In the field of chemical data modeling, it is common to encounter response variables that are constrained to the interval (0, 1). In such cases, the beta regression model is often a more suitable choice for modeling. However, like any regression model, collinearity can present a significant challenge. To address this issue, the Liu-type estimator has been used as an alternative to the maximum likelihood estimator, but it suffers from bias. In this paper, we introduce the Jackknifed Liu-type estimator and its modified version, which demonstrate improved bias reduction compared to the original Liu-type estimator. We assess the theoretical and numerical performance of these estimators through Monte Carlo simulations and real-data examples from the field of chemistry. Our findings highlight the significant improvements offered by the proposed estimators in terms of accuracy and reliability.