Lower Extremity Arteriosclerosis Research Articles

Multislice Computed Tomography Angiography Imaging Diagnosis of Lower Extremity Arteriosclerosis in Patients with Hypertension and Its Correlation with the Level of High-Sensitivity C-Reactive Protein.

The aim of this study was to investigate the relationship between multislice computed tomography (CT) angiography (MSCTA) imaging and high-sensitivity C-reactive protein (hs-CRP) in patients with hypertension and lower extremity arteriosclerosis. 68 hypertensive patients with lower extremity arteriosclerosis were selected as the observation group, and 68 healthy volunteers were selected as the control group to compare the differences in hs-CRP. According to the degree of stenosis, the patients were further divided into five grades: no obvious stenosis, mild stenosis, moderate stenosis, severe stenosis, and occlusion. The correlation between the degree of stenosis and the content of hs-CRP was compared. The changes of hs-CRP content before and after treatment were compared, and the difference of images before and after surgical treatment and the difference of hs-CRP expression in patients with occlusion were compared. Compared with the control group, the content of hs-CRP in the observation group was significantly higher (P < 0.05), and the degree of stenosis was positively correlated with the content of hs-CRP. After two weeks of treatment, the hs-CRP levels of patients with severe stenosis and occlusion were significantly lower than those before treatment (P < 0.01). The level of hs-CRP in patients with occlusion after arterial stent intervention was significantly lower than before, and the images also showed that the blood vessels were significantly expanded. The degree of stenosis in patients with lower extremity arteriosclerosis diagnosed by MSCTA imaging was closely related to the expression of hs-CRP in the patient, and a sustained high concentration of hs-CRP corresponded to a more severe degree of vascular occlusion. In conclusion, the hs-CRP can be used as one of the factors to predict and evaluate the occurrence of cardiovascular and cerebrovascular diseases.

Effect of moxibustion on pain relief in patients with lower extremity arteriosclerosis obliterans of cold coagulation and blood stasis type

Effect of moxibustion on pain relief in patients with lower extremity arteriosclerosis obliterans of cold coagulation and blood stasis type

Therapeutic Effects of Interventional Therapy and Conservative Therapy on Lower Extremity Arteriosclerosis Obliterans and Risk Factors for Prognosis

BackgroundArteriosclerosis Obliterans (ASO) is an important cause for lower limb amputation. We aimed to compare the effects of interventional and conservative therapies on lower extremity ASO, and to analyze the risk factors for prognosis.MethodsNinety-eight eligible patients were randomly divided into experimental (n = 50) and control groups (n = 48). Conservative therapy was conducted for control group, and experimental group was given conservative and interventional therapies. Their baseline clinical data, hospital stay length, claudication distance, Rutherford stage, diseased arteries, Ankle-Brachial Index (ABI), clinical outcomes and adverse events were recorded. Then they were divided into poor (n = 31) and good prognosis groups (n = 67), and risk factors were explored by univariate and multivariate analyses.ResultsThe hospital stay length of experimental group was significantly shorter than that of control group (p < 0.05). After treatment, Rutherford stage decreased, and vascular patency rate and total response rate rose in experimental group (p < 0.05). Claudication distance and ABI significantly increased in both groups compared with those before treatment, especially in experimental group (p < 0.05). The incidence rates of cardiovascular and cerebrovascular events, amputation and death were significantly lower in experimental group (p < 0.05). Age, conservative therapy, smoking, hypertension, diabetes mellitus, hyperlipidemia and fibrinogen were independent risk factors for poor prognosis (p < 0.05). Age of >70 years old and fibrinogen level of >4 g/L had greater effects on prognosis.ConclusionInterventional therapy works well for lower extremity ASO, with high safety, easy recovery and mild complications. Poor prognosis is caused by old age, conservative therapy, smoking, hypertension, diabetes mellitus, hyperlipidemia and increased fibrinogen.

Effect of Different Antithrombotic Regimens to Prevent Postoperative Restenosis in Patients With Lower Extremity Arteriosclerosis.

Effect of Different Antithrombotic Regimens to Prevent Postoperative Restenosis in Patients With Lower Extremity Arteriosclerosis.

