This paper presents an energy-efficient I/O interface with a 3-D flip chip package. The I/O interface is composed of a transmitter and a receiver. The transmitter consists of a pseudo-random bit sequence generator and an output buffer. The receiver employs a full-rate forwarded-clock structure that is composed of a novel current-domain equalizing sampler with a 10 Gb/s sampling rate for data recovery and a low-power clock recovery circuit with dual-injection-locked oscillators. The proposed sampler utilizes a current sampling structure and merges a shunt-peaked amplifier with 20-GHz bandwidth for data recovery. Meanwhile, clock recovery implements a phase interpolator achieving phase deskew larger than one data unit interval. A 3-D flip chip package with silicon substrate is utilized for multiple I/O channels integration. The chip was fabricated in a 65-nm CMOS process in an area of 0.42 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> . The measurement results show that the I/O interface can realize a 5-10-Gb/s data rate with bit error rate less than 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-12</sup> across 5-mm redistribution layers in a silicon substrate whose loss is 3~4 dB at Nyquist bandwidth.