An effective method of facilitating student learning in a laboratory environment is “practice by doing”. The study of modules related to signal-processing for digital communications requires deep mathematical and theoretical foundations but the practice goal is not really emphasized in the undergraduate curriculum at the University of Mauritius. This causes the students to lose interest in the corresponding modules resulting in high rate of failures. In this work, we propose to develop laboratory experiments with a view to bridge the gap between theoretical and practical aspects in the field of Massive Multiple-Input Multiple-Output (MIMO) systems for 5G cellular networks. Various laboratory scenarios are set up that consider a Maximum Ratio Combining (MRC) receiver in the uplink with an uncorrelated Rayleigh fading channel. Moreover, from a signal processing perspective to enhance the student’s understanding, we analyze the efficiency and error performance of Massive MIMO systems with MPSK and MQAM modulation schemes as well as perfect and imperfect channel estimates. The leading industry software package MATLAB R2022 is used to develop all laboratory experiments and the codes are elaborated in this analysis. Data collected from the experiments are used to generate spectral efficiency and error performance curves which can be used for future research. The findings underscore the significance of accounting for both scenarios and illuminate promising avenues for future research in the realm of massive MIMO education and learning. The assimilation of MATLAB® flowcharts for each MRC receiver, MPSK, and MQAM with perfect and imperfect Channel State Information (CSI) adds further depth to the study, ensuring a comprehensive understanding of the intricacies of massive MIMO systems. Ultimately, this contribution helps in the nurturing of expertise such that future generations of wireless communication pioneers can be inspired.