Limited Life Research Articles

The current situation and associated factors of preoperative frailty in elderly patients undergoing abdominal surgery

BackgroundThis study aimed to investigate the current preoperative frailty status of elderly patients undergoing abdominal surgery and identify its associated factors. The objective of this study was to provide clinicians with valuable insights for implementing frailty intervention strategies.MethodsA cross-sectional study was conducted with 375 elderly patients who underwent abdominal surgery at a tertiary hospital in Chengdu, Sichuan Province, between October 2021 and August 2022. The data were collected using various instruments, including a general information questionnaire, the FRAIL frailty assessment scale, the West China Mood Index, the Nutritional Risk Screening 2002, and the Barthel Index. Multivariate logistic regression analysis was conducted to investigate the factors influencing preoperative frailty in this patient population.ResultsAmong the 375 elderly patients who underwent abdominal surgery, 59 were identified as having preoperative frailty, resulting in a preoperative frailty rate of 15.7%. Multivariate analysis revealed that multiple chronic diseases, malnutrition risk, and limited ability to perform daily life activities were significant associated factors for preoperative frailty in these patients (P < 0.05).ConclusionClinical medical staff should prioritize the preoperative frailty assessment of elderly patients undergoing abdominal surgery, particularly those with multiple chronic diseases, malnutrition risk, and limited daily life activities.

New Mechanisms of Phase Transition in Olivine‐Type LixMn0.7Fe0.3PO4 Cathodes: a Finding on Relaxation Behavior and its Implications for Battery Performance

AbstractPhosphates of the olivine type, LiMnyFe1‐yPO4 (LMFP), have garnered significant attention due to their higher energy density compared to LiFePO4 (LFP). However, their limited cycle life and rate performance remain key obstacles to their commercialization. Therefore, elucidating the intricate phase transition mechanisms during electrochemical cycling is paramount to overcoming this bottleneck. This study investigates the relaxation behavior of LixMn0.7Fe0.3PO4 (0≤x≤1) under various conditions revealed a remarkable memory characteristic in its crystal structure: the lattice parameters of different delithiated states return to their fully lithiated configuration upon complete relaxation. Moreover, the relaxation rate is influenced by the charging/discharging conditions and storage environment: higher rates, greater delithiation, and longer relaxation times are observed, as are extended relaxation time at lower temperatures and in the absence of electrolyte. These findings provide a rational explanation for the complexity of the phase transition mechanisms in LMFP and highlight the significant differences in phase transition and relaxation behaviors, advancing the understanding of LMFP materials.

Dynamic release electrolyte design for stable proton batteries.

Aqueous proton batteries (APBs) have recently demonstrated unprecedented advantages in the fields of ultralow temperature and high-power energy applications due to kinetically favorable proton chemistry. Proton acids (e.g. H2SO4, H3PO4) as the common proton-conducting electrolyte, however, seriously corrode electrode materials and current collectors, resulting in limited cycle life of APBs. Here we reported protonated amine as a feasible proton transport mediator and releasing source for APBs based on its dynamic chemical dissociation equilibrium. Free protons in the electrolyte are limited to a quite low level. Consequently, the optimized electrolyte with a nearly neutral pH value significantly suppresses corrosion and broadens material selection option for APBs. The CuFe-TBA electrode exhibited a long cycle performance over 40000 cycles with only ~0.0004% attenuation rate per cycle in the optimized electrolyte. The WO3 and VO2(B) electrode also displayed high cycling stability. Benefiting from enhanced electrode stability in the optimized electrolyte, the resultant CuFe-TBA/WO3 and CuFe-TBA/VO2(B) full batteries display impressive long-term cycling performance with high-capacity retention. Our work presents a proton dynamic-release electrolyte for durable APBs which is highly promising for scalable energy systems.

Innovative Eco-friendly Approaches to Enhance the Vase Life of Cut Flowers: A Comprehensive Review

This study investigates the key determinants of cut flower vase life, focusing on the influence of pre- and post-harvest conditions and environmental factors. Addressing the commercial challenges associated with limited vase life, the research underscores the critical need for sustainable and eco-friendly floral preservatives to enhance flower freshness. It highlights the rising interest in plant-based extracts and biodegradable alternatives as effective substitutes for conventional chemical preservatives. These natural preservatives not only improve floral longevity but also reduce environmental impact when paired with optimized post-harvest management practices. The study emphasizes the growing body of research dedicated to extending the shelf life of cut flowers through environmentally conscious solutions. By advancing both flower durability and ecological sustainability, eco-friendly preservatives hold significant potential to revolutionize the floriculture industry.

