Linear Test Model Research Articles

Glycaemic Response to Acute Aerobic and Anaerobic Exercise Performed in the Morning or Afternoon in Healthy Subjects: A Crossover Trial.

The regular practice of physical activity is considered a health promoter and appears to be one of the main contributors to the prevention of chronic diseases. However, the potential effects of exercise on health depending on the time of day at which it is performed have not yet been fully elucidated. To evaluate the effect of physical exercise (aerobic or anaerobic) and chronobiology (morning or afternoon) on the glycemic metabolism of healthy subjects. Healthy subjects participated in aerobic or anaerobic physical exercise sessions, either in the morning or in the afternoon. Blood was drawn from the subjects before, at the end of the exercise and 2 hours after the end of the exercise. Glycemic parameters were analyzed at these time points. A general linear model test was performed after verifying the normal distribution of the raw data (as assessed by the Shapiro-Wilk test) or after a logarithmic/square root transformation, considering aerobic or anaerobic exercise and morning or afternoon exercise as independent variables. Twenty-three subjects (14 women and 9 men) were included in the study. The rate of change in glucose levels was significantly higher at the end of anaerobic exercise compared to aerobic exercise (1.19 ± 0.04 vs. 0.98 ± 0.02, respectively), with a more pronounced decrease in insulin and C-peptide levels following aerobic exercise. In addition, the increase of glucose was higher after the exercise in the morning compared with the afternoon (1.14 ± 0.03 vs. 1.03 ± 0.03, respectively). The type of exercise and chronobiology influence short-term glucose metabolism.

Evidential Analysis: An Alternative to Hypothesis Testing in Normal Linear Models.

Statistical hypothesis testing, as formalized by 20th century statisticians and taught in college statistics courses, has been a cornerstone of 100 years of scientific progress. Nevertheless, the methodology is increasingly questioned in many scientific disciplines. We demonstrate in this paper how many of the worrisome aspects of statistical hypothesis testing can be ameliorated with concepts and methods from evidential analysis. The model family we treat is the familiar normal linear model with fixed effects, embracing multiple regression and analysis of variance, a warhorse of everyday science in labs and field stations. Questions about study design, the applicability of the null hypothesis, the effect size, error probabilities, evidence strength, and model misspecification become more naturally housed in an evidential setting. We provide a completely worked example featuring a two-way analysis of variance.

The Relationship Between Attitudes Towards Academic Self-Efficacy and Self and Peer Assessment in Turkish Nursing Students: A Cross-Sectional Study.

Academic self-efficacy (ASE), as well as self (SA) and peer assessment (PA), is associated with the subjective judgements of the individual. The correlation among these concepts merits further research. This study aims to examine the correlation between nursing students' attitudes towards ASE and SA and PA. This is a correlational cross-sectional study. The sample consisted of 1401 nursing students from five universities in Istanbul, Turkey. The study employed the proportional quota sampling method. The data were collected using a Personal Information Form, View Scale for Peer and Self-Assessment and ASE Scale. Descriptive statistics and multiple linear regression model (stepwise) tests were used to analyse the data. Descriptive statistics revealed that 82.2% of the participants were female and their Academic Grade Point Average was 3.00 ± 0.48. As a result of the regression analysis, it was determined that students' age, gender, perception of academic achievement, status of receiving PA training and attitudes towards doing PA and self-assessment significantly predicted their ASE score. Students' ASE was found to be medium-level, their attitudes towards peer and self-assessment were high and SA and PA attitudes was associated with ASE. A total of 1401 undergraduate nursing students from five undergraduate universities participated in the study and responded to questions on ASE, peer assessment, self assessment, etc.

Novel lateral tunnel Fontan operation in children promotes continued pathway growth into adulthood

