Major Segments Research Articles

A model of the earthquake cycle along the Gofar oceanic transform faults

The Gofar oceanic transform fault at the East Pacific Rise has one of the best seismic cycles recorded by modern instruments. The timing, location, and magnitude of major earthquakes (Mw>5.5) have been well constrained by data from global seismic networks for the past 30 years. The earthquake interval is short, about 3-5 years. Several segments have already experienced 5 cycles since 1995, when the seismic network was good enough for surface wave relocation. Two ocean bottom seismometer deployments (2008-2009, 2021-2023) also provide constraints on the seismic properties on the fault. This makes Gofar an ideal place to study earthquake cycles. Here, we developed a model for the seismic cycle along the Gofar transform fault using a semi-analytical approach for rapidly calculating 3D time-dependent deformation and stress caused by screw dislocations embedded within an elastic layer overlying a Maxwell viscoelastic half-space. The 160-km long fault is divided into three major segments with six asperities. Our model simulates the earthquake pattern on this fault for the past 30 years. Most of the time, each asperity ruptured as a large earthquake every 3-5 years. Most segments have a nearly constant Coulomb stress threshold of 2-3 MPa, providing optimal conditions for the forecasting of future earthquakes along Gofar. For three cases that deviated from this simple regular pattern, a large earthquake occurred with a centroid location between two asperities. This is likely due to concurrent rupture that involved both asperities. We also modeled surface deformation with different elastic layer thicknesses and mantle viscosities. Even though most deformation is in the horizontal direction, the difference in both horizontal and vertical directions between models can be as large as a few centimeters per year. Several seafloor geodesy methods can be used to differentiate between models, and seafloor pressure might be the most appropriate one at this remote location.

Escaping isolation: Harry Truman and the sources of modern presidential authority

AbstractBetween 1947 and 1949, Harry Truman had all the markings of an isolated president. He was unelected, faced a Congress controlled by opposition Republicans, and was opposed by major segments of his own party. Yet unlike other presidents in similar isolated positions, Truman managed to overcome these institutional obstacles and was successfully elected to his own term in office and pulled the Democrats into majorities in both houses of Congress. This article examines the conditions that allowed Truman to escape his political and institutional isolation, arguing not only that Truman gives us a clear view of the strong constitutional basis of presidential power in the modern era, but also that extraconstitutional developments enabled Truman to do what no other isolated president was able to accomplish.

Impact of Driving Timing and Road Types on the Operating Regions of Electric Two-wheeler Powertrain Components under Indian Road Conditions

Among the different classes of electric vehicles (EVs), electric two-wheelers (E2Ws) are securing more enticement towards the commutator for regular usage due to their higher suitability in the heterogeneous traffic conditions of India. However, the driving range of the E2Ws is the major concern in increasing its penetration rate in road transportation. To eradicate the range anxiety of commutators by redesigning the current E2W powertrain configuration, this study strives to insights into the operational limits of powertrain elements such as the battery and motor in E2W under multiple operational circumstances such as driving style, pavement, and ambient conditions. Regarding this, the E2W with data acquisition system (DAC) connected with an onboard diagnosis (OBD) port is utilized to acquire the data related to powertrain components and vehicles for four driving trips (trips 1–4) under three major road segments (Rural, expressway, and urban) of India. The operating and computed performance metrics, comprising battery voltage and current, state-of-charge (SOC), energy consumption, motor current, speed, efficiency, and so on, are then compared throughout driving trips and road segments. The mean velocity of E2W for trips 1 to 4 is 31.91, 33.68, 39.03, and 35.58 km/h, respectively. The results disclosed that total energy consumption and energy consumption per km. are higher during trip 3 due to higher average vehicle speed. Also, it has a higher depth-of-discharge (DOD) of 83.91 % than other driving trips. Further, a higher rate of SOC drop, energy consumption and battery temperature rise are found at highway road segments.