An optimisation model of hierarchical facility location problem for urban last-mile delivery with drones

Drones have, in recent years, been considered as a promising way for the last-mile delivery of urban logistics. In view of limited or short battery life of drones in every operation, the drone recharging stations and their locations are crucial to ensure delivery accessibility and to accomplish the required mission. Therefore, in addition to considering the selection of service centres and demand nodes, the location of recharging stations should also be incorporated into the proposed model of hierarchical facility location problem (HFLP). Many existing researches on drone recharging station locations assume that the delivery demand is known and only a single path is designed to meet the demand by using queuing theory models to describe node-based service waiting time. However, the reality is that we are still in the infrastructure planning stage for drone delivery, in which the demand is unknown in most cases. Our research proposes a novel mix-integer programming model to solve the HFLP for the last-mile drone delivery in urban areas, aiming to minimise the deployment, operation, and maintenance (DOM) costs of recharging stations, service centres, and paths. We have also incorporated a demand satisfaction constraint into the selection of effective alternative paths that meet the delivery accessibility. On the other hand, a sensitivity analysis in our study reveals varying degrees of impact on DOM costs and effective alternative path quantities, whose results would be useful to practical drone logistics delivery in urban areas.

Upgrading and extending the life cycle of soft robots with in situ free-form liquid three-dimensional printing.

Soft robotics hardware, with numerous applications ranging from health care to exploration of unstructured environments, suffers from limited life cycles, which lead to waste generation and poor sustainability. Soft robots combine soft or hybrid components via complex assembly and disassembly workflows, which complicate the repair of broken components, hinder upgradability, and ultimately reduce their life spans. In this work, an advanced extrusion-based additive manufacturing process, in situ free-form liquid three-dimensional printing (iFL3DP), was developed to facilitate functional upgrades and repairs in soft robots. A yield-stress hydrogel-a type of material that can maintain its shape until sufficient stress is applied-was first printed directly onto the robot surface, serving as a support for printing new components. This technique enabled the fabrication of advanced components with seamless integration onto already assembled robots. These components could combine multiple materials with intricate geometries, including overhangs and high-aspect ratio shapes, that are considerably challenging to manufacture and integrate via traditional methods such as casting. This approach was successfully applied to upgrade an existing soft robot by adding three advanced functionalities: whisker-like sensors for tactile feedback, a grasping mechanism, and a multifunctional passive whisker array. This study showcases the easy repairability of features, new and old, substantially extending the robot's life span. This workflow has potential to enhance the sustainable development of soft robots.

Pt-Doped Co3O4 Nanowires as High-Efficiency Cathodic Catalysts for Improved Lithium-Oxygen Batteries and Insights into The Electrochemical Reaction Pathway

Lithium-oxygen batteries (LOBs) have garnered considerable interest as promising energy storage solutions owing to their exceptional theoretical energy density. Nevertheless, their practical implementation is impeded by notable obstacles, involving suboptimal energy efficiency, excessive overpotential and limited cycle life. Tricobalt tetra-oxide (Co3O4) is a promising cathodic bifunctional catalyst for LOBs. With deliberate alien-atom doping, their catalytic performance can even be further improved due to the resulted structural adjustment. In this work, platinum-doped cobalt oxide nanowires have been hydrothermally synthesized on the acid-treated carbon paper substrates. These nanowires, with a thickness of about 150 nm and a length of approximately 1.5 μm, are closely stacked and display an urchin-like morphology. As employed as the cathode for the LOBs, an excellent performance is delivered, including a discharge capacity of 17079.4 mAh g−1, an overpotential of 0.88 V, a cycle stability of over 75 cycles, and an initial coulombic efficiency of 95.71%, which is superior to the batteries based on pure Co3O4 nanowires. Combined with the results of density functional theory (DFT) calculations, it can be deduced from the experimental observation that the nanowires’ adsorption affinity toward the discharge/charge intermediates of lithium superoxide (LiO2), as well as the morphologies and formation/decomposition pathways of the discharge products, are all governed by Pt-doping. The Pt-doping-improved adsorption induces a transition of the discharge products from the solution-pathway grown flake-like morphologies which are randomly stacked in the voids between pure Co3O4 nanowires to the surface-pathway grown film-like morphologies which are tightly wrapped around the Pt-doped Co3O4 nanowires. The close contact between the film-like discharge products and the Pt-doped Co3O4 nanowires is facile for fast oxygen reduction reaction (ORR) and oxygen evolution reaction (OER) kinetics, hence the lowered overpotential and enlengthened cycle durability of the batteries. Furthermore, the increased amount of the film-like discharge products results in the enhancement of the capacity of the batteries. This work may shed light on approaches for boosting the electrochemical performance of the transition-metal-oxide-based LOBs through the strategy of alien-atom doping.

Determination of wheel polygonal wear limit and fatigue life of railway bogie frames considering wheel/rail excitation

Determination of wheel polygonal wear limit and fatigue life of railway bogie frames considering wheel/rail excitation

Palliative care in advanced systemic rheumatic diseases: an integrated approach

Despite rapid advances in the field of rheumatology, many patients with rheumatoid arthritis suffer from chronic and debilitating systemic disease, with a high symptom burden and limited life expectancy. In...

