Magnitude Of Peak Velocity Research Articles

Subcooled flow boiling characteristics and CHF in an eccentric annulus at low pressure conditions

Controlled flow boiling conditions enhance the heat transfer rate in various industrial applications such as heat exchangers, fuel rod bundles etc. In nuclear industry, the presence of mixing vanes, spacers, channel creep deformation etc., may lead to the formation of narrow and wide zones around the fuel rods. The asymmetry in the cross-sectional flow area around the fuel rod can be modelled as eccentricity which may cause an irregular coolant flow distribution affecting the heat transfer rate. In the present study, the eccentricity (e) is defined as the ratio of offset (s) to the difference in radii of inner and outer cylinders (Ro−Ri). The current study introduces a framework that involves calibrating the departure size of vapour bubble (D) in the EMF model framework which enables the accurate prediction of subcooled flow boiling characteristics and CHF power in an annulus (0.0≤e≤0.50) at low operating pressure conditions. The developed framework is validated with experimental data and a very good match is noticed. It is observed that eccentricity causes a decrease in coolant peak velocity magnitude by 12.8% in the narrow zone for e=0.50. In the subcooled region, the accumulation of vapour bubbles impedes further heat transfer to the liquid coolant, and thus the peak heated wall temperature (≈380.88K) is observed in the narrow zone for e=0.50. Eccentricity causes early coolant phase change which in turn results in early occurrence of CHF (q=522KWm−2) in the narrow zone of e=0.50. A quadratic relationship is also established to predict the CHF power in terms of eccentricity (e) within 5% variation.

ANALYSIS OF AUGMENTATION IN PERFORMANCE OF PV MODULE INTEGRATED WITH FINNED PCM BY THREE-DIMENSIONAL TRANSIENT NUMERICAL SIMULATION

The overall performance of PV-PCM integrated with rectangular straight fins is analysed by three-dimensional transient numerical simulations. The influence of fin lengths, number of fins (n), and inclination (θ) of the system is investigated and compared with the PV-only system, and an optimal system configuration is then identified. Finite element analysis is used to conduct the simulations using COMSOL Multiphysics 6.0. The PV front surface is subjected to a constant flux of 1000 W/m2 for 180 min, and the PCM employed is RT25HC. The results indicate that the average PV temperature tends to drop with increasing inclination and fin length, thereby enhancing the PV efficiency, with maximum improvement attained for the full fin case for a given inclination and number of fins. Compared to the PV-only system, the highest PV temperature reduction and PV efficiency enhancement are 59.65 °C and 45.1%, respectively, for the horizontal system of full-length fins with a number of fins equal to 6. The full-fin PV-PCM system with 6 fins and 45° inclination gives the highest instantaneous power output of 14.16 W. The melting rate of PCM is strongly related to the heat transfer rate inside PCM, and the lowest melting time is obtained for the 8-finned PV-PCM system with θ = 45°. The peak velocity magnitude for all systems with different fin lengths is also examined to analyse the extent of convection levels within PCM.

Four-dimensional flow MR imaging for evaluating treatment response after transcatheter arterial chemoembolization in cirrhotic patients with hepatocellular carcinoma.

To prospectively evaluate the potential of four-dimensional (4D) flow magnetic resonance imaging (MRI) in predicting treatment responses after transcatheter arterial chemoembolization (TACE) in cirrhoticpatients with hepatocellular carcinoma (HCC). A total of 195 patients were classified into four groups (A-D): A, cirrhotic patients without HCC (n = 30); B, cirrhotic patients with HCC before TACE (n = 75); C, cirrhotic patients with HCC showing an incomplete response following TACE (n = 56); and D, cirrhotic patients with HCC achieving a complete response (CR) following TACE (n = 34). The patients were subjected to routine laboratory tests and 4D flow MRI using a 3-T MRI system to measure the quantitative parameters of blood flow in the portal vein (PV), splenic vein(SV), and superior mesenteric vein. The data collected by 4D flow MRI were compared among the groups using one-way analysis of variance. A multivariate analysis was performed to verify the association of clinical characteristics and 4D flow parameters with CR after TACE treatment. The average through-plane velocity, peak velocity magnitude, average net flow, peak flow, and net forward volume in the PV and SVwere significantly lower in groups B and C (P < 0.05) compared to those in group A. Moreover, average through-plane velocity and peak velocity magnitude in the PV in groups B and C were significantlylower than those in group D (P < 0.05). The multivariate analysis demonstrated that the average through-plane velocity and peak velocity magnitudein the PV were independently associated with CR in HCC patients after TACE (P < 0.05). The quantitative flow data obtained by 4D flow MRI may be useful for predicting CR after TACE in cirrhotic patients with HCC.