Flood Detection and Monitoring using IOT

One of the most destroying characteristic pf natures that can happen any place in the globe is flooding. In consideration to keep an eye on the surge circumstance particularly in a low line range, a framework was put and developed to track the Dam water level, Door opening status and precipitation level in real-time. A application-based data source for the open, reacting to their require for data on water conditions and flooding, and a Status page for data approximately flooding between the included specialists and specialists to move forward their obligations and participation are the two essential objectives of the made framework. A sensor organizes, a processing/transmission unit, and a database/application server make up the made framework. With the offer assistance of a remote sensor arrange that communicates with the application server over versatile Common Parcel Radio Benefit (GPRS), it is conceivable to remotely screen this real-time information of water condition. To encourage communication between the application server a microcontroller will be utilized. Ultrasonic sensors will be utilized to bring the correct level of the water in the dam. The entryway opening status will be picked up through a few sensors like water sensors and rain sensors. The versatile application which is made and associated with a few IOT Sensors will be having two major segments i.e. Flood Status and Emergency services. A few crisis administrations like healing centres, transport will be included in this application which will be valuable in the overwhelmed circumstances and post overflowed circumstances.

AN APPROACH FOR LUNG CANCER DETECTION AND CLASSIFICATION USING LENET-DENSENET

Lung cancer is a malicious disorder that affects millions of people around the globe. Premature detection and classification of malignant cells can gradually improve the rate of survival of the patients. The study proposed an innovative strategy for lung cancer identification and classification by utilizing the hybrid deep learning (DL) technique. The presented strategy contains two major parts, segmentation and classification. Attention gated (AG) network is used for segmenting the affected regions. AGs guide a method’s attention to significant regions while repressing the activation of features in non-related fields. This augments the model’s representative influence without significantly increasing computing cost or the number of model parameters. For the lung cancer classification, by combining the architectures of LeNet and Dense Convolutional Network (DenseNet), the proposed LeNet–DenseNet was developed. LeNet and DenseNet are two popular CNN architectures known for the classification of images. LeNet comprises alternating and convolutional layers, followed by fully connected layers. As per the idea of densely connected layers, each layer in DenseNet, which is a recent CNN architecture, is associated with other layers in a feed-forward fashion. This allows for better feature reuse and gradient flow and lessens the parameter count. The findings stated that the proposed method outperforms when compared to other traditional strategies corresponding to specificity, sensitivity and accuracy. The presented approach assists in early-stage detection of high-accuracy lung cancer, which is considered crucial for the treatment procedures in time. The findings stipulated that the presented LeNet–DenseNet model procured accuracy of 94.8%, sensitivity of 96.8% and specificity of 93.5%.

The Evolution of Real Estate: Digital Marketing's Influence

Digital marketing has become an essential trend for real estate firms in India, driven by improved network infrastructure and the widespread use of smart phones. This research examines the various digital marketing strategies employed by real estate companies and evaluates their effectiveness. With potential clients increasingly conducting their own research online, digital marketing has become a vital component of overall marketing efforts. Enhancing brand image and facilitating efficient customer communication are imperative for real estate organizations, and this requires fortifying their online presence on search engines, corporate websites, and social media platforms. Digital marketing, particularly through social media platforms, has a significant influence on the real estate industry, just like it does on many other sectors. In today's real estate marketing, websites, Face book, Integra, and YouTube have become indispensable resources. There is little study that focuses especially on social media management within India's real estate business, despite the fact that economic growth and population increase are the driving forces behind Indonesia's real estate market. Major segments in the real estate market include land, residential, commercial, and industrial properties, as well as real estate investment trusts, undeveloped land, and vacation homes. In the fiercely competitive real estate landscape, agents must do more than merely acquire a license—they need to embrace the digital innovations reshaping property transactions. Integrating digital marketing fully into real estate services is imperative. To meet the increasing demand for sustainability, real estate firms must develop digital expertise and skills to deliver impactful and efficient digital marketing solutions.

Assessing the Performance and Flower Quality of Dendrobium Varieties Grown Under Shade-net in Konkan Region

