Stopover sites provide important forage resources and protection from predators to the Aransas-Wood Buffalo population of Whooping Cranes (Grus americana) as they migrate 4000 km across the Great Plains each spring and fall. Given the Whooping Crane's expansive migration corridor, sensitivity to human disturbance, small population size, and protected status under the Endangered Species Act, it is challenging to gather detailed information regarding the particular forage resources that the cranes exploit at various stopover locations. On 22 March 2018 we observed and photo-documented an adult Whooping Crane consuming at least 5 individual juvenile channel catfish (Ictalurus punctatus) after it landed 100 m in front of our Sandhill Crane viewing blind on the south channel of the Platte River. Using the average exposed culmen length of an adult Whooping Crane for reference, we estimated that the length of the channel catfish ranged from 97 mm to 117 mm. Growth estimates developed from the Lower Platte River suggest that the depredated channel catfish were just over one year old. To the best of our knowledge, our observations represent the first definitive record of a Whooping Crane consuming fish in the Platte River, as well as the first record of a Whooping Crane depredating a channel catfish in the Great Plains. Given the relatively long distances at which Whooping Cranes are generally viewed (≥650 m), small-bodied fish may be a more common prey item during migration than indicated by current scientific literature. Our note demonstrates how wildlife photography and ecotourism can contribute to our understanding of species' natural histories.