Magnetic Multi-walled Carbon Nanotubes Research Articles

Immobilization of pullulanase from Bacillus licheniformis on magnetic multi-walled carbon nanotubes for maltooligosaccharide production

Immobilization of pullulanase from Bacillus licheniformis on magnetic multi-walled carbon nanotubes for maltooligosaccharide production

Synthesis of magnetic multi-walled carbon nanotubes with layered double hydroxide (M-MWCNTs@MnAl-LDH) nanocomposite as an adsorbent for lead extraction

MnAl layered double hydroxide hybrid with magnetic-multiwalled carbon nanotubes was synthesized by a hydrothermal method and used for the extraction of Pb(II) (lead) from spices and water samples in the dispersive solid phase microextraction (dSPμE) technique using FAAS. The as-prepared adsorbent MMWCNTs@MnAl-LDH was characterized by XRD, FTIR, EDX, and SEM techniques. Various analytical parameters were optimized, including pH 8, adsorbent dosage of 5 mg, HNO3 eluent concentration of 1 mol L−1, eluent volume of 3 mL, eluent time of 60 s, and sample volume of 20 mL, for quantitative lead recoveries, with an LOD of 0.314 μg L−1, an LOQ of 1.048 μg L−1, and PF of 11.53. Under the optimized conditions, the linearity ranges from 0.5 to 500 μg L−1 (R2 = 0.9997). For the validation test of the established dSPμE procedure, Certified reference materials (CRMs) were used, yielding satisfactory recovery results ranging from 97.8 to 102.7 %. The method was applied to determine lead in turmeric, tap water, and industrial water samples.

Nanoporous carbon derived ZIF-67@MWCNTs-Fe3O4 reinforced hollow fiber to performe hollow fiber solid-phase micro extraction (HF-SPME) coupled with high-performance liquid chromatography to determine deltamethrin and cypermethrin

This study presents a novel micro extraction approach by developing a highly porous and stable Co@N-C/MWCNTs sorbent capable to addresses limitations of traditional sorbents. Zeolitic Imidazolate Framework-67 (ZIF-67) interconnected with magnetic Multi-walled Carbon Nanotubes (MWCNTs) selected as the template for the synthesis of sorbent possess distinctive N-doped and metal (Co) active sites coupled with carbon-rich nanotubes, resulting in a sorbent with a strong affinity to target analytes and excellent chemical stability. For the first time, this material integrated into the pores of a hollow fiber (HF) for a simplified and efficient Hollow Fiber Solid Phase Micro extraction (HF-SPME) method. This innovative integration increases the extraction surface area and minimize matrix interference. Under optimal conditions, the method achieved a wide linear range (0.1–200 μg L−1) for the target analytes, deltamethrin (DLT) and cypermethrin (CPM), the coefficient of determination of 0.9945 for DLT and 0.9982 for CPM. Additionally, it demonstrated excellent analytical performance with: Low limits of detection (LODs): 0.03 µg L−1 for DLT and 0.04 µg L−1 for CPM. Good precision: Inter and intra-day relative standard deviations (RSD) within 2.5–3.4 %. High enrichment factors (EFs): 68–58. The novel Co@N-C/MWCNTs coating, integrated with a hollow fiber, offers a promising advancement for HF-SPME due to its unique properties.

Three-component Synthesis of Tetrahydrobenzo[b]pyrans Using MMWCNTs-PEG-IL as a Novel Magnetic Immobilized Ionic Liquid

Introduction: A novel immobilized imidazolium type ionic liquid was synthesized using poly(ethylene glycol) (PEG) functionalized magnetic multi-walled carbon nanotubes. This immobilized ionic liquid (MMWCNTs-PEG-IL) was characterized by FT-IR, VSM, XRD, FE-SEM and EDX analysis. Method: Then, it was used as a magnetic catalyst in a three-component reaction to yield tetrahydrobenzo[b]pyran derivatives. First, optimized reaction conditions were investigated. A mixture of containing dimedone (1 mmol), malononitrile (1 mmol), benzaldehyde (1.2 mmol) and MMWCNTs-PEG-IL (0.03 g) in H2O/EtOH (5 mL) was stirred at 70 °C. After completion of the reaction, the mixture was cooled. Results: Then, an external magnet was used to separate the magnetic catalyst. This method has many advantages including high reaction yields, high TOFs, using non-toxic solvents, easy handling of catalyst, simple separation of catalyst from reaction medium and short reaction times. Conclusion: Also, the reusability of the magnetic catalyst has been investigated in 7 runs without serious loss of reaction yield.

