Main Causes Of Infant Mortality Research Articles

Analysis of Adverse Drug Reactions (ADRs) Using Antibiotic for Community Acquired Penumonia (CAP) Disease of Toddler

Pneumonia is an infection that causes inflammation of the lung tissue so that the lung sacs are filled with infectious agents and are the main cause of infant mortality in the world. The initial therapy for pneumonia is the use of antibiotics. Irrational use of antibiotics can lead to ADRs. Adverse Drug Reactions (ADRs) often cause obstacles in the implementation of treatment. The purpose of this study was to see how ADRs influence the use of antibiotics on the clinical outcomes of pneumonia patients. The method analytic observational study using a cross-sectional design which is carried out prospectively, by collecting data on inpatients. Data were obtained from interviews with patients and/or patient families using the Naranjo questionnaire, as well as searches of patient medical records during the period January - March 2023. Analysis of ADRs on the use of antibiotics on outcomes was analyzed by the Likelihood ratio. This study was dominated by patients aged <2 years (61.5%) with improved outcomes (97.15%). The results obtained showed that there was no significant relationship between ADRs using antibiotics and patient outcomes with a p>0.05 (p=0.798). The conclusion of this study is that there is no effect of ADRs using antibiotics on patient outcomes.

P49: Are We Timely Detecting Congenital Heart Defects in Bogotá and Cali (Colombia)?

Background: Congenital heart defects (CHD) are the main cause of infant mortality. Properly attending CHD demands strategies to improve prenatal diagnosis, planning birth on adequate hospitals, assure timely clinical care for complex cases, and guarantee follow-up and health care access for patients lifelong. Accordingly, Colombian normativity dictates that all pregnant women must have at least a first and second trimester screening with fetal heart examination, 7 to 10 prenatal control visits, and psychological support and information on voluntary termination. The aim of this study was to characterize demographics and prenatal care of expectant mothers of pediatric patients with a confirmed CHD diagnosis. Methods: This study was prospective and observational with an incidental sampling of 134 CHD patients treated at Fundación Cardioinfantil (Bogotá), Hospital Universitario San Ignacio (Bogotá), and Clinica Imbanaco (Cali) in Colombia. Women, after consent, were interviewed about demographics, prenatal care, pre and postnatal diagnosis, and children clinical evolution. We analyzed CHD according to their complexity (simple, moderate or complex) and clinical presentation (isolated, multiple anomalies or syndromes). Data were collected using the REDCap tool, descriptive statistics were calculated using Excel. Variables were expressed as mean (range). Results: 43% of all CDH were prenatally detected (66% of complex CHD were only detected postnatally). Mothers were young (mean age 28.1 years, DE 6.2), 82.1% had completed high school, 71.6% had low-income and 82.1% lived in urban areas with the father. Only 3% had twin pregnancies and 19% had chronic comorbidities (hypertensive disorders, diabetes, or hypothyroidism). On average, mothers had 6.8 prenatal control visits (DE 2.6) and 4.6 ultrasound scans (DE 2.5). As for the proper moment for ultrasound scans, only 61.1% of first-trimester scans and 58.9% of second-trimester scans were on time according to normative. 41% of women did not have psychological support, and 49% did not receive information on voluntary termination. About labor, 45% were spontaneous and 55% cesarian deliveries. Regarding babies (50.7% females), 24.0% were small for gestational age and 25.4% were born before 37 weeks. Most babies had an isolated CHD (15% simple, 76% complex), 5% had multiple anomalies, and 5% syndromes. Comparing prenatal diagnosis (ultrasound scans) and postnatal diagnosis, only in 22% of cases we found a complete agreement, and in 56% CDH was not reported on the ultrasound exams. Conclusion: Ultrasonography is a useful tool to detect CHD, but improving early detection requires better and timely access, especially for complex cases. Colombian normative for prenatal care is not working as expected. Delfos program is funded by Minciencias (Contract No.120484267276).

