The main objective of this investigation is to find out how biomechanical actions, such as physical activity programs, balanced adjustments, and mindfulness-based posture correction, are successful at reducing Cognitive Load (CL) and levels of stress among college students. Mechanical adjustments decreased stress, physical activity reduced CL, and mindfulness-based posture correction improved Mental Health (MH), according to a long-term experiment with 28 students from four distinct educational fields. Investigators examined students’ stress, CL, and BH levels monthly. The outcome results dealt with all three predictions. A student’s Perceived Stress Scale (PSS) score dropped from 24.66 to 18.10 (mean difference = 6.56, t = 4.82, p = 0.0001) after experiencing practical changes, demonstrating a significant decrease in stress levels. Following the exercise support, CL, as determined by the NASA Task Load Index (NASA-TLX), dropped from 65.38 to 54.23 (mean difference = 11.15, t = 5.29, p = 0.00005). Ratings for BH increased significantly after exercising mindfulness-based posture correction (from 78.63 to 85.13; mean difference = −6.50, t = −4.92, p = 0.00007). The median variation in PF (VO2 Max) went from 40.46 to 45.11 (t = −3.78, p = 0.0012), and the difference in value was −4.65.