Evaluation evidence profiles. Our searches identified 39 415 references. After study selection, three studies were included in the review. Such studies involved 62 participants with a mean age of 54.6 years. In the evaluated trials, 40 were male, while 22 participants were female. Regarding the type of onset of the disease, 58 participants had spinal onset of ALS, and four had bulbar. Physical therapy intervention may improve the global function of individuals with ALS in the short term; however, clinically, it was inconclusive. In terms of quality of life and fatigue, physical therapy intervention is not more effective than control in the short term. Adverse events are not increased by physical therapy intervention in the short term. Due to significant methodological flaws, small sample sizes, wide CIs and clinical interpretation, our confidence in the effect estimate is limited. CRD42021251350.

Managing fatigue transdiagnostically: a qualitative study among people with chronic conditions on optimizing daily activity

Purpose To explore fatigue and physical activity behavior experiences and management, with an emphasis on activity pacing among adults with chronic conditions. Materials and Methods Semi-structured interviews were conducted with 15 adults with chronic conditions and the symptoms of chronic fatigue who had either received or not received fatigue management advice. Interviews were audio-recorded and transcribed verbatim, then analyzed using reflexive thematic analysis. Results Participants reported barriers to fatigue management such as overactivity, mental health issues, and workplace challenges. Additionally, they highlighted rest, restful activities, and supportive social environment as facilitators of effective fatigue management, along with the importance of nutrition and physical activity. In some cases, there were conflicting experiences with social environment and physical activity. Activity pacing was identified as a promising solution and participants recommended several strategies for future consideration. Conclusions Participants identified fatigue as a significant denominator in daily living and recognized the importance of activity pacing in fatigue management. Through reflective processes, they uncovered crucial factors for effective fatigue management, highlighting a multidimensional, interdisciplinary, and tailored approach to activity pacing as a promising solution. Further research should explore clinicians’ perspectives of a multidimensional fatigue management approach to further support optimal intervention design.