ObjectiveMost Fontan operation techniques currently used in children are limited by a blood flow pathway with no growth potential. The external pericardial lateral tunnel Fontan is a novel technique using the patient's pedicled pericardium and atrial wall in situ to create a Fontan pathway. We hypothesize that viable, autologous tissue will allow growth potential of the pathway and adapt to increasing physiologic demands of somatic growth. MethodsWe performed a single-center retrospective review of serial echocardiographic measurements of the inferior vena cava junction and mid tunnel in patients with an external pericardial lateral tunnel Fontan. Linear mixed model and Pearson correlation tests were used for analysis of changes in pathway size with time and body surface area. ResultsA total of 1592 echocardiographic studies from 172 patients up to 23 years after the procedure were identified. Significant enlargement of the pathway at the inferior vena cava junction and mid tunnel was observed over time (P < .0001, P < .0001, respectively). There is a strong positive correlation between increasing size of the inferior vena cava junction and increasing body surface area (R = 0.81, P < .0001). There is also a strong positive correlation between increasing size of the mid tunnel with increasing body surface area (r = 0.67, P < .0001). ConclusionsThe external pericardial lateral tunnel Fontan technique creates a Fontan pathway that enlarges into adulthood. The correlation of increasing pathway size with increasing body surface area suggests pathway growth, responding to increasing physiologic demands of somatic growth into adulthood. Further studies are needed to investigate the impact of this novel technique on Fontan physiology and long-term patient outcomes.

A dual-penalized approach to hypothesis testing in high-dimensional linear mediation models

The field of mediation analysis, specifically high-dimensional mediation analysis, has been arousing great interest due to its applications in genetics, economics and other areas. Mediation analysis aims to investigate how exposure variables influence outcome variable via mediators, and it is categorized into direct and indirect effects based on whether the influence is mediated. A novel hypothesis testing method, called the dual-penalized method, is proposed to test direct and indirect effects. This method offers mild conditions and sound theoretical properties. Additionally, the asymptotic distributions of the proposed estimators are established to perform hypothesis testing. Results from simulation studies demonstrate that the dual-penalized method is highly effective, especially in weak signal settings. Further more, the application of this method to the childhood trauma data set reveals a new mediator with a credible basis in biological processes.

Pengaruh Komitmen dan Motivasi Kerja terhadap Organizational Citizenship Behavior pada Karyawan PT. Vadhana Internasional Duri

This research aims to determine the influence of commitment and motivation on of PT. Vadhana Internasional Duri employees. This research uses quantitative methods with a sampling technique using Total Sampling. The population in this study was all 73 employees of the PT. Vadhana Internasional Office. The data collection techniques used were observation and questionnaires. The data analysis technique used is the Multiple Linear Regression Model and Hypothesis testing using the T Test and F Test and Coefficient of Determination, where previously the data had been tested using the Validity Test and Reliability Test. The research results show that Commitment and Motivation have a significant effect on the OCB behavior of PT. Vadhana Internasional employees. Simultaneously, Commitment and Motivation have a significant effect on OCB behavior. The adjusted coefficient of determination (adjusted R2) is 0.0442, which means that the Commitment and Motivation variables contribute to the influence of OCB behavior by 44.2% while the remaining 55.8% is determined by other variables outside this research. This shows that there are still other variables that can explain OCB behavior

A Heteroscedasticity-Robust Overidentifying Restriction Test with High-Dimensional Covariates

This article proposes an overidentifying restriction test for high-dimensional linear instrumental variable models. The novelty of the proposed test is that it allows the number of covariates and instruments to be larger than the sample size. The test is scale-invariant and robust to heteroscedastic errors. To construct the final test statistic, we first introduce a test based on the maximum norm of multiple parameters that could be high-dimensional. The theoretical power based on the maximum norm is higher than that in the modified Cragg-Donald test, the only existing test allowing for large-dimensional covariates. Second, following the principle of power enhancement, we introduce the power-enhanced test, with an asymptotically zero component used to enhance the power to detect some extreme alternatives with many locally invalid instruments. Finally, an empirical example of the trade and economic growth nexus demonstrates the usefulness of the proposed test.

The impact of various substrates, ceramic shades, and brands on the ultimate color and masking capacity of highly translucent monolithic zirconia: an in vitro study.

