Long-term Rhythms Research Articles

Gender and age-specific patterns of ambulance calls in Khanty-Mansiysk depending on the epidemiological situation

BACKGROUND: The number of ambulance calls serves as an objective indicator of the disruption in population health associated with maladaptation or an increase in health disorders in harsh conditions of the North. This becomes especially apparent when the epidemiological situation shifts, highlighting the importance of this issue. AIM: To study the gender- and age-specific patterns of emergency calls for ambulance services in the population of Khanty-Mansiysk during varying epidemiological conditions using long-term monitoring data. MATERIAL AND METHODS: Data on daily counts of ambulance calls was obtained from the for the period from 2015 to 2021 stratified by age and gender. The data were analyzed using wavelet analysis. RESULTS: When analyzing gender disparities during a pandemic, the coefficient representing the ratio of calls made by women to men decreased as the number of calls made by men increased. The distribution of calls by age revealed two distinct risk groups: young children and older adults. During the pandemic, there were no significant qualitative changes in the distribution of calls. Several scenarios of desynchronosis induced by the COVID-19 pandemic were identified. In infants, the changes in the epidemiological situation did not affect constant rhythms. The changes in the constant circadian rhythms to long-term and intercalary intra-annual rhythms were observed among children and youth. In adolescents and young adults, the pandemic acted as a synchronizer. In older age-groups, the circadian rhythms were maintained throughout the entire period. The period of the pandemic was characterized by addition of rhythms with a shorter period. CONCLUSION: The distribution of ambulance calls across age-groups is characterized by the presence of two distinct risk groups — early childhood and the 2nd adult age. During the pandemic, the structure of calls did not demonstrate qualitative changes. The COVID-19 pandemic was a desynchronizing factor in the temporal structure of health disorders affecting long-term and near-annual rhythms and inducing the intercalary intra-annual rhythms.

Corrections for geographical differences in photoperiod in time-series analysis

This article presents the results of the development of the corrections for geographical differences and photoperiodism in time-series analyses of physiological and demographic indicators.
 the models were created using the results of the studies of biological rhythms obtained using the software developed by the author using wavelet analysis and photoperiodic stability of the chronotype during adaptation to the conditions of the North, shift work in healthy individuals as well as in subjects with somatic or mental pathology. We also assessed long-term demographic rhythms of the population living in different regions of Russia.
 For standardization and ranking of interseasonal, inter-regional studies (physiology of movements and shift work) in chronophysiological format, we propose the use of the calculated "photoperiodic latitudinal coefficient". To improve the accuracy of the models, we propose the use of the "signal- noise coefficient" in the interpretation of the results, an assessment of the "degree of polyrhythmicity" and the "rhythm instability index" in the presence of "inserted" or "quantized" rhythms.

Impact of the temperature factor on the quality of road clothes

The article deals with the problems of designing roads associated with short-term and relatively long-term rhythms of temperature fluctuations. The results of temperature changes in the long-term cycle in the Jizzakh region of Uzbekistan are presented. Based on the importance of the temperature factor, measures to prevent the process of destruction of asphalt concrete road surfaces are recommended.

Variability of Helioclimate Factors and Applicability to the Emergency Service Population of the Northern Region

