Local Deposits Research Articles

High frequency of occult transthyretin and apolipoprotein AI–type amyloid in aortic valves removed by valve replacement for aortic stenosis

Background A high incidence of valvular involvement of amyloid in the setting of aortic stenosis (AS) has been reported. Amyloid derived from ApoAI (AApoAI) can form local amyloid deposits in the aortic valve. Although a high prevalence of concomitant severe AS and cardiac transthyretin-type amyloidosis (ATTR) has been reported, the prevalence of valvular involvement by ATTR and AApoAI is unclear. Methods Using immunostaining and mass spectrometry, we analysed amyloid proteins in 97 aortic valves removed for valve replacement due to AS at Kyoto Prefectural University of Medicine between 2014 and 2021. Clinical information was also reviewed. Results Amyloid deposits were found in 44 cases (45%), of which 30 cases (68%) involved ATTR and 33 cases (75%) AApoAI. Statistical analysis showed significantly lower age and E/e′ among amyloid-positive cases compared with amyloid-negative cases and significantly lower brain natriuretic peptide, higher fractional shortening, and higher left ventricular ejection fraction among ATTR-positive cases compared with ATTR-negative cases. Seven recent patients underwent bone scintigraphy and ATTR cardiomyopathy was observed in only one case. Conclusions AS symptoms can manifest earlier in patients with amyloid or ATTR deposition in the aortic valve than in patients without such deposition, even though left ventricular function is preserved.

The Relationship Between Perimesenteric Fat and Measures of Central Adiposity in Young Adults.

Visceral fat has been identified as a key contributor to metabolic disorders owing to its association with decreased adipocytokine function. Perivascular adipose tissue (PVAT), a specialized local deposit of adipose tissue surrounding arteries, has been shown to regulate vascular tone through adipocytokine functionsbut is compromised in obesity, contributing to increased vascular resistance. This study aimed to investigate the correlation between PVAT of the superior mesenteric artery (SMA), visceral adipose tissue (VAT), body mass index (BMI), and waist-to-hip ratio (WHR). WHR and BMI were anthropometric measurements used to assess body composition. A GE LOGIQ ultrasound system with a 12 MHz abdominal probe transducer was used to measure VAT at the SMA, VAT at the umbilicus, and PVAT of SMA in 31 healthy participants, male and female, aged 18-30. Pearson's correlation matrix was generated to assess the strength of the correlation between variables, and ANOVA was used to assess the statistical significance of Pearson's correlation coefficient (r) values. PVAT positively correlated with BMI, WHR, and VAT (p<0.05). Interestingly, PVAT was more strongly correlated with BMI than with WHR and should be considered when evaluating PVAT if ultrasound is not available. Perimesenteric fat is also associated with adiposity. Further investigation is required to assess the associations between PVAT of other named arteries with measures of adiposity in older adults and patients with cardiovascular disease (CVD). In addition, given the vascular dysfunction associated with excess PVAT, correlations with factors such as blood flow and pressure should be considered.

Advances in estimations of number of undiscovered mineral deposits in three-part assessments

A central part of three-part mineral assessments is estimating number of undiscovered mineral deposits. Internal consistency and well-explored deposits in grade–tonnage models reduce chances of biased estimates in three-part quantitative assessments. Estimates are of specific types of deposit permitted by geology in delineated tracts. Regardless of estimation method, each deposit type needs a grade–tonnage model constructed with well-explored deposits and estimated numbers must be consistent with this model. Local well-explored deposits are typed and statistically tested to ensure the global grade and tonnage model is representative of them.Three-part assessments used expert judgements since 1975 that relied on analogy-based guidelines to aid in estimation of number. The advantage of expert judgements is that they can use all available information and adapt to information supplied by other experts during the assessment. A targeting method has seen limited application due to the requirement that location indicators of each possible target need to be present. Another estimation method developed around 2008 is a generalized deposit density model based on multiple deposit types which uses deposit type's median tonnage, permissive tract area, and number of known deposits in well-explored control areas. It is remarkably robust and can be applied to any deposit type in a proper permissive tract.Advanced deposit estimations use the generalized density method to guide expert estimates. Experts can then identify possibly flawed estimates and improve estimates based on local information such as local exploration results or observations by experts thereby further reducing chances of biased estimates.