Expression and clinical significance of HSP27 and its phosphorylation in lower extremity arteriosclerosis obliterans

ObjectivesThis study set out to analyze the difference of heat shock protein 27 (HSP27) and its phosphorylation in patients with lower extremity arteriosclerosis obliterans (LEASO) at different stages. This research also examined their clinical significance in this disease.MethodsBlood samples from 60 patients with LEASO were collected and divided into two groups according to ankle-brachial index (ABI): group A (ABI ≤ 0.43) and group B (ABI > 0.43). The expression of HSP27 in each stage of Fontaine was measured by ELISA, and the difference of HSP27 concentration and ABI between the two groups was analyzed. Meanwhile, three normal femoral artery specimens (normal group) and three atherosclerotic femoral artery specimens (lesion group) were collected, and HSP27 and its Phospho-HSP27 (Ser15), Phospho-HSP27 (Ser78) and Phospho-HSP27 (Ser82) were detected by western blotting. The data of the protein level between the normal group and the lesion group was made a statistical analysis.ResultsHSP27 concentration in group A was (40.73 ± 15.99) ng/ml, and ABI was 0.26 ± 0.20. HSP27 concentration in group B was (66.30 ± 24.70) ng/ml, and ABI was 0.64 ± 0.20. The protein expression of HSP27 and its phosphorylation in the normal group was 0.82 ± 0.13, 0.66 ± 0.12, 0.91 ± 0.24 and 0.90 ± 0.16, respectively; the protein expression of the lesion group was 0.45 ± 0.08, 0.42 ± 0.09, 0.39 ± 0.12 and 0.58 ± 0.11.ConclusionPatients with higher LEASO Fontaine stage and lower ABI had a lower HSP27 concentration. Serum HSP27 concentration was negatively correlated with the severity of LEASO, while HSP27 concentration was positively correlated with ABI value. The content of HSP27 and its phosphorylation of lesion group is significantly lower than that of normal group, which may be closely related to the occurrence and development of atherosclerosis.

Dengzhan Shengmai capsule in treatment of lower extremity arteriosclerosis obliterans

Objective To observe the clinical effect of Dengzhan Shengmai capsule in the treatment of lower extremity arteriosclerosis obliterans. Methods 60 patients were randomly divided into a control group and a treatment group, 30 for each group. The control group was treated with conventional western medicine alprostadil, while the treatment group was treated with oral Dengzhan Shengmai capsule on the basis of alprostadil, 2 capsules each time, three times a day. The two groups were treated for 14 days as a cycle and 4 cycles as a treatment course. The treatment effects were compared between these two groups. Results The total effective rate of the treatment group was 96.7%, and that of the control group 80.0% (P<0.05). After the treatment, the ABI and TBI increased significantly in both groups (all P<0.05), and the changes of ABI and TBI in the treatment group were more significant than those in the control group (both P<0.05). After the treatment, the internal diameters of the posterior femoral artery, the posterior tibial artery and the dorsal pedal artery of the two groups increased significantly (all P<0.05). In addition, the hemorheology and endothelium of the two groups were significantly improved after treatment, and were better in the treatment group (all P<0.05). Conclusions Dengzhan Shengmai capsule is effective in treating lower extremity arteriosclerosis obliterans, through improving microcirculation, inhibiting thrombosis, and regulating the release of vascular endothelial factors. Key words: Dengzhan Shengmai capsule; Lower extremity arteriosclerosis obliterans; Efficacy

Progress in the treatment of lower extremity arteriosclerosis obliterans with intracavitary volume reduction

Arteriosclerosis obliterans(ASO) of lower limbs is a common vascular disease in clinic. The main treatment methods of ASO include medical treatment, surgical treatment and endovascular treatment. Endovascular therapy has been widely used in clinical treatment because of its small trauma and rapid recovery. Endovascular therapy includes percutaneous transluminal angioplasty and intraluminal volume reduction. Intravascular volume reduction has become the focus of the development of endovascular therapy. It is a prerequisite for the treatment of ASO to master various intraluminal therapy methods. This article focuses on the progress of intracavitary volume reduction therapy in ASO. Key words: Arteriosclerosis; Arterial occlusive diseases; Therapeutic uses; Intracavitary volume reduction

Clinical follow-up study of paclitaxel-coated balloon in the treatment of symptomatic lower extremity arteriosclerosis obliterans

