In this work, we focus on two important aspects of modern cosmology: reheating and Hubble constant tension within the framework of a unified cosmic theory, namely the quintessential inflation connecting the early inflationary era and late-time cosmic acceleration. In the context of reheating, we use instant preheating and gravitational reheating, two viable reheating mechanisms when the evolution of the universe is not affected by an oscillating regime. After obtaining the reheating temperature, we analyze the number of e-folds and establish its relationship with the reheating temperature. This allows us to connect, for different quintessential inflation models (in particular for models coming from super-symmetric theories such as α-attractors), the reheating temperature with the spectral index of scalar perturbations, thereby enabling us to constrain its values. In the second part of this article, we explore various alternatives to address the H0 tension. From our perspective, this tension suggests that the simple Λ-Cold Dark Matter model, used as the baseline by the Planck team, needs to be refined in order to reconcile its results with the late-time measurements of the Hubble constant. Initially, we establish that quintessential inflation alone cannot mitigate the Hubble tension by solely deviating from the concordance model at low redshifts. The introduction of a phantom fluid, capable of increasing the Hubble rate at the present time, becomes a crucial element in alleviating the Hubble tension, resulting in a deviation from the Λ-Cold Dark Matter model only at low redshifts. On a different note, by utilizing quintessential inflation as a source of early dark energy, thereby diminishing the physical size of the sound horizon close to the baryon–photon decoupling redshift, we observe a reduction in the Hubble tension. This alternative avenue, which has the same effect of a cosmological constant changing its scale close to the recombination, sheds light on the nuanced interplay between the quintessential inflation and the Hubble tension, offering a distinct perspective on addressing this cosmological challenge.