Background: A stroke can profoundly affect the functionality of the lower limbs. It can greatly influence a person’s ability to walk and maintain balance. disruption of the brain’s ability to control muscle movements, which is often a consequence of a stroke. No published studies focused on Body weight-supported treadmill training in improving lower limb functions. However, body weight treadmill training has proven successful in improving the lower limb functions of acute stroke patients. Aim: To examine the effects of body weight-supported treadmill training in improving the gait and balance in acute stroke patients. Methods: A comprehensive research on Pubmed, Medline, Google Scholar, and Science Direct databases using specific keywords stroke, interventions used in stroke, lower limb functions, and physiotherapy evidence-based database was utilized for quality assessment. Results: This review included ten studies; the findings of this review demonstrate that body weight-supported treadmill training will improve the lower limb functions of acute stroke patients. Conclusion: The results of this review offer abundant proof that body weight-supported treadmill training improves lower limb function in patients suffering from acute stroke. KEYWORDS: Treadmill training with weight support, stroke, evidence-based practice, lower limb functions, and evidence-based physiotherapy