Magnetic multi-template molecularly imprinted polymers for selective simultaneous extraction of chlorophenols followed by determination using HPLC

Magnetic multi-template molecularly imprinted polymers (M-mt-MIPs) were successfully synthesized by surface imprinting and multi-template imprinting strategy, using polydopamine coated magnetic multi-walled carbon nanotubes as supporting materials, five typical chlorophenols (CPs) as templates, methacrylic acid as functional monomer and ethylene glycol dimethacrylate as cross-linker. Compared to non-imprinted polymers (NIPs), the as-prepared M-mt-MIPs showed high adsorption capacity (32.58‒80.63 mg g−1), rapid mass transfer and specific selectivity for the five targeted CPs, which were applied as magnetic solid-phase extraction (MSPE) adsorbents. Parameters affecting MSPE efficiency were detailed investigated, such as adsorbents dosage, sample pH, extraction time, type and volume of desorption solvent and salt effect. Combined with HPLC-DAD, a simple, rapid and sensitive method was established, showing good linearity (2‒200 μg L−1), low limits of detection (0.32‒0.49 μg L−1), and high enrichment factors (35.2‒108). The developed M-mt-MIPs-MSPE-HPLC method was applied to enrich and determine CPs in tannery wastewater, wet-blue and crust leather, and satisfactory spiking recoveries were attained in the range of 73.95‒109.7% with relative standard deviations (RSDs) of 2.13–8.48%. This study provided a new alternative material and method to rapid simultaneously extract and analyze low concentration of typical CPs in complicated matrices.

Efficient removal of Chromium(VI) from wastewater based on magnetic multiwalled carbon nanotubes coupled with deep eutectic solvents

Industrial wastewater containing heavy metal Cr(VI) seriously affects the health of organisms and may even lead to cancer. Developing efficient adsorbents that can quickly separate heavy metals is crucial for treating wastewater. In this study, magnetic multiwalled carbon nanotubes (MMWCNTs) with moderate particle size and abundant surface active sites were prepared by coating multiwalled carbon nanotubes with magnetic nanoparticles. The results of FTIR, XRD, TG, VSM, BET, and EDS showed MWCNTs completely encapsulated on the surface of the magnetic nanoparticles, with a particle size of approximately 30 nm. Oxygenated groups provided abundant surface active sites and formed numerous mesopores. The response surface methodology was used to optimize the adsorbent dose, adsorption contact time and adsorption temperature, and the removal rate of Cr(VI) was more than 95%. The quasi-second order kinetics and Freundlich adsorption isotherm model explained the adsorption process to Cr(VI). MMWCNTs interacted with Cr(VI) through electrostatic attraction, reduction reactions, complexation, and other means. The extensive hydrogen bonding of the green solvent deep eutectic solvent (DES) was employed to desorb the MMWCNTs and desorption rate exceed 90%. Even after five adsorption-regeneration cycles, the adsorbent maintained a high capacity. In conclusion, these novel MMWCNTs, as efficient adsorbents paired with DES desorption, hold broad potential for application in the treatment of Cr(VI)-contaminated wastewater.

Vanadium speciation using magnetic multi-walled carbon nanotubes coated with ion-imprinted polymer and electrothermal atomic absorption spectrometry

ABSTRACT For selective extraction of vanadium (V) from water and food samples, ion-imprinted polymer was synthesised on magnetic multi-walled carbon nanotubes. For this purpose, the complex of V(V)-8-hydroxyquinoline, 4-vinylpyridine, ethylene glycol dimethacrylate, and magnetic multi-walled carbon nanotubes were used as the template of V(V), functional monomer, cross-linker, and the core, respectively. The prepared sorbent was characterised by FTIR spectroscopy, scanning electron microscopy, X-ray diffraction, energy-dispersion X-ray, and vibrating sample magnetometer. The extracted vanadium (V) was assessed by electrothermal atomic absorption spectrometry. The total vanadium in the solution was extracted and determined after oxidation of V(IV) to V(V) by hydrogen peroxide. Under optimised conditions, limits of detection and quantification of 2.9, and 10.0 ng L−1 were obtained, respectively. The maximum capacity of sorbent was 44.1 mg g−1. The method was successfully employed for the extraction and quantification of vanadium species in different water samples and total vanadium in food samples.