Marangoni convection in shallow annular pools of silicone oil heated from above

A numerical study in a two-dimensional, axisymmetric cylindrical geometry is performed to evaluate the effect of Marangoni convection in shallow liquid layers of silicone oil. The study aims to understand Marangoni convection for a range of temperature gradients (9.0 K, 11.5 K, and 14.0 K), layer depths (4.0 mm, 4.5 mm, and 5.0 mm) under earth gravity (1.0 g), and microgravity (0.5 × 10 −3 g) conditions. The finite element method is used to solve the present problem using COMSOL V5.6 commercial tool. The microgravity studies ensure Marangoni convection dominates natural convection. In the present simulation, it is found that Marangoni convection is influenced more by temperature difference than layer depths as the change in temperature gradient gives a higher velocity deviation than a change in layer depths. In the presence of fluid meniscus, the thermo-capillary force is observed to be less significant in driving the flow as the peak velocity magnitude is observed to get reduced by 60%. From the microgravity study, it is clear that for velocity magnitude at z = 2.5 mm the Marangoni convection contributes to almost 90% of the total convection.

Sequential aiming in pairs: the multiple levels of joint action

The task constraints imposed upon a co-actor can often influence our own actions. Likewise, the observation of somebody else’s movements can involuntarily contaminate the execution of our own movements. These joint action outcomes have rarely been considered in unison. The aim of the present study was to simultaneously examine the underlying processes contributing to joint action. We had pairs of participants work together to execute sequential aiming movements between two targets—the first person’s movement was contingent upon the anticipation of the second person’s movement (leader), while the second person’s movement was contingent upon the direct observation of the first person’s movement (follower). Participants executed separate blocks of two-target aiming movements under different contexts; that is, solely on their own using one (2T1L) and two (2T2L) of their upper limbs, or with another person (2T2P). The first movement segment generally indicated a more abrupt approach (shorter time after peak velocity, greater displacement and magnitude of peak velocity), which surprisingly coincided with lower spatial variability, for the 2T2P context. Meanwhile, the second segment indicated a similar kinematic profile as the first segment for the 2T2P context. The first movement of the leader appeared to accommodate the follower for their movement, while the second movement of the follower was primed by the observation of the leader’s movement. These findings collectively advocate two distinct levels of joint action including the anticipation (top–down) and mapping (bottom–up) of other people’s actions.

Influence of portal vein occlusion on portal flow and liver elasticity in an animal model.

Hepatic fibrosis causes an increase in liver stiffness, a parameter measured by elastography and widely used as a diagnosis method. The concomitant presence of portal vein thrombosis (PVT) implies a change in hepatic portal inflow that could also affect liver elasticity. The main objective of this study is to determine the extent to which the presence of portal occlusion can affect the mechanical properties of the liver and potentially lead to misdiagnosis of fibrosis and hepatic cirrhosis by elastography. Portal vein occlusion was generated by insertion and inflation of a balloon catheter in the portal vein of four swines. The portal flow parameters peak flow (PF) and peak velocity magnitude (PVM) and liver mechanical properties (shear modulus) were then investigated using 4D-flow MRI and MR elastography, respectively, for progressive obstructions of the portal vein. Experimental results indicate that the reduction of the intrahepatic venous blood flow (PF/PVM decreases of 29.3%/8.5%, 51.0%/32.3% and 83.3%/53.6%, respectively) measured with 50%, 80% and 100% obstruction of the portal vein section results in a decrease of liver stiffness by 0.8% ± 0.1%, 7.7% ± 0.4% and 12.3% ± 0.9%, respectively. While this vascular mechanism does not have sufficient influence on the elasticity of the liver to modify the diagnosis of severe fibrosis or cirrhosis (F4 METAVIR grade), it may be sufficient to attenuate the increase in stiffness due to moderate fibrosis (F2-F3 METAVIR grades) and consequently lead to false-negative diagnoses with elastography in the presence of PVT.