Dendrobium orchids are highly valued for their aesthetic appeal and durability, constituting a major segment of the global orchid market. A study was conducted in the Konkan region of Maharashtra (India) to determine the most suitable varieties for the specific climatic conditions of this area. The research was carried out under shade-net condition at the Hitech Nursery, College of Horticulture, Dapoli, in a Randomized Block Design (RBD) that included twelve varieties and thrice replications. The research revealed significant differences in various characteristics, including the timing of inflorescence emergence, spike length, the number of florets per spike, as well as flower length, diameter, and overall lifespan among different cultivars. During the findings, ‘Areedang Blue’ showed early inflorescence emergence as well as flowering (14.5 days), while ‘Thongchai Gold x Udom Yellow’ had late inflorescence emergence and flowering (19.89). The variety ‘White 5N’ was particularly noted for its extended spike length (57.60 cm) and consistently high florets per spike (10.66), while ‘Sonia Red’ was recognized for having the longest flower lifespan (62.59 days) with good flower size. Conversely, certain varieties such as ‘King Dragon’ and ‘Burana Jade x Madam Vipa’ did not expressed their potential to the local environment. This investigation offers prime information for the selection of best Dendrobium varieties suitable for cultivation in Konkan region under shade-net condition.

Study of variations in the origin and branching of the human dorsal pancreatic artery

In surgical practice, the human pancreas is conventionally divided into two major anatomical and surgical segments: the right (cephalo-cervical) and the left (corpore-caudal). Both of these segments are abundantly supplied with blood. The artery-first approach is widely used in pancreatic resections to avoid venous stasis and achieve reduced blood loss. The dorsal pancreatic artery participates in the blood supply of both segments with its branches, which makes its anatomical study relevant and promising for clinical medicine. The aim was to describe the main branches of the dorsal pancreatic artery and to determine the frequency of their occurrence in the studied cases. Materials and Methods. The work was performed on archival fixed material (n = 60) of duodenum-pancreas-spleen organ complexes with extra-organ vessels taken from the collection of the Department of Anatomy, RyazSMU. All organ complexes belonged to mature age people without pronounced pathology of the organs of the investigated area. The division by sex was not performed. Results. The dorsal pancreatic artery was identified in all cases studied. Most often (n = 40; 67%) it originated from the branches of the ventral trunk, less often (n = 18; 30%) it was a branch of the superior mesenteric artery and in two cases (3%). Despite the place of origin, its trunk diameter averaged 1.8 mm (min 1.6; max 2.0). The branches of this artery were most often directed towards the gland body (85% of cases), less often - towards the head (15%). Conclusion. The dorsal pancreatic artery is the main artery feeding the body and tail of the human pancreas. In the present study, its branches were more frequently recorded towards the body of the gland, despite the origin of the vessel. Despite the accumulated anatomical and clinical knowledge about the peculiarities of the origin and branching of the human dorsal pancreatic artery, the understanding of the principles of the direction of its branches remains open to researchers.

Engineering the L-tryptophan metabolism for efficient de novo biosynthesis of tryptophol in Saccharomyces cerevisiae

Tryptophol (IET) is a metabolite derived from L-tryptophan that can be isolated from plants, bacteria, and fungi and has a wide range of biological activities in living systems. Despite the fact that IET biosynthesis pathways exist naturally in living organisms, industrial-scale production of IET and its derivatives is solely based on environmentally unfriendly chemical conversion. With diminishing petroleum reserves and a significant increase in global demand in all major commercial segments, it becomes essential to develop new technologies to produce chemicals from renewable resources and under mild conditions, such as microbial fermentation. Here we characterized and engineered the less-studied L-tryptophan pathway and IET biosynthesis in the baker’s yeast Saccharomyces cerevisiae, with the goal of investigating microbial fermentation as an alternative/green strategy to produce IET. In detail, we divided the aromatic amino acids (AAAs) metabolism related to IET synthesis into the shikimate pathway, the L-tryptophan pathway, the competing L-tyrosine/L-phenylalanine pathways, and the Ehrlich pathway based on a modular engineering concept. Through stepwise engineering of these modules, we obtained a yeast mutant capable of producing IET up to 1.04 g/L through fed-batch fermentation, a ~ 650-fold improvement over the wild-type strain. Besides, our engineering process also revealed many insights about the regulation of AAAs metabolism in S. cerevisiae. Finally, during our engineering process, we also discovered yeast mutants that accumulate anthranilate and L-tryptophan, both of which are precursors of various valuable secondary metabolites from fungi and plants. These strains could be developed to the chassis for natural product biosynthesis upon introducing heterologous pathways.

Genome-Wide Association Studies (GWAS) and Transcriptome Analysis Reveal Male Heterogametic Sex-Determining Regions and Candidate Genes in Northern Snakeheads (Channa argus).