Magnetical multi-walled carbon nanotubes with Lewis acid-base imprinted sites for efficient Ni(II) recovery with high selectivity

The recovery of nickel is crucial for both production and environmental protection. In this work, density functional theory (DFT) was utilized to select a highly affine functional monomer, 2-acetamidoacrylic acid (AAA), for the fabrication of a nickel ion-imprinted adsorbent based on magnetic multi-walled carbon nanotubes. The imprinting technique was used to regulate the electron transfer ability of the N and O atoms, which act as “hard” bases in the functional monomer, facilitating strong interaction with Ni(II) featuring “borderline” acid properties. The adsorption capacity of Ni(II) on adsorbents was high up to 75.06 mg/g, reaching equilibrium in about 50 min, and maintaining high recovery efficiency even after six adsorption-desorption cycles. The adsorbent exhibited a high selectivity for Ni(II), with a distribution coefficient of up to 1366. It is noteworthy that the adsorbent's magnetic properties facilitate easy separation under an external magnetic field, reducing the cost of Ni(II) recycling. The use of XPS characterization and DFT analysis provided in-depth understanding of the adsorption and recognition mechanism. Moreover, the recover efficiency of Ni(II) in acidic mining tailwater reaches 97.66 %, demonstrating a high practical value. This research presents an effective strategy to enhance the practicability of ion imprinted adsorbents by regulating electron transfer ability of the adsorption sites through the imprinting technique.

Nano cerium oxide loaded magnetic multi-walled carbon nanotubes nanocomposite for anti-cancer and anti-bacterial applications

Our study describes the hydrothermal synthesis of CeO2 and Fe3O4 nanoparticles (NPs), and CeO2-loaded magnetic multi-walled carbon nanotubes (MWCNT) nanocomposites (NCs). The obtained CeO2-MMCNTs NC was physicochemically characterized by XRD, FTIR, FESEM, EDX, and UV–visible spectroscopy to assess the NC's crystalline size, functional group, shape, elemental content, and optical characteristics. Further, the disc diffusion method and bacterial reduction assay were used to assess the antibacterial activity of the CeO2-MMCNTs NC. The results showed that NC exhibited better antibacterial activity than cerium oxide NPs. The antioxidant activity of NC was also assessed using the DPPH test, and the findings revealed that the CeO2-MMCNTs NC had stronger scavenging activity than cerium oxide NPs. Next, the MTT test was used to assess the anticancer activity of the NC, and the findings indicated that the CeO2-MMCNTs NCs killed human colon cancer cells with a low IC50 value. These results suggested that CeO2-MMCNTs NC can be used for biomedical applications.

Sorption properties of pristine and functionalized magnetic carbon nanotubes in relation to double-stranded DNA

BackgroundOwing to improvement of the molecular diagnostic methods using purified preparations of nucleic acids (NAs), the development of effective methods providing the isolation of DNA is still relevant. The sorption properties of magnetic multi-walled carbon nanotubes (MWCNTs), oxidized MWCNTs and MWCNTs (pristine and oxidized) modified with polydiallyldimethylammonium chloride (pDADMAC) with respect to double strained DNA have been studied. ResultsIt was shown that in the presence of MWCNTs/pDADMAC particles the DNA molecules were reversibly retained by the particle’s surface. The optimal conditions for each step of DNA extraction from model solutions using the obtained material were selected. A comparative evaluation of the effectiveness of the proposed method for DNA isolation based on the results of spectrophotometry and real-time PCR was carried out. It was shown that the desorbed DNA was efficiently amplified in PCR, inhibition of polymerase did not occurred. Probable mechanisms of DNA retention due to the influence of residual impurities of catalysts in the MWCNT composition, as well as the surface charge of nanotubes are proposed. ConclusionSequentially oxidized and coated with pDADMAC magnetically susceptible CNTs are seemed to be a promising material for development of low-cost systems proving an easy isolation, storage, and subsequent use of dsDNA in molecular diagnostics. The sorption properties of such systems are determined with highly developed specific surface area and their chemical composition.