A Review Article of Corticotrophin-Releasing Hormone and Preterm Birth: A Placental Clock

Preterm Birth is one of the main causes of infant mortality and morbidity worldwide. An estimated 15 million preterm births are birthed each year. Preterm Birth is not a single disease but a complex syndrome. The placenta's production of Corticotrophin-Releasing Hormone (CRH) is one theory for Preterm Birth. The peptide hormone CRH, which levels rise exponentially during pregnancy, has been linked to preterm Birth due to its endocrine, autocrine, and paracrine functions. It has been suggested that CRH functions as a component of the placental clock, with preterm Birth occurring when the placental clock is activated too early. In this review article, we will discuss Preterm Birth and the role of CRH in Preterm Birth. Keywords: Preterm Birth, Corticotrophin-Releasing Hormone (CRH), Placental clock

An overview of diarrhea among infants and under-five in Punjab-Pakistan

BackgroundDiarrhea, pneumonia, malnutrition, tuberculosis, measles, and fever are the leading causes of mortality in children under five-years of age (0–59 months), whereas diarrhea alone is the world's second-biggest cause of mortality in this population. This study is particularly important for Pakistan as it focuses on one of the main causes of infant mortality, diarrhea, which is a major challenge for Pakistan to achieve the Sustainable Development Goals to reduce infant mortality to 12/1000 live births by 2030. AimThis study was planned to investigate the various household, parental, environmental, and child-related factors causing diarrheal diseases in children aged 0–59 months in Punjab Pakistan. MethodsThe study used the data of 38,405 households from the Multiple Indicator Cluster Survey (MICS) 2017–18, directed by the Punjab Bureau of Statistics. Comprehensive descriptive statistics, i.e., cross-tabulations and logistic regression were used for the detailed analysis. FindingsThe results showed that infants are more probable to get diarrhea than older children. A wide range of influences were found to affect the probability of a child getting diarrhea, including child-specific, mother-specific and environment-specific ones. One prominent finding was that, at the mother level, the education of the mother played a significant role in reducing diarrhea among children under five-years of age (0–59 months). DiscussionThe results of the study contribute to the literature by highlighting that it is an interplay of factors that result in diarrhea. Hence, improving the source of drinking water, e.g., tap water and bottled water, can decrease the occurrence of diarrhea, especially in poor households. It was also revealed that households with a toilet facility of flush have less probability of their children being diagnosed with diarrhea than toilet facilities in open drains and fields. On the child level, results suggested that birth order matters as well, with the firstborn child having a lower probability of contracting diarrhea than siblings born after. Application to practiceInterventions targeting infants and mothers of infants aimed at reducing diarrhea are expected to be very effective to reduce child mortality, one of the main child health challenges faced by Pakistan.

The Effect of DEHY PRO (Dehydration Prevention) in Improving Preventive Behaviour among Parents toward Diarrhea Dehydration in Children Under Five

The main cause of infant mortality in diarrhea is dehydration. Children under five are often brought to health services in deteriorating conditions to severe dehydration. Children under five deaths due to diarrhea are likely to be prevented if parents are able to recognize the signs of dehydration in children and take appropriate initial treatment when children have diarrhea. This study aims to determine the effect of the Dehy Pro application improves parents' behavior in preventing diarrhea dehydration in children under five. This study is a pre-experimental study with a one-group pre-posttest design. The research begins with the development of the Dehy Pro application through 4 stages: Define, Design, Develop, and Disseminate. Dehy Pro was introduced and used by 50 mothers with children under five in Karangrejo Village, Sumbersari-Jember District selected by using a purposive sampling technique. The independent variable of this study was the Dehy Pro application, meanwhile, the dependent variable of the study was the preventive behavior of diarrhea dehydration was measured in the form of knowledge, attitudes, and prevention of diarrhea dehydration. The statistical test used is the Wilcoxon Sign Rank Test <0.05. Dehy Pro significantly affected maternal behavior by increasing knowledge (p<0.000), attitude (p>0.000), and prevention of diarrhea dehydration (p<0.000). Dehy Pro can be an effective health promotion effort in reducing the number of diarrhea dehydration in children under five through increasing knowledge and the role of parents to take steps to prevent dehydration due to diarrhea.

Temporal trends in prevalence and infant mortality of birth defects in Brazil, from 2001 to 2018

Congenital anomalies (CA) are a relevant problem for global public health, affecting about 3% to 6% of newborns worldwide. In Brazil, these are the second main cause of infant mortality. Thus, extensive studies are needed to demonstrate the impact of these anomalies on births and deaths. The present study describes the temporal trends of prevalence and infant mortality due to CA among live births in Brazil and regions, from 2001 to 2018, using the related data between the Live Birth Information System (SINASC, acronym in Portuguese) and the Mortality Information System (SIM, acronym in Portuguese). The prevalence and infant mortality due to CA has increased in Brazil and in most regions, especially in the Northeast and North. CAs in the musculoskeletal system were the most frequent at birth (29.8/10,000 live births), followed by those in the circulatory system (12.7/10,000 live births), which represented the primary cause of death in this group. The applied linkage technique made it possible to correct the national prevalence of CA by 17.9% during the analyzed period, after retrieving the anomalies reported in SIM, thereby proving to be a good tool to improve the quality of information on anomalies in Brazil.

