Main Hotspots Research Articles

Bibliometric and visual study of narcolepsy from 2000 to 2023

BACKGROUND More studies explored the prevalence, causes, associated conditions, and therapeutic strategies of narcolepsy. With an increasing focus on understanding narcolepsy’s prevalence, associated conditions, and therapeutic strategies, there’s a notable absence of bibliometric analyses summarizing trends in research and identifying emerging areas of focus within this field. AIM To conduct a bibliometric analysis to investigate the current status and frontiers of narcolepsy. METHODS The documents related to narcolepsy are obtained from the Web of Science Core Collection database (WoSCC) from January 1st, 2000, to December 31th, 2023, and VOS viewer 1.6.16, and the WoSCC’s literature analysis wire were used to conduct the bibliometric analysis. RESULTS A total of 4672 publications related to narcolepsy were included, and 16182 authors across 4397 institutions and 96 countries/regions contributed to these documents in 1131 different journals. The most productive author, institution, country and journal were Yves Dauvilliers, Stanford University, United States, and Sleep Medicine, respectively. The first high-cited document was published in Nature in 2005 by Saper et al , and this research underscores the role of certain neurons in ensuring the stability of sleep-wake transitions, offering insights into narcolepsy’s pathophysiology. CONCLUSION In conclusion, the main research hotspots and frontiers in the field of narcolepsy are the diagnosis of narcolepsy, pathological mechanism of narcolepsy and the treatment of narcolepsy. More studies are needed to explore effective strategies for the diagnosis and treatment of narcolepsy.

Porifera Associated with Deep-Water Stylasterids (Cnidaria, Hydrozoa): New Species and Records from the Ross Sea (Antarctica)

Stylasterid corals are known to be fundamental habitat-formers in both deep and shallow waters. Their tridimensional structure enhances habitat complexity by creating refuges for a variety of organisms and by acting as basibionts for many other invertebrates, including sponges. Porifera represent crucial components of marine benthic assemblages and, in Antarctica, they often dominate benthic communities. Here, we explore the sponge community associated with thanatocoenosis, mostly composed of dead stylasterid skeletons, collected along the Western and Northern edges of the Ross Sea continental shelf. Overall, 37 sponge species were identified from 278 fragments of the stylasterid Inferiolabiata labiata, of which 7 are first records for the Ross Sea, 1 is first record for Antarctic waters and 2 are proposed as new species. Despite the high biodiversity recorded in this and previous studies on Antarctic deep-sea communities, we are still far from capturing the true richness of Antarctic benthic assemblages. Long-term research programs designed to improve the knowledge of the deep-sea fauna inhabiting Antarctic waters are needed to support successful management and conservation plans, especially in this area, considered one of the main marine diversity hotspots worldwide.

The Trypanosoma brucei tRNA methylome.

Herein, the Trypanosoma brucei procyclic form and bloodstream form tRNA methylome is reported as revealed by small RNA bisulfite sequencing. 5-Methylcytosines were identified at six unique positions with 54 total 5-methylcytosines revealed. The main hot spot for 5-methylcytosine in tRNA is the junction between the variable region and the T-arm.

The growing, resilient, inclusive and sustainable (GRINS) project for the development of life cycle inventory databases of beef cattle raised in Italy: The statistical datasets and the environmental assessment

