Lot Of Exploration Research Articles

Simulation of boost path and phase control method in supercritical CO2 pipeline commissioning process

CO2 pipeline can be applied to Enhanced Oil Recovery (EOR) projects and CO2 geological storage projects, and has high engineering application value. However, pipeline transportation of CO2 is a high-risk link in CO2 storage projects. The phase state commonly used to transport CO2 is a supercritical state with both gaseous and liquid characteristics, and there are also great challenges in the field of pipeline transportation. The existing researches have carried out a lot of exploration and application development in the heat transfer, phase change, transient and special conditions of supercritical CO2 pipeline operation.In this paper, the modeling and exploration of the commissioning process before the formal operation of the supercritical CO2 pipeline are carried out, and the boost path of the supercritical CO2 pipeline in the phase diagram under different working conditions is obtained. The model developed in this paper is based on the sensitivity analysis of the effects of variables such as ground temperature, filling pressure speed, and whether to perform pressure-stabilizing leak detection operations. The step-up path in the phase diagram of the CO2 pipeline commissioning process and the adjustment control method are obtained. And the critical temperature of each working condition that cannot avoid phase transition, thus contributing to the existing knowledge system in this field.

Significant Improvement in Thermoelectric Properties of Carbon-Reinforced Cementitious Composites Achieved by Regulating the Graphitization Degree of Expanded Graphite.

Building structures are exposed to direct sunlight for a long time, accumulating a large amount of low-grade thermal energy, which aggravates environmental pollution and energy consumption. Thermoelectric cement-based composites can realize the interconversion of thermal and electrical energy, showing great potential benefits in large-scale heat collection and energy conversion. Although a lot of exploration and research has been carried out on the thermoelectric properties of cement-based composites reinforced with carbon materials, the contribution of the characteristics of carbon materials, such as the graphitization degree, to the thermoelectric properties of cement-based composites is still unclear. In this article, the graphitization degree of expanded graphite (EG) was modulated by etching EG with an acid solution. The low graphitization degree improves the effective mass of carriers and aggravates the electron and phonon scattering at the interface of EG/cement-based composites. Low thermal conductivity was obtained while increasing the Seebeck coefficient of EG/cement-based composites. The power factor (17.1 μW m-1 K-2) and thermoelectric figure of merit (2.95 × 10-3) of the sample are increased by 18.6 times and 44.2 times, respectively, achieving the highest thermoelectric performance in cement-based composites reinforced with carbon materials. This study provides a direction for improving the thermoelectric properties of cement-based composites by structural regulation of carbon materials.

Socioemotional Development of Adolescence In Sport Activity

During adolescence whose experiencing an identity crisis, they do a lot of exploration in various activities, including sports. This study aims to focus on the socioemotional development of adolescents in sports activities based on Erikson's theory. The subjects of this study were adolescents aged 12-23 years and got 212 participants. The method used in this research is descriptive. The results of this study are 1)identity crisis characterized by adolescents seeking standards for exercise; 2) there are 13 participants who found the goal of career in the field of sports, meaning that they had passed a period of identity crisis; 3) there are 155 participants exercise because they are influenced by group, not their parents or self-awareness; 4) the self-standardization period proven by setting standards in sports; 5) among 212 participants, 134 of them have not found self-standardization when the target has been achieved; 6) there are 125 out of 212 participants who have target for appearance rather than health, meaning that there is egocentrism in the participants; 7) among 212 participants, 193 of them stated that they had more stable emotions after exercising. Exercising is one of the explorations that teenagers can do to get through the identity crisis. Some participants were able to get through the identity crisis by exercising and some had to do further exploration.