Tendência temporal da prevalência e mortalidade infantil das anomalias congênitas no Brasil, de 2001 a 2018

Abstract Congenital anomalies (CA) are a relevant problem for global public health, affecting about 3% to 6% of newborns worldwide. In Brazil, these are the second main cause of infant mortality. Thus, extensive studies are needed to demonstrate the impact of these anomalies on births and deaths. The present study describes the temporal trends of prevalence and infant mortality due to CA among live births in Brazil and regions, from 2001 to 2018, using the related data between the Live Birth Information System (SINASC, acronym in Portuguese) and the Mortality Information System (SIM, acronym in Portuguese). The prevalence and infant mortality due to CA has increased in Brazil and in most regions, especially in the Northeast and North. CAs in the musculoskeletal system were the most frequent at birth (29.8/10,000 live births), followed by those in the circulatory system (12.7/10,000 live births), which represented the primary cause of death in this group. The applied linkage technique made it possible to correct the national prevalence of CA by 17.9% during the analyzed period, after retrieving the anomalies reported in SIM, thereby proving to be a good tool to improve the quality of information on anomalies in Brazil.

Air Pollution and Aeroallergens as Possible Triggers in Preterm Birth Delivery.

Preterm birth (PTB) identifies infants prematurely born <37 weeks/gestation and is one of the main causes of infant mortality. PTB has been linked to air pollution exposure, but its timing is still unclear and neglects the acute nature of delivery and its association with short-term effects. We analyzed 3 years of birth data (2015-2017) in Turin (Italy) and the relationships with proinflammatory chemicals (PM2.5, O3, and NO2) and biological (aeroallergens) pollutants on PTB vs. at-term birth, in the narrow window of a week before delivery. A tailored non-stationary Poisson model correcting for seasonality and possible confounding variables was applied. Relative risk associated with each pollutant was assessed at any time lag between 0 and 7 days prior to delivery. PTB risk was significantly associated with increased levels of both chemical (PM2.5, RR = 1.023 (1.003-1.043), O3, 1.025 (1.001-1.048)) and biological (aeroallergens, RR ~ 1.01 (1.0002-1.016)) pollutants in the week prior to delivery. None of these, except for NO2 (RR = 1.01 (1.002-1.021)), appeared to play any role on at-term delivery. Pollutant-induced acute inflammation eliciting delivery in at-risk pregnancies may represent the pathophysiological link between air pollution and PTB, as testified by the different effects played on PTB revealed. Further studies are needed to better elucidate a possible exposure threshold to prevent PTB.

The Factors Associated with the Incidence of Low Birth Weight LBW

Maternal and child health issues are still national priority in Indonesia. LBW cases are one of the major causes of infant mortality in Indonesia. Up to the policies to improve the health status of mothers and children have only focused on mothers and children, and rarely involved the participation of families. Low birth weight (LBW) the main cause of infant mortality before the age of one month (neonates). One of the causes LBW is anemia in pregnant women. The objective of this study is to reveal the relationship of anemia, preeclampsia and CED simultaneously with the incidence of LBW at Kayuagung Regional Public Hospital in Ogan Komering Ilir (OKI) Regency in 2021. This is an analytical survey study using cross sectional research. The population of this study was all mothers giving birth at Kayuagung Regional Public Hospital in 2021. 860 mothers in total, and the number of sample was 97 respondents. The sampling technique was systematic random sampling. The data analysis was chi square statistical test, p value ≤ α value (0,05). The result of this on 97 respondents revealed that there was a relationship between anemia and the incidence of LBW p value = 0,002, there was a relantionsjip betweenpreeclampsia and the incidence og LBW p value = 0,000, and there was a relantionship between CED and the incidence of LBW p value = 0,000. Based on the results of the study, it is expected that midwives improve health services to the community in order to reduce infant mortality.

Applying Formal Concept Analysis for the Recognition of Infant Mortality Patterns.