Metabolic Effects of Liposuction on Glucose and Insulin Homeostasis with and Without Abdominal Fat Removal.

Liposuction is a common cosmetic procedure aimed at addressing localized fat deposits. While metabolic disruptions associated with adiposity are well documented, the specific impacts of liposuction on metabolic parameters remain unclear. Seventeen individuals underwent liposuction inclusive of the abdominal area, while eleven underwent liposuction excluding the abdomen. Metabolic parameters including glucose, insulin, HOMA-IR, HbA1c, and C-peptide levels were measured preoperatively and postoperatively at 1, 3, and 6 months. Both groups exhibited significant postoperative reductions in glucose, insulin, HOMA-IR, HbA1c, and C-peptide levels. However, the abdominal liposuction group demonstrated more pronounced reductions of these variables. These findings suggest that addressing abdominal adiposity may provide greater metabolic benefits following liposuction. Further research is warranted to explore the long-term sustainability and clinical implications of these metabolic improvements with additional markers. This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.

Extraction of Aluminum Oxide from Local Kaolin Clay Deposits in Ethiopia

The need for aluminum is growing worldwide, which has sparked interest in finding alternate ways to make alumina from materials other than bauxite, particularly clays. This article examines the use of sodium carbonate as a leaching agent in the lime sintering process to recover alumina from kaolin. Excavated from Tarmaber, Ethiopia, kaolin clay contains a content of 32.88%, which has a relatively good composition. Collecting and grounding raw kaolin to micrometer-level particle size is the first task. The recovery of kaolin alumina was studied at sintering temperatures of (T&amp;lt;sub&amp;gt;1&amp;lt;/sub&amp;gt;=800°C, T&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;= 900°C &amp; T&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;=1000°C) at different sintering times of (t&amp;lt;sub&amp;gt;1&amp;lt;/sub&amp;gt;=1 hr, t&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;=2 hrs &amp; t&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;=3 hrs). After the raw material was burned at the given temperatures and times, it was cooled for the night in the furnace and leached with different concentrations of sodium carbonate (M&amp;lt;sub&amp;gt;1&amp;lt;/sub&amp;gt;=50 g/l, M&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;=60 g/l &amp; M&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt;=70 g/l). The response surface methodology (RSM) in combination with the central composite design was used to optimize the operating parameters. The optimization result shows that the optimal conditions were a calcination temperature of 953.84°C, a sintering time of 2.99 h, and a leaching agent concentration of 70 g/l. At this optimal condition, the yield of Alumina was 1.05 g of 20 g of Kaolin clay. The resulting Alumina was crystalline in structure (from XRD analysis), contains 89.05% Al&amp;lt;sub&amp;gt;2&amp;lt;/sub&amp;gt;O&amp;lt;sub&amp;gt;3&amp;lt;/sub&amp;gt; (from silicate analysis) and a large broad band between 400-1000 cm&amp;lt;sup&amp;gt;-1&amp;lt;/sup&amp;gt; is attributed to Al-O-Al stretching of Alumina (from FT-IR analysis). So, it is possible to conclude that alumina production from no bauxite ores is possible.