A stable oxygen evolution splitting electrocatalysts high entropy alloy FeCoNiMnMo in simulated seawater

• FeCoNiMnMo electrode possesses a low overpotential of 237 mV at j=10 mA cm −2 and great stability of 200 h at 100 mA cm −2 in simulated seawater. • The composite protective layer with K 2 MoO 4 is the key factor for the electrode in chlorine resistance. • K 2 MoO 4 has the strongest adsorption energy with Cl − , which protects other oxides from Cl − corrosion. • Only the self-generated K 2 MoO 4 can protect the electrode by repelling Cl − . • The high entropy effect greatly inhibits the dissolution of metals. Stabilizing anode for oxygen evolution (OER) in chlorine-containing electrolytes is a significant challenge. Adding corrosion inhibitors in electrolytes can alleviate this problem, but the type and dosage of corrosion inhibitors need a lot of exploration, and side reactions may occur to reduce current efficiency. Herein, we prepared a FeCoNiMnMo High entropy alloy (HEA) electrode for OER in simulated seawater without corrosion inhibitors. It exhibits great electrocatalytic activity (overpotential ( η ) = 237 mV at 10 mA cm –2 ) and excellent stability (200 h at 100 mA cm –2 ). Experiments and Density Functional Theory (DFT) calculation show that the protective layer containing K 2 MoO 4 is the crucial factor for chlorine resistance of FeCoNiMnMo electrode. The tightly adsorbed state of Cl – and K 2 MoO 4 ensures that other oxides are not corroded. And the externally added K 2 MoO 4 cannot protect the electrode. In addition, the high-entropy effect of HEA reduces the dissolution of the alloy. This work provides an efficient way to prepare a noble-free HEA catalyst that can stabilize oxygen evolution in corrosive electrolytes.

New Targets of CAR-T Therapy for B-cell lymphoma

B-cell lymphoma is a kind of hematologic malignancy with high morbidity and mortality, which is usually treated by chemoimmunotherapy followed by an autologous transplant. But the traditional therapy usually leads to relapse and refractory. Now FDA has approved four CAR-T cell products that all target CD19 to give relapsed or refractory patients another chance to control cancer. These achievements may thank the CD19, but the CD19 also leads to some problems including the off-tumor effect and antigen escape that result in off-tumor effects and relapses. These problems prevent CAR-T therapy from being widely used in treating B-cell lymphoma. To solve these problems, new targets should be discovered. Scientists have already done a lot of exploration in this area. To give the scientists some directions, this paper will briefly introduce the two problems, the characteristics that are required for the ideal targets, and some ideal future targets which are understudy now.

Mechanism of Forming Low Resistivity in Shale Reservoirs

In the oil and gas industry, traditional logging mostly deems that oil and gas reservoirs are characterized by high resistivity, whereas the water layer is often by low resistivity. However, a lot of exploration and development practices on shale gas reservoirs in Sichuan Basin, China, prove that it is hard to characterize a functional relation between resistivity and water saturation using the Archie equation. Therefore, to make clear the mechanism to form low resistivity in shale gas reservoirs, the matrix resistivity was calculated through the percolation network simulation based on pore structure characteristics and mineral compositional parameters. Moreover, the resistivity in low-resistivity laminations of shale was measured through the finite element simulation. In addition, the reasons for such low resistivity in shale were analyzed according to the resistivity-forming mechanism, and the effects of penetration degree, width, quantity, and spatial distribution of the laminations on the resistivity were worked out. Those may provide theoretical support for explaining the phenomenon of low-resistivity gas reservoirs.

AI Doc Helper

For numerous times, numerous people have failed due to undetected conditions. Early discovery of these conditions at the micro bracket stage can be useful for furnishing proper treatment of the cases at an early stage and could have saved a lot of lives. A lot of exploration is being done to describe these conditions at the foremost. Thus, a computer-backed or Artificial Intelligence approach for detecting conditions at the early stage is being proposed, which makes use of machine, literacy and deep literacy algorithms for detecting conditions. This system will describe all general conditions similar to different types of cancer, malaria, diabetic retinopathy, etc. AI-Doc Helper is being proposed as there's no system available that detects all these general conditions.