Facile extraction and determination of organophosphorus pesticides using poly (8-hydroxyquinoline) functionalized magnetic multi-walled carbon nanotubes nanocomposite in water, fruits, and vegetables samples

This study presents a dispersive micro-solid phase extraction (D-μ-SPE) approach for extracting and determining of two organophosphorus pesticides (OPPs), including diazinon and chlorpyrifos as model analytes in various samples. For this purpose, we synthesized, characterized, and utilized magnetic multi-walled carbon nanotubes coated with poly 8-hydroxyquinoline (MWCNTs/Fe3O4@PHQ) as a novel sorbent. The impact of various parameters, including sorbent type, sample pH, sample volume, sorbent amount, desorption solvent (type and volume), extraction time, and ionic strength on the extraction efficiency was investigated and optimized. Following the extraction, the desorbed pesticides in acetone were analyzed using gas chromatography with an FID detector. Under the optimized experimental conditions, the proposed method showed excellent linearity in the range of 3–1000 µg/L, low detection limit (0.9–1.5 µg/L), good relative recoveries (86–101.5 %), and high precision (RSD < 6.5 %). Finally, the applicability of this method was evaluated by analyzing the target OPPs in a variety of real samples, and obtained satisfactory results.

An ultrasensitive smartphone-assisted bicolor-ratiometric fluorescence sensing platform based on a “noise purifier” for point-of-care testing of pathogenic bacteria in food

Non-specific binding in fluorescence resonance energy transfer (FRET) remains a challenge in foodborne pathogen detection, resulting in interference of high background signals. Herein, we innovatively reported a dual-mode FRET sensor based on a “noise purifier” for the ultrasensitive quantification of Escherichia coli O157:H7 in food. An efficient FRET system was constructed with polymyxin B-modified nitrogen-sulfur co-doped graphene quantum dots (N, S-GQDs@PMB) as donors and aptamer-modified yellow carbon dots (Y-CDs@Apt) as acceptors. Magnetic multi-walled carbon nanotubes (Fe@MWCNTs) were employed as a “noise purifier” to reduce the interference of the fluorescence background. Under the background purification mode, the sensitivity of the dual-mode signals of the FRET sensor has increased by an order of magnitude. Additionally, smartphone-assisted colorimetric analysis enabled point-of-care detection of E. coli O157:H7 in real samples. The developed sensing platform based on a “noise purifier” provides a promising method for ultrasensitive on-site testing of trace pathogenic bacteria in various foodstuffs.

Surface molecularly imprinted polymers based on magnetic multi-walled carbon nanotubes for the highly selective purification of resveratrol from crude extracts of Vitis vinifera, Arachis hypogaea, and Polygonum cuspidatum.

In this work, surface molecularly imprinted polymers based on magnetic multi-walled carbon nanotubes were prepared for the specific recognition and adsorption of resveratrol. The functionalization of magnetic multi-walled carbon nanotubes and the synthesis process of surface molecularly imprinted polymers were optimized. Characterizations were performed to demonstrate the successful synthesis of the imprinted materials. The imprinted materials showed satisfactory adsorption capacity of resveratrol (45.73±1.72mg/g) and excellent selectivity (imprinting factor 2.89±0.15). In addition, the imprinted materials were used as adsorbents in molecularly imprinted solid-phase extraction for the purification of resveratrol from crude extracts of some food and medicinal resources, achieving recoveries of 93.69%-95.53% with high purities of 88.37%-92.33%. Moreover, the purified products exhibited extremely strong free radical scavenging activity compared with crude extracts. Overall, this work provided a promising approach for the highly selective purification of resveratrol from natural resources, which would contribute to the application of this valuable compound in the food/nutraceutical fields.

Magnetic multi-walled carbon nanotubes modified with surface-imprinted polymers for ultrasensitive electrochemical detection of trace-level nickel ions in groundwater

Magnetic multi-walled carbon nanotubes (Fe3O4@MWCNTs) were synthesized utilizing a solvothermal technique in this study, followed by the synthesis of Ni(II)-imprinted polymers (IIP) using a surface imprinting technique in this study. The materials' morphologies, structures, and chemical compositions were characterized using several techniques: Fourier transform infrared spectroscopy (FT-IR), Brunauer-Emmett-Teller (BET) analysis, scanning electron microscopy (SEM), transmission electron microscopy (TEM), and X-ray photoelectron spectroscopy (XPS). The IIP was loaded onto a carbon-paste electrode using differential pulsed anodic solution voltammetry (DPASV) to form an electrochemical sensor (IIP-CPE) that could effectively identify Ni(II). The effects of the electrode composition, solution pH, deposition potential, and deposition time on the response of the IIP-CPE electrochemical sensor to Ni(II) peak currents were also investigated. The IIP-CPE demonstrated secondary linearity within the concentration ranges of 0.5–20 μg/L and 20–200 μg/L for Ni(II), with a detection limit of 0.27 μg/L under optimized conditions. It also maintained good selectivity, anti-interference, reproducibility, and stability and showed good accuracy in actual water samples. The constructed IIP-CPE has promising applications for the rapid monitoring trace-level Ni(II) in water bodies.

