Major Lines Research Articles

The unappreciated centrality of ethnoracially mixed Americans to the nation’s demographic future

The ethnoracial future of the United States has been framed as a demographic binary: Whites vs. people of color. The argument here is that this binary distorts by failing to take into adequate account the rapidly growing group of Americans who have been raised in mixed minority and White families, the great majority of the total mixed population. The members of this group generally have distinctive social characteristics: socioeconomic advantages compared to minorities and social integration into milieus with many Whites, as revealed by relatively high rates of marriage to them. However, their identities often encompass their minority heritage. Accordingly, they straddle the society’s major ethnoracial fracture line, creating an in-between social space and connecting, through kinship and other close social relations, both of its sides. However, their numbers are distorted in public national population data, such as census data and population projections; and they are typically counted as part of the non-White population. The recently announced revision of the race/ethnic data standards for the census offers an opportunity to refashion public data in a way that illuminates the important role this mixed group is likely to play in the nation’s demographic future.

Spectroscopic study of late-type emission-line stars using the data from LAMOST DR6

Abstract Low-mass emission-line stars belong to various evolutionary stages, from pre-main-sequence young stars to evolved stars. In this work, we present a catalog of late-type (F0 to M9) emission-line stars from the LAMOST Data Release 6. Using the scipy package, we created a Python code that finds the emission peak at H-alpha in all late-type stellar spectra. A dataset of 38,152 late-type emission-line stars was obtained after a rigorous examination of the photometric quality flags and the signal-to-noise ratio of the spectra. Adopting well-known photometric and spectroscopic methods, we classified our sample into 438 infrared excess sources, 4,669 post-main-sequence candidates, 9,718 Fe/Ge/Ke sources, and 23,264 dMe sources. From a cross-match with known databases, we found that 29,213 sources, comprising 56 IR excess sources, 7,899 Fe/Ge/Ke stars, 17,533 dMe stars, and 3,725 PtMS candidates, are new detections. We measured the equivalent width of the major emission lines observed in the spectra of our sample of emission-line stars. Furthermore, the trend observed in the line strengths of major emission lines over the entire late-type spectral range is analyzed. We further classified the sample into 4 groups based on the presence of Hydrogen and Calcium emission lines. This work presents a large dataset of late-type emission-line stars which improves the current sample to study active phenomena in late-type stars.

Disposal of SARS-CoV-2 corpses: experiences of environmental health officers

BackgroundThough the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is no more of a public health emergency, the experiences from burying SARS-CoV-2 infectious dead bodies may remain with the workers. For Environmental Health Officers (EHOs), dealing with decedents during the SARS-CoV-2 outbreak may arouse strong feelings of pity, horror, repulsion, disgust, and anger at the tragedy. Therefore, this study aims to explore the experiences of EHOs in disposing off of confirmed or suspected SARS-CoV-2 fatalities in Ghana.MethodsUsing an 18-item interview guide, we gathered data from 27 EHOs from three regions of Ghana. We followed the steps in Descriptive Phenomenology in conducting the data analysis.Resultsi. EHOs were confronted with several occupational health and safety (OHS) hazards like physical and chemical injuries, threat of harm, and psychological harm, ii. The officers also faced severe shortage of personal protective equipment (PPE). Unfortunately, they were not provided with any form of psychological support during the period.ConclusionThe SARS-CoV-2 outbreak in Ghana exposed major fault lines in the health and safety/disaster and emergency preparedness of EHOs towards the burial of infectious disease dead bodies. Clearly, the disposal exercise failed to uphold the Sustainable Development Goals (SDGs) 4.4, 8.3, and 8.5, which advocate for the promotion of decent jobs for all.RecommendationGhana’s Ministries of Health, Local Government, and Sanitation and Water Resources need to attach Clinical Psychologists and security personnel to the disposal teams in future exercises to provide psychological support and security to the team. Though studies on the disposal of infectious bodies in Africa exist, very little is known about the experiences of EHOs in the disposal of SARS-CoV-2 dead bodies during the outbreak.