Within the framework of the Growing, Resilient, Inclusive and Sustainable (GRINS) project (Spoke 1, WP3, Next Generation EU program), this work aims to overcome the absence of Italian beef cattle Life Cycle Inventory (LCI) datasets through a capillary analysis of several parameters. Specifically, the contribution to the environmental impact of livestock breeding of breed features (age, gender, weight, daily weight gain, breeding, feed intake and composition, milk and manure production), as well as stable management and crop cultivation was investigated. Statistical inventory datasets (84 in total) were developed for the predominant (<1 % population cut-off) beef cattle breeds in Italy.A key finding was the quantification of CH4 emissions from enteric fermentation (ranging from0.259 to 0.714 g kg−1 of live weight per day) and its contribution to the overall environmental impact of beef cattle breeding. The composition of feed rations emerged as critical, influencing both cattle emissions and environmental impacts associated with the cultivation and transport of raw materials. Intensive and langer breeds like Aubrac, Blond d'Aquitaine, Blue Belga, Charolaise, and Chianina, exhibited higher eco-indicator values compared to the extensive beef cattle breeds (Podolica, Highland, and Maremmana). The life cycle assessment identified several key impact categories (climate change, water use and ecotoxicity freshwater) mainly contributing to the total eco-indicator. Climate change (22.1 %) represented the greatest impact category, with beef cattle emissions over their lifespan averaging 9.3 Mg CO2-eq. Methane (enteric fermentation) and NH3 (manure management) emissions, as well as irrigation and pesticide use, represented the main hotspots. A comparative analysis evaluated the environmental footprint of Italian beef cattle against benchmarks outlined in the “Made Green in Italy” brand's Product Category Rules. This comparison revealed a 32.4 % reduction in total eco-indicator for Italian beef cattle, due to a significant decrease in freshwater ecotoxicity (−72.5 %), land use (−34.2) and climate change (−7.5 %).

Environmental, energy, and economic (3E) assessment of viticulture systems.

Given the current trends, it seems obvious that temperatures and atmospheric carbon dioxide levels will rise over the coming years. To deal with climate change, a gradual transition to more sustainable viticulture operations is required. It seems necessary to carry out accurate local studies for future projections. The purpose of the current study was to choose the best grape production system in Jowzan Valley, Malayer, Iran. This region was registered by FAO as a Globally Important Agricultural Heritage System (GIAHS) in 2018. This study seeks to answer the question: if climate change has occurred in the Malayer region, which of the traditional and trellis systems is more sustainable from economic, energy, and environmental aspects? The sixth phase of the Coupled Model Intercomparison Project (CMIP6) was used to project the climate parameters of Malayer in the past and the future. The output of climate models based on rainfall, temperature, and wind (as factors influencing grape yield) in the observation period of 1992-2021 (the base period) and forecasting the future period of 2021-2100 under three scenarios (SSP1-26, SSP2-45, and SSP5-85) were obtained. The determination of hotspots in terms of cost, energy, and environment for two production systems was done with the approaches of material and energy flow cost accounting (MFCA) and life cycle assessment (LCA). The results of these two approaches help us know which of the two systems are currently more sustainable in terms of economic, energy, and environmental aspects. Grape production in 1 hectare was chosen as a functional unit (FU). The system boundary included the foreground processes that the farmer was directly involved in managing. Grape data were collected in the crop year of 2021-2022 from the vineyards of Jowzan region. According to results, under SSP1-26, SSP2-45, and SSP5-85 scenarios, the annual mean temperature is expected to rise at rates of 0.27, 0.477, and 0.82°C 10a-1 in the future (2021-2100), respectively. From an economic point of view, labor was recognized as the main input. By changing the system from traditional to trellis, production costs can be expected to be halved. The main hotspot in terms of negative products was the loss of grapes during production or harvesting. Such conditions were also true in terms of energy. From the environmental aspect, on-farm emissions and electricity were identified as hotspots. These effects are greatly reduced in the trellis system compared to the traditional system. In the case of changing the system from traditional to trellis, these effects can be reduced to a reasonable extent by improving the efficiency of irrigation and fertilizer distribution through the irrigation system. According to the results obtained from the climate scenarios as well as the results of the economic, environmental, and energy evaluation of the two production systems, it can be concluded that the use of the trellis system can be more sustainable than the traditional system.

Combined Effects of Treatment and Sewer Connections to Reduce Future Microplastic Emissions in Rivers.

Global mitigation strategies are needed to reduce the amount of microplastics reaching our oceans via rivers. However, what strategies will be most effective, and when and where to implement these strategies is unclear. We applied the global water quality model MARINA-Plastics, covering 10,226 sub-basins worldwide, to assess the effects of different emission reduction strategies on microplastic inputs to rivers worldwide over the period 2010-2100, taking time steps of 10 years. We applied four scenarios: three focused on wastewater treatment technologies, ranging from high to low technology improvement levels, and one combining high technology in wastewater treatment with source-oriented measures. The results show that the combined strategy of high wastewater treatment and source-oriented measures is expected to be the most effective for reducing future microplastics in rivers on a global scale. By 2100, this combined strategy is expected to result in a 68% microplastic reduction in global rivers compared to 2010. African rivers will be the main hotspots, receiving more than five times more microplastics in 2100 than in 2010. In 2100, wear from car tires is expected to be the dominant source of microplastics globally. Our insights support the implementation of the European Green Deal and the realization of Sustainable Development Goal 6 (clean water).