This study aimed to examine the impact of substrates, ceramic shades, and brands on the color and masking ability of highly translucent monolithic zirconia (HTMZ) using CIELab and CIEΔE2000 metrics. A total of 156 1-mm thick HTMZ disks in shades A1, A2, and A3 were produced using Dental Direkt and Kerox zirconia brands. Four 3-mm thick substrates (nickel-chromium alloy, non-precious gold alloy (NPG), zirconia shade A2, and resin composite shade A2) were prepared. HTMZ disks were overlaid on these substrates, and color measurements were taken with a spectrophotometer. Color differences (ΔE) were analyzed using CIELab and CIEΔE2000 formulas. The influence of brand, shade, substrate, and their interactions on ΔE values was assessed with a General Linear Model (GLM) and LSD pairwise comparison test. Spearman's correlation test examined the relationship between CIELab and CIEΔE2000 values. Results indicated that ΔEab was significantly influenced by substrate type and shade, while ΔE2000 was also affected by the ceramic brand. Mean color differences across ceramic-substrate groups were within clinically acceptable and perceptible ranges (clinically perceptible: ∆Eab ≥ 1.3 and ∆E2000 ≥ 0.8; clinically acceptable: 0.8 < ∆E2000 ≤ 1.8 and 1.3 < ∆Eab ≤ 2.7), except for NPG, which had ΔE values exceeding the perceptible range (ΔE2000: 1.1 ± 0.11 to 1.8 ± 0.31; ΔEab: 1.61 ± 0.15 to 2.16 ± 0.36). A significant correlation (r = 0.974, P < 0.001) was found between ΔEab and ΔE2000. Various ceramic brands and shades led to notable ΔE variations, yet average color differences within all ceramic-substrate groups remained clinically acceptable. Both ΔEab and ΔE2000 were reliable methods with a strong correlation for measuring color differences.

Weak identification in discrete choice models

We study the impact of weak identification in discrete choice models, and provide insights into the determinants of identification strength in these models. Using these insights, we propose a novel test that can consistently detect weak identification in commonly applied discrete choice models, such as probit, logit, and many of their extensions. Furthermore, we demonstrate that when the null hypothesis of weak identification is rejected, Wald-based inference can be carried out using standard formulas and critical values. A Monte Carlo study compares our proposed testing approach against commonly applied weak identification tests. The results simultaneously demonstrate the good performance of our approach and the fundamental failure of using conventional weak identification tests for linear models in the discrete choice model context. Lastly, we apply our approach in two empirical examples: married women labor force participation, and US food aid and civil conflicts.

Influence of viscosity and fiber reinforcement of resin composite on fracture strength and failure mode of restored molars.

To evaluate the fracture behavior of human molars with extensive MOD restorations using short-fiber-reinforced resin composite of varying viscosities. Human molars were randomly divided into seven groups (n = 12): intact teeth (control); restoration using conventional high-viscosity resin composite without (Filtek Z350XT, 3M) or with fibers (everX Posterior, GC); conventional low-viscosity resin composite without (Filtek Supreme Flowable, 3M) or with fibers (everX Flow Dentin Shade, GC); bulk-fill low-viscosity resin composite (Filtek Bulk Fill Flow, 3M) or with fibers (everX Flow Bulk Shade, GC). Restorations were performed on extensive MOD preparations, following the manufacturers' recommendations for each material. Specimens underwent fracture strength testing (N) and fracture pattern (%) categorized as repairable, possibly repairable, or non-repairable. Results were analyzed using a generalized linear model (N) and Fisher's exact test (%), with α = 0.05. Restorations performed with high-viscosity materials showed fracture strength values similar to the control and higher than those of restorations using low-viscosity resin composites (p < 0.0001), except for the bulk-fill low-viscosity resin composite with fibers (p > 0.05). Teeth restored using low-viscosity resin composite with fibers showed a higher % of repairable and possibly repairable fractures than the control (p = 0.0091). The viscosity of materials mediated the fracture strength, with restorations using high-viscosity resin composites promoting values similar to the intact tooth; however, the presence of fibers influenced the fracture pattern. Teeth with MOD cavities restored with high-viscosity resin composites showed similar fracture strength to intact teeth. Fiber-reinforced low-viscosity resin composite for the base of restoration resulted in a more repairable/possibly repairable fracture pattern.

Exogeneity tests and weak identification in IV regressions: Asymptotic theory and point estimation

This paper provides new insights on exogeneity tests in linear IV models and their use for estimation, when identification fails or may not be strong. We make two main contributions. First, we show that Durbin-Wu-Hausman (DWH) and Revankar-Hartley (RH) exogeneity tests have correct level asymptotically, even when the first-stage coefficient matrix (which controls identification) is rank-deficient. We provide necessary and sufficient conditions under which these tests are consistent. In particular, we show that test consistency can hold even when identification fails, provided at least one component of the structural parameter vector is identifiable. Second, we study point estimation after estimator (or model) selection, when the outcome of a DWH/RH test determines whether OLS or an IV method is employed in the second-stage. For this purpose, we use (non-local) concepts of asymptotic bias, asymptotic mean squared error (AMSE), and asymptotic relative efficiency (ARE), which remain applicable even when the estimators considered do not have moments (as can happen for 2SLS) or may be inconsistent. We study the asymptotic properties of OLS, 2SLS, and pretest estimators which select OLS or 2SLS based on the outcome of a DWH/RH test. We show that: (i) OLS typically dominates 2SLS estimator asymptotically for MSE across a broad spectrum of cases, including weak identification and moderate endogeneity; (ii) exogeneity-pretest estimators exhibit consistently good performance and asymptotically dominate both OLS and 2SLS. The proposed theoretical findings are documented by Monte Carlo simulations.