Simulating the Formation and Eruption of Flux Rope by Magneto-friction Model Driven by Time-dependent Electric Fields

Aiming to capture the formation and eruption of flux ropes (FRs) in the source active regions (ARs), we simulate the coronal magnetic field evolution of the AR 11429 employing the time-dependent magneto-friction model (TMF). The initial field is driven by electric fields that are derived from time-sequence photospheric vector magnetic field observations by invoking ad hoc assumptions. The simulated magnetic structure evolves from potential to twisted fields over the course of two days, followed by rise motion in the later evolution, depicting the formation of an FR and its slow eruption later. The magnetic configuration resembles an inverse S-sigmoidal structure, composed of the potential field enveloping the inverse J-shaped fields that are sheared past one another and a low-lying twisted field along the major polarity inversion line. To compare with observations, proxy emission maps based on averaged current density along the field lines are generated from the simulated field. These emission maps exhibit a remarkable one-to-one correspondence with the spatial characteristics in coronal extreme ultraviolet images, especially the filament trace supported by the twisted magnetic field in the southwest subregion. Further, the topological analysis of the simulated field reveals the cospatial flare ribbons with the quasi-separatrix layers, which is consistent with the standard flare models; therefore, the extent of the twist and orientation of the erupting FR is indicated to be the real scenario in this case. The TMF model simulates the coronal field evolution, correctly capturing the formation of the FR in the observed timescale and the twisted field generated from these simulations serves as the initial condition for the full MHD simulations.

Study of direct and indirect risk assessment of landslide impacts on ultrahigh-voltage electricity transmission lines

Ultrahigh-voltage electricity systems are a vital part of energy networks, often across wide regions passing through mountainous terrains. The instability of slopes forming tower foundations along transmission lines poses a large risk to the entire energy network. Moreover, the tower foundations along extra-high-voltage electricity transmission lines are a very special type of element that are also highly vulnerable to landslides. In this study, an integrative risk assessment framework, including a hazard assessment, vulnerability analysis for the specified element at risk, and consequence estimation, is proposed to quantify the direct and indirect risks of landslides to power transmission lines. The Yanzi landslide, where a tower of the major ultrahigh-voltage transmission line from Sichuan (western China) to Shanghai (eastern China) has just been constructed, is taken as a case study. The correlation between landslide displacement and tower structure tilting is studied. In terms of the precipitation return period, factors of safety, failure probability, and deformation are simulated. A physical vulnerability curve is fitted by assuming a Weibull relationship between the horizontal deformation (hazard intensity) of the landslide and the tower inclination ratio. The total risk is calculated as the sum of the direct and indirect losses, among which the potential indirect risk due to tower damage is much greater than the direct risk. This work demonstrates the importance of landslide treatment strategies along electricity transmission lines by considering the potential indirect risks. The risk assessment model of landslides affecting ultrahigh-voltage electricity transmission lines proposed in this study could be useful for other types of indirect landslide risk evaluations.

Cultural-Environmental Systems and the Archaeology of Climate Change and Social Complexity: Midwest and Southeast United States

The investigation of dynamic fully integrated cultural-environmental systems is one grand challenge facing archaeologists in this century. In the Midwest and Southeast United States, archaeologists recently increased their study of Mississippian social systems (ca. AD 1000–1600) in relationship to paleoclimate and paleoenvironmental data. Significant differences in chronological control between archaeological chronologies and paleoenvironmental records pose challenges to the study of cultural-environmental systems in this region and often result in equifinal results. Three major lines of paleoenvironmental records are reviewed: bald cypress tree-ring records, the Living Blended Drought Atlas (LBDA), and lake-bottom sediment cores. The strongest approaches include local and regional multiproxy environmental records from the same location as a well-investigated archaeological site(s) or region(s). In the rare case where the cores also encode a regional population history, it may be possible to develop stronger inferences that consider variation within and between communities and their vulnerability to climate change and environmental catastrophes.