The purpose of this study was to study the influence of the variability of weather and heliophysical factors on the appeal to the Ambulance service for different groups of nosologies in the population of the Russian North. Information about calls to the emergency medical service of Khanty-Mansiysk was obtained from the database of calls for the period from 2001 to 2021 by disease classes (ICD-10). To assess the dynamics of weather factors, data from the All-Russian Research Institute of Hydrometeorological Information and materials from the weather station of Khanty-Mansiysk were used. The dynamics of air temperature; barometric pressure; relative humidity; baric trend; maximum wind speed; weight oxygen content in the air are analyzed. Data on the relative daily number of sunspots are obtained from the materials of the Royal Observatory of Belgium. The average daily values of the level of planetary geomagnetic activity, expressed by the Ap index, are copied from the website of the National Center for Geophysical Data of the USA (Boulder). Mathematical processing was carried out using wavelet analysis. The graph of temperature fluctuations for the period from 2001 to 2021 shows a significant circadian cyclicity and a semi-annual rhythm with a high level of trend. Significant rhythms of barometric pressure with a period of 5 years, 1 year and rhythms close to semi-annual, seasonal and near-monthly are observed. Humidity changes significantly in the circadian and intra-annual rhythms. The baric tendency has significant rhythms: 3 years, 1 year, 6, 3, 2 months. Changes in the maximum wind speed do not have a circadian rhythm, but intra-annual monthly variations are observed. The value of the weight oxygen content has circadian; two-year, five-year; two- and near-monthly rhythms. The relative number of sunspots (W) for the period from 2001 to 2021 is characterized by a five-, two-year and circadian rhythm. When considering the variations of the number W for the period from 1818 to 2017, in addition to the classic eleven-year, annual and near-monthly, rhythms with a period of 42.5 years, 18.1 years and 2.1 years are found. The index of planetary geomagnetic activity (Ar) has a rhythm with a period of 4 years, two-year and near-annual. The significance of all rhythms is p=0.001. When analyzing fluctuations in geomagnetic activity from 1932 to 2016, long-term rhythms are added: 35.00 years; 16.06 years; 10.88 years; semi-annual and three-month rhythms. Despite numerous hypotheses of the search for cosmobiological harmony in the form of evolutionary synchronisms, rhythmic cascades, golden section, the problem of the interaction of exogenous natural rhythms and endogenous rhythms of the human body remains largely unresolved. Comparison of the results of various studies is difficult due to methodological and mathematical approaches. With observation periods of 100-200 years or more, a long-period component is monitored, and in clinical studies (from a day to a week), short-period components are detected. Changing the background in the form of helioclimatic and social variations also does not add accuracy. The use of various methods of time series analysis involves obtaining information of different resolution levels (Fourier transform, SWANN, wavelet analysis). Nevertheless, the results obtained track the classical rhythms of solar and geomagnetic activity with periods of about eleven years, a year and a month. There is also a 35-year-old rhythm, a 42.5-year-old rhythm close to the 44.16-year rhythm identified by Bezrukova A.Ya., at 18.1 years (long-period components of the lunar tide) and other intra-annual rhythms with periods from two weeks to 9 months. The effect of helioclimatic factors on human health indicates the absence of constant coherence (in our case, the consistency of these processes over time, manifested when they are combined), due to the presence of a large number of mega- and mesorhythms, which is manifested by amplitude and phase desynchronization of heliogeophysical indicators and health status.

Seasonality of prolactin in birds and mammals.

In most animals, annual rhythms in environmental cues and internal programs regulate seasonal physiology and behavior. Prolactin, an evolutionarily ancient hormone, serves as a molecular correlate of seasonal timing in most species. Prolactin is highly pleiotropic with a wide variety of well-documented physiological effects; in a seasonal context prolactin is known to regulate annual changes in pelage and molt. While short-term homeostatic variation of prolactin secretion is under the control of the hypothalamus, long-term seasonal rhythms of prolactin are programmed by endogenous timers that reside in the pituitary gland. The molecular basis of these rhythms is generally understood to be melatonin dependent in mammals. Prolactin rhythmicity persists for several years in many species, in the absence of hypothalamic signaling. Such evidence in mammals has supported the hypothesis that seasonal rhythms in prolactin derive from an endogenous timer within the pituitary gland that is entrained by external photoperiod. In this review, we describe the conserved nature of prolactin signaling in birds and mammals and highlight its role in regulating multiple diverse physiological systems. The review will cover the current understanding of the molecular control of prolactin seasonality and propose a mechanism by which long-term rhythms may be generated in amniotes.

Exercise improves long-term social and behavioral rhythms in older adults: Did it play a role during the COVID-19 lockdown?

