The main activities of Chamber of Commerce and Industry of the Russian Federation (Chamber of Commerce and Industry of the Russian Federation) on assistance to development professional and business education proceeding from one of strategic objectives of social and economic development of the Russian Federation – development of business activity and tasks of strengthening of personnel and enterprise potential are presented in article. Authors expose shortcomings of the existing system of formation of enterprise shots and define the major problems and ways of their overcoming. Regulations on need of creation of educational clusters are formulated: schools – SPO – higher education institutions, their transfer to innovative technologies of training for business. Ways of development of interaction of the state, business, public organizations and educational institutions when training for business activity are offered. The special place in this interaction and in activity of Chamber of Commerce and Industry of the Russian Federation is allocated to financial education of subjects of small and average business in view of the low level of financial literacy of businessmen and to his lag on value from average indicators of the countries of OECD. The question of an important component of social responsibility of business – his interaction with the educational organizations, expansion and activization of participation of representatives of business community in educational process, in grant programs, in the operating bodies, etc. is brought up. The opinion on need of formation of uniform educational system for beginners and the acting businessmen is expressed, tasks of her creation are set and possible ways of their solution are proposed. Authors have offered the concrete directions of strengthening of influence of Chamber of Commerce and Industry of the Russian Federation on processes of training of specialists (participation in formation of the state order for training of specialists taking into account the prospects of development of regional economies, development of dual and network training, development of the competences necessary for the sphere of business, and the programs allowing to form successfully them) and measures for their realization.