The Northern snakehead (Channa argus) is a significant economic aquaculture species in China. Exhibiting sexual dimorphism in the growth rate between females and males, mono-sex breeding holds substantial value for aquaculture. This study employed GWAS and transcriptome analysis were applied to identify sex determination genomic regions and develop sex-specific markers. A total of 270 single-nucleotide polymorphisms (SNPs) and 31 insertion-deletions (InDels) were identified as being sexually dimorphic through GWAS and fixation index (Fst) scanning. Based on GWAS results, two sex-specific InDel markers were developed, effectively distinguishing genetic sex for XX females, XY males, and YY super-males via (polymerase chain reaction) PCR amplification. A major genomic segment of approximately 115 kb on chromosome 3 (Chr 03) was identified as the sex-determination region. A comparative transcriptome analysis of gonads for three sexes identified 158 overlapping differentially expressed genes (DEGs). Additionally, three sex-related candidate genes were identified near the sex determination region, including id2, sox11, and rnf144a. Further studies are required to elucidate the functions of these genes. Overall, two sex-specific InDel markers support a male heterogametic XX/XY sex-determination system in Northern snakeheads and three candidate genes offer new insights into sex determination and the evolution of sex chromosomes in teleost fish.

On the Billefjorden fault zone in Garmdalen, central Spitsbergen: implications for the mapping of major fault zones during geological fieldwork and for the tectonic history of Svalbard.

The present contribution reexamines the geometry of a segment of a presumably long-lived fault in Svalbard, the Balliolbreen Fault segment of the Billefjorden Fault Zone, along which presumably two basement terranes of Svalbard accreted in the early-mid Paleozoic after thousands of kilometers strike-slip displacement. We performed structural fieldwork to Billefjorden in central Spitsbergen and interpreted satellite images. Field observations demonstrate that the Balliolbreen Fault formed as a top-west thrust fault in the early Cenozoic and that weak sedimentary units such as shales of the Lower Devonian Wood Bay Formation and coals of the uppermost Devonian-Mississippian Billefjorden Group partitioned deformation, resulting in significant contrast in deformation intensity between stratigraphic units. For example, tight early Cenozoic folds are localized in shales of the Wood Bay Formation and contemporaneous top-west brittle-ductile thrusts within coals of the Billefjorden Group, whereas Pennsylvanian deposits of the Hultberget (and/or Ebbadalen?) Formation are simply folded into gentle open folds. Rheological contrasts also resulted in the development of décollements locally, e.g., between tightly folded strata of the Wood Bay Formation and Billefjorden Group and flat-lying, brecciated limestone-dominated strata of the Wordiekammen Formation. Despite the limited quality and continuity of outcrops in the area, the eastward-thickening character (i.e., away from the fault) of Pennsylvanian deposits of the Hultberget, Ebbadalen, and Minkinfjellet formations suggests that the fault did not act as a normal fault in Pennsylvanian times. The study suggests that strain partitioning of early Cenozoic Eurekan contraction alone may explain the deformation patterns in Paleozoic rock units in central Spitsbergen, i.e., that Late Devonian Svalbardian contraction is not required, and that a major segment of the Billefjorden Fault Zone formed in the early Cenozoic. The present work illustrates the crucial need for interdisciplinary approaches and composite educational backgrounds in science.

Quantifying the Pabu Normal Fault Scarp, Southern Tibetan Plateau: Insights into Regional Earthquake Risk

The location of the main boundary fault of the Yadong-Gulu Rift (YGR) shifts from the east side in the southern segment to the west side in the northern segment. The Nyemo Graben Group (NGG) connects the southern and northern segments of the YGR and provides clues for understanding the migration of boundary fault locations along the YGR. However, the NGG has received very little attention. In this study, we map the geometry of the Pabu normal fault, which is the boundary fault of the westernmost graben in the NGG, using high-resolution remote sensing images. We then utilized a digital elevation model (DEM) with a spatial resolution of 1 m. Morphometric parameters such as scarp height, width, and slope were obtained from elevation profiles in three typical deformation regions. Our results reveal a fault segment approximately 3 km long that links the southern and northern segments of the Pabu Fault. Each fault segment could be a major segment. Furthermore, based on regional tectonic activity, the Pabu Fault has the potential to produce an earthquake with a magnitude of around M 6.7.