Historical Foundations of Green Developmental Policies: Divergent Trajectories in United States and France

ABSTRACTIn recent years, many countries have adopted biodiversity offset policies to internalize the ecological impacts of land developments. Although national policies share the general principle of equalizing ecological harm with gain, there is substantial variation across programs regarding the institutional forms governing offsetting. In this paper, we compare biodiversity governance in the United States and France to reflect more broadly on the factors shaping divergent trajectories of green developmental policies. Both countries have some form of biodiversity offsetting in place, but the major fault line of difference is the more extensive use of market‐based instruments (MBI) in the United States. Using a historical lens, we argue that one important reason for this variation lies in the different legal‐institutional definitions of biodiversity. A narrower definition in the United States focused on individual species, versus a broader definition in France focused on ecosystems, has facilitated a more standardized biodiversity governance arrangement in the United States. Leveraging this standardization, biodiversity markets have expanded in the United States while similar efforts to institutionalize market mechanisms have struggled in France. The comparison allows us to draw insights into the challenges in greening economic development, particularly in showing how historical scientific, legal, and institutional structures condition policy outcomes.

Mapping Ecological Security Patterns Based on Ecosystem Service Valuation in the Qinling-Daba Mountain Area, China: A Multi-Scenario Study for Development and Conservation Tradeoffs

When focusing on biodiversity maintenance, ecological security pattern (ESP) planning gradually becomes a multi-objective planning strategy for sustainable development; wildlife conservation and ecosystem health maintenance should be balanced with local economic development and people’s livelihood enhancement goals. This study focuses on ESP mapping in the Qinling-Daba Mountain area, which is an ecologically significant and socioeconomically underdeveloped area. The tradeoff between conservation and development is made by varying the area of ecological sources and incorporating ecosystem service tradeoffs into ecological source identification through multi-scenario designation. ESPs under six scenarios were generated based on the minimum resistance model, and the important ecological corridors and strategic points in each scenario were identified and compared. The results show the following: (1) The scenario that sets around 30 percent of the study area as ecological sources maintains the integrity of natural ecosystems and leaves space for food and material supply to residents. (2) In this scenario, the ecological sources are connected by 60 corridors that cross 137 townships with high population densities (>100 people/km2) and intersect with major traffic lines at 71 points. Engineering, management, or education strategies must be taken in these townships or intersections to avoid human–wildlife conflicts. (3) The study area needs to construct both short (north–south) corridors linking proximate ecological sources for species’ daily movement and long (west–east) corridors connecting large and distant sources for species’ seasonal migration and gene flow. (4) The multi-scenario approach turns out to be an effective strategy for ESP planning with considerations for development–conservation tradeoffs.

Impact of Extreme Rainfall on High-Speed Rail (HSR) Delays in Major Lines of China

Abstract Punctuality monitoring and analysis aim to optimize resource allocation for enhancing rail traffic performance and quality. Adverse weather conditions, particularly heavy precipitation events, are recognized as significant drivers of delays and reduced punctuality of the rail system. This study addresses two key research questions using high-speed rail (HSR) as an example—what is the impact of rainfall on HSR’s delay and to what extent are HSR vulnerable to rainstorms. The data for the study were collected from the HSR on the major lines of eastern China in the rainy season of 2015–17 which lasted from May to October. High-resolution precipitation data are integrated with nonspatial HSR operational data using GIS to create composite grids covering buffer zones around HSR lines. These grids match the spatial scale of historical hourly precipitation data and enable regression analyses to assess how precipitation affects HSR operations. The results indicate that extreme rainfall significantly contributes to delays and reduced punctuality, with varying impacts observed across different HSR lines. Specifically, daily areal precipitation significantly delays services on the Hangzhou–Shenzhen and Nanjing–Hangzhou HSR lines. Rainfall intensity has a more pronounced impact on delay services of the Beijing–Shanghai HSR, while extreme precipitation most frequently affects the Shanghai–Nanjing and Jinhua–Wenzhou HSR lines. The case analysis enhances understanding of HSR vulnerability to heavy rainfall conditions and recommends regional adaptation strategies to manage climate-related uncertainties.