Comparative analysis of manure treatment scenarios on climate change and eutrophication in the Baltic Sea

This study conducted a life cycle assessment (LCA) of manure management, identifying transportation as a major contributor to global warming and freshwater eutrophication impacts. Transporting substrates to the biogas plant was the main hotspot, highlighting a critical area for improvement. The findings emphasize the importance of method selection in geographically dependent assessments, especially in the Baltic Sea region. Characterization factors specific to Sweden revealed higher environmental impact values than those produced by the ReCiPe method, underscoring the need for regional differentiation in LCA. By optimizing manure management practices and enhancing nutrient distribution, impacts on both climate change and eutrophication can be significantly reduced, thereby lowering nutrient flow to the Baltic Sea. Combining these optimizations with transportation impact reductions further amplifies these environmental benefits, demonstrating that geographically tailored approaches in LCA offer essential insights for managing regional-scale effects.

The pyroptosis and fibrotic diseases: a bibliometric analysis from 2010 to 2024

BackgroundFibrosis is the ultimate, common pathological ending of most chronic inflammatory diseases and increases the chances of developing life-threatening illnesses. Pyroptosis, a newfound form of lytic programmed cell death initiated by the inflammasome, has received more and more attention because of its association with fibrotic diseases. Therefore, this study visualizes the connection between pyroptosis and fibrosis research through bibliometric methods, aimed at providing global research hits and tendencies in the field.MethodsWe collected and analyzed the articles on pyroptosis and fibrosis from 2010 to 2024 via Web of Science. Visual data analysis was performed for countries, institutions, authors, references, and keywords in the field using VOSviewer, CiteSpace software, the “Bibliometrix” R package, the bibliometric website (https://bibliometric.com/), and Excel software. We analyzed the data by utilizing the bibliometric review method.ResultsA total of 566 articles and reviews relating to pyroptosis and fibrosis were identified in the Web of Science. The number of publications in the domain has continued to grow since 2010. These scientific outputs were mainly from 129 countries/regions and 1919 institutions, particularly China (n = 423) and the USA (n = 83). More importantly, although China publishes a vast majority of articles, its centrality is lower than that of the USA (0.59 vs 0.61). Among the 3833 authors involved in this field, Feldstein, A. E. is the most prolific author. Shi, J. J. is the world’s most-cited author among the 12,143 authors in these academic journals. Frontiers in Immunology was a prolific contributor, and Nature was the most frequently cited journal. After analysis, Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death were the top-cited articles. The analysis of keywords displayed that pyroptosis, fibrosis, and pathways were the main research hotspots and frontier directions in recent years.ConclusionWe analyzed the characteristics of published articles and drew a fundamental knowledge structure on pyroptosis and fibrosis research via bibliometric analysis. The potential mechanism between fibrosis and pyroptosis is deeply tied to the current moment. Our findings can help researchers make clear the research status and value of fibrosis and pyroptosis and provide new directions for future research as soon as possible.

A bibliometric analysis and visualization of non-suicidal self-injury in adolescents.