Do the global trade fair organizers ensure sustainable development?: A comparative analysis between venue-bound and non-venue-bound organizers

This study examines the sustainable development approaches implemented by global trade fair organizers (TFOs). Six TFOs, including venue- and non-venue-bound organizers, were selected based on their revenue rankings. This study considers the environmental, social, and economic aspects of sustainability as major categories and segments them into 12 detailed items. The results indicate that most of the TFOs under study have a strong track record of environmental, social, and economic sustainability. However, strategies differ depending on TFOs’ venue ownership. Non-venue-bound organizers focus on policies that can be implemented during events, whereas venue-bound organizers are likely to adopt strategies within the venue. This study has both theoretical and practical implications for TFOs striving to achieve global competitiveness by adopting sustainability strategies. This study contributes to the literature by considering comprehensive sustainability dimensions and provides insights for further research and policy development in the exhibition industry.

One Billion Years of Stability in the North American Midcontinent Following Two‐Stage Grenvillian Structural Inversion

AbstractThe North American craton interior preserves a >1 Ga history of near surface processes that inform ongoing debates regarding timing and drivers of continental‐scale deformation and erosion associated with far‐field orogenesis. We tested various models of structural inversion on a major segment of the Midcontinent Rift along the Douglas Fault (DF) in northern Wisconsin, which accommodated ≳10 km of total vertical displacement. U‐Pb detrital zircon and vein calcite Δ47/U‐Pb thermochronometry from the hanging wall constrain the majority of uplift (≳8.5 km) and deformation to 1052–1036 Ma during the Ottawan phase of the Grenvillian orogeny. Combined U‐Pb zircon dates, Δ47/U‐Pb calcite thermochronometry, and field data that document syn‐ to early post‐depositional deformation in the footwall constrain a second stage of uplift (1–1.5 km) ca. 995–980 Ma during the Rigolet phase of the Grenvillian orogeny. A minor phase of Appalachian far‐field orogenesis is associated with minimal thrust reactivation. Our combined analyses identified the 995–980 Ma Bayfield Group as a Grenvillian foreland basin with an original thickness 0.5–2 km greater than currently preserved. By quantifying flexural loading and other subsidence mechanisms along the Douglas Fault, we identify dynamic subsidence as a mechanism that could be consistent with the development of late‐Grenvillian transcontinental fluvial systems. Minimal post‐Grenvillian erosion (0.5–2 km) in this part of the craton interior has preserved the Bayfield Group and equivalent successions, limiting the magnitude of regional erosion that can be attributed to Neoproterozoic glaciation.

The Digital Personal Data Protection Act, 2023: An Ambitious Government Step Towards Ensuring Its Wide Reach

This article is divided into three major segments. The initial section offers a concise overview of the requisite data protection laws in India, aiming to regulate and oversee the collection, processing and utilisation of personal data. The second section delves into an in-depth examination of the Digital Personal Data Protection Act, 2023 (the Act), accompanied by illustrative examples and its scope of applicability. The concluding part presents an analysis of the Act, focusing on its efforts and challenges in safeguarding wide reach as well as its implications for rural populations.

Redefining General Public Segment In Kustomfest: A Research On Visitor Motives In Attending A Kustom Kulture Festival

The Indonesian creative economy has experienced significant growth, with creative tourism emerging as a prominent driver. This study centers on Kustomfest, the Indonesian Kustom Kulture Festival, recognized as one of the largest Kustom Kulture hubs in the country. Between 2019 and 2023, there was a notable shift in the festival's audience composition, with the general public now constituting the majority segment. The research aims to identify and analyze the key motives driving the general public to attend Kustomfest, segment the market based on these motives, and examine each segment's sociodemographic profiles and behavioral characteristics. Three distinct market segments were identified, each motivated by different factors. Insights from this study can assist organizers of similar Kustom Kulture-related events in expanding creative tourism in Indonesia. By understanding visitor motivations and behaviors, event organizers can tailor marketing strategies, enhance visitor experiences, and capitalize on revenue opportunities from the general public segment. Recommendations are provided to attract, retain, and expand each segment through business model innovation, thus contributing to the sustained growth of Indonesia's creative economy. The findings highlight the importance of understanding visitor motivations and behaviors to maximize the impact of cultural events on the broader creative economy. These insights enable event organizers to foster growth in Indonesia's creative sector, ensuring that cultural festivals like Kustomfest continue to evolve and appeal to a diverse audience.

