A layered lattice material composed of cells with multi-configuration is proposed to improve the cushioning performance of lattice materials. The BCCxy (body-centered with XY rods) cells with functional potential are arranged in the GBCC (body-centered cubic) uniform lattice material as the enhanced phase to form the layered structure. Three groups of lattice samples are designed and processed with Inconel 718 and Nylon 6 by additive manufacturing technology. Samples are tested repeatedly by the drop weight impact test system and the impact load, impact action time, impulse and deformation were analyzed to evaluate the cushioning performance of materials. The results show that, compared with the GBCC uniform lattice samples, the maximum impact load, the impulse of the base and the dynamic cushioning coefficient of the layered lattice samples are lowered, the impact action time is prolonged and the outer diameter of the depression on the lattice samples is reduced. It indicates that the cushioning performance of the layered lattice materials with multi-configuration is better than the uniform lattice materials and the local deformation of materials is improved. Meanwhile, it is proved that the number of layers of enhanced phases is an important factor affecting the cushioning performance.