Skin diseases are not only a health problem, but also a significant psychological and social trouble affecting every age group of patients. One of the largest groups of skin diseases are mycoses including mycoses of the skin and its appendages. The most common symptoms of infection are skin itching and burning, followed by disruption at the stratum corneum. Treatment includes the use of natural antibiotics such as griseofulvin and synthetic derivatives such as terbinafine. Chronic skin disease, which includes mycosis, necessitates taking medications for a long time, which translates into reduced effectiveness of the drug and side effects. The latest results of study herbal substances prove that they exhibit high fungistatic and fungicidal activity. Therefore, medicinal plants and their secondary metabolites are increasingly used in antifungal therapy. Essential oils are one of the products of secondary metabolism of plants. With the right dosage, they can be used for a long time with eliminating the risk of side effects. So far have been no reports of the increasing resistance of bacterial or fungal strains to the components of essential oils, which often occur in the case of long-term antibiotic therapy. The paper describes essential oils of tea tree, thyme, oregano, basil, sage, savory, clove and cinnamon, showing the greatest effectiveness in the antifungal therapy of the skin and its appendages.