A disposable homemade screen printed electrode for famotidine analysis using a computer-designed molecularly imprinted polymer based on the MWCNT-Fe3O4 nanocomposite in simulated real samples.

A home-made screen printed electrode (SPE) was designed with a magnetic multi-walled carbon nanotube composite (MWCNT-Fe3O4) and a molecularly imprinted polymer (MIP) for sensitive and selective electrochemical analysis of famotidine (FAM). The SPE was fabricated using non-commercial conductive inks such as carbon and silver inks. The electrodes were printed by a painting technique on polyvinyl chloride (PVC) sheets as a substrate. To optimize the composition of the carbon ink, a mixture design methodology was employed. A computational approach was used to select the functional monomer. The imprinted layer was synthesized by electropolymerization of FAM (template) and pyrrole (PY) (monomer) using cyclic voltammetry (CV) on the working electrode surface modified with the MWCNT-Fe3O4 nanocomposite. Differential pulse voltammetry (DPV) was applied to characterize the template removal and rebinding processes. The Plackett-Burman design (PBD) and central composite design (CCD) investigated the effect of parameters on the MIP/MWCNT-Fe3O4/SPE performance. The sensor exhibited a linear dynamic range of 1-1000 μM (R2 = 0.9919) with a limit of detection (LOD) of 0.027 μM (3sb, n = 3). It demonstrated good repeatability and reproducibility, with relative standard deviations (RSD) of 3.6 and 4.2, respectively. This disposable and cost-effective sensor successfully detected FAM in simulated real samples and correlated well with high-performance liquid chromatography (HPLC) results.

“Five birds one stone” tri-modal monitoring driven lab-on-magnetic aptasensor for accurate pathogen detection and enhanced germicidal application

The effective combination of ultra-precise detection and on-demand sterilization stands out as one of the most valuable antifouling methods to combat pathogenic bacteria source and ensure the environment and food safety. Herein, an innovative “five birds one stone” aptasensor has been reported. It integrates magnetic separation, tri-modal precision detection, and efficient sterilization for monitoring of Staphylococcus aureus. Firstly, as a switch of the aptasensor, aptamer-modified potassium chloride-doped carbon dots (apt/KCl@CDs) could be adsorbed onto the surface of magnetic multi-walled carbon nanotube composites (M-MWCNTs) through π-π stacking, which could be replaced by the specific binding of the target bacteria to the aptamer. The mutual interference between the nanomaterials could be eliminated by this reverse magnetosorption strategy, enhancing the test sensitivity. In addition to the fluorescence properties, the peroxidase activity possessed by apt/KCl@CDs enables the conversion of the (3,3′,5,5′-tetramethylbenzidine) TMB-H2O2 colorimetric system to a photothermal modal. Then, the ultra-precision detection in the assay was achieved by the fluorescence-colorimetric-photothermal tri-modal sensing from the formation of S. aureus-apt/KCl@CDs in the supernatant. Besides, the efficient sterilization could be ensured by adsorbing the apt/KCl@CDs on the surface of S. aureus, generating toxic •OH for direct attacking cells. This was the first report that was more beneficial for bacterial eradication. The detection limits of fluorescence, colorimetric and photothermal modals were 4.81 cfu/mL, 3.40 cfu/mL and 6.74 cfu/mL, respectively. The magnetic nanoplatform integrating tri-modal detection-sterilization meets the demand for highly sensitive and precise detection in different scenarios, providing immediate control for pathogens and broad application prospects.