The study aimed to verify whether exercise training in older adults can improve social behavioral rhythms (SBR) and if any modification is maintained over time. Older adults (n=120) from a previous randomized controlled trial (RCT), were randomly allocated to either a moderate-intensity exercise group or a control group. SBR was evaluated at t0, t26, and t48 weeks (during the COVID-19 lockdown), using the brief social rhythms scale (BSRS). Seventy-nine participants completed the follow-up (age 72.3±4.7, women 55.3%). An improvement in the BSRS score was found in the exercise group at 26 weeks (p=0.035) when the exercise program was concluded, and it was still maintained at 48 weeks (p=0.013). No improvements were observed in the control group. To conclude, social behavioral rhythms (SBR), previously found as a resilience factor in older adults during Covid-19, appear to improve after a moderate 12 weeks exercise program, and the improvement persisted even after stopping exercise during the COVID-19 lockdown. Significance for public health The pandemic condition, requiring community containment and social distancing has widely affected the population, especially older adults. However, improvement of social and behavioral rhythms (SBR) in the year before the Covid-19 lockdown were found as an important resilience factor, especially against the risk of depression. Current study suggests that a moderate 12 weeks exercise program improved SBR and that the benefits persisted even after stopping exercise during the COVID-19 lockdown.

The rhythms of rhythm

The low frequency (LF) spectral analysis or ‘rhythm spectrum’ approach to the quantitative analysis and comparison of speech rhythms is extended beyond syllable or word rhythms to ‘rhetorical rhythms’ in read-aloud narratives, in a selection of exploratory scenarios, with the aim of developing a unified theory of speech rhythms. Current methodologies in the field are first discussed, then the choice of data is motivated and themodulation-theoreticrhythm spectrum and rhythm spectrogram approach is applied to the amplitude modulation (AM) and frequency modulation (FM) of speech. New concepts ofrhythm formant,rhythm spectrogramandrhythm formant trajectoryare introduced in theRhythm Formant Theory(RFT) framework with its associated methodologyRhythm Formant Analysis(RFA) in order to capture second order regularities in the temporal variation of rhythms. The interaction of AM and FM rhythm factors is explored, contrasting English with Mandarin Chinese. The LF rhythm spectrogram is introduced in order to recover temporal information about long-term rhythms, and to investigate the configurative function of rhythm. The trajectory of highest magnitude frequencies through the component spectra of the LF spectrogram is extracted and applied in classifying readings in different languages and individual speaking styles using distance-based hierarchical clustering, and the existence of long-term second order ‘rhythms of rhythm’ in long narratives is shown. In the conclusion, pointers are given to the extension of this exploratory RFT rhythm approach for future quantitative confirmatory investigations.

Многолетние демографические ритмы коренного и пришлого населения ХМАО – Югры

Многолетние демографические ритмы коренного и пришлого населения ХМАО – Югры

Estrone exposure interacts with temperature to alter predator evasion performance and systemic mRNA abundances

Environmental estrogens from anthropogenic activities are ubiquitous in aquatic ecosystems. Ambient temperature in these systems also fluctuates in daily, seasonal, and long-term rhythms. While both factors have been studied extensively, their interaction on aquatic life is critical to understand. The objective of this study was, therefore, to examine how behavior and gene expression are impacted by estrogenic exposure across a range of environmental temperatures. Larval fathead minnows (Pimephales promelas) were exposed to estrone (E1) at two concentrations (nominal 625 and 1250 ng/L) or to an ethanol solvent control, at one of four temperatures (15, 18, 21 and 24 °C) from fertilization to 21 days post-hatch. Exposed larvae were assessed for alterations in predator evasion performance and mRNA abundances of two genes for calcium channel receptors found in muscles - dihydropyridine receptor (dhpr) and ryanodine receptor 1, and the gonadal genes anti-Müllerian hormone, cytochrome P450 gonadal aromatase (cyp19a), doublesex and mab-3 related transcription factor 1 (dmrt1) and estrogen receptor 1 (esr1). Larval escape angle, escape latency, as well as systemic esr1 and cyp19a mRNA abundances were altered by an interaction between E1 concentration and temperature. E1-exposed larval exhibited reduced escape performance across all tested temperatures, whereas decreased systemic dhpr mRNA abundance was observed only at 18 °C. E1-exposure reduced systemic mRNA abundances of amh, cyp19a, dhpr, and ryr1, while temperature significantly reduced systemic cyp19a and dhpr mRNA abundances. E1-exposure and temperature significant enhanced systemic mRNA abundances of esr1 and cyp19a, respectively. These complex results illustrate the importance of considering how abiotic factors may moderate the effects of contaminant exposure during the sensitive larval developmental stage, as temperature modulates effects of estrogenic exposure on animal performance and mRNA abundances.