Trend in agricultural growth and cassava productivity in Nigeria (1961 – 2020)

This study analyzed the trend in agricultural growth and cassava productivity in Nigeria (1961 – 2020). Time series on variables of interest were sourced from the Central Bank of Nigeria (CBN) statistical bulletin, the National Bureau of Statistics (NBS), and FAOSTAT. The secondary data obtained were analysed using trend analysis, instability index, compound growth rate model, and the Granger causality test. The results showed that Nigeria’s agricultural output generally experienced an upward trend from 1960-2020. The findings also revealed a general increase in the output of cassava produced in an area in the country within the study period. The yield however experienced some relatively stable trend with mild fluctuations and a noticeable decline in 2013. Across the major policy line considered in this study, the pre-SAP era (1961 – 1985) had the lowest mean output, while the SAP and post-SAP era had the highest mean output of 24772.15 and 45181.94 respectively. The values of instability of production and land put under cassava cultivation are more pronounced in Period II [1986–1998] and Period III [1999–2020]. During period I, (Pre – SAP; 1961 – 1985), the compound growth rate (CGR) for production accelerated while yield stagnated with a CGR of 0.2%. In period II, (CGR for production (6.2%) and area (6.3%) for cassava accelerated; both CGR and instantaneous growth rate for yield experienced stagnation. For period III, there was an acceleration in output and area. There was unidirectional causality between production (output) and area under cultivation, agricultural growth and cassava production, agricultural growth and area under cassava cultivation at a 5% level of significance; while area under cassava cultivation and cassava productivity, productivity and area under cultivation exhibited a bi-directional causality at 5% significant level. The findings are compelling reasons for encouraging cassava production for sustainable food production in Nigeria as it is a versatile staple to address food security.

Thrombospondins: Conserved mediators and modulators of metazoan extracellular matrix.

This review provides a personal overview of significant scientific developments in the thrombospondin field during the course of my career. Thrombospondins are multidomain, multimeric, calcium-binding extracellular glycoproteins with context-specific roles in tissue organisation. They act at cell surfaces and within ECM to regulate cell phenotype and signalling, differentiation and assembly of collagenous ECM, along with tissue-specific roles in cartilage, angiogenesis and synaptic function. More recently, intracellular, homeostatic roles have also been identified. Resolution of structures for the major domains of mammalian thrombospondins has facilitated major advances in understanding thrombospondin biology from molecule to tissue; for example, in illuminating molecular consequences of disease-causing coding mutations in human pseudoachrondroplasia. Although principally studied in vertebrates, thrombospondins are amongst the most ancient of animal ECM proteins, with many invertebrates encoding a single thrombospondin and the thrombospondin gene family of vertebrates originating through gene duplications. Moreover, thrombospondins form one branch of a thrombospondin superfamily that debuted at the origin of metazoans. The super-family includes additional sub-groups, present only in invertebrates, that differ in N-terminal domain organisation, share the distinctive TSP C-terminal region domain architecture and, to the limited extent studied to date, apparently contribute to tissue development and organisation. Finally, major lines of translational research are discussed, related to fibrosis; TSP1, TSP2 and inhibition of angiogenesis; and the alleviation of chronic cartilage tissue pathologies in pseudoachrondroplasia.

Rest-frame Optical Spectroscopy of Ten z ∼ 2 Weak Emission-line Quasars

We present near-infrared spectroscopy of 10 weak emission-line quasars (WLQs) at redshifts of z ∼ 2, obtained with the Palomar 200 inch Hale Telescope. WLQs are an exceptional population of type 1 quasars that exhibit weak or no broad emission lines in the ultraviolet (e.g., the C iv λ1549 line), and they display remarkable X-ray properties. We derive Hβ-based single-epoch virial black hole masses (median value 1.7 × 109 M ⊙) and Eddington ratios (median value 0.5) for our sources. We confirm the previous finding that WLQ Hβ lines, as a major low-ionization line, are not significantly weak compared to typical quasars. The most prominent feature of the WLQ optical spectra is the universally weak/absent [O iii] λ5007 emission. They also display stronger optical Fe ii emission than typical quasars. Our results favor the super-Eddington accretion scenario for WLQs, where the weak lines are a result of a soft ionizing continuum; the geometrically thick inner accretion disk and/or its associated outflow is responsible for obscuring the nuclear high-energy radiation and producing the soft ionizing continuum. We also report candidate extreme [O iii] outflows (blueshifts of ≈500 and 4900 km s−1) in one object.

