The chemical weathering processes and sedimentary source evolution since the Younger Dryas (YD) in the low-latitude arid continental margin have been investigated. Two sediment cores, MK07G and MK09G, were retrieved from the Makran continental margin in the northern Arabian Sea and subjected to analyses of major and trace elements, along with AMS14C dating. The results show that since the YD, the weathered parent rocks of Makran sediments have remained relatively stable, predominantly consisting of felsic rocks, with some contributions from mafic rocks. The Makran sediments exhibit initial to moderate weathering, with no discernible effects from grain size sorting or disturbances from sediment recycling, indicating primary deposition. Significant contributions of terrigenous eolian dust from surrounding continents (e.g., the Indian subcontinent, Arabian Peninsula, and northeastern Africa) were identified, along with riverine inputs from the Dasht River and fine-grained components from the Late Pleistocene Indus delta sediment, as well as proximal basin sedimentation. The evolution of sediment sources in the study area is significantly influenced by the Indian Monsoon and westerly wind systems, with intensified monsoon phases and westerly conditions correlating with increased fluvial input. Furthermore, chemical weathering processes since the YD are closely linked to local precipitation patterns, where intensified rainfall enhances weathering intensity. Records from the Makran continental margin indicate a teleconnection between chemical weathering and sedimentary processes in the Arabian Sea and Bond events in the North Atlantic, highlighting the extensive influence of Northern Hemisphere climate fluctuations.