Background: A widely acknowledged fact is that people with more physical activity inclined to possess greater degree of fitness and physical activity can enhance cardiorespiratory health. Aims and Objective: To study the effect of aerobic exercises on peak expiratory flow rate (PEFR), body mass index (BMI), and physical fitness index (PFI) in apparently healthy female subjects. Materials and Methods: This study was conducted after a clearance from institutional ethical committee on 25 apparently healthy female subjects in the age group of 19–35 years who had voluntarily enrolled in a local health club, under the supervision of an expert trainer. The subjects were divided into two groups depending upon the aerobic exercise regimen they followed. They were assessed for height, weight, BMI, body surface area (BSA), PEFR, and PFI by Harvard step test at three different time intervals: 0 week, 6 weeks, and 10 weeks. The mean values of all the parameters were compared and evaluated. Result: There were significant changes (p < 0.001) in all the parameters while comparing with the baseline values at the three time intervals; an increase in PEFR, fall in BMI, and rise in PFI was seen. While comparing the values between the two groups, no significant difference could be found. Conclusion: Any form of aerobic exercise proves to be beneficial if followed consistently. Both the groups experienced an improvement in PEFR, BMI, and PFI, but labeling as which aerobic regimen was better could not be done.