Intertidal Creeks and Overmarsh Circulation in a Small Salt Marsh Basin

AbstractThe role of intertidal creek networks in overmarsh circulation is not well constrained. In this study, we systematically remove intertidal creeks from a high‐resolution salt marsh digital elevation model and conduct new flow simulations with each iteration. Overall, removal of first‐ and second‐order creeks reduced drainage density by 65%, and this had a negligible effect on overmarsh circulation and tracer distribution. However, upon removal of third‐ and fourth‐order creeks, drainage density was reduced by 80% of the original value, and changes in peak velocity magnitude across various spatial and temporal scales reveal a system‐wide switch from ebb to flood dominance. This response coincides with the interruption of topographically connected creeks that facilitate the direct exchange of water and tracer between the marsh interior and the larger subtidal system. Further, this reduction in hydraulic connectivity gives rise to less expansive tracer dispersal and a systematic decline in tracer residence time. Together, these results reveal that for the Groves Creek marsh, lower‐order intertidal creeks have a minor role in overmarsh circulation, while higher‐order creeks increase the potential for short circuiting of flow; they greatly influence overall flood and ebb dominance, and net tracer dispersal and associated retention time. Results reported here provide new insight on, for example, salt marsh restoration and the requisite digital elevation model bathymetry for robust simulations of overmarsh circulation.

Inter-Laboratory Characterization of the Velocity Field in the FDA Blood Pump Model Using Particle Image Velocimetry (PIV).

A credible computational fluid dynamics (CFD) model can play a meaningful role in evaluating the safety and performance of medical devices. A key step towards establishing model credibility is to first validate CFD models with benchmark experimental datasets to minimize model-form errors before applying the credibility assessment process to more complex medical devices. However, validation studies to establish benchmark datasets can be cost prohibitive and difficult to perform. The goal of this initiative sponsored by the U.S. Food and Drug Administration is to generate validation data for a simplified centrifugal pump that mimics blood flow characteristics commonly observed in ventricular assist devices. The centrifugal blood pump model was made from clear acrylic and included an impeller, with four equally spaced, straight blades, supported by mechanical bearings. Particle Image Velocimetry (PIV) measurements were performed at several locations throughout the pump by three independent laboratories. A standard protocol was developed for the experiments to ensure that the flow conditions were comparable and to minimize systematic errors during PIV image acquisition and processing. Velocity fields were extracted at the pump entrance, blade passage area, back gap region, and at the outlet diffuser regions. A Newtonian blood analog fluid composed of sodium iodide, glycerin, and water was used as the working fluid. Velocity measurements were made for six different pump flow conditions, with the blood-equivalent flow rate ranging between 2.5 and 7 L/min for pump speeds of 2500 and 3500rpm. Mean intra- and inter-laboratory variabilities in velocity were ~ 10% at the majority of the measurement locations inside the pump. However, the inter-laboratory variability increased to more than ~ 30% in the exit diffuser region. The variability between the three laboratories for the peak velocity magnitude in the diffuser region ranged from 5 to 25%. The bulk velocity field near the impeller changed proportionally with the rotational speed but was relatively unaffected by the pump flow rate. In contrast, flow in the exit diffuser region was sensitive to both the flow rate and the rotational speed. Specifically, at 3500rpm, the exit jet tilted toward the inner wall of the diffuser at a flow rate of 2.5 L/min, but the jet tilted towards the outer wall when the flow rate was 7 L/min. Inter-laboratory experimental mean velocity data (and the corresponding variance) were obtained for the FDA pump model and are available for download at https://nciphub.org/wiki/FDA_CFD . Experimental datasets from the inter-laboratory characterization of benchmark flow models, including the blood pump model presented herein and our previous nozzle model, can be used for validating future CFD studies and to collaboratively develop guidelines on best practices for verification, validation, uncertainty quantification, and credibility assessment of CFD simulations in the evaluation of medical devices (e.g. ASME V&V 40 standards working group).