Acetyl-CoA carboxylase inhibition increases retinal pigment epithelial cell fatty acid flux and restricts apolipoprotein efflux

Lipid-rich deposits called drusen accumulate under the retinal pigment epithelium (RPE) in the eyes of patients with age-related macular degeneration (AMD) and Sorsby’s fundus dystrophy (SFD). Drusen may contribute to photoreceptor and RPE degeneration in these blinding diseases. We hypothesize that stimulating β-oxidation of fatty acids could decrease the availability of lipid with which RPE cells can generate drusen. Inhibitors of acetyl-CoA carboxylase (ACC) stimulate β-oxidation and diminish lipid accumulation in fatty liver disease. In this report we test the hypothesis that an ACC inhibitor, Firsocostat, can diminish lipid deposition by RPE cells. We probed metabolism and cellular function in mouse RPE-choroid tissue and in cultured human RPE cells. We used 13C6-glucose, 13C16-palmitate, and gas chromatography-linked mass spectrometry to monitor effects of Firsocostat on glycolytic, Krebs cycle, and fatty acid metabolism. We quantified lipid abundance, apolipoprotein E (ApoE) and vascular endothelial growth factor (VEGF) release using liquid chromatography-mass spectrometry, enzyme-linked immunosorbent assays and localized ApoE deposits by immunostaining. RPE barrier function was assessed by trans-epithelial electrical resistance (TEER). Firsocostat-mediated ACC inhibition increases β-oxidation, decreases intracellular lipid levels, diminishes lipoprotein release, and increases TEER. When human serum or outer segments are used to stimulate lipoprotein release, fewer lipoproteins are released in the presence of either lipid source and Firsocostat. In a culture model of SFD, Firsocostat stimulates fatty acid oxidation, increases TEER, and decreases ApoE release. We conclude that Firsocostat remodels RPE metabolism and can limit lipid deposition. This suggests that ACC inhibition could be an effective strategy for diminishing pathologic drusen in the eyes of patients with AMD or SFD.

Syn and post-glacial volcanic activity in the western retroarc area of the andean southern volcanic zone: Overo volcano

Located in a poorly studied zone of the rear arc in the Transitional Southern Volcanic Zone, the Overo volcano presents a complete record of syn-glacial, inter-glacial, and post-glacial activity, marked by significant changes in eruptive mechanisms over time. Following pre-glacial units, an effusive syn-glacial basaltic phase was succeeded by an extensive inter-glacial diking that fed andesitic monogenetic fields. Subsequently, an eruptive pulse, possibly coupled with the destabilization of the main edifice, resulted in a block and ash deposit channeled into a glacial valley towards the southwest, later covered by extensive basaltic lava flows. Then, different types of pyroclastic flows and glacial deposits covered these earlier units. Finally, these younger glacial deposits were overlain by a localized postglacial pyroclastic deposit and widespread lava flows, which ultimately reconstructed the deeply eroded glacial morphology of the Overo volcano. This volcanic record reveals the young and complex activity of this poorly known western rear-arc volcanic center in the Transitional Southern Volcanic Zone of the Andes, whose evolution is more akin to the arc front volcanoes to the west than to their eastern within-plate counterparts. We propose that this magmatic evolution was influenced by the Pleistocene-Holocene Last Glacial Maximum activity (LGM), beginning with an initial phase of volcanic activity encapsulated within glacial conditions. Glacial retreat then triggered isostatic uplift and crustal relaxation, resulting in dike formation, flank instability, and syn-eruptive collapse of the volcanic edifice. Subsequently, a lesser glacial pulse partially eroded the volcano morphology and produced the currently preserved glacial deposits. Finally, a latest and limited post-glacial pyroclastic eruption occurred simultaneously with the formation of an extensive monogenetic basaltic field, shaping the final morphology of the volcano.

Astragaloside IV relieves passive heymann nephritis and podocyte injury by suppressing the TRAF6/NF-κb axis