Non-suicidal self-injury(NSSI)is a widespread occurrence among adolescents, and this behavior can bring serious consequences. In recent years, the prevalence of NSSI continues to rise, which has attracted the attention of many researchers. But currently there is no research exploring the overall research distribution of NSSI in adolescents through quantitative analysis. Therefore, it is necessary to understand the status of development and main research hotspots of NSSI in adolescents via bibliometric analysis. We searched the relevant studies from the Web of Science Core Collection(WoSCC)from January 1, 2014 to December 31, 2023. Using CiteSpace and VOSviewer visual analysis tools, we analyzed studies from the perspectives of country, region, institution, journal, author, and keywords. A total of 2177 studies related to NSSI in adolescents were included. USA and Harvard University were the leading country and institution in this research field. Penelope Hasking was the most prolific author. Frontiers in Psychiatry and the Journal of Affective Disorders were the most productive journals. The most high-frequency keywords were 'depression', 'mental health', 'emotion regulation' and 'borderline personality disorder'. 'mindfully', 'intervention', 'self-compassion' and 'ecological momentary assessment' were the emerging keywords. Exploring the relevant factors and mechanisms of comorbidities, identifying etiology and risk/protective factors, and finding the impact of NSSI on adolescents are the hot topics. Moreover, intervention measures and interdisciplinary collaborative research for NSSI in adolescents will emerge as frontiers in the future.

Environmental Sustainability Assessment of Tissue Paper Production

The environmental performance of tissue paper varies greatly based on factors such as the type of fibre used as the raw material, the production process and the fuels used to meet the energy requirements. One possible strategy to decrease greenhouse gas emissions in tissue production is the integration of pulp and paper mills and their energy systems at the same site. However, the environmental trade-offs associated with this strategy are still unclear. Therefore, this study aimed (i) to assess for the first time the environmental impacts of tissue paper produced at a typical industrial site in Portugal using slush and market pulp as the main raw material, and (ii) to assess the environmental effects of the integration of bioenergy produced in the pulp mill in tissue production. A life cycle assessment was conducted from cradle to gate using real data from the production of eucalyptus wood, eucalyptus pulp and tissue paper. The results showed that energy consumption in tissue paper production is the main hotspot for most impact categories. When bioenergy is used in tissue production, the environmental impacts decrease by up to 20% for categories other than marine eutrophication and mineral resource scarcity. These results are relevant to support decision making concerning sustainable practices not only for the pulp and paper industry but also for the authorities in charge of defining environmental policies, incentives and tax regulations.

Identifying macrofloating debris hotspots in the Mediterranean Sea applying multiplatform methodologies

The Mediterranean Sea is considered the world's sixth greatest hotspot for marine litter; however, quantifying the extent of marine debris in the oceans is a challenge, especially due to variations in survey methodologies. This study aims to assess the spatial abundance and distribution of macrofloating debris (> 2.5 cm) in the Mediterranean basin through visual surveys carried out by methods (research vessel, sailing vessel, and aerial) and approaches (science and citizen science). Aerial and research vessel surveys estimated litter at 1.88 ± 2.3 items·km−2 and 0.89 ± 1.61 items·km−2 respectively for the whole Mediterranean; moreover both methods agreed that the main macrofloating debris hotspots were in the east of Algeria, Tyrrhenian, Adriatic and Alboran Seas. Likewise, for the common blocks analysed aerial surveys estimated greater amounts of macrofloating debris than research vessels (mean 1.92 ± 2.61 items·km−2 vs. 0.94 ± 1.69 items·km−2) highlighting the different detection capacities of the two methods. In the Spanish Mediterranean continental shelf, results obtained from research vessels showed mean values of 8.6 ± 7.8 items·km−2 for 2021 and 3.86 ± 3.96 items·km−2 for 2022. Sailing vessels along the Spanish coastline registered up to 70.87 ± 257.23 items·km−2 in waters of the Cabrera Island, which is a Marine Protected Area. No significant differences between citizen science and scientific methods were found, which suggests that the implementation of this tool could be very useful in obtaining greater datasets. Results on the abundance of macrofloating debris could be attributed to various factors, including the influence of mighty rivers, a dense population in these areas, especially during some seasons like summer, and the effect of some currents and eddies, such as the Algerian and the northern currents, which also influence the transboundary plastics.

A bibliometric analysis of Oropouche virus.