Resistance of Pseudomonas aeruginosa and Staphylococcus aureus to the airway epithelium oxidative response assessed by a cell-free in vitro assay.

The antibacterial oxidative response, which relies on the production of hydrogen peroxide (H2O2) and hypothiocyanite (OSCN-), is a major line of defense protecting the human airway epithelium (HAE) from lesions when infected. The in vitro studies of the oxidative responses are performed mainly by one-shot H2O2 exposure that does not recapitulate the complex H2O2/LPO/SCN- system releasing the reactive oxygen species in airway secretions. A cell-free in vitro assay mimicking this system has been described but was not fully characterized. Here, we comprehensively characterized the hourly H2O2/OSCN- concentrations produced within this in vitro assay and assessed the resistance of Pseudomonas aeruginosa and Staphylococcus aureus clinical strains to the HAE oxidative response. We found that H2O2/OSCN- were steadily produced from 7h and up to 25h, but OSCN- was detoxified in 15 minutes by bacteria upon exposure. Preliminary tests on PA14 showed survival rates at 1-hour post-exposure (hpe) to H2O2 of roughly 50% for 105 and 107 colony-forming unit (CFU)/mL inocula, while 102 and 104 CFU/mL inocula were cleared after one hpe. Thirteen clinical strains were then exposed, highlighting that conversely to P. aeruginosa, S. aureus showed resistance to oxidative stress independently of its antibiotic resistance phenotype. Our results demonstrated how this in vitro assay can be helpful in assessing whether pathogens can resist the antibacterial oxidative HAE response. We anticipate these findings as a starting point for more sophisticated in vitro models that could serve as high-throughput screening for molecules targeting the bacterial antioxidant response.

(Vittorio de Nora Award) When Solid State Semiconductor Physics and Devices Meet Photoelectrochemistry: From Growth and Interfacial Processes to Photovoltaics