Magnetic multi-walled carbon nanotubes assisted solid phase extraction and detection of neonicotinoid pesticides in honey and tea samples

In this study, magnetic multi-walled carbon nanotubes (MMWCNTs) were prepared by a one-pot solvothermal method. And they were used as the adsorbent of magnetic solid-phase extraction (MSPE) to extract NEOs. MMWCNTs exhibit good adsorption performance toward NEOs. The adsorption capacities for imidacloprid, thiacloprid, and acetamiprid are 18.4, 25.9, and 18.4 mg g−1, respectively. Also, the adsorption process takes 20 min. The adsorption isotherm fitted to the Langmuir model and the adsorption kinetics was well described by the pseudo-second-order kinetic model. Moreover, the adsorption mechanism was discussed. The MMWCNTs-based MSPE method was combined with field-enhanced sample stacking-capillary electrophoresis (FESS-CE) to realize the sensitive detection of NEOs. The detection limits of NEOs in honey and bottled green tea beverage samples ranged from 7.63 to 16.7 ng g−1. The recoveries were in the range of 84.5 ± 3.2 % to 99.2 ± 1.6 %, with relative standard deviations less than 5.5 %, suggesting the feasibility of the method in actual samples.

Cu(II) and Mo(VI) Schiff base complexes immobilized on magnetic multiwalled carbon nanotubes: Oxidation of olefins and theoretical study

In this study, magnetic multiwalled carbon nanotubes (MMWCNT@SiO2) were anchored with phenylene diamine and subsequently prepared as Schiff base through mono condensation with salicylaldehyde, resulting in MMWCNT@SiO2/Schiff base. This was then complexed with either copper acetate monohydrate or molybdenum oxide to form MMWCNT@SiO2/Schiff base/M (M=Cu, MoO2). The prepared samples were characterized with FTIR, EDS, SEM and XRD. The catalytic behavior of the prepared samples was studied in the oxidation reaction. The results revealed that MMWCNT@SiO2/Schiff base/M (M=Cu, MoO2) effectively catalyzed the oxidation reaction of α-methyl styrene leading to more than 99% conversion and selectivity of acetophenone. In addition to the experimental investigations, theoretical calculations were conducted using DFT calculations to provide further insights into the results.

Solidification/melting enhancement in ice thermal energy storage by synergistic effect of metal foam and carbon nanotube under magnetic field

In this work, water-based magnetic Multi-walled Carbon Nanotube Phase Change Material and Copper Metal Foam (MWCNT PCM-CMF) were combined to improve the performance in ice thermal energy storage. The effect of concentration of magnetic MWCNT, porosity and pore density of CMF and magnetic field intensity on the thermal cycle characteristics including supercooling degree, solidification/melting time, cold storage/release capacity and cold storage/release rate were studied. The results indicated that the optimal magnetic field intensity corresponding to the optimal thermal cycle characteristics decreases with the increased concentration of magnetic MWCNT. Moreover, the addition of magnetic MWCNT-CMF significantly accelerates the solidification process, which is dominated by heat conduction. Although the cold storage capacity of composites was ∼ 94% of pure water, the time required for cold storage was ∼ 52% of pure water as well as the cold storage rate was improved by ∼ 80%. The melting behavior is further improved by arranging gradient CMF. As a result, the combination of 0.04 wt% magnetic MWCNT under 75 mT magnetic field and CMF with 10/5 pore per inch (PPI) gradient pore density at 95% porosity has 86.8% reduction in supercooling degree, 39.8% advance in complete cycle time and the mean rate of energy storage/release is 1.52 times than pure water.

Determination of multiclass contaminants in chilli powder based on magnetic multiwalled carbon nanotubes and UPLC-QTOF/MS

A multiclass analysis approach was developed using magnetic multiwalled carbon nanotubes sorbents and ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UPLC-QTOF/MS) for the rapid screening and simultaneous determination of 216 contaminants including 15 mycotoxins, 9 synthetic colourants, and 192 pesticides in chilli powder. The sample preparation process was optimized. The optimal preparation procedure utilized NaCl and NaAc as the salting-out agents, and Fe3O4-MWCNTs as the sorbents, resulting in reduced chemical consumption, improved cleaning performance, and facilitated high-throughput analysis. The proposed method was validated, and satisfactory parameters were obtained. Approximately 85.6% of the target analytes exhibited a weak matrix effect, with the matrix effects falling within the range of 0.8 ∼ 1.2. The method demonstrated acceptable recoveries of the analytes, falling within the range of 62.14%∼119.76% at three fortified levels with relative standard deviations (RSDs) of less than 20%. Additionally, the method’s limit of quantification (LOQ) ranged from ranged from 0.50 μg·kg−1 to 49.56 μg·kg−1. The method was further applied for analysis of 27 chilli powder samples, demonstrating its potential for screening and quantification of multiclass contaminants for spices.