Oropouche virus (OROV) causes systemic infections including the nervous and blood systems, posing a significant and growing public health challenge. However, a comprehensive review of the bibliometric analysis of OROV is still lacking. Therefore, the objective of this study was to provide insight into the research dynamics and current hotspots of OROV. This study used bibliometric analysis to explore the current status of research related to OROV. 148 publications from 1961 to 2024 were retrieved from the Scopus database. Countries, authors, institutions, journals, references, and keywords were visualized using VOSviewer, CiteSpace, R studio, and Bibliometrix. Microsoft Excel was used for statistical analysis. Brazil is the country with the highest number of publications, total cited frequency, and the most extensive international collaboration. The most popular journal in this field is the American Journal of Tropical Medicine and Hygiene. Instituto Evandro Chagas is the institution with the highest number of publications, and Eurico Arruda is involved in the highest number of publications. Keyword co-occurrence analysis showed that Oropouche bunyavirus, virology, bunyavirus, priority journal, and nucleotide sequence are the main research hotspots in this field. Our study provides a comprehensive overview of the research trends and key areas of focus in OROV. The field is currently experiencing rapid growth, as evidenced by the rising number of annual publications, which not only highlights increased research activity but also lays a solid foundation for further in-depth investigations. This trend offers valuable insights for developing effective strategies for outbreak prevention and control in public health. Presently, researchers are concentrating on the detailed study of Bunyavirus infections, employing both virological and genetic approaches to elucidate their complex pathogenic mechanisms.

BIOCLIMATIC MODELING OF THE SPECIES JURINEA SCHACHIMORDANICA (ASTERACEAE)

For more than 60 years, herbarium specimens of this species have not been recollected and targeted field studies have not been conducted. In 2023-2024, bioclimatic modeling was carried out on the basis of targeted field research in Shahimardan and the Kyrgyz Republic (Batkent; Okhna) region of the Fergana Valley. According to the RCP 2.6 (2061-2080) climate scenario, an increase in temperature of 0.4-1.6 °C will create many potentially suitable areas in the form of the regions of Kazakhstan and Tajikistan. It is directly related to precipitation (Bio19) and elevation (Elv.) in the coldest quarter. Under the RCP8.5_2070s climate scenario, an increase in temperature of 1.4-2.6 °C has replaced scattered high-level suitable areas with medium-level suitable areas. Under both climate scenarios, temperature increases of 0.4–1.6 °C and 1.4–2.6 °C did not adversely affect the species' main hotspots.

The effects of earthworm species on organic matter transformations and soil microbial communities are only partially related to their bioturbation activity

Earthworms are pivotal in shaping soil ecological processes through their bioturbation activity and organic matter consumption. Earthworm species are known to have different impacts on soil structure, but only a small number of species have been studied so far, and few studies have examined how earthworms simultaneously affect soil functions. Here, we measured the impact of different earthworm species on soil structure (bioturbation function), carbon (C) and nitrogen (N) dynamics and the microbial community (organic matter transformation function), while exploring the links between these functions, across distinct soil compartments (surface casts, below-ground drilosphere, and bulk soil). Six earthworm species (Lumbricus terrestris, Allolobophora chlorotica, Octolasion cyaneum, Octodrilus complanatus, Aporrectodea caliginosa meridionalis and Microscolex dubius) of different ecological categories and functional groups were incubated in soil cores with soil and alfalfa litter for 6 weeks. Our results on the bioturbation function illustrated a great diversity of behaviors and confirmed the relevance of a functional classification based on bioturbation metrics. The main microbial hotspots were surface casts, whose characteristics allowed to distinguish two groups of species. Octod. complanatus, L. terrestris and M. dubius induced high humidity (respectively, +57, +48, +74%), high C (respectively, 19.9, 24.8, 33.2 g kg⁻1 dry soil) and N (respectively, 2, 2.3, 3.2 g kg⁻1 dry soil) content and microbial community selection, promoting C and N mineralization. The three other species had a lower impact. The below-ground drilosphere only showed specific characteristics in the case of L. terrestris. The effects of the studied species on the organic matter transformation function did not align with their bioturbation activities nor with their ecological category. These findings show that the contribution of earthworms to C and N turnover is only partially dependent on their bioturbation effects and suggest the usefulness of developing distinct functional groups based on the specific soil functions under consideration.