Quantitative Study of Abdominal Blood Flow Patterns in Patients with Aortic Dissection by 4-Dimensional Flow MRI

The purpose of this study is to evaluate the hemodynamic characteristics of the true lumen (TL) and the false lumen (FL) in 16 patients with aortic dissection (AD) using 4D flow magnetic resonance imaging (MRI) and thoracic and abdominal computed tomography (CT) angiography. The quantitative parameters that were measured in the TL and FL included velocity and flow. The mean area and regurgitant fraction of the TL were significantly lesser at all four levels (p < 0.05); the average through-plane velocity, peak velocity magnitude, average net flow, peak flow, and net forward volume in the TL were considerably higher (p < 0.05). The intimal entry’s size was negatively correlated with the blood flow velocity and flow rate in the TL (p < 0.05) and positively correlated with the average through-plane velocity, average net flow, and peak flow in the FL (p < 0.05); the blood flow indices in the TL were enhanced with an increase in the intimal entry numbers (p < 0.05) and the peak flow in the FL was lowered (p = 0.025); if FL thrombosis existed, the average through-plane velocity and peak velocity magnitude in the TL were substantially higher (p < 0.05). 4D flow MRI facilitates qualitative and quantitative analysis of the alterations in the abdominal aortic blood flow patterns.

Temporal-spatial reach parameters derived from inertial sensors correlate to neurodevelopment in toddlers born preterm

Temporal-spatial reach parameters are revealing of upper-limb function in children with motor impairments, but have not been quantified in a toddler population. This work quantitatively characterizes temporal-spatial reach in typically-developing (TD) and very-low-birth-weight (VLBW) preterm toddlers, who are at increased risk of motor impairment. 47 children born VLBW (<1500 g birth-weight; ≤32 weeks gestation) and 22 TD children completed a reaching assessment at 18–22 months of age, adjusted for prematurity. Inertial sensors containing accelerometers, gyroscopes and magnetometers were fixed to toddlers’ wrists while they reached for a cube. Reach time, path length, velocity at contact, peak velocity magnitude and timing, acceleration at contact, and peak acceleration were derived from inertial-sensor and high-speed video data. Preterm children also received the Bayley Scales of Infant Development—3rd Edition (BSID-III). Compared to TD toddlers, preterm toddlers had significantly different reach path length, velocity at contact, peak velocity magnitude and timing, acceleration at contact, and peak acceleration. Among preterm toddlers, decreased reach time (rho = −.346, p = .018), decreased time to peak velocity (r = −.390, p = .007), and increased peak acceleration (r = .298, p = .044) correlated to higher BSID-III fine motor scores. Toddlers with below-average fine motor scores had significantly higher peak and contact velocity. Preterm toddlers demonstrated substantial differences in temporal-spatial reach parameters compared to TD toddlers, and evidence indicated several reach parameters were revealing of function and may be useful as a clinical assessment.

Association Between Linear Growth and Bone Accrual in a Diverse Cohort of Children and Adolescents