A brief history of circannual time.

Innate circannual timing is an ancestral trait that first evolved in free-living eukaryotic cells some 2000million years ago, with marine algae of the genus Allexandrium providing a living unicellular model. This species shows the primitive trait of 'alternation of generations', where the organism alternates between fast replicating vegetative cells in the summer and a dormant cystic cell over the winter. The resistant cysts sink into the cold ocean sediments. Remarkably, excystment in spring is governed by an endogenous circannual timing mechanism. Thus, a tiny, short-lived unicell can utilise a circannual clock as part of the life-history programme of the species. Innate timing allows for major adjustments in physiology and behaviour in anticipation of the seasons, and provides an internalised sense of seasonal time for the many species where standard environmental cues are weak or ambiguous. This is a highly adaptive strategy irrespective of the size and longevity of an organism. Circannual rhythms are expressed by a diverse range of organisms, from flowering plants to mammals, interwoven into the life-history programme of each species, being a consequence of forever living in a periodic world. In complex vertebrates, the early division of the zygote potentially carries circannual timer genes into all progeny cells and tissues. This supports the concept of a 'clock-shop' where cell-autonomous long-term rhythms are generated in each tissue, orchestrated by a central circannual pacemaker system. This is analogous to the organisation of the circadian timing system. For the circannual time-scale, specialised thyrotroph cells located in the pars tuberalis of the pituitary gland and adjacent tanycyte cells located in the ependymal wall of the third cerebral ventricle of the brain act as putative central circannual pacemakers. At a molecular level, epigenetically regulated, cyclical remodelling of chromatin, which determines whether specific circannual timer genes are transcriptionally active, or not, is considered to drive the oscillation between the summer and winter phenotypes.

Investigation of the Class of One-Dimensional Unimodal Mappings Obtained in the Modeling of the Lemming Population

A model that describes periodic changes in the lemming population size as a function of the physical characteristics of ecologically significant parameters of the habitat is analyzed. Earlier studies on modeling of the population size dynamics for tundra animals substantiated a new class of one-dimensional unimodal mappings of a state space into itself. The dependence of trajectory stability on parameter variation and the bifurcation and asymptotic properties of the trajectories are in the focus of attention when this class of mappings is studied. Methods for approximating implicitly defined sets are used for numerical analysis of the maps: trajectory tubes, attractors, and bifurcation diagrams are constructed. An example of a bifurcation diagram construction along the contour in the parameter space is given for this class of mappings; the diagram enables the analysis of the dependence of trajectory behavior on changes of the modeling map parameters. Thus, the use of the mapping of the type considered for the model description of the lemming population enabled the study of the effect of long-term biospheric rhythms, which include time intervals with extreme living conditions. The study showed that such impacts do not cause degeneration of the population: the periods with chaotic dynamics that emerge under extreme conditions are replaced by well-ordered behavior in the form of small-period population cycles.

Shifts in the light-dark cycle increase unpredictability of the cardiovascular system.

Physiological variables such as heart rate (HR) and blood pressure (BP) exhibit long-term circadian rhythms, which can be disturbed by shift work. On the other hand, short-term oscillations in HR and BP have a high prognostic value. Therefore, we aimed to determine if the short-term variability, complexity and entropy of HR and BP would be affected by a regular light/dark (LD) cycle and phase delay shifts of the LD cycle, leading to chronodisruption. Telemetry-monitored rats were exposed first to the regular LD cycle and then to shifts in LD for 8weeks. On the basis of long-term HR and BP recording and evaluation, we found circadian rhythms in HR and BP variability, complexity and entropy under regular LD cycles. Short-term exposure to shifts disturbed circadian rhythms of HR and BP variability, complexity and entropy, indicating chronodisruption. The power of circadian rhythms was suppressed after 8weeks of phase delay shifts. Long-term exposure to shifts increased variability (p=0.007), complexity (p<0.001) and dark-time entropy (p=0.006) of HR but not BP. This is the first study demonstrating long-term recording and estimation of HR and BP variability, complexity and entropy in conscious rats exposed to irregular lighting conditions. After long-term phase delay shifts, short-term variability of HR was less predictable than in controls. This study suggests that changes in short-term HR and BP oscillations induced by long-term shift work can negatively affect cardiovascular health.