The pathogenesis of membranous nephropathy (MN) involves podocyte injury that is attributed to inflammatory responses induced by local immune deposits. Astragaloside IV (AS-IV) is known for its robust anti-inflammatory properties. Here, we investigated the effects of AS-IV on passive Heymann nephritis (PHN) rats and TNF-α-induced podocytes to determine the underlying molecular mechanisms of MN. Serum biochemical parameters, 24-h urine protein excretion and renal histopathology were evaluated in PHN and control rats. The expression of tumor necrosis factor receptor associated factor 6 (TRAF6), the phosphorylation of nuclear factor kappa B (p-NF-κB), the expression of associated proinflammatory cytokines (TNF-α, IL-6 and IL-1β) and the ubiquitination of TRAF6 were measured in PHN rats and TNF-α-induced podocytes. We detected a marked increase in mRNA expression of TNF-α, IL-6 and IL-1β and in the protein abundance of p-NF-κB and TRAF6 within the renal tissues of PHN rats and TNF-α-induced podocytes. Conversely, there was a reduction in the K48-linked ubiquitination of TRAF6. Additionally, AS-IV was effective in ameliorating serum creatinine, proteinuria, and renal histopathology in PHN rats. This effect was concomitant with the suppression of NF-κB pathway activation and decreased expression of TNF-α, IL-6, IL-1β and TRAF6. AS-IV decreased TRAF6 levels by promoting K48-linked ubiquitin conjugation to TRAF6, which triggered ubiquitin-mediated degradation. In summary, AS-IV averted renal impairment in PHN rats and TNF-α-induced podocytes, likely by modulating the inflammatory response through the TRAF6/NF-κB axis. Targeting TRAF6 holds therapeutic promise for managing MN.

Beyond ‘Community Craft Specialisation’ in Prehistoric Mainland Southeast Asian Metallurgy: Copper Smelting Behaviours at Khao Sai On, Nil Kham Haeng, Non Pa Wai, Phromthin Tai, and Tha Kae in Central Thailand

Archaeology in Lopburi Province has been under long-term development since the 1970s and has led to the discovery of Khao Wang Prachan Valley (KWPV) as one of three currently known primary copper production (mining and smelting) sites in Southeast Asia. However, since the 1980s, archaeometallurgical research has focused mainly on the two sites of Non Pa Wai (NPW) and Nil Kham Haeng (NKH), dated from the Neolithic (ca. 1800 B.C.) to Early Iron Age (ca. 2300 B.C.), that are known to have large sequences of archaeological material linked to copper production. Although other sites with evidence of copper production are known in this restricted geographical area, their assemblages have not previously been subjected to archaeometric study. This article discusses the results of archaeometallurgical analyses of slags from Khao Sai On (KSO), Tha Kae (TK), and Phromthin Tai (PTT) with sequences dated during the Middle-Late Iron Age. Slag analysis reveals that different smelting behaviours were occurring at these sites. One heterogenous smelting behaviour at Khao Sai On was probably linked to a smaller community practicing metallurgy among other activities, while Phromthin Tai shows more homogeneous production linked to a larger settlement. Although these three sites are located within 26 km of each other, smelters were probably exploiting different local copper deposits around KWPV. The results seem to support a community based type of production where production behaviours are linked to local geology, technical competence, and intensity of exploitation.

Interaction between active tectonics, bottom-current processes and coral mounds: A unique example in the NW Moroccan Margin, southern Gulf of Cadiz

The NW Moroccan Margin has a complex geological evolution, being located close to the transition zone between the Azores – Gibraltar Fracture Zone and the western front of the Betic–Rif collisional orogen. The interaction between tectonic, halokinetic and fluid flow processes with bottom-current activity shapes the seafloor and influences the distribution of seafloor biological communities (such as the cold-water coral mounds) and deep-water sedimentation. The aims of this work are to study the interaction of the paleo-oceanographic and morpho-tectonic processes that generated the various seafloor features of the NW Moroccan Margin. To achieve this, high-resolution multibeam bathymetry and parasound data acquired in the “ALBOCA II” cruise have been used, complemented by high-resolution 2D seismic reflection data and the EMODnet bathymetric compilation.Several morphological features were identified in the margin, which are related to different processes of sedimentary (contourites and sediment waves), structural (faults and diapirs), gravitational (slide scars, mass transport deposits), fluid migration (mud volcanoes and pockmarks) and biogenic (exposed and buried coral mounds) nature. The structural features (e.g., strike-slip faults) have a major control on the seafloor morphology and, consequently, on the development and evolution of the sedimentary systems in the study area.The evolution of the NW Moroccan Margin during the late Quaternary has been controlled by climatic variations and tectonic activity. The action of these factors has been dominant in distinct parts of the study area where: i) contourite terraces developed when climatic and oceanographic changes were the prevalent factor, ii) mounded and confined contourite drifts and local mass transport deposits formed when the major control was tectonic activity.