Prevention of osteoporosis in adulthood begins with optimizing bone health in early life. The longitudinal association between growth and bone accretion during childhood is not fully understood. To assess the acquisition of whole-body (WB) and skeletal site-specific bone mineral content (BMC) relative to linear growth in a healthy, diverse, longitudinal cohort of children, adolescents, and young adults and to test for differences related to sex and African American race. This investigation was a mixed longitudinal study with annual assessments for up to 7 years at 5 US clinical centers. Participants were healthy children, adolescents, and young adults. The study dates were July 2002 through March 2010. The dates of the analysis were June through December 2016. Anthropometrics, BMC, and body composition via dual-energy x-ray absorptiometry. The superimposition by translation and rotation (SITAR) analysis method was used to define the mean trajectories for height, WB lean soft tissue, appendicular lean soft tissue, and WB and skeletal site-specific BMC acquisition and to measure the age and magnitude of peak velocity for each parameter. The SITAR modeling was performed separately by sex and self-reported race. Among 2014 healthy children, adolescents, and young adults (1022 [50.7%] female and 479 [23.8%] African American) aged 5 to 19 years at study entry, the mean age of peak height velocity was 13.1 years (95% CI, 13.0-13.2 years) in African American boys vs 13.4 years (95% CI, 13.3-13.4 years) in non-African American boys (difference, -0.3 years; 95% CI, -0.4 to -0.1 years) and 11.0 years (95% CI, 10.8-11.1 years) in African American girls vs 11.6 years (95% CI, 11.5-11.6 years) in non-African American girls (difference, -0.6 years; 95% CI, -0.7 to -0.5 years). Age of peak acquisition of WB BMC was 14.0 years (95% CI, 13.8-14.1 years) in African American boys vs 14.0 years (95% CI, 13.9-14.1 years) in non-African American boys (difference, -0.0 years; 95% CI, -0.2 to 0.2 years) and 12.1 years (95% CI, 12.0-12.3 years) in African American girls vs 12.4 years (95% CI, 12.3-12.5 years) in non-African American girls (difference, -0.3 years; 95% CI, -0.4 to -0.1 years). At age 7 years, children had acquired 69.5% to 74.5% of maximal observed height but only 29.6% to 38.1% of maximal observed WB BMC. Adolescents gained 32.7% to 35.8% of maximal observed WB BMC during the 2 years before and 2 years after peak height velocity. Another 6.9% to 10.7% of maximal observed WB BMC occurred after linear growth had ceased. In the group at highest risk for fracture, non-African American boys, peak fracture incidence occurred approximately 1 year before peak height velocity. In this longitudinal study, height gains substantially outpaced gains in BMC during childhood, which could contribute to fracture risk. A significant proportion of bone is accrued after adult height is achieved. Therefore, late adolescence represents a potentially underrecognized window of opportunity to optimize bone mass.

Temporal–spatial reach parameters derived from inertial sensors: Comparison to 3D marker-based motion capture

Reaching is a well-practiced functional task crucial to daily living activities, and temporal–spatial measures of reaching reflect function for both adult and pediatric populations with upper-extremity motor impairments. Inertial sensors offer a mobile and inexpensive tool for clinical assessment of movement. This research outlines a method for measuring temporal–spatial reach parameters using inertial sensors, and validates these measures with traditional marker-based motion capture. 140 reaches from 10 adults, and 30 reaches from nine children aged 18–20 months, were recorded and analyzed using both inertial-sensor and motion-capture methods. Inertial sensors contained three-axis accelerometers, gyroscopes, and magnetometers. Gravitational offset of accelerometer data was measured when the sensor was at rest, and removed using sensor orientation measured at rest and throughout the reach. Velocity was calculated by numeric integration of acceleration, using a null-velocity assumption at reach start. Sensor drift was neglected given the 1–2s required for a reach. Temporal–spatial reach parameters were calculated independently for each data acquisition method. Reach path length and distance, peak velocity magnitude and timing, and acceleration at contact demonstrated consistent agreement between sensor- and motion-capture-based methods, for both adult and toddler reaches, as evaluated by intraclass correlation coefficients from 0.61 to 1.00. Taken together with actual difference between method measures, results indicate that these functional reach parameters may be reliably measured with inertial sensors.

Brain strain uncertainty due to shape variation in and simplification of head angular velocity profiles.

Head angular velocity, instead of acceleration, is more predictive of brain strains. Surprisingly, no study exists that investigates how shape variation in angular velocity profiles affects brain strains, beyond characteristics such as peak magnitude and impulse duration. In this study, we evaluated brain strain uncertainty due to variation in angular velocity profiles and further compared with that resulting from simplifying the profiles into idealized shapes. To do so, we used reconstructed head impacts from American National Football League for shape extraction and simulated head uniaxial coronal rotations from onset to full stop. The velocity profiles were scaled to maintain an identical peak velocity magnitude and duration in order to isolate the shape for investigation. Element-wise peak maximum principal strains from 44 selected impacts were obtained. We found that the shape of angular velocity profile could significantly affect brain strain magnitude (e.g., percentage difference of 4.29-17.89% in the whole brain relative to the group average, with cumulative strain damage measure (CSDM) uncertainty range of 23.9%) but not pattern (correlation coefficient of 0.94-0.99). Strain differences resulting from simplifying angular velocity profiles into idealized shapes were largely within the range due to shape variation, in both percentage difference and CSDM (signed difference of 3.91% on average, with a typical range of 0-6%). These findings provide important insight into the uncertainty or confidence in the performance of kinematics-based injury metrics. More importantly, they suggest the feasibility to simplify head angular velocity profiles into idealized shapes, at least within the confinements of the profiles evaluated, to enable real-time strain estimation via pre-computation in the future.