Physiological performance of the intertidal Manila clam (Ruditapes philippinarum) to long-term daily rhythms of air exposure

Intertidal organisms, especially the sessile species, often experience long-term periodic air exposure during their lives. Learning the biochemical and physiological responses of intertidal organisms to long-term periodic air exposure and the relationship to duration of air exposure provides insight into adaptation to this variably stressful environment. We studied the Manila clam, Ruditapes philippinarum, an important species in world aquaculture, as a model to evaluate survival, growth, lipid composition, oxygen consumption, oxidative damage, and antioxidant enzyme activity in relation to the duration of air exposure in a long-term (60 days) laboratory study of varying durations of periodic emersion and re-immersion. Our results show: (1) clams undergoing a longer period of air exposure had lower survival and growth compared to those given a shorter exposure, (2) levels of oxidative damage and activities of antioxidant enzymes were higher in all air exposure treatments, but did not increase with duration of air exposure, and (3) the content of docosahexaenoic acid increased with duration of air exposure. Our results can largely be interpreted in the context of the energy expenditure by the clams caused by aerobic metabolism during the daily cycle of emersion and re-immersion and the roles of docosahexaenoic acid against oxidative stress.

Long-term rhythms in the development of Hawaiian social stratification

The tempo plot, a statistical graphic designed for the archaeological study of rhythms of the long term that embodies a theory of archaeological evidence for the occurrence of events, is introduced. The graphic summarizes the tempo of change in the occurrence of archaeological events using the model states generated by the Markov Chain Monte Carlo routine at the heart of Bayesian calibration software. Tempo plots are applied to the archaeological record of Hawai‘i to expose rhythms of i) tradition in taro pond-field construction, ii) innovation in temple construction, and iii) fashion in the harvest of branch coral for use as a religious offering. Rhythms of the long term identify a hitherto unrecognized transformation of religious practice in Hawai‘i, establish temporal coincidence in temple construction in leeward sections of Maui and Hawai‘i Islands previously described as regionally idiosyncratic, suggest shallow temporal limits to the use of the direct historical approach in Hawai‘i, and disclose processes at work in the political economy recorded at the time of western Contact.

Economic Crises and the Shape of Modern History

Inspired by the current world economic crisis, this article attempts to assess the place of economic crises in the longer history of capitalism. Combining perspectives from Karl Marx, Joseph A. Schumpeter, Hyman Minsky, and Giovanni Arrighi, the article moves from crises to the business cycles of which they are a product, to the long-term rhythms of capitalist development. It concludes by looking at the current crisis from the point of view of these longer rhythms.

Introduction. Editorial on ‘Signal processing in vital rhythms and signs’

Signal processing has become a core technology in medical devices today, as it is crucial in a wide range of applications. It is used to automate the measurement of various signal characteristics, which previously was done manually and, as a result, subjectivity is reduced and reliability is increased. Another purpose is to filter out undesired signal components of technical or physiological origin so that the signalto-noise ratio is improved and subsequent analysis facilitated. Signal processing is also of key importance when uncovering components with low amplitude and/or subtle variations in frequency, which are very difficult, if not impossible, to observe by the naked eye. For example, signal processing plays a crucial role for the detection of the alternans phenomenon occurring during cardiac repolarization. Information about alternans has turned out to be the most useful for risk stratification of certain cardiac patients. The analysis of heart rate variability represents another application where signal processing is essential for the characterization of tiny oscillations in rhythm; the resulting measurements convey unique information about the autonomic nervous system. Considering that today’s recording equipment and computers are quite powerful and available at affordable prices, limitations related to implementation are rather procedural than computational. The role of signal processing can therefore be expected to further increase in the future as novel techniques are developed and used to uncover and characterize hidden activity which may be present in a signal. Traditionally, biomedical signal processing has been largely synonymous to ‘unimodal’ analysis in which only one type of signal has been subjected to analysis at a time. Countless approaches have been developed to unimodal analysis of the most common bioelectrical signals, i.e. the electrocardiogram (ECG), the electroencephalogram (EEG) and the electromyogram (EMG). However, multimodal signal modelling and processing are currently receiving considerable attention as it is highly desirable to account for the interdependence that exists between different

