Abstract Aim Solid organ transplantation (SOT) is rising, with improvements in surgical technique and immunosuppressive therapy increasing patient survival. Age-related degeneration and long-term steroid therapy in SOT recipients lead to higher incidence of osteoarthritis and osteonecrosis. Total hip arthroplasty (THA) is offered electively for these indications. This meta-analysis assessed THA-related complications in SOT versus non-SOT recipients, reporting revision, infection rates, and all-cause mortality. Method This review was carried out using the PRISMA framework. A literature search of Medline, Embase, Transplant library, and Cochrane Library was carried out. Full text articles were screened. Summary statistics for outcomes of interest underwent meta-analyses to a confidence interval (CI) of 95% and are presented as Forest plots for Odds Ratio (OR). Results Literature search returned 1164 unique titles/s. 36 met inclusion criteria; 6 were retrospective cohort-studies. Meta-analysis of 5 studies showed no evidence of significant increase in revision rates with prior SOT, OR=0.67 (95%CI: 0.36-1.23, p=0.19). Meta-analysis of 6 studies showed no significant increase in infection (joint/surgical site) infection with prior SOT, OR=1.18 (95%CI: 0.40-3.50, p=0.77). Meta-analysis of 3 studies showed significant increase in all-cause mortality over 12 months post-arthroplasty, OR=1.99 (95%CI: 0.99-3.99, p=0.05). We report these summary statistics for the remaining case series. Conclusions We conclude that there is no significant increase in revision and infection rates for THA in SOT recipients. Consideration of a significant increase in all-cause mortality must be noted prior to offering this procedure to SOT recipients. Prospective studies are needed to assess risks/benefits of THA in SOT recipients.