The comparative techno-economic and life cycle assessment for multi-product biorefinery based on microwave and conventional hydrothermal biomass pretreatment

Microwave as an efficient and clean energy, is easy integrated with DES pretreatment and biorefinery process to achieve process intensification for cleaner production and sustainable development. However, there are worries about its economic and environmental feasibility for application in biorefinery plant. This work conducted the techno-economic (TEA) and life cycle assessment (LCA) of the entire biorefinery process based on DES pretreatment by microwave heating (MH) for producing glucose, furfural and lignin from lignocellulose, of which the results were compared with conventional heating (CH). For pretreating equivalent biomass, the total yield of products obtained from MH-assisted process was 8.53% higher than that of CH-assisted process due to microwave intensification effect. From the perspective of cradle-to-gate LCA, the MH-assisted process saved energy demand of 5.82%, reducing the environmental impacts global warming (GW) and fossil resource scarcity (FRS) by 4.85% and 5.69%, respectively, relative to CH-assisted process. The main environmental hotspots of both two processes concentrated on the raw material extraction (RME), followed by product separation and solvent recovery (PSSR) stages. Based on economic evaluation, the specific values of TAC regarding one-ton product for MH- and CH-assisted processes were 3194.35 and 3400.37 $/(y⋅t), respectively. Therefore, the MH-assisted pretreatment possessed certain environmental and economic advantages due to product increasement, energy consumption reduction in the DES pretreatment, and burden reduction for subsequent enzyme hydrolysis. Compared to the single-product biorefinery, the multi-product biorefinery strategy was more sustainable and could maximize the advantages of microwave intensification. However, some issues about the design of microwave reactors and temperature monitoring must be considered to pursue scale-up biorefinery plant.

Global hotspots and trends in Acanthosis nigricans research: A bibliometric and visualized analysis.

Acanthosis nigricans (AN) is a common skin disease characterized by clear pigmented patches on the folds of the skin. However, the AN research field lacks scientific and comprehensive bibliometric analysis. This article aims to use bibliometric methods to summarize and visualize the distribution patterns, research hotspots, and development trends of AN literature. Literature from 1900 to 2024 was retrieved from the Web of Science Core Collection database through AN's thematic search. Using CiteSpace, VOSviewer, and Excel 2019, conduct a comprehensive analysis of the number of publications, countries/regions, institutions, authors, journals, highly cited literature, keywords, and so on, and sort out the hotspots and directions of AN. From 1900 to 2024, 1675 publications were included in the bibliometric analysis, showing a steady annual increase in the number of publications. The United States leads in this research field, with the University of Texas System being a key research institution. The Journal of Clinical Endocrinology & Metabolism has the highest number of published papers. The most cited article is "Syndromes of Insulin Resistance and Acanthosis Nigricans: Insulin-Receptor Disorders in Man" (1976). The author Taylor, SI, has published the most papers. "Acanthosis nigricans" is the most frequently occurring keyword. The main research hotspots and frontier areas in AN research are as follows: (1) The relationship between AN and other diseases is a popular research topic; (2) The connection between AN and insulin resistance (IR) is a current research focus; (3) Treatment of AN, with an emphasis on addressing the underlying causes and improving local skin conditions, represents the cutting edge of this field. This study summarizes the research trends and hotspots in the field of AN, offering valuable information and insights for scholars focused on AN scientific research, and providing a reference for future research directions.

Lower Microscopy Sensitivity with Decreasing Malaria Prevalence in the Urban Amazon Region, Brazil, 2018-2021.

Malaria is increasingly diagnosed in urban centers across the Amazon Basin. In this study, we combined repeated prevalence surveys over a 4-year period of a household-based random sample of 2,774 persons with parasite genotyping to investigate the epidemiology of malaria in Mâncio Lima, the main urban transmission hotspot in Amazonian Brazil. We found that most malarial infections were asymptomatic and undetected by point-of-care microscopy. Our findings indicate that as malaria transmission decreases, the detection threshold of microscopy rises, resulting in more missed infections despite similar parasite densities estimated by molecular methods. We identified genetically highly diverse populations of Plasmodium vivax and P. falciparum in the region; occasional shared lineages between urban and rural residents suggest cross-boundary propagation. The prevalence of low-density and asymptomatic infections poses a significant challenge for routine surveillance and the effectiveness of malaria control and elimination strategies in urbanized areas with readily accessible laboratory facilities.