Choice of digestive tract reconstruction in upper gastric cancer

With the increasing incidence of upper gastric cancer and early gastric cancer, surgeons have gradually paid attention to the selection of appropriate digestive tract reconstruction methods. At present, the safety of surgery is no longer the main aim pursued by surgeons, and the focus of surgery has gradually changed to postoperative quality of life. Surgical procedures for upper gastric cancer include total gastrectomy (TG) and proximal gastrectomy (PG). Roux-en-Y anastomosis is recommended for digestive tract reconstruction after TG. The classic method of digestive tract reconstruction after PG is distal residual stomach and esophageal anastomosis. However, to prevent esophageal reflux caused by PG, a lot of explorations have been carried out over the years, including tubular gastroesophageal anastomosis, double-flap technique (Kamikawa anastomosis), interposition jejunum, double-tract reconstruction and so on. But the appropriate method of digestive tract reconstruction for upper gastric cancer is still controversial. In this paper, based on literatures and our clinical experience, the selection, surgical difficulties and techniques of digestive tract reconstruction after PG are discussed.

The Transformation of Smart City Concept in Urban Development (Case Study: Semarang City)

The urban development in line with technology growth has created a smart city concept. Semarang city is one of the metropolitan cities that has applied a smart city concept since 2013 by implementing information technology in their programs. It was successfully made Semarang getting an award as the best city of Development Regional Awards by Bappenas (Ministry of National Development Planning) in 2019. But over time, the smart city concept in Semarang has transformed in its implementation to solve the city’s problems and adapt to their needs. The purpose of this study is to describe the phenomena in the transformation of the smart city concept in urban development with case study of Semarang city. This study uses an abductive approach by the methodology of case study that armed with a few of theory and has a lot of exploration about the phenomena. The results of this study indicate that the transformation of the smart city concept in Semarang affected by several factors in urban and regional development, which consist of internal and external factors.

Heritage language maintenance through digital tools in young Macedonian children - an exploratory study

ABSTRACT Heritage language maintenance can be very challenging for diaspora communities worldwide. The role of technology on heritage language maintenance has recently started to spark the interest of researchers as a new emerging field but it still needs a lot of exploration. This exploratory study aims to provide an insight into Macedonian diaspora parents’ experiences with digital tools and heritage language maintenance for younger children using a phenomenological approach. Data collected from 23 participants examined the parents’ experience as members of these communities through surveys and follow-up interviews. Results reveal a strong interest in language maintenance, along with challenges such as lack of time and exposure and lack of digital resources for heritage language learning. Participants show a primary interest in using educational apps, emphasizing the need for interactional and engaging resources. Based on these findings, we provide recommendations for developing technology-mediated heritage language maintenance tools.

Discussion on the Current Situation and Countermeasures of Food Hygiene Management in My Country

<p><span lang="EN-US">In recent years, with the frequent occurrence of food safety incidents, all walks of life are paying more and more attention to food safety issues, which effectively promotes the development and optimization of the overall quality of food safety work in my country. On this issue, after a lot of exploration, the researchers pointed out that at this stage, my country’s food hygiene management still has certain shortcomings that need to be improved during the development process. Based on this, a large amount of management work is difficult to be implemented and practiced reasonably, which limits the improvement of the comprehensive level of my country’s food hygiene management work, and has an adverse impact on the development of my country’s food safety work. This article discusses the status quo of the development of food hygiene in my country, and proposes corresponding countermeasures, aiming to promote the optimization of the overall level of hygiene management.</span></p>

Inner Mongolian Cashmere Goat Secondary Follicle Development Regulation Research Based on mRNA-miRNA Co-analysis