Objective To investigate the clinical effect of paclitaxel coated balloon in the treatment of symptomatic lower extremity arteriosclerosis obliterans. Methods From January 2016 to April 2017, 64 patients with symptomatic lower limb arteriosclerosis obliterans (ASO) of femoral and popliteal artery stenosis admitted to Chongming Branch Xinhua Hospital affiliated to Shanghai Jiaotong University School of Medicine were selected as the research subjects.According to the principle of randomization, they were divided into two groups, 32 cases in each group.In the drug-coated group, ordinary balloon was pre-expanded, and then paclitaxel drug-coated balloon was used to expand.If there were still retraction and stenosis of diseased vessels, which affected the blood flow of lower limbs, remedial stents were implanted.Bare stent group used a slightly smaller balloon to pre-expand superficial femoral artery and then release the stent.After one year follow-up, the changes of ankle-brachial index (ABI), restenosis rate of target lesion vessels, Rutherford grading changes, clinical drive target vessel revascularization rate, perioperative period, death rate of patients during follow-up period, amputation rate and complication rate were observed. Results There were no amputations or deaths in the whole group during the perioperative period and follow-up.The incidence of complications in the drug-coated group was 3.1% (1/32), significantly lower than that in the bare stent group 18.8% (6/32) (χ2=4.010, P=0.045). Before treatment, the ABI of patients in drug-coated group and bare stent group at 6 months and 12 months after treatment were significantly different (Finter-group=7.028, Pinter-group=0.024, Fintra-group=219.028, Pintra-group=0.000, Finteraction=350.028, Pinteraction=0.000), and ABI of the two groups at 12 months after treatment were (0.73±0.11) and (0.68±0.09), respectively, the difference was statistically significant (t=1.990, P=0.025). Six months after operation, the restenosis rates of target lesions in the two groups were 9.4%(3/32) and 15.6%(5/32), respectively, with no significant difference (χ2=0.571, P=0.450); The restenosis rate of bare stent group was 37.5%(12/32) 12 months after operation, which was significantly higher than that of drug-coated group by 15.6%(5/32) (χ2=3.925, P=0.048). Clinical observation results showed that 12 months after operation, the target-lesion revascularization (TLR) of the drug-coated group was 3.1% (1/32) and that of the bare stent group was 9.4% (3/32), with no significant difference.Rutherford grading was improved in both groups(χ2=1.067, P>0.05). Conclusion Paclitaxel drug-coated balloon is safe and effective in the treatment of symptomatic lower limb arteriosclerosis obliterans, which is worthy of clinical application. Key words: Arterial occlusion of the lower limb; Drug-coated balloon; Paclitaxel; Restenosis; Ankle brachial index

The dynamic changes of endothelin-1 and NO and the value of predicting restenosis in lower extremity arteriosclerosis obliterans after interventional therapy

The dynamic changes of endothelin-1 and NO and the value of predicting restenosis in lower extremity arteriosclerosis obliterans after interventional therapy

Effect of individual exercise prescription on walking ability of patients with arteriosclerosis obliterans of lower limbs

Objective To explore whether individualized exercise prescription can improve the walking ability of patients with lower extremity arteriosclerosis occlusion (ASO). Methods A total of 64 ASO patients with ankle brachial index (ABI) between 0.6 and 0.9 were randomly divided into the observation group (32 cases) and the control group (32 cases), Patients in the control group received routine nursing intervention, and patients in the observation group received nursing intervention based on individualized exercise prescription, ABI and walking impaired questionnaire (WIQ) scales were measured at admission and 12 weeks after intervention. Results There was no statistically significant difference in ABI values before and after the intervention of the control group (P > 0.05), and ABI values before and after the intervention of the observation group were 0.72 + 0.15 and 0.77 + 0.13 respectively (t=2.254, P 0.05) in the two groups; the walking distance and walking speed after intervention in the observation group were (498.38±77.11) m and (50.44±11.27); the control group was (461.72±64.64) m and (44.02±9.86), and the differences were statistically significant (t=2.06, 2.43, P < 0.05). Conclusions Individualized exercise prescription can improve the degree of ischemia of the affected limb, improve the walking distance and walking speed of the patients, and it is convenient to implement and worthy of clinical promotion. Key words: Individualized exercise prescription; Arteriosclerosis obliterans of lower extremities; Ability of walking

Guidelines on the diagnosis and treatment of diabetic foot

Diabetic foot is one of the serious chronic complications caused by diabetes mellitus. The guidelines introduce the fundamental concepts of diabetic foot, distinction between diabetic lower-extremity ischemia and lower-extremity arteriosclerosis with concurrent diabetes mellitus, pathological features of diabetic foot lesions, and the prognosis. This article focuses on the diagnosis and treatment of diabetic foot, including endovascular arterial revascularization of lower extremity, arterial bypass reconstruction, and stem cell transplantation. The selection of therapeutic schemes for the larger, middle, and small artery lesions and the perioperative management are also discussed in detail.