I joined the CNRS solid-state physics laboratory near Paris in 1978, to work on the preparation of CdTe solar cells using close space sublimation (CSS) growth process. Thanks to some original discoveries, we were able to achieve a record yield of 10.5% for the time, but this research was gradually abandoned in France and in Europe. Yet it was this method that formed the basis of the technology developed with such success by first solar. So I was on the right track.However, it was in a different direction that I decided to go: semiconductor photoelectrochemistry, a rapidly developing field at the time. Here too, solar energy remained the backdrop, with the field opened up by Honda’s work on the photoelectrolysis of water. I thus began research into the mechanisms of charge transfer at semiconductor-electrolyte interfaces, keeping CdTe as my study material, enabling me to draw on my knowledge of solid-state devices to guide the analysis of its photoelectrochemical behavior in an original way. Our studies have focused on highlighting the energetic changes at interfaces under illumination during charge transfer reactions towards redox species in competition with corrosion reactions. We have demonstrated the role of adsorption and surface chemistry in these phenomena, with the result that photoelectrochemical properties can be optimized. Photoelectrochemistry is once again a highly topical field with artificial photosynthesis.In 1980 I discovered that CdTe layers could be deposited electrochemically in a simple beaker, as theorized by F.A. Kröger, without having to use much heavier vacuum processes.The electrochemical deposition of CdTe immediately became one of the major themes of my research, and remained so until the 2000s. The analysis of deposition mechanisms and their relationships to film properties were the subject of numerous publications and theses, with some outstanding results, in particular the synthesis of a new phase such as CdTe2, the study of as-grown semiconducting properties , the demonstration of epitaxial growth.This work gave rise to two major lines of research with far-reaching consequences. The first concerns the extension of electrochemical synthesis to other compound semiconductors of oxide type, with the discovery of the electrochemical synthesis of ZnO by cathodic reduction in the presence of oxygen, leading to materials of exceptional crystalline quality, suitable for epitaxial deposition. Depending on the experimental conditions, the forms obtained can range from nanocolumns to compact films. These results have opened a new avenue at international level. They led us to introduce them into the photovoltaic field for the formation of TCOs or hybrid matrices for dye cells. The second concerns the electrochemical synthesis of CuInGaSe2 (note CIGS), a ternary semiconductor of major industrial importance to photovoltaics. Initiated in the early 90s, this work involved both fundamental research and the creation of an industrial outlet. It led to the creation of a laboratory dedicated to photovoltaics with EDF in 2002, which succeeded in the creation of a start-up in 2009, NEXCIS, which achieved world-class performance in the field. This adventure has been the subject of a book chapter. Today, it continues with the creation of a new start-up, that I founded in 2021, that is using the electrodeposition technology to manufacture ultra-light, flexible, high-efficiency photovoltaic modules for new applications.This vision of the fundamental and underestimated interest of solution growth methods (electrochemistry or CBD) for the development of high-quality functional materials, particularly for photovoltaic conversion, has guided my entire scientific approach to date. The emergence of halogenated perovskite cells, also prepared in solution, has recently reinforced this approach as a way forward.Selected references:RECOMBINATION AND CHARGE-TRANSFER AT THE ILLUMINATED N-CdTe ELECTROLYTE INTERFACE - SIMPLIFIED KINETIC-MODEL ,LINCOT, D; VEDEL, J, JOURNAL OF ELECTROANALYTICAL CHEMISTRY 220 (1987) 179MECHANISM OF CHEMICAL BATH DEPOSITION OF CADMIUM-SULFIDE THIN-FILMS IN THE AMMONIA-THIOUREA SYSTEM - IN-SITU KINETIC-STUDY AND MODELIZATION, ORTEGABORGES, R; LINCOT, D, JOURNAL OF THE ELECTROCHEMICAL SOCIETY 140 (1993)3464.SOLAR-CELLS WITH IMPROVED EFFICIENCY BASED ON ELECTRODEPOSITED COPPER INDIUM DISELENIDE THIN-FILMS, GUILLEMOLES, JF; COWACHE, P; MASSACCESSI, S; THOUIN, L; SANCHEZ, S; LINCOT, D; VEDEL, J., Advanced Materials 6 (1994)379Mechanistic study of cathodic electrodeposition of zinc oxide and zinc hydroxychloride films from oxygenated aqueous zinc chloride solutions, Peulon, S; Lincot, D , JOURNAL OF THE ELECTROCHEMICAL SOCIETY 145 (1998)864Solution growth of functional zinc oxide films and nanostructures, Lincot, D., MRS BULLETIN 35(2010) 778From the Lab to Scaling-up Thin Film Solar Absorbers. Hariklia Deligianni, Lubomyr T. Roamnkiw, Daniel Lincot, Pierre-Philippe Grand. Book Chapter in Advances in Electrochemical Science and Engineering,XVIII (2018)

Late Palaeozoic high-K calc-alkaline to shoshonitic series magmatism and related W(–Mo–Cu–Au) metallogeny of the Kyrgyz Tien Shan, Central Asia