Inner Mongolia cashmere goats, as an important part of animal husbandry production, play an important role in animal fiber industry. In recent years, scientific research has made a lot of explorations on the molecular regulation mechanism of hair follicle cycle growth, but few studies have been reported on the development of cashmere hair in fetal period. This study was based on the completion of 21 skin samples of mRNA and miRNA sequencing in 7 fetal periods (45 days, 55 days,65 days,75 days,95 days,115 days and 135 days) of the Inner Mongolia Cashmere goat. The target genes of miRNA associated with the development of secondary hair follicles in the cashmere goats were selected through the combination analysis of mRNA and miRNA data. Then the overexpression vector was constructed and the interaction between the miRNA and the target gene was identified by Dual-Luciferase Reporter Gene System. The function and interaction relationship of chi-miR-199a-5p and TGF-β2 were verified by RT-qPCR and western blot at the level of the fibroblasts in Inner Mongolia Cashmere goat. It provides a theoretical basis for further study of miRNA and its target genes regulating the occurrence and development of skin hair follicles. As the result shows, the expression trends of 7 genes (BAMBI, SMAD1, LTBP1, PPP2R1B, ID4, BMP8B and PITX2) and 7 miRNA (chi-miR-17-5p, chi-miR-125b-3p, chi-miR-21-5p, chi-miR-143-5p and chi-miR-106b-5p) in the skin samples for the seven stages of the fetus were shown to be consistent with the sequencing results. the results of sequencing are reliable. The correlation coefficient of TGF-β2 and chi-miR-199a-5p in fetal 45d-135d expression is −0.84, showing a strong negative correlation, The target relationship was preliminarily judged. The results of double luciferase vector report showed that chi-miR-199a-5p significantly decreased the expression of luciferase in TGF-β2 3′UTR, It is determined that there is a reciprocal relationship between them at a specific time. We transfected chi-miR199a-5p-FAM mimics into fibroblasts cultured in vitro from Inner Mongolia cashmere goats. After transfection, the cells were harvested to extract total RNA and protein. The mRNA and protein expression levels of TGF-β2 in fibroblasts were detected by RT-qPCR and western blot. It was verified that chi-miR-199a-5p inhibited TGF-β2 expression at both mRNA and protein translation levels in fibroblasts. At the same time, it was again proved that the TGF-β2 gene is a target gene of chi-miR199a-5p.

Recent progress of pancreatoduodenectomy: superior mesenteric artery first approach

The incidence of pancreatic cancer showed a clear upward trend in the global range. At present pancreaticoduodenectomy (PD) is still the only possible cure for pancreatic cancer treatment. In order to complete the lymph node dissection as much as possible, increase R0 resection rate after PD, improve long-term efficacy of pancreatic cancer and reduce recurrence, the domestic and foreign scholars have made a lot of exploration and attempt in the scope of surgical resection, resection methods and surgical approach. The superior mesenteric artery as the approach of the PD surgery in the superior mesenteric artery and abdominal cavity to conduct a comprehensive exploration, a reliable and reliable assessment of local vascular invasion and tumor resectability, improve surgical resection, improve the prognosis. The PD with superior mesenteric artery approach could complete a comprehensive exploration on the mesenteric artery and abdominal cavity in surgery, determine the degree of local vascular invasion and tumor resectability reliably, improve the surgical resection rate and improve the prognosis. There are six main methods of clinical use of the superior mesenteric artery(SMA)approach. The author summarizes the surgical methods, related clinical application and research progress of SMA approach in PD in recent years. Key words: Pancreaticoduodenectomy; Artery first approach; Superior mesenteric artery

Reform of Chinese Teaching Mode of Higher Vocational Education Based on Professional Competence

Nowadays with the constant reform of education, higher vocational colleges have also done a lot of exploration in Chinese teaching. We know that the vocational colleges have their particularity of the cultivation of students due to the particularity of their schools. So the education of the school must combine discipline and occupation, and aim at cultivating students' vocational ability. The author analyzes and discusses the present situation of Chinese teaching in higher vocational colleges, and puts forward some measures of how to carry out Chinese teaching with the aim at vocational ability.

Practical Exploration of Inquiry Teaching Method in Chemistry Teaching of Higher Vocational Colleges

Since the concept of quality education is put forward, all colleges and universities has done a lot of exploration on teaching methods, as it is on higher vocational chemistry teaching, inquiry teaching method is one of the many methods of chemistry teaching in higher vocational colleges, its characteristic is to set up the scene and the question in the teaching, induce students to think, determine the way of inquiry finally. After this it also need to experience multiple links, such as hypotheses, tests, results discussion, and so on, through flexible teaching methods, arouse students' interest in chemistry and study enthusiasm to the maximum extent, promote students to learn actively, cultivate the core quality of students, promote the comprehensive development of students' theory and practice, train more comprehensive talents with high quality for the society.