Infant mortality (IM), an index that corresponds to the number of deaths among children up to one year, is an important social indicator of a region. It generally reflects the conditions of socioeconomic development - in addition, the access and quality of resources available for maternal and child health care. Monitoring its magnitude, thus, can help in the definition of public policies for its confrontation. The main causes of IM can be also associated with biological, behavioral, and public health issues. In this work, implication and association rules based on Formal Concept Analysis are used to recognize patterns in births occurring in the state of Amapá (located in the Brazilian Amazon), where the index of infant mortality is more severe.

Current Trends in the Diagnosis, Screening and Treatment of Spinal Muscular Atrophy

Spinal muscular atrophy is one of the most severe hereditary neuromuscular diseases and one of the main causes of infant mortality caused by hereditary diseases. Being a monogenic disease, SMA is characterized by a wide range of phenotypes, which are based on the influence of genetic modifiers of the disease. These modifiers determine the development of a more severe or milder form of the disease and can act as potential targets of disease therapy. To date, there are three certified drugs for the treatment of SMA, the action of two of them is directed at the transcript of the main modifier of the disease the SMN2 gene. With the advent of effective therapy, the issue of screening newborns for the purpose of early detection of patients and the beginning of treatment of SMA at the presymptomatic phase to achieve maximum effectiveness of drugs becomes relevant. In addition to neonatal screening, population screening plays an important role, which may result in a decrease in the frequency of births of children with SMA.

Implementation of a Mobile Application based on the Convolutional Neural Network for the Diagnosis of Pneumonia

Pneumonia is the main cause of infant mortality in Peru, which has led to plansfig, such as vaccination campaigns, greater economic investment in health, and the strengthening of specialized medical personnel, however, mortality rates remain high. In this sense, the implementation of new computer technologies such as Deep Learning through the use of the artificial neural network is proposed. The objective of this project was to determine the influence of a mobile application based on a Convolutional Neural Network for the diagnosis of Pneumonia, the project consists of the analysis of images of Chest X-rays with Pneumonia and Normal by means of an application developed called “Diagnost”. The study was carried out considering a control group and a study group formed by 33 medical staff members who used the application. The analysis of the data obtained was made based on the study of 3 indicators, detection time, result in accuracy, and reduction of medical assistance. According to the results, it was concluded that the mobile application based on the convolutional neural network allows the early detection of Pneumonia and allows the reduction of medical assistance, however, it is still necessary to continue working on the accuracy of the diagnosis.

Implementation of Kangaroo Mother Care (KMC) for low birth weight babies (LBWBs) at Budi Kemuliaan Mother and Child Hospital: a qualitative study

Introduction: The infant mortality rate is one indicator of the public health quality in a country. One of the main causes of infant mortality is low birth weight babies (LBWBs). Kangaroo Mother Care (KMC) is a treatment method for LBWBs by making direct contact between the baby’s skin and the mother’s skin. Budi Kemuliaan Mother and Child Hospital already practicing KMC since 2010 and it has succeeded. The purpose of this study was to determine the implementation of KMC for LBW mothers at Budi Kemuliaan Mother and Child Hospital.
 Methods: This study was qualitative research with Rapid Assessment Procedures (RAP) design. This research was conducted on mothers who gave birth with LBWB (<2500 grams) from 9 to 18 December 2011, and practice KMC at Budi Kemuliaan Mother and Child Hospital, Jakarta.
 Result: The implementation of KMC for LBW mothers at Budi Kemuliaan Mother and Child Hospital was affected by seven factors. Those factors were; mothers and their husbands have sufficient knowledge of KMC from health workers explanation, good acceptance attitude, given accountable information sources of KMC, there is the presence of KMC policy that supporting KMC program, health workers support, husband support, and sufficient health education and counseling of KMC for mother and their husband before discharge.
 Conclusion: There are seven factors that determine the successful implementation of KMC for LBW mothers at Budi Kemuliaan Mother and Child Hospital, those are; sufficient knowledge of KMC, acceptance attitude of KMC, information sources of KMC, the presence of KMC policy, health workers support, husband support, and sufficient health education of KMC for mother before discharge. This study suggested the formation of a support group to build social support between LBW families.