Inhibiting lncRNA ROR suppresses growth, migration and angiogenesis in microvascular endothelial cells by up-regulating miR-26.

Lower extremity arteriosclerosis is one of leading causes of death worldwide. Arteriosclerosis is closely related to microvascular endothelial cells. This study was aimed to explore the role of long non-coding RNA ROR in regulations of growth, migration, and angiogenesis of microvascular endothelial cells. Angiogenesis was determined by the number of tube-like cells on a matrigel extracellular matrix. Cell viability, apoptosis, and migration were determined by CCK-8 assay, PI/FITC-Annexin V staining method, and transwell assay, respectively. Relative RNA expression of ROR, miR-26, and angiogenesis-associated genes were analyzed by qRT-PCR. The protein expression of apoptosis- and angiogenesis-associated genes, as well as main factors in NF-κB and JAK1/STAT3 pathways, were analyzed by Western blot. LncRNA ROR silence inhibited viability, migration, and angiogenesis of HMEC-1 cells but promoted apoptosis of them. miR-26 expression was promoted after knocking down ROR expression. miR-26 overexpression enhanced the inhibitory effects of ROR silence on growth, migration, and angiogenesis in HMEC-1 cells, whereas, miR-26 silence impaired the effects of ROR silence. Finally, we found that NF-κB and JAK1/STAT3 signaling pathways were inhibited by ROR down-regulation. Similarly, miR-26 overexpression enhanced the inhibitory effect of ROR down-regulation on the pathways and miR-26 inhibition abrogated it. Down-regulating lncRNA ROR inhibited growth, migration and angiogenesis of microvascular endothelial cells possibly through up-regulation of miR-26. During this process, the activations of NF-κB and JAK1/STAT3 pathways were inhibited after interaction of ROR and miR-26.

Application of TurboHawk plaque resection system in the treatment of lower extremity arteriosclerosis obliterans

Objective To evaluate the efficacy and safety of TurboHawk plaque resection system in the treatment of lower extremity arteriosclerosis obliterans. Methods Clinical data of 36 patients with atherosclerotic occlusion of lower extremity treated with TurboHawk from January 2016 to August 2017 were retrospectively collected. The characteristics of lesion, improvement of symptoms, ankle brachial index (ABI) and postoperative complications were analyzed. The measurement data were expressed as (±s), All patients were reviewed every 3 months after operation, followed up for 3-18 months, with an average of (9±0.5) months. And the ABI comparison before and after treatment were performed by paired t test; the counting data were expressed as rate (%), and the comparison of different stages was performed by chi-square test. Results In 36 patients, the technical success rate was 100%, and the symptoms of lower limbs were significantly improved. The ABI (0.85±0.07) and ABI (0.75±0.10) were significantly better in 3 days and in 3 months after operation than before operation (0.29±0.10)(t=37.76, P<0.001). Postoperative complications occurred in 2 cases, in one case, the artery dissection was covered with a bare scaffold, and in the other case, the blood vessel was ruptured after resection, and was closured by using balloon angioplasty. Conclusion TurboHawk plaque resection system is an effective, less traumatic and safer option for the treatment of lower extremity arteriosclerosis obliterans. Key words: Atherectomy; Arteriosclerosis obliterans; Lower extremity; Therapeutic uses; TurboHawk

Assessment of ankle–brachial pressure index in elderly patients as screening for lower extremity ischemia in the context of medical test method used