Research on the Cultural Intermediary Organizations in China: Present Developing Situation, Predicament and Improvement Methods

In recent years, the cultural department of our government has been doing a lot of explorations on policy-making, mechanism innovation and market completion, in order to introduce market factors, promote the prosperity and development of cultural industry. As one of the cultural industry market subject, the culture intermediary organizations plays an important role in completing the cultural market operation system, guiding the public cultural products consumption, promoting cultural products trade. The cultural industry developing is indispensable to the standardized operation of cultural intermediary organizations. Integrating the recent years per capita cultural establishment expense, cultural market scale, market business units and the construction of cultural institutions, This paper analyses the current status of the development of cultural industry in China as well as the important factors restricting the development of cultural intermediary organization in our country. Finally, putting forward some Suggestions to promote the development of the cultural intermediary organization in our country from the aspect of perfecting system construction, transforming government functions, building the information sharing platform and establishing cultural talent cultivation mechanism, etc.

A Novel Technique for Shape Feature Extraction Using Content Based Image Retrieval

With the advent of technology and multimedia information, digital images are increasing very quickly. Various techniques are being developed to retrieve/search digital information or data contained in the image. Traditional Text Based Image Retrieval System is not plentiful. Since it is time consuming as it require manual image annotation. Also, the image annotation differs with different peoples. An alternate to this is Content Based Image Retrieval (CBIR) system. It retrieves/search for image using its contents rather the text, keywords etc. A lot of exploration has been compassed in the range of Content Based Image Retrieval (CBIR) with various feature extraction techniques. Shape is a significant image feature as it reflects the human perception. Moreover, Shape is quite simple to use by the user to define object in an image as compared to other features such as Color, texture etc. Over and above, if applied alone, no descriptor will give fruitful results. Further, by combining it with an improved classifier, one can use the positive features of both the descriptor and classifier. So, a tryout will be made to establish an algorithm for accurate feature (Shape) extraction in Content Based Image Retrieval (CBIR). The main objectives of this project are: (a) To propose an algorithm for shape feature extraction using CBIR, (b) To evaluate the performance of proposed algorithm and (c To compare the proposed algorithm with state of art techniques.

V-MIN: Efficient Reinforcement Learning through Demonstrations and Relaxed Reward Demands

Reinforcement learning (RL) is a common paradigm for learning tasks in robotics. However, a lot of exploration is usually required, making RL too slow for high-level tasks. We present V-MIN, an algorithm that integrates teacher demonstrations with RL to learn complex tasks faster. The algorithm combines active demonstration requests and autonomous exploration to find policies yielding rewards higher than a given threshold Vmin. This threshold sets the degree of quality with which the robot is expected to complete the task, thus allowing the user to either opt for very good policies that require many learning experiences, or to be more permissive with sub-optimal policies that are easier to learn. The threshold can also be increased online to force the system to improve its policies until the desired behavior is obtained. Furthermore, the algorithm generalizes previously learned knowledge, adapting well to changes. The performance of V-MIN has been validated through experimentation, including domains from the international planning competition. Our approach achieves the desired behavior where previous algorithms failed.

Study on Various Methodologies/frameworks used to Achieve Software Quality in different Organizations

Purpose of this study is to explain that how the various methodologies, frameworks and processes leads to software quality. Numerous methodologies have been introduced on which lot of exploration or research has been made. This paper includes the study of some processes and techniques which have been used by the firms to achieve software quality. This study strongly recommends the necessity of consciousness regarding the use of software quality oriented processes and the arenas on which extra work leads to quality of software or quality assurance.

Experimental Study on Reflective Optical Fiber Hydrogen Sensor Using Two-Wavelength Light Sources

Nowadays, optical fiber hydrogen sensor is one of most important potential of optical fiber sensors. Currently, there are a lot of explorations around this aspect. This paper uses experimental method to study reflective optical fiber hydrogen sensor with two-wavelength light sources. Firstly, the experimental principle was introduced. Based on the principle, experimental scheme, devices, and process are described. By the experiment, the reflectance is the output as the main result. The experiment results describes at last.