The Alluvial Geoarchaeology of the Upper River Kennet in the Avebury Landscape: a Monumental Transformation of a Stable Landscape

Geoarchaeological research as part of the AHRC funded Living with Monuments (LwM) project investigated the upper Kennet river system across the Avebury World Heritage landscape. The results demonstrate that in the early–mid-Holocene (c. 9500–1000 bc) there was very low erosion of disturbed soils into the floodplain, with floodplain deposits confined to a naturally forming bedload fluvial deposit aggrading in a shallow channel of inter-linked deeper pools. At the time of the Neolithic monument building in the 4th–early 3rd millennium bc, the river was wide and shallow with areas of presumed braid plain. Between c. 4000 and 1000 bc, a human induced signature of soil erosion became a minor component of fluvial sedimentation in the Kennet palaeo-channel but it was small scale and localised. This strongly suggests that there is little evidence of widespread woodland removal associated with Neolithic farming and monument building, despite the evidently large timber requirements for Neolithic sites like the West Kennet palisade enclosures. Consequently, there was relatively light human disturbance of the hinterland and valley slopes over the longue durée until the later Bronze Age/Early Iron Age, with a predominance of pasture over arable land. Rather than large Neolithic monument complexes being constructed within woodland clearings, representing ancestral and sacred spaces, the substantially much more open landscape provided a suitable landscape with areas of sarsen spreads potentially easily visible. During the period c. 3000–1000 bc, the sediment load within the channel slowly increased with alluvial deposition of increasingly humic silty clays across the valley floor. However, this only represents small-scale landscape disturbance. It is from the Late Bronze Age–Early Iron Age when the anthropogenic signal of human driven alluviation becomes dominant and overtakes the bedload fluvial signal across the floodplain, with localised colluvial deposits on the floodplain margins. Subsequently, the alluvial archive describes more extensive human impact across this landscape, including the disturbance of loessic-rich soils in the catchment. The deposition of floodplain wide alluvium continues throughout the Roman, medieval, and post-medieval periods, correlating with the development of a low-flow, single channel, with alluvial sediments describing a decreasing energy in the depositional environment.

Applicability of 1D site response analysis to shallow sedimentary basins: A critical evaluation through physics‐based 3D ground motion simulations