Fluctuations in the momentum of growth within the capitalist epoch

This paper reviews the history of cyclical and long wave analysis and examines the evidence on changes in the momentum of economic growth in 16 advanced capitalist countries from 1820 to 2001. It assesses the work of the main Business Cycle Research Institutes in Western Europe the USA and Russia, as well as that of Kondratieff, Kuznets, Schumpeter, Abramovitz and the long-wave revivalists-Rostow, Mandel and Mensch. It concludes that the existence of regular long-term rhythms in capitalist development is not proven, but distinguishes major changes in the momentum of growth due to disturbances of an ad hoc character. The role of system shocks and historical accidents is important but the role of policy error and success is also emphasised. It identifies five major phases of capitalist development since 1820.

Long-term pedolithogenic rhythms in the Holocene

Soil-sedimentary series in subordinate (accumulative and trans-accumulative) landscapes represent the most complete and detailed record of the development of soils, topographic forms, and local geosystems in the Holocene. A new conception of centuries-long rhythms of soil formation and erosion is offered on the basis of literature analysis and original data on 80 pits within the East European Plain supplied with 180 radiocarbon dates. It is established that the Holocene (the last 10 500 years) comprises seven stages of soil formation alternating with stages of intensive erosion and sediment accumulation: 450–950, 2300–2700, 4200–4700, 6300–6600, 7700–8100, 9500–10 200 BP. The intervals of 450–150, 1050–2300, 2800–4200, 4700–6200, 6600–7700, 8300–9500, and 10 200–10 400 BP correspond to the formation of soils in the geochemically subordinate (footslopes, gully bottoms, floodplains) landscapes. The erosion–lithogenetic stages are characterized by humid warm and cold and also arid cold climatic conditions. The pedogenetic stages in subordinate landscapes of the forest-steppe and forest zones fall mainly into arid warm and, sometimes, humid warm and arid cold climatic phases of the 2000-year-long rhythm known as the Shnitnikov rhythm.

The consolations of ‘neoliberalism’

Recent work on neoliberalism has sought to reconcile a Marxist understanding of hegemony with poststructuralist ideas of discourse and governmentality derived from Foucault. This paper argues that this convergence cannot resolve the limitations of Marxist theories of contemporary socio-economic change, and nor do they do justice to the degree to which Foucault’s work might be thought of as a supplement to liberal political thought. The turn to Foucault highlights the difficulty that theories of hegemony have in accounting for the suturing together of top-down programmes with the activities of everyday life. However, the prevalent interpretation of governmentality only compounds this problem, by supposing that the implied subject-effects of programmes of rule are either automatically realised, or more or less successfully ‘contested’ and ‘resisted’. Theories of hegemony and of governmentality both assume that subject-formation works through a circular process of recognition and subjection. Both approaches therefore treat ‘the social’ as a residual effect of hegemonic projects and/or governmental rationalities. This means that neither approach can acknowledge the proactive role that long-term rhythms of socio-cultural change can play in reshaping formal practices of politics, policy, and administration. The instrumental use of notions of governmentality to sustain theories of neoliberalism and neoliberalization supports a two-dimensional understanding of political power—which is understood in terms of relations of imposition and resistance—and of geographical space—which is understood in terms of the diffusion and contingent combination of hegemonic projects. Theories of neoliberalism provide a consoling image of how the world works, and in their simplistic reiteration of the idea that liberalism privileges the market and individual self-interest, they provide little assistance in thinking about how best to balance equally compelling imperatives to respect pluralistic difference and enable effective collective action.

真性粘菌変形体の移動における長周期リズム

真性粘菌変形体の移動における長周期リズム