ObjectivesTo examine the associations of a combination of urinary incontinence (UI) and life-space activity/mobility with the risk of incident disability among community-dwelling older adults. Study designThe participants were 12,808 older adults for the cross-sectional study and 12,516 older adults who completed the follow-up assessment. Main outcome measuresUI was assessed using a questionnaire. Life-space activity/mobility was evaluated using total, physical, and social scores on the Active Mobility Index (AMI). Participants were classified into four groups (high AMI total score + no UI; high AMI total score + UI; low AMI total score + no UI; low AMI total score + UI). Incident disability was extracted from the Japanese Long-Term Care System. ResultsDuring the 24-month follow-up, 562 participants (4.5 %) developed disability. Those with a low AMI score + no UI (hazard ratio, 1.35; 95 % confidence interval, 1.07–1.71) and those with a low AMI score + UI (hazard ratio, 2.00; 95 % confidence interval, 1.56–2.56) had a higher risk of incident disability than those with a high AMI score + no UI in the follow-up analysis. ConclusionsA combination of UI and low AMI score was associated with an increased risk of incident disability, whereas having UI but a high AMI score was not associated with an increased risk of incident disability. Our findings may help identify older adults at high risk of developing disabilities.