AbstractOne‐dimensional site response analysis (1D SRA) remains the standard practice in considering the effect of local soil deposits and predicting site‐specific ground motions, although its range of applicability to realistic seismic wavefields is still in question. In this 1D approach, horizontal and vertical ground shaking are assumed to be induced by vertically propagating shear and compressional waves, respectively. A recent study based on analytical two‐dimensional (2D) plane waves and simple point source earthquake simulations has shown two mechanistic limitations in this 1D modelling technique for general inclined seismic waves, that is, systematic over‐prediction of the vertical motion and wave trapping in the 1D soil column. In this article, we evaluate in detail the applicability of this 1D modelling approach to realistic three‐dimensional (3D) simulated seismic wavefields in shallow sedimentary basins. Linear‐viscoelastic 1D SRA predictions using two types of input motions that are commonly used in practice—rock outcrop and in‐column motions, are compared with the reference true site response results from 3D earthquake simulations in terms of various measures in the frequency and time domain. It is shown that the horizontal motion in the 3D seismic wavefield exhibits dominant shear wave propagation phenomenon, while the vertical motion is a combined effect of compressional and shear waves and can be over‐predicted by the 1D approach when the incident seismic waves are inclined. Direct evidence of the wave refraction process that leads to the vertical motion over‐prediction is provided. 1D SRA with in‐column inputs can yield motions that have significantly longer duration compared to the true 3D site response solution due to trapped waves, casting in doubt the frequent need for increased soil damping in existing site studies to compensate for wave attenuation due to scattering alone. Sensitivity investigation on the increase of soil profile damping by a multiplier Dmul shows Dmul values compatible with those found in the literature for both horizontal and vertical motions. It is shown that the level of Dmul optimized for a best match of the spectral acceleration is dependent on the characteristic of the input motion and a larger Dmul is typically required for the vertical component. In contrast, 1D SRA with outcrop motions predicts motions with shorter significant duration due to its inability to capture the basin‐edge generated surface waves. A suite of ground motion simulations was performed to assess the sensitivity of the observations to the basin geologic structure including the velocity gradient, rock‐basin impedance contrast and basin depth. The analysis results show that the accuracy of the simplified 1D procedure is dependent on the wavefield composition of both the input motions and the true 3D site response solution. While the horizontal motions in shallow sedimentary basins can, to the first order, be reasonably captured by the simplified 1D approach, 1D SRA for the vertical component is in general not reliable and contributions from inclined shear waves should be accounted for in site‐specific evaluation of the vertical design ground motion.

Fingerprinting aeolian sediment sources in the Mu Us Sandy Land using the MixSIAR model

Understanding and quantifying aeolian sediment sources in sand seas is imperative to elucidate their formation mechanism and promote ecological restoration, particularly in transitional zones between agricultural farming and animal grazing. Despite considerable efforts to identify the provenance of the Mu Us Sandy Land (Mu Us), a clear boundary demarcating the provenance differences between its western and eastern regions remains elusive. Furthermore, the quantitative contributions of its potential source areas are yet to be determined. This study elucidated these aspects using robust source indicators and the MixSIAR fingerprinting model, underpinned by geochemical data. Utilizing provenance indicators such as the K/Ba, K/Rb, Ba/Sr, and Rb/Sr ratios, this study identified the line connecting Angsu and Huanghaojie Town as the clear boundary demarcating the provenance differences between the western and eastern Mu Us. The eastern Mu Us's coarse sand primarily derives from underlying sandstones (70.5%) and local fluvio-lacustrine deposits (29.5%), while the western region's coarse sand predominantly originates from Yellow River (YR) sediments in the Yinchuan Basin, transported from the Northeastern Tibetan Plateau (NTP) (82.2%), and local fluvio-lacustrine deposits (17.8%). Similarly, the Mu Us's fine sand mainly originates from local fluvio-lacustrine deposits, contributing 66.5% and 67.6% to the fine sand in the eastern and western regions, respectively. Under strong westerly winds, Gobi deposits from upwind areas contribute 33.5% and 32.4% of fine sediments to the eastern and western Mu Us, respectively. The spatial heterogeneity of material sources in the Mu Us highlights the combined influence of fluvial and wind processes. Lacustrine deposits play a crucial role in the sediment provenance of the Mu Us. This study demonstrates that the MixSIAR model constitutes an effective approach for quantitative provenance research in deserts located in climatic transitional zones worldwide.

A semi-analytical model of RF condensation that can handle localized power depositions

A nonlinear effect, RF (radio frequency) condensation, can be used to facilitate RF stabilization of magnetic islands. Previously studied semi-analytical models for RF condensation are suited mainly for broad deposition profiles and are unable to handle power depositions that are localized in the interior of a magnetic island. The power deposition profile of electron cyclotron waves, in particular, can be highly localized near a cyclotron resonance. Here, a model is developed that can handle both localized profiles and broad profiles. This allows a comparison of RF condensation for narrow vs broad deposition profiles, and it allows a study of the dependence of RF condensation of localized deposition profiles on key parameters.