In the Kyrgyz Tien Shan, numerous high-K calc-alkaline to shoshonitic series intrusions are associated with the large fault system known as the ‘Major structural line of Tien Shan’, or ‘Nikolaev Line’. During the Carboniferous, this lineament represented a zone of intracontinental, possibly back-arc rifting associated with a north-dipping subduction, whereas in the Late Carboniferous to Permian it was part of a larger continental collision structure. These Late Paleozoic high-potassic intrusions comprise numerous intrusive phases that vary in composition from the early mafic (monzogabbro, monzodiorite) through intermediate (monzonite, syenite, quartz syenite) to late stage and more evolved (quartz monzonite, granodiorite, monzogranite, leucogranite–alaskite) members locally intersected by monzodiorite–porphyry and lamprophyre dykes. They can be related to low degrees (from ∼1–2 to 2–2.5 vol%) of partial melting of metasomatically enriched upper mantle followed by magma fractionation and emplacement at shallower crustal levels. In summary, the high-K magmas formed in continental- and post-collisional arc settings with a progressive input of crustal material. From the west to the east, the potassic intrusions contain progressively higher Nb and Y concentrations, reflecting their derivation in a post-collisional setting. The A-type granite signatures also become more distinct in this direction. This is consistent with the tectonic model implying the ‘scissor-like’ closure of the Late Paleozoic Turkestan palaeo-ocean from east to west. These high-potassic intrusions are accompanied by W–Mo–Cu–Au skarn/porphyry to Au(–W) replacement-style deposits, which are part of the extended Au (Au–W–Mo–Cu) metallogenic belt of Tien Shan. The association of skarn and porphyry-style W–Mo to Mo–Cu–Au–W mineralization defines these ‘porphyry–skarn’ systems as a distinct group containing strongly oxidized andradite-dominant skarns. An early W partitioning into magmatic–hydrothermal fluid, together with Mo and Cu, is typical of this magmatic–hydrothermal system and can be explained by an early H 2 O saturation of the parental magma. The late-stage mafic dykes including lamprophyres probably reflect the presence of another, but concealed, mafic intrusion releasing CO 2 and metals, such as Au, As, Sb, Bi and Te, into the hydrothermal mineral system.

High Rates of Early Septic Failure, but Low Rates of Aseptic Loosening After Revision Total Knee Arthroplasty With Contemporary Rotating-Hinge Prostheses

BackgroundThe purpose of this study was to determine implant survivorship and functional outcomes for revision total knee arthroplasty (rTKA) with contemporary rotating-hinge knee implants. MethodsA retrospective review identified 115 rTKAs using contemporary rotating-hinge implants from 2014 to 2018 for the treatment of instability (34, 30%), reimplantation after periprosthetic joint infection (PJI) (33, 29%), aseptic loosening (25, 22%), arthrofibrosis (14, 12%), periprosthetic fracture (4, 3%), osteolysis (4, 3%), and femoral component fracture (1, 1%). There were 70 women (61%), and the mean age was 67 years (range, 27 to 94). The mean follow-up was 3 years (range, 2 to 6). Kaplan-Meier analysis and Cox proportional hazard models estimated survivorship. ResultsThe re-revision rate was 20% (23 of 115) at an average of 18 months postoperatively. Re-revision indications included PJI (n = 14), aseptic loosening (n = 4), arthrofibrosis (n = 2), instability/malalignment (n = 1), femoral stem fracture (n = 1), and hinge mechanism disruption (n = 1). At 2 and 5 years, survivorship free from all-cause re-revision was 86 and 64%, and survivorship free from re-revision for aseptic loosening was 100 and 87%, respectively. Use of a rotating-hinge implant in reimplantation after PJI was a risk factor for subsequent re-revision (hazard ratio = 2.4, P = 0.046). On a radiographic review of unrevised rotating-hinges, there were major radiolucent lines around 2 femoral and 5 tibial components. The mean Knee Injury and Osteoarthritis Outcomes Score for Joint Replacement increased from 43 preoperatively to 60 at 1 year (P < 0.001). ConclusionsIn patients treated with a rotating-hinge implant for rTKA, there were relatively poor 2-year (86%) and 5-year (64%) survivorship free from all-cause re-revision, most commonly due to PJI. Midterm survivorship free from re-revision for aseptic loosening was modest (87%). There should be a goal to mitigate complications in complex rTKAs with rotating-hinge implants, namely PJI.