A bibliometric and visual analysis of the research status and hotspots of seborrheic dermatitis based on web of science.

Seborrheic dermatitis (SD) is a common chronic inflammatory skin disease. In recent years, significant progress has been made in the field of SD, but there has been no bibliometric research yet. This study aims to use bibliometric methods to analyze the current research status and hot topics of SD, to understand further the research trends and future development prospects in this field. Retrieve core literature on SD from the Web of Science database and conduct a detailed analysis using CiteSpace and VOSviewer software based on factors such as publication volume, countries (regions), research institutions, journals, authors, highly-cited papers, and keywords. From 1996 to 2024, a total of 1436 publications were included in the bibliometric analysis. The number of publications has shown an increasing trend year by year. The USA is the leading country in this field of research. The University of California System is the primary research institution. The International Journal of Dermatology is the journal with the highest number of publications. The author Yang Won Lee has the highest number of publications, while the article "Seborrheic Dermatitis" (2004) by Gupta, A.K. has been cited the most. "Seborrheic dermatitis" is the most frequently occurring keyword. The main research hotspots and frontiers in SD are as follows: (1) The relationship between SD and other skin diseases is a popular research topic; (2) Malassezia and inflammation are current research hotspots in SD; and (3) Focusing on antifungal and anti-inflammatory treatments for SD is the current frontier direction in this field. This study is a summary of the current status and hot trends of SD research, which helps clinical doctors and researchers quickly understand the insights and valuable information of SD research and provides reference for clinical decision-making and finding future research directions.

Insights into different marine aquaculture infrastructures from a life cycle perspective

Aquaculture facilities represent an often-neglected process in environmental impact studies. This study focus on the environmental impact assessment of alternative net materials in Mediterranean marine aquaculture. A Life Cycle Assessment was conducted using primary and secondary data from specific databases and literature. Three baseline scenarios were compared: copper alloy net cages with 100 % of recycled material (CAN100), 75 % of recycled material (CAN75), and polyethylene net (PEN) System boundaries include manufacturing and disposal of cages, nets, and mooring system. The use and emissions of antifouling paints and CAN were considered. Sensitivity analysis of the most impacting sub-processes and Uncertainty analysis were also conducted. The use of CAN is advantageous in terms of environmental impact, but only considering a complete recyclability of the net at the end of its service life. Moreover, when considering a reduced service life of the PEN due to the detrimental effect of biofouling, the advantage of the CAN is even more evident. To counteract the negative effect of biofouling, copper-based antifouling paints are generally used in marine aquaculture. These products are a main environmental hotspot in PEN systems. Therefore, a higher consumption of such products could determine an environmental burden shifting from CAN to PEN ones. So far, CAN are not widespread in the aquaculture industry, mainly due to the high cost of initial investment compared to traditional PEN. Considering operational and environmental advantages, CAN cages could represent an affordable and resilient solution for aquaculture enhancing environmental, economic, and social performances of this industry.

A cradle-to-customer life cycle assessment case study of UK vertical farming

Global population rise, increased rural to urban migration, climate change and conflict have placed strain on global trade and food supply chains. Vertical farming (VF) is a relatively novel method for cultivating many fresh fruits and vegetables, and often is claimed to have lower environmental impacts than field cultivation. However, to date there are few studies utilising primary data which have evaluated the environmental impact VF may have. This study utilised Life Cycle Assessment (LCA) to evaluate the environmental impact of lettuce production in a commercial vertical farm in the UK. This was compared with data from the literature on the impacts of lettuce in field cultivation. Scenarios were also examined to evaluate the impact of VF systems with varying electricity sources, and waste, water and nutrient management options. The VF was found to have a similar or lower Climate Change impact than field cultivation, depending on energy source used. VF had a slightly higher environmental impact than field cultivation in some other environmental impact categories such as freshwater eutrophication potential and acidification potential. Electricity demand and the medium used for ‘plugs’ in the VF were found to be the main hotspots of the system. The results of this study provide insights on the environmental impact and resource efficiency of VF, feasibility for larger scale deployment, and provide further empirical evidence to support the claims made previously in the literature.