Demand for U.S Banknotes at Home and Abroad: A Post-Covid Update

In principle, physical currency should be disappearing: payments are increasingly electronic, with new technologies emerging rapidly, and governments increasingly restrict large-denomination notes as a way to reduce crime and tax evasion. Nonetheless, demand for U.S. banknotes continues to grow, and consistently increases at times of crisis both within and outside the United States because dollar banknotes remain a desirable store of value and medium of exchange when local currency or bank deposits are inferior. Most recently, the COVID crisis resulted in historic increases in currency demand. After allowing for the effect of crises, U.S. banknote demand appears to be driven by the usual factors determining money demand, with no discernible downward trend. In this work, I review developments in demand for U.S. currency over the past few decades with a focus on developments since early 2020. In addition, I revisit the question of international demand: I present the raw data available for measuring international banknote flows and updates on indirect methods of estimating the stock of currency held abroad. These methods continue to indicate that a large share of U.S. currency is held abroad, especially in the $100 denomination. As shown earlier (Judson 2012, 2017), once a country or region begins using dollars, subsequent crises result in additional inflows: the dominant sources of international demand over recent decades are the countries and regions that were already heavy dollar users in the early to mid-1990s. While international demand for U.S. currency eased during the early 2000s as financial conditions improved, the abrupt return to strong international demand that began with the collapse of Lehman Brothers in 2008 has not slowed and reached new heights over 2020 and 2021. In contrast, however, the growth rate of demand for smaller denominations is slowing, perhaps indicating the first signs of declining domestic cash demand.

The Manantiales Basin, Southern Central Andes (∼32°S), Preserves a Record of Late Eocene–Miocene Episodic Growth of an East‐Vergent Orogenic Wedge

AbstractThe Manantiales basin contains &gt;4 km of nonmarine sedimentary strata that accumulated at 31.75–32.5°S during construction of the High Andes. We report field and analytical data from the underexplored northern portion of this basin. The basin contains upper Eocene–middle Miocene strata that accumulated in back‐bulge or distal foredeep through inner‐wedge‐top depozones of the Andean foreland basin as it migrated through this region. A revised accumulation history for the basin‐filling Río de los Patos and Chinches Formations supports a regional pattern of flexure in front of an east‐vergent orogenic wedge. The former formation consists of eolian and localized fluviolacustrine deposits which accumulated between ca. 38 Ma and ≤34 Ma during thrust belt development in Chile. A subsequent ≤12 Myr hiatus may reflect passage of the flexural forebulge or cessation of subsidence during orogenic quiescence. The overlying Chinches Formation records a transition from the foredeep to wedge‐top depozones. Foredeep deposits of east‐flowing, meandering streams were incised prior to ca. 18 Ma, after which deposits of axial rivers, playas, and perennial lakes ponded in a depression behind orogenic topography to the east. After ca. 15 Ma, alluvial‐fan deposits were syndepositionally deformed adjacent to growing thrust‐belt structures along the western basin margin. Although the basin record supports a westward step in the locus of deformation during Early–Middle Miocene time, it conflicts with models involving west‐vergence of the orogenic wedge. Rather, this pattern can be explained as out‐of‐sequence deformation alternating with wedge forward propagation, consistent with Coulomb wedge models incorporating syntectonic sedimentation.

Cosmic dust fertilization of glacial prebiotic chemistry on early Earth

AbstractEarth’s surface is deficient in available forms of many elements considered limiting for prebiotic chemistry. In contrast, many extraterrestrial rocky objects are rich in these same elements. Limiting prebiotic ingredients may, therefore, have been delivered by exogenous material; however, the mechanisms by which exogeneous material may be reliably and non-destructively supplied to a planetary surface remains unclear. Today, the flux of extraterrestrial matter to Earth is dominated by fine-grained cosmic dust. Although this material is rarely discussed in a prebiotic context due to its delivery over a large surface area, concentrated cosmic dust deposits are known to form on Earth today due to the action of sedimentary processes. Here we combine empirical constraints on dust sedimentation with dynamical simulations of dust formation and planetary accretion to show that localized sedimentary deposits of cosmic dust could have accumulated in arid environments on early Earth, in particular glacial settings that today produce cryoconite sediments. Our results challenge the widely held assumption that cosmic dust is incapable of fertilizing prebiotic chemistry. Cosmic dust deposits may have plausibly formed on early Earth and acted to fertilize prebiotic chemistry.