Routing of pregnant women as one of the ways to reduce infant mortality

One of the most important tasks that healthcare providers face is to reduce infant mortality. The purpose of our study was to assess the effects of routing of pregnant women with preterm birth on the infant mortality rate. Materials and methods: оperating data of the Federal State Statistics Service (Rosstat), operational notifications about death of young children under the age of 1, monthly reports of obstetric hospitals subordinate to Moscow Healthcare Department, annual reports of hospital departments providing neonatal care in medical organizations of Moscow Healthcare Department, and statistical data analysis. Results and discussion. The infant mortality rate in Moscow has been declining in recent decades and has been less than 6‰ annually since 2016. The share of newborns with extremely low birth weight is insignificant in overall rate. At the same time, extremely low birth weight is one of the main causes of infant mortality. As this category of newborns requires specific care, it is better to deliver such babies in perinatal centers that provide high quality medical care. Within 5 years, the share of children with ELBW born in perinatal centers and specialized obstetric hospitals has almost doubled. At the same time, there is an increase in the survival rate of children with extremely low birth weight by the age of one year in obstetric hospitals. Conclusion. Well-planned routing of patient within the large system of obstetric hospitals in Moscow could reduce death rate, increase the survival rate of children with extremely low birth weight and contribute to reducing infant mortality in the region.

Socioeconomic Determinants of Infant Mortality Rate in Asean: A Panel Data Analysis

The infant mortality rate indicates the health status of a country. Previous studies have proven that socioeconomic factors have a significant influence on infant mortality rates in both developed and developing countries. Further studies on infant mortality rates are useful for public service strategic policy in the health sector. The main purpose of this study was to analyze the socioeconomic factors influencing infant mortality rates in ASEAN based on panel data estimates for 2000-2017. The dependent variable for this study was infant mortality rate, while the independent variables were health expenditure, female labor force, maternal fertility rate, and GDP per capita. The authors concluded that the main cause of infant mortality in ASEAN is care during delivery. Other influencing factors include family health status, maternal education level, and socio-economic inequality. This study found that the size of the female workforce has a strong influence on increasing the infant mortality rate in ASEAN. The fertility rate also had a strong influence on increasing infant mortality rate in ASEAN, while GDP per capita had a negative influence on infant mortality rate. Health expenditure is proven to have no effect on the increase of infant mortality rates in ASEAN.

The features of the course of rotavirus infection in children and adults

Rotavirus infection, which is also known as "intestinal flu", belongs to the group of diseases caused by RNA genomic viruses of the Reoviridae family. In terms of prevalence, it ranks second after influenza; the mechanism of transmission is fecal-oral. Once in the body, within several hours the virus leads to damage to the mucous membrane of the gastrointestinal tract, which is clinically manifested in the form of gastroenteritis. Most often, children under the age of five get sick; after recovery, a fairly stable immunity remains. Due to its high contagiousness, the virus frequently causes outbreaks in organized children's groups. The main danger of rotavirus infection is a rather rapid dehydration of the body, therefore, any case of the disease should be under the supervision of a doctor, especially for children under the age of one year. Vaccination is one of the ways to prevent the development of the disease; for this purpose, both monovalent and polyvalent vaccines can be used. In developing countries, rotavirus infection is one of the main causes of infant mortality from infectious diseases. Adult patients are characterized by a subtle course of the disease, which can manifest itself in the form of a single vomiting and diarrhea, a slight increase in temperature. Meanwhile, it should be remembered that even with this course, the patient is an epidemic danger to others.

Mir200a and miR4695-5p profiling as potential biomarkers for preterm birth

BackgroundPreterm labor is one of the main health problems and after birth congenital anomalies, the main cause of infant mortality. Epigenetic dysregulation and miRNA modulation have been indicated in preterm birth. Therefore, this study aimed to evaluate the miR200a and miR4695-5p profiling as potential biomarkers for preterm birth. Materials and methodsSerum samples were collected from a total of 90 patients (49 women with preterm labor and 41 women with term labor). After miRNA extraction, expression levels of miR200a and miR4695-5p were evaluated using RT-PCR. ResultsAccording to the results, the expression levels of miR200a and miR4695-5p were significantly different between the two groups (p-value = 0.015 and p-value = 0.031, respectively). Moreover, the expression of miR4695-5p was positively correlated with the expression of miR200a. However, considering the sex of the fetus, no significant difference was observed in the expression levels of miR200a and miR4695-5p in women with preterm or term labor carrying a female infant (p-value = 0.925). AUC-ROC analysis showed an acceptable sensitivity (60%) and specificity (75%) of miR4695-5p as a biomarker for preterm birth outcome (p-value = 0.031), suggesting this gene as a suitable biomarker for preterm birth. On the other hand, according to the sensitivity (73%) and specificity (51%) according to the AUC-ROC analysis for miR200a (p-value = 0.232) further studies are required to assure the efficacy of this microRNA as a biomarker of preterm birth. ConclusionIn overall, these microRNAs may be used as effective biomarkers for identifying women at risk of preterm labor for taking suitable preventive or treatment measures.