The influence of information technology and compensation on the employees performance of the regional revenue and financial management agency

The objectives of this study were 1) to determine the effect of Information Technology on performance at the Regional Financial and Revenue Management Agency (BPKPD) of Tomohon City; 2) To determine the effect of Compensation on employee performance at the Regional Financial and Revenue Management Agency (BPKPD) of Tomohon City; 3) To determine the effect of Information Technology and Compensation simultaneously on employee performance at the Regional Financial and Revenue Management Agency (BPKPD) of Tomohon City. The research method used is quantitative research method. Primary data were obtained through questionnaires distributed to 70 employees as research samples. Research data testing techniques include using validity tests, reliability tests, multiple linear regression model tests, hypothesis tests, and coefficient of determination tests. The results showed that 1) There is a positive functional influence that contributes between Information Technology and employee performance; 2) There is a positive functional influence that contributes between compensation and employee performance; 3) There is a positive functional influence that contributes between Information Technology and Compensation together on Employee Performance.

Comparison of motion sensor and heart rate monitor for assessment of physical activity intensity in stroke outpatient rehabilitation sessions: an observational study.

To compare the estimation of time spent on 4 categories of physical activity intensity (sedentary behaviour, light physical activity, moderate physical activity, and vigorous physical activity) between a motion sensor and a heart rate monitor during a stroke outpatient rehabilitation session. A multicentre cross-sectional observational study. Participants with stroke (> 6 months) undergoing outpatient rehabilitation sessions. Participants wore the SenseWear Armband motion sensor and the Polar H10 heart rate monitor during 2 rehabilitation sessions. The times estimated by each device were compared using a generalized linear mixed model and post-hoc tests. Ninety-nine participants from 29 clinics were recruited and data from 146 sessions were included in the analysis. The estimated times depended on the devices and the physical activity intensity category (F = 135, p < 0.05). The motion sensor estimated more time spent in sedentary behaviour and less time spent in moderate physical activity and vigorous physical activity than the heart rate monitor. The motion sensor and heart rate monitor provide different estimates of physical activity intensity during stroke rehabilitation. Further research is needed to establish the most appropriate device for each physical activity category.

Pharyngeal adaptation to bolus properties in patients with Parkinson’s disease

PurposeDysphagia is common in people with Parkinson’s disease (PD). Yet, literature describing swallow function in PD using high-resolution manometry is limited. This study explored swallowing pressure metrics for varied bolus conditions in people with PD.MethodA solid-state unidirectional catheter was used to acquire manometric data for triplicate swallows (5 ml, 10 ml, 20 ml; IDDSI 0, 2 & 4). Penetration-aspiration severity was rated during videofluoroscopy. Patient-reported measures included PDQ-8: Parkinson’s Disease Questionnaire-8 and EAT-10: Eating Assessment Tool-10. Quantitative manometric swallow analysis was completed through Swallow Gateway™. Metrics were compared to published normative values and generalized linear model tests explored modulatory effects.Results21 participants (76% male; mean age 69.6 years, SD 7.1) with mild-moderate severity PD were studied. Two patients (9%) aspirated for single bolus thin liquid and paste trials and 15 patients (73%) scored > 3 EAT-10. Standardized PDQ-8 scores correlated with EAT-10 (p < 0.05). Abnormality in UES relaxation and distension was demonstrated by high UES integrated relaxation pressure and low UES maximum admittance (UES MaxAdm) values across varied bolus conditions. Participants demonstrated abnormally elevated pharyngeal contractility and increased post-swallow upper-esophageal sphincter (UES) contractility for thinner liquid trials. Alterations in volume and viscosity had significant effects on the bolus timing metric—distention to contraction latency. UES peak pressure measures were altered in relation to bolus viscosity.ConclusionThis study identifies early pharyngoesophageal contractile changes in relation to bolus volume and viscosity in PD patients, associated with subtle deterioration of self-reported swallow scores. Manometric evaluation may offer insight into PD-related swallowing changes and help optimize diagnostics and treatment planning