ABSTRAKTWstęp: Wskaźnik kostka–ramię (ABI) wyraża stosunek ciśnienia skurczowego w tętnicach zlokalizowanych na podudziach, tj. tętnicy piszczelowej tylnej bądź tętnicy grzbietowej stopy, do ciśnienia panującego w tętnicy ramiennej.Celem niniejszej pracy było porównanie wartości ABI mierzonego za pomocą detektora dopplerowskiego fali ciągłej (DDFC) oraz urządzenia BOSO ABI-SYSTEM 100 (ABIs) u seniorów, a także próba określenia czynników determinujących wyniki badań w porównaniu z pacjentami młodszymi.Materiały i metody: Przedmiotem przeprowadzonego badania był pomiar ABI przy użyciu DDFC oraz urządzenia ABIs wśród pacjentów z przewlekłą niewydolnością żylną, niedokrwieniem kończyn dolnych oraz cukrzycą. Badania przeprowadzono po uzyskaniu zgody Komisji Bioetycznej nr KB 523/2016 z dnia 28.06.2017 r. przy Uniwersytecie Mikołaja Kopernika w Toruniu, Collegium Medicum w Bydgoszczy w okresie 28.06.2016–6.04.2017 r. Miejscem realizacji badań była Poradnia Leczenia Ran Przewlekłych w Szpitalu Uniwersyteckim nr 1 im. Ludwika Rydygiera w Bydgoszczy.Wyniki: Średnia wartość ABI wśród wszystkich badanych wyniosła w kończynach: prawej – 0,999 (DDFC), 0,954 (ABIs), lewej – 0,980 (DDFC) i 0,945 (ABIs); z odchyleniem standardowym 32,9% (DDFC), 30,1% (ABIs) dla kończyny prawej i 34,2% (DDFC), 32,1% (ABIs) dla kończyny lewej wartości średniej, co świadczy o dużym zróżnicowaniu wyników. Średnio najwyższy wskaźnik uzyskali pacjenci z cukrzycą (1,163 DDFC – dla kończyny prawej, 1,196 DDFC – dla kończyny lewej), a najniższy – badani z miażdżycą (0,750 – kończyna prawa, 0,684 – kończyna lewa DDFC).Wnioski: Wyniki pomiaru ABI za pomocą DDFC oraz ABIs nie wykazują istotnych statystycznie różnic mogących wpływać na postawienie diagnozy. Płeć, wiek, wykształcenie i analiza kliniczna pacjentów częściowo określiły wyniki testu ABI. Pacjenci w wieku 61–70 lat i najstarsi mieli najniższe wartości ABI.

Analysis of psychological distress in patients with lower extremity arteriosclerosis obliterans

Objective To investigate the degree of psychological distress in patients with lower extremity arteriosclerosis obliterans, and to understand the causes and to analyze the influencing factors. Methods The general information questionnaire, psychological distress thermometer, family APGAR index and family burden scale questionnaire were used to conduct a cross-sectional survey in 145 patients with obliterans in hospital during the period from July 2015 to July 2017. Results The average score of psychological pain of all patients was (4.7±2.2) points, the patients with significant psychological distress was 102 cases, accounting for 70.3% (DT score≥4 points). The main reason caused by lower extremity arterial occlusive disease in patients with psychological distress among the top 10 were: pain, anxiety, sleep problems, physical activity, work/school, restricted travel, numbness, fatigue, constipation, economic problems. Multiple linear regression analysis showed that the hospitalization, duration of illness, family care and family burden of the disease affected the scores of psychological pain in different seasons (P<0.05). Conclusions The patients with lower extremity arteriosclerosis obliterans have severe psychological pain, so the targeted measures should be taken to prevent and treat the risk factors. Key words: Arteriosclerosis obliterans of lower extremity; Psychological pain; Influencing factor; Distress thermometer

Clinical study of mechanical thrombectomy in treating in-stent restenosis of lower extremity arteriosclerosis obliterans

Objective To evaluate the safety and efficacy of mechanical thrombectomy in treating in-stent restenosis of lower extremity arteriosclerosis obliterans. Methods From May 2015 to Sep 2016, the clinical data of 9 cases of lower extremity arteriosclerosis obliterans who were with in-stent restenosis(3 were stent graft)were retrospectively collected, and of which 7 were males and 2 were females with a mean age of (75.4±6.3) years old. All the cases were treated by mechanical thrombectomy of Rotarex catheter. All the patients were diagnosed via low-extremity artery CTA, and treated by means of the Rotarex catheter, combined with angioplasty and stent if necessary. All patients received antiplatelet therapy. Doppler ultrasonography was taken during the followed-up. Results All the 9 cases were successed in technology, without complications in hospital. All patients received Rotarex mechanical thrombectomy. Six of which used balloon and 1 stent implanted. The ABI increased from 0.29±0.07 to 0.88±0.07 after treatment, the difference was statistically significant (t=28.875, P<0.05) . All the patients were followed up for 3—18(median time, 11.5)months. No death and symptoms recurrence appeared during the follow-up. Conclusions Mechanical thrombectomy using Rotarex catheter is a safe and effective treatment for in-stent restenosis in lower extremity arterial diseases. Key words: Arteriosclerosis obliterans; Lower extremity; Radiology, interventional; In-stent restenosis; Mechanical thrombectomy

Nursing research progress of lower limb ischemic pain

Lower limb ischemic pain is the disease of lower extremity arteriosclerosis occlusion, buerger's disease, acute lower limb artery embolization common pain and other regular symptoms of vascular surgical disease. The pain is unbearabl, and no special treatment, seriously affect the quality of life. In this paper will review the related research at home and abroad, from the pain of the characteristics of the relevant assessment tools, the characteristics of the pain, the pain of the related nursing measures this three aspects, in order to provide evidence for reducing the patient's physical and mental pain, and promoting the recovery of patients effectively for the patients with lower limb ischemic pain. Key words: Review; Pain; Ischemia; Nursing care; Assessment