Основные показатели в оценке состояния здоровья детей первого года жизни в Красноярском крае

The aim of the research is to analyze indicators and structure of infant mortality in Krasnoyarsk Territory for the period from 2014 to 2018. Material and methods. Th e article studies indicators of population mortality and fertility, infant mortality in Krasnoyarsk Territory for fi ve-year period from 2014 to 2018. Th e analysis of the results obtained is carried out in comparison with other constituent entities of the Russian Federation and with the country in general. Newborns morbidity rates in Krasnoyarsk Territory over a five-year period were studied in comparison with the data for the Russian Federation during 2017 and 2018. Results. The study revealed the excess of mortality over births in the region by 2018, with the coeffi cient 0.7 for 1000 population. It was found that in the period from 2014 to 2018 there is a decrease in infant mortality rate in the Russian Federation by 31.1 %; by 21.8 % in the Siberian Federal District; by 33.7 % (from 8.8 to 5.5 for 1000 alive births) in Krasnoyarsk Territory. The main causes of infant mortality in the territory are: conditions occurring in perinatal period, external causes and congenital anomalies (malformations). Decrease of infant mortality in the territory is primarily determined by the decrease in the number of deaths among children under 1 year of age due to the above-mentioned causes. Despite the annual decrease in infant mortality rate, on average, every third death occurs in the first 28 days of a child’s life. When studying the morbidity of newborns, one can mark a steady decline of the indicator both in the Russian Federation and in Krasnoyarsk Territory. At the same time, every year more than 80 % of absolute number of sick newborns falls on full-term babies. Conclusion. Th e results obtained during the study indicate a decrease in infant mortality rate over the study period. Th e study of indicators of infant mortality and morbidity in newborn children is fundamental in the fi eld of maternal and child health. Pediatricians need to pay special attention when examining newborns and children of the first year of life; they should timely identify pathological conditions and diseases, which will help reduce the risk of complications, chronic diseases, and, deaths.

ANALISIS FAKTOR RESIKO PAPARAN PESTISIDA PADA KEHAMILAN DENGAN KEJADIAN BERAT BADAN LAHIR RENDAH (BBLR) DI KOTA PADANGSIDIMPUAN TAHUN 2019

Low birth weight (LBW) is one of the main causes of infant mortality. The problem that arises is whether there is a relationship between risk factors for pesticide exposure during pregnancy and the incidence of LBW in agricultural areas. The purpose of this study was to determine the risk factors for pesticide exposure associated with LBW incidence. This research is a case control study. Subjects were divided into two groups: a case group of 25 farmers with a history of giving birth to LBW and a control group who were neighbors of case subjects without a history of giving birth to LBW, a total of 25 farmers. This research data collection using interviews and observations. Data analysis used univariate and bivariate analysis (chi square and fisher as alternatives). Research results: risk factors for exposure to pesticides that have been shown to be associated with the incidence of LBW in Padangsidimpuan, include: occupation of pregnant women related to pesticides (OR = 6,769) completeness of personal protective equipment (PPE) while doing activities in the fields (OR = 18,857) and storage pesticides (OR = 12,667). The recommended advice is to avoid work that is directly related to pesticides during pregnancy, if you have to participate in agricultural activities, pregnant women should use complete PPE.

Determining of Risk Factors of Low-Birthweight Babies in Padang, West Sumatra Using Logistic Regression Analysis

Infant mortality is one of the indicators used to measure the quality of life of a nation. The World Health Organization (WHO) stated that one of the main causes of infant mortality is the low birth weight (LBW). Efforts to reduce the incidence of LBW can be done by monitoring risk factors that influence the occurrence of LBW in the prenatal phase. This study aims to identify factors that significantly influence the incidence of LBW babies in Padang, West Sumatra, Indonesia. The analysis was carried out by using Logistic Regression Analysis on the data of maternal births domiciled in Padang, West Sumatra, Indonesia. It was concluded that variables that significantly affect the incidence of LBW are maternal weight, parity, distance from a previous birth, problems during pregnancy, and babies’ gender.