THE INFLUENCE OF PRODUCT QUALITY, PRICE PERCEPTION AND LOCATION ON CUSTOMER SATISFACTION AT WARMINDO BAROKAH KEDUNGMUNDU

The purpose of this research is to analyze the influence of product quality, price perception and location on customer satisfaction at Warmindo Barokah Kedungmundu. The population in this study were Warmindo Barokah Kedungmundu customers. The research method used was purposive sampling. The data used were 99 respondents using the questionnaire data collection method. Data analysis uses instrument tests, multiple linear analysis and model tests. The results from respondent data prove that product quality has a positive effect on customer satisfaction. Price perception has no effect on customer satisfaction and location has a positive effect on customer satisfaction.

The Influence of Zakat Fund and Macroeconomic Variable on Economic Development in Indonesia and Bangladesh

This study aims to analyze the effect of zakat funds and macroeconomic variables on economic development in Indonesia and Bangladesh for the 2010-2019 period. This study uses secondary data with a time series data model of zakat funds, macroeconomic variables consisting of taxes, unemployment, economic growth (GDP), poverty, and the human development index (HDI) from both countries. Furthermore, the data were tested using multiple linear regression models and simultaneous model tests, to obtain test results and complex analysis of the effects of exogenous and endogenous variables on the economic development of the two countries, with the help of the EVIEWS application version 9. The results showed that zakat funds had an effect on positive and significant effect on economic growth in both countries, taxes have a negative and insignificant effect on economic growth in both countries, poverty has a positive and insignificant effect in Indonesia, and insignificant negative in Bangladesh. While the results of the influence of the simultaneous model include; there is a simultaneous effect of zakat, unemployment, and poverty on economic growth in Indonesia and Bangladesh. There is no simultaneous effect between the variables of tax, unemployment, and poverty on economic growth, and there is a simultaneous effect between the variables of the human development index (HDI), poverty, and unemployment on economic growth in Indonesia and Bangladesh.

Vitrification of feline ovarian tissue: Comparison of protocols based on equilibration time and temperature

Global contraction of biodiversity pushed most members of Felidae into threatened or endangered list except the domestic cat (Felis catus) thence preferred as the best model for conservation studies. One of the emerging conservation strategies is vitrification of ovarian tissue which is field-friendly but not yet standardized. Thus, our main goal was to establish a suitable vitrification protocol for feline ovarian tissue in field condition. Feline ovarian tissue fragments were punched with biopsy punch (1.5 mm diameter) and divided into 4 groups. Group 1 was fresh control (Fr), while the other three were exposed to 3 vitrification protocols (VIT_CT, VIT_RT1 and VIT_RT2). VIT_CT involved two step equilibrations in solutions containing dimethyl sulfoxide (DMSO) and ethylene glycol (EG) for 10 min each at 4 °C. VIT_RT1 involved three step equilibration in solutions containing DMSO, EG, polyvinylpyrrolidone and sucrose for 14 min in total at room temperature, while in VIT_RT2 all conditions remained the same as in VIT_RT1 except equilibration timing which was reduced by half. After vitrification and warming, fragments were morphologically evaluated and then cultured for six days. Subsequently, follicular morphology, cellular proliferation (expression of Ki-67, MCM-7) and apoptosis (expression of caspase-3) were evaluated, and data obtained were analysed using generalised linear mixed model and chi square tests. Proportions of intact follicles were higher in Fr (P = 0.0001) and VIT_RT2 (P = 0.0383) in comparison to the other protocols both post warming and after the six-day culture. Generally, most follicles remained at primordial state which was confirmed by the low expression of Ki-67, MCM-7 markers. In conclusion, VIT_RT2 protocol, which has lower equilibration time at room temperature has proven superior thus recommended for vitrification of feline ovarian tissue.