A transverse oscillation approach for estimation of three-dimensional velocity vectors, part I: concept and simulation study.

A method for 3-D velocity vector estimation using transverse oscillations is presented. The method employs a 2-D transducer and decouples the velocity estimation into three orthogonal components, which are estimated simultaneously and from the same data. The validity of the method is investigated by conducting simulations emulating a 32 × 32 matrix transducer. The results are evaluated using two performance metrics related to precision and accuracy. The study includes several parameters including 49 flow directions, the SNR, steering angle, and apodization types. The 49 flow directions cover the positive octant of the unit sphere. In terms of accuracy, the median bias is -2%. The precision of v(x) and v(y) depends on the flow angle ß and ranges from 5% to 31% relative to the peak velocity magnitude of 1 m/s. For comparison, the range is 0.4 to 2% for v(z). The parameter study also reveals, that the velocity estimation breaks down with an SNR between -6 and -3 dB. In terms of computational load, the estimation of the three velocity components requires 0.75 billion floating point operations per second (0.75 Gflops) for a realistic setup. This is well within the capability of modern scanners.

Phased-array vector velocity estimation using transverse oscillations

A method for estimating the 2-D vector velocity of blood using a phased-array transducer is presented. The approach is based on the transverse oscillation (TO) method. The purposes of this work are to expand the TO method to a phased-array geometry and to broaden the potential clinical applicability of the method. A phased-array transducer has a smaller footprint and a larger field of view than a linear array, and is therefore more suited for, e.g., cardiac imaging. The method relies on suitable TO fields, and a beamforming strategy employing diverging TO beams is proposed. The implementation of the TO method using a phased-array transducer for vector velocity estimation is evaluated through simulation and flow-rig measurements are acquired using an experimental scanner. The vast number of calculations needed to perform flow simulations makes the optimization of the TO fields a cumbersome process. Therefore, three performance metrics are proposed. They are calculated based on the complex TO spectrum of the combined TO fields. It is hypothesized that the performance metrics are related to the performance of the velocity estimates. The simulations show that the squared correlation values range from 0.79 to 0.92, indicating a correlation between the performance metrics of the TO spectrum and the velocity estimates. Because these performance metrics are much more readily computed, the TO fields can be optimized faster for improved velocity estimation of both simulations and measurements. For simulations of a parabolic flow at a depth of 10 cm, a relative (to the peak velocity) bias and standard deviation of 4% and 8%, respectively, are obtained. Overall, the simulations show that the TO method implemented on a phased-array transducer is robust with relative standard deviations around 10% in most cases. The flow-rig measurements show similar results. At a depth of 9.5 cm using 32 emissions per estimate, the relative standard deviation is 9% and the relative bias is -9%. At the center of the vessel, the velocity magnitude is estimated to be 0.25 ± 0.023 m/s, compared with an expected peak velocity magnitude of 0.25 m/s, and the beam-to-flow angle is calculated to be 89.3° ± 0.77°, compared with an expected angle value between 89° and 90°. For steering angles up to ±20° degrees, the relative standard deviation is less than 20%. The results also show that a 64-element transducer implementation is feasible, but with a poorer performance compared with a 128-element transducer. The simulation and experimental results demonstrate that the TO method is suitable for use in conjunction with a phased-array transducer, and that 2-D vector velocity estimation is possible down to a depth of 15 cm.

Individual variation in the sequence of ages at peak velocity in seven body dimensions.

Seven body dimensions of 35 Japanese children, 15 boys and 20 girls, were measured longitudinally at six-monthly intervals from 9 through 15 years of age. Spline curves were fitted to each dimension to obtain age at peak velocity and magnitude of peak velocity for each child. Ages at peak velocity for the seven dimensions were chronologically arranged within each individual, and the arrangement was labeled "sequence." Kendall's rank order correlation coefficients among average and individual sequences were calculated to determine whether there was a regular order among individuals in ages at peak velocity of the seven dimensions. There were no sex differences in average sequences, but there was considerable variation among individual sequences. © 1994 Wiley-Liss, Inc.