Modern methods of industrial wastewater treatment and softening

The growing demand for clean water has significantly increased the need for coagulants in wastewater treatment, particularly for agricultural production organizations. In response to this pressing issue, the provision of iron-rich raw materials to enterprises producing coagulants has become a critical priority. To address this challenge, the paper focuses on exploring the potential of producing coagulants from local iron ore raw materials available in the Karakalpakstan and Navoi regions. Ongoing scientific research efforts are dedicated to studying the composition of the iron ore resources in these mines and determining their potential applications. By leveraging the local iron ore deposits, this approach aims to develop a sustainable and cost-effective solution for the production of coagulants, ultimately supporting the growing demand for clean water in the agricultural sector.

Universal apparatus module of radioactivity logging for the investigation of oil-and-gas reservoirs while drilling

Logging-while-drilling (LWD) is the most advanced technology in geophysical well logging. It is widely used for determining the petrophysical and other parameters of oil-and-gas reservoirs in vertical, deviated, and horizontal boreholes.&#x0D; The LWD is particularly important for horizontal boreholes, obtained by directional drilling from vertical boreholes into predetermined hydrocarbon reservoirs. Horizontal boreholes allow multiplying the yield of hydrocarbons, increasing overall production, and using effectively both new vertical boreholes and exploited ones, as well as old boreholes. The opportunity of horizontal drilling to local (isolated) deposits, which are at a certain distance from vertical boreholes, is of also essential importance. All these factors are favourable for increased hydrocarbon production, which is of great significance for Ukraine.&#x0D; This paper concentrates on the apparatus developments aimed at creating a new module of radioactivity logging for LWD; the module is universal in the sense that it can be used in drill collars, which are employed while drilling all types of boreholes. The tool implements neutron-neutron logging, neutron-gamma logging, gamma-gamma logging, and gamma-ray logging. It allows a direct and combined determination of a broad set of petrophysical reservoir parameters.&#x0D; The advantages and disadvantages of the known nuclear logging modules for the LWD have been analyzed, and the features and merits of the proposed one are shown. During the laboratory and borehole operations with a pilot sample of the module, trends for its improvement were outlined.&#x0D; As an example of using the new module for LWD, the results of determining the petrophysical parameters of oil reservoirs of varying lithology in three horizontal boreholes are given. The process of LWD measurements demonstrated high technologicness and efficiency of the module. Comparison of the obtained parameters of the reservoirs with the data of independent measurements carried out in the open hole of the same boreholes using the PEX tool (Schlumberger) showed a qualitative consistency and a quantitative convergence of the results.

Fossil insectivorous mammals (Eulipotyphla) of the southern Pre-Urals (Bashkortostan, Russia)

Seven species of red-toothed shrews (Sorex araneus, Sorex isodon, Sorex tundrensis, Sorex caecutiens, Sorex minutus, Sorex minutissimus, Neomys fodiens), white-toothed shrews (Crocidura sp.), moles (Talpa sp.) and hedgehogs (Erinaceus sp.) were found in Late Pleistocene and Holocene deposits of the southern part of the western slope of the Ural Mountains. In the Late Pleistocene and Early Holocene deposits, the red-toothed shrews were dominated by S. tundrensis. This species disappeared from the area by the Late Holocene, when S. araneus became the predominant species. Smaller mandibular sizes have been registered for S. araneus in the Middle and Late Holocene, as compared to the sizes of older samples. The morphometric criteria have been established for a species differential diagnosis of the Late Pleistocene – Early Holocene mandibular samples of S. araneus and S. tundrensis, found in local deposits of the southern Pre-Urals area studied.