Effect of authentic leadership on nurses’ stress, burnout, presenteeism during COVID-19

PurposeThe COVID-19 pandemic has burdened the health-care system and exposed nurses to immense stress. This study therefore aims to investigate nurses’ mental well-being who are working with COVID-19-positive patients. Burnout leads to decreased productivity and manifests as emotional exhaustion, depersonalisation (cynicism) and low personal accomplishment (professional efficacy). Authentic leadership is built on a humanistic value system, which is the core value of nurses and other health-care professionals. This study therefore used authentic leadership as the independent variable.Design/methodology/approachA cross-sectional quantitative research method was adopted by distributing validated online questionnaires to 1,334 nurses in a private pathology laboratory and 241 questionnaires were analysed with 93.4% female respondents. Multiple linear regression model testing was conducted.FindingsMultiple regression analyses showed statistically significant negative correlations between authentic leadership and emotional exhaustion, cynicism, job stress and job-stress-related presenteeism, and a positive correlation between authentic leadership and professional efficacy.Practical implicationsThis study provides empirical data to encourage organisations to focus on developing authentic leaders to decrease nurses’ burnout, job stress and presenteeism. The health-care sector should strive to create an environment where nurses are valued and their talent is recognised to increase employee engagement and commitment.Originality/valueThere were two contributions in this study: first, to determine whether there is a relationship between authentic leadership job stress and job-stress-related presenteeism. Second, to determine whether there is a relationship between authentic leadership and the three sub-constructs of burnout.

Identification of the ADH1C|FspI gene polymorphism and its association with flavor and odor in Indonesian local sheep

Sheep meat’s flavor and odor may not be as appealing to Indonesians, necessitating genetic improvements in these aspects. The ADH1C (Alcohol Dehydrogenase 1C) gene significantly influences the conversion of ethanol to acetate in liver tissue, directly impacting sheep meat’s flavor and odor. The purpose of this study was to see how ADH1C gene polymorphisms affected sheep meat flavor and odor in Indonesian sheep. The study utilized a sample of 100 rams, including 10 Javanese fat-tailed (JFT), 78 Javanese thin-tailed (JTT), and 12 Jonggol sheep (JS), all aged between 10 and 12 months. To identify polymorphisms and associations of ADH1C|FspI, the researchers employed Polymerase Chain Reaction-Restriction Fragment Length Polymorphism (PCR-RFLP) and General Linear Model (GLM) tests. The results revealed polymorphisms in the ADH1C gene, with two genotypes observed: CG (440, 275, 165 bp) and GG (440 bp). These genotypes were found to be in Hardy-Weinberg Equilibrium (HWE). Moreover, the ADH1C gene displayed a significant (P<0.05) association with 4-methyl octanoic (MOA) and 4-methyl nonanoic (MNA) compounds, with the GG genotype exhibiting the lowest flavor and odor contents. The study suggests that ADH1C with SNP g.25288858 C>G could potentially serve as a marker for selecting Indonesian sheep with a lower flavor and odor.

In-office Bleaching Activated With Violet LED: Effect on Pulpal and Tooth Temperature and Pulp Viability.

This study evaluated the influence of hydrogen peroxide (HP) with or without titanium dioxide nanotubes (TiO2) associated with violet LED (VL) regarding: a) the temperature change in the pulp chamber and facial surface; b) the decomposition of HP; and c) the cytotoxicity of the gels on pulp cells. The experimental groups were: HP35 (35% HP/Whiteness HP, FGM); HP35+VL; HP35T (HP35+TiO2); HP35T+VL; HP7 (7.5% HP/White Class 7.5%, FGM); HP7+VL; HP7T (HP7+TiO2); and HP7T+VL. TiO2 was incorporated into the bleaching gels at 1%. Eighty bovine incisors were evaluated to determine temperature change in 8 experimental groups (n=10/group). A k-type thermocouple was used to evaluate the temperatures of the facial surface and in the pulp chamber, achieved by enabling endodontic access to the palatal surface, throughout the 30-minute session. HP decomposition (n=3) of gels was evaluated by using an automatic potentiometric titrator at the initial and 30-minute time points. Trans-enamel and trans-dentinal cell viability were assessed with a pulp chamber device as well as enamel and dentin discs (n=6), and the treatment extracts (culture medium + diffused components) were collected and applied to MDPC-23 odontoblast cells to evaluate cell viability according to the MTT test. A temperature increase in the pulp chamber was observed in the presence of VL at 30 minutes (p<0.05) (Mann-Whitney test). Also at 30 minutes, HP35 showed greater decomposition in the presence of VL rather than in its absence (p<0.05) (mixed linear models and the Tukey-Kramer test). HP7 provided greater cell viability than the groups treated with HP35 (p<0.05) (generalized linear models test). Cell viability was significantly lower for HP7 in the presence of VL (p<0.05). Pulpal temperature increased with VL (maximum of 1.9°C), but did not exceed the critical limit to cause pulp damage. Less concentrated HP resulted in higher cell viability, even when associated with VL.