Intermittent Electrification with Battery Locomotives and the Post-Diesel Future of North American Freight Railroads

Changing attitudes, regulations, public policy, and international treaties concerning fossil fuels are likely to lead freight railroads toward carbon-neutral technologies, yet only electric traction matches the performance of diesel-electric locomotives. The tremendous power requirements of freight trains make efforts to reduce greenhouse gas (GHG) emissions challenging, but the prospect of 7.2 megawatt-hour battery-electric locomotives (BELs) offers promise, and intermittent electrification can facilitate battery charging. Train performance calculations under simulated real-world conditions show four 7.2 megawatt-hour BELs can power 8,000-ton trains up to 230 mainline miles unassisted, with average energy consumption of 12.5 watt-hours/ton-mile. This permits discontinuous electrification of major freight lines, leaving “gaps” of up to 200 mi to reduce capital costs, especially in rugged terrain or where the power grid is sparse. Massive onboard battery arrays and intermittent access to the electrical grid for traction power and recharging provide great energy savings by recycling energy now lost when traveling downhill or braking. A case study of a hypothetical Class I railroad found intermittent electrification with BELs more than 60% more cost-effective than contiguous electric districts, and dramatically reduced engine changes. To reduce railroad GHG emissions, governments must support technical development, show that electrification works in various North American settings, and develop institutional-financial frameworks to incentivize intermittent electrification with BELs, all in the context of massive environmental and capacity upgrades to electrical networks. Given proper assistance and incentives, early 21st century railroads may find discontinuous overhead-wire electrification offers great promise in operating terms.

Convolutional Non-Homogeneous Poisson Process and its Application to Wildfire Ignition Risk Quantification for Power Delivery Networks

To quantify wildfire ignition risks on power delivery networks, the current practice predominantly relies on the empirically calculated fire danger indices, which may not well capture the effects of dynamically changing environmental factors. This article proposes a spatio-temporal point process model, known as the Convolutional Non-homogeneous Poisson Process (cNHPP), and applies the model to quantify wildfire ignition risks for power delivery networks. The proposed model captures both the current (i.e., instantaneous) and cumulative (i.e., historical) effects of key environmental processes (i.e., covariates) on wildfire risks, as well as the spatio-temporal dependency among different segments of the power delivery network. The computation and interpretation of the intensity function are thoroughly investigated. We apply the proposed approach to estimate wildfire ignition risks on major transmission lines in California, using historical fire data, meteorological and vegetation data obtained from the National Oceanic and Atmospheric Administration and National Aeronautics and Space Administration. A comprehensive comparison study is performed to show the applicability and predictive capability of the proposed approach.

Unlocking the Potential of Industry 4.0 for Supply Chain Flexibility and Agility: A Systematic Literature Review

This paper reports on a comprehensive literature review using the Systematic Literature Review approach to improve agility and flexibility at the Sustainable Supply Chain Management (SSCM) level. The review identified 51 papers that satisfied the research criteria. The literature on SCM-level I4.0, flexibility, and agility was classified into four major research lines, namely interrelationships between SCM strategies, I4.0 technologies’ role in enabling Supply Chain Flexibility and Agility, barriers to achieving supply chain-level flexibility, and drivers to improve supply chain-level flexibility. Content analysis of the papers from each group was also provided, along with gaps detected and avenues for future research. The findings can help organizations understand how to leverage I4.0 practices and technologies to improve their flexibility and agility capabilities in the SSCM context, as well as identify potential drivers and barriers to their achievement.

Partial muscle splitting prepectoral breast reconstruction. A horizontal pectoralis major muscle splitting line parallel to the muscle fiber was marked at the upper portion of the muscle which covered the upper edge of the sizer. The muscle was partially elevated from the chest wall, and the manually fenestrated ADM was fixed to the edge of the splitting muscle and IMF.

Partial muscle splitting prepectoral breast reconstruction. A horizontal pectoralis major muscle splitting line parallel to the muscle fiber was marked at the upper portion of the muscle which covered the upper edge of the sizer. The muscle was partially elevated from the chest wall, and the manually fenestrated ADM was fixed to the edge of the splitting muscle and IMF.