Effect analysis of the technique of retrograde puncture of popliteal artery applied in the interventional therapy of lower extremity arteriosclerosis obliterans patients

To investigate the effectiveness of retrograde puncture of popliteal artery in lower extremity arteriosclerosis obliterans(ASO) patients classified as TASC(Tans-Atlantic Inter-Society Consensus)C/D. Retrospective analysis of 35 lower extremity ASO patients, 28 male and 7 female , the mean age was 72±8, 23 cases of Rutherford 3, 8 cases of Rutherford 4 and 4 cases of Rutherford 5. Preoperative ABI was 0.35±0.14, Lesion length in CT angiography (CTA) was (18±5) cm. The technique success rate of 35 cases was 100%. The puncture time was (6±4) min.6 cases used 4 F sheath and 29 cases used no sheath technology at the puncture site. In 27 cases guide wires passed retrograde through the occluded superficial femoral artery lesion and returned to the true lumen.8 cases of SAFARI technology to established the guild wire track. The complication rate of retrograde puncture was 14.2%(5/35), 2 cases of postoperative hematoma appeared at the puncture site the next day, 2 cases of pseudoaneurysms emerged and 1 case of postoperative arteriovenous fistula at the puncture site of popliteal area were found by Doppler ultrasonography before discharged. All 5 patients were recovered by conservative treatment. The retrograde puncture of popliteal artery is a safe and reliable method. Key words: Arteriosclerosis; Popliteal artery; Punctures

Low concentration of iodixanol used in CT angiography of lower extremity arteriosclerosis obliterans

To evaluate the clinical diagnostic value of low concentration of iodixanol used in CT angiography (CTA) of lower extremity arteriosclerosis obliterans (LEASO). 42 patients which were suspect diagnosed with LEASO were divided to A group (270 mgI/ml iodixanol, tube voltage 100 kV) and B group (350 mgI/ml iohexol, tube voltage 120 kV), 21 patients in each group. Measure the body mass index (BMI) before the CTA of lower extremity. CTA results were analyzed with the digital subtraction angiography (DSA) as the "gold standard". There were no statistical difference of age, gender, BMI and CT value of the bifurcation of profunda femoral artery and superficial femoral artery, upper segment of anterior tibial artery and posterior tibial artery between A and B group. The diagnostic sensitivity and specificity of A and B groups of CTA were 97.0%, 99.1% and 98.3%, 99.5% for occlusion. Regard artery more than moderate stenosis (include moderate stenosis) as the overall statistics, the diagnostic sensitivity and specificity of A and B groups of CTA were 99.2%, 99.3% and 99.1%, 99.3%, the accuracy were 92.9% and 93.0%, the positive predictive and negative predictive value were 96.9%, 99.3% and 96.6%, 99.3%, respectively. The kappa value of A and B groups of CTA and DSA consistency test were 0.930 and 0.927, respectively. The CTA with low concentration of iodixanol combine with low tube voltage can achieve superior conventional scanning imaging features, and has great clinical value in the diagnosis of LEASO, also is an effective method for the inspection, evaluation and follow-up.

Study on the correlation of lower extremity arterial vessels by ultrasonography and atherosclerosis detection indicators

To examine the correlation between lower extremity artery ultrasound and arteriosclerosis detection indicators, including ankle-brachial index (ABI) and Cardiac Ankle Vascular Index (CAVI). According to the level of lower extremity arterial disease by ultrasonography, 320 patients were divided into 3 groups (normal group, mild lesions group and severe lesions group). Comparative analysis of the difference of arteriosclerosis detection indicators among the groups, including ABI and CAVI . To analyze the correlation of two test results and explore the risk factors of lower extremity atherosclerotic lesions. To compare ABI among the three groups, the differences were statistically significant (P < 0.05 ) . Lower extremity arterial disease was negatively correlated with ABI and positively correlated with CAVI (P = 0.000 ). Using Logistic regression analysis: age, gender, diabetes, pulse pressure is the impact of lower extremity arterial disease risk factors. ABI and CAVI can be used as reliable indicators for the screening of artery stenosis, occlusion and atherosclerosis, combined with color Doppler ultrasonography can improve the diagnosis rate of lower extremity arterial disease.