Неисполнение военнослужащим приказа начальника: концептуальный анализ состава ст. 332 УК РФ

The paper justifies the importance of observance of principles of unity of command and subordination in the Russian military service, which has become especially relevant after the start of the special military operation. The object of the study is major structural segments of the constituent elements of a crime stipulated by Art. 332 of the Criminal Code of the Russian Federation as amended and supplemented. The authors note the absence of unified approaches to the legal evaluation of some key concepts and definitions (order, commander, interests of the military service, etc.), which makes it difficult to qualify the committed act and results in fragmented law enforcement practice. The article identifies conflicts of and gaps in applicable criminal laws in this sphere and brings forward recommendation to eliminate them.

Generation Z - factors predicting decline in purchase intentions after receiving negative environmental information: Fast fashion brand SHEIN as a case study

Although Generation Z is known for its ethical and conscientious values, they are a major consumer segment of SHEIN fashion, a leading non-sustainable brand. This study explores how negative environmental information influences Generation Z's purchase intentions toward SHEIN. The findings of a survey among 607 SHEIN consumers reveal that participants lack environmental knowledge about fashion, have a medium sense of responsibility and have medium materialistic motivations. Following exposure to environmental information, negative attitudes toward SHEIN, along with perceived betrayal, were positively correlated with reduced purchase intentions. This research extends the Theory of Planned Behavior by integrating generational attributes and highlights the practical impact of negative information on reducing unsustainable consumption. This provides valuable insights for both academic discourse and marketing strategies targeting this digitally-native cohort.

Identification of Babesia microti immunoreactive antigens by phage display cDNA screen.

Human babesiosis is a malaria-like illness caused by protozoan parasites of the genus Babesia. Babesia microti is responsible for most cases of human babesiosis in the United States, particularly in the Northeast and the Upper Midwest. Babesia microti is primarily transmitted to humans through the bite of infected deer ticks but also through the transfusion of blood components, particularly red blood cells. There is a high risk of severe and even fatal disease in immunocompromised patients. To date, serology testing relies on an indirect immunofluorescence assay that uses the whole Babesia microti antigen. Here, we report the construction of phage display cDNA libraries from Babesia microti-infected erythrocytes as well as human reticulocytes obtained from donors with hereditary hemochromatosis. Plasma samples were obtained from patients who were or had been infected with Babesia microti. The non-specific antibody reactivity of these plasma samples was minimized by pre-exposure to the human reticulocyte library. Using this novel experimental strategy, immunoreactive segments were identified in three Babesia microti antigens termed BmSA1 (also called BMN1-9; BmGPI12), BMN1-20 (BMN1-17; Bm32), and BM4.12 (N1-15). Moreover, our findings indicate that the major immunoreactive segment of BmSA1 does not overlap with the segment that mediates BmSA1 binding to mature erythrocytes. When used in combination, the three immunoreactive segments form the basis of a sensitive and comprehensive diagnostic immunoassay for human babesiosis, with implications for vaccine development.

A critical appraisal on the involvement of plant-based extracts as neuroprotective agents (2012-2022): an effort to ease out decision-making process for researchers.

The purpose of this review study is to provide a condensed compilation of 164 medicinal plants that have been investigated for their neuroprotective aspects by researchers between the years 2012 and 2022 which also includes a recent update of 2023-2024. After using certain keywords to retrieve the data from SCOPUS, it was manually sorted to eliminate any instances of duplication. The article is streamlined into three major segments. The first segment takes a dig into the current global trend and attempts to decrypt vital information related to plant names, families, plant parts used, and neurological disorders investigated. The second segment of the article makes an attempt to present a comprehensive insight into the various mechanistic pathways through which phytochemicals can intervene to exert neuroprotection. The final segment of the manuscript is a bibliometric appraisal of all researches conducted. The study is based on 256 handpicked articles based on decided inclusion criteria. Illustrative compilation of various pathways citing their activation and deactivation channels are also presented with possible hitting points of various phytochemicals. The present study employed Microsoft Excel 2019 and VOS viewer as data visualisation tools.