Tooth avulsion is one of the common types of orofacial and dental trauma that frequently occurs in sports and requires prompt management and a good treatment plan to achieve satisfactory outcomes. The aim of this case report is to present an overview of the tooth replantation using a trepanation procedure that has not been previously discussed in any formal publication. A clinical case concerning the management of tooth avulsion applying trepanation principles is narratively described along with a follow-up on the periodontal tissue condition after 2 years of treatment. The findings revealed the absence of inflammatory resorption, the most severe form of resorption typically seen within the initial 2 years following the replantation of an avulsed tooth. Nonetheless, caution should still be exercised regarding signs of surface root resorption, which although more favorable than inflammatory resorption and replacement resorption, should not be overlooked. Trepanation has demonstrated its ability to prevent inflammatory resorption for a minimum of 2 years post-replantation with no indication of ankylosis observed. Further investigation into trepanation is warranted to delve into the potential advantages of this procedure.
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