Versatile Biopolymers for Advanced Lithium and Zinc Metal Batteries.

Lithium (Li) and zinc (Zn) metals are emerging as promising anode materials for next-generation rechargeable metal batteries due to their excellent electronic conductivity and high theoretical capacities. However, issues such as uneven metal ion deposition and uncontrolled dendrite growth result in poor electrochemical stability, limited cycle life, and rapid capacity decay. Biopolymers, recognized for their abundance, cost-effectiveness, biodegradability, tunable structures, and adjustable properties, offer a compelling solution to these challenges. This review systematically and comprehensively examines biopolymers and their protective mechanisms for Li and Zn metal anodes. It begins with an overview of biopolymers, detailing key types, their structures, and properties. The review then explores recent advancements in the application of biopolymers as artificial solid electrolyte interphases, electrolyte additives, separators, and solid-state electrolytes, emphasizing how their structural properties enhance protection mechanisms and improve electrochemical performance. Finally, perspectives on current challenges and future research directions in this evolving field are provided.

Anticoagulation at the end of life: whether, when, and how to treat.

Nearly 2 out of 3 patients with venous thromboembolism (VTE) and 1 out of 4 patients with atrial fibrillation (AF) will die within the year. Whether, when, and how to manage anticoagulation at the end of life requires many trade-offs. Patients and clinicians must balance symptom burden, greatly elevated bleeding and thrombosis risks, competing comorbidities and medications, and changing goals over time. This review uses cases of VTE and AF to present a framework for care that draws upon existing disease-specific data and cutting-edge palliative care science. It reviews strategies for the difficult task of estimating a patient's prognosis, characterizes the enormous public health burden of anticoagulation in serious illness, and analyzes the data on anticoagulation outcomes among those with limited life expectancy. Finally, an approach to individualized decision-making that is predicated on patients' priorities and evidence-based strategies for starting, continuing, or stopping anticoagulation at the end of life are presented.

Intelligent Wireless Charging Path Optimization for Critical Nodes in Internet of Things-Integrated Renewable Sensor Networks.

Wireless sensor networks (WSNs) play a crucial role in the Internet of Things (IoT) for ubiquitous data acquisition and tracking. However, the limited battery life of sensor nodes poses significant challenges to the long-term scalability and sustainability of these networks. Wireless power transfer technology offers a promising solution by enabling the recharging of energy-depleted nodes through a wireless portable charging device (WPCD). While this approach can extend node lifespan, it also introduces the challenge of bottleneck nodes-nodes whose remaining energy falls below a critical value of the threshold. The paper addresses this issue by formulating an optimization problem that aims to identify the optimal traveling path for the WPCD based on ant colony optimization (WPCD-ACO), with a focus on minimizing energy consumption and enhancing network stability. To achieve it, we propose an objective function by incorporating a time-varying z phase that is managed through linear programming to efficiently address the bottleneck nodes. Additionally, a gateway node continually updates the remaining energy levels of all nodes and relays this information to the IoT cloud. Our findings indicate that the outage-optimal distance achieved by WPCD-ACO is 6092 m, compared to 7225 m for the shortest path and 6142 m for Dijkstra's algorithm. Furthermore, the WPCD-ACO minimizes energy consumption to 1.543 KJ, significantly outperforming other methods: single-hop at 4.8643 KJ, GR-Protocol at 3.165 KJ, grid clustering at 2.4839 KJ, and C-SARSA at 2.5869 KJ, respectively. Monte Carlo simulations validate that WPCD-ACO is outshining the existing methods in terms of the network lifetime, stability, survival rate of sensor nodes, and energy consumption.

Immortalized mammosphere-derived epithelial cells retain a bioactive secretome with antimicrobial, regenerative, and immunomodulatory properties

BackgroundThe secretome of primary bovine mammosphere-derived epithelial cells (MDECs) has been shown to exert antimicrobial, regenerative, and immunomodulatory properties in vitro, which warrants its study as a potential biologic treatment with the potential to be translated to human medicine. Currently, the use of the MDEC secretome as a therapy is constrained by the limited life span of primary cell cultures and the decrease of secretome potency over cell passages.MethodsTo address these limitations, early-passage bovine MDECs were immortalized using hTERT, a human telomerase reverse transcriptase. The primary and immortal MDECs were compared morphologically, transcriptomically, and phenotypically. The functional properties and proteomic profiles of the secretome of both cell lines were evaluated and compared. All experiments were performed with both low and high passage cell cultures.ResultsWe confirmed through in vitro experiments that the secretome of immortalized MDECs, unlike that of primary cells, maintained antimicrobial and pro-migratory properties over passages, while pro-angiogenic effects of the secretome from both primary and immortalized MDECs were lost when the cells reached high passage. The secretome from primary and immortalized MDECs, at low and high passages exerted immunomodulatory effects on neutrophils in vitro.ConclusionsHigh passage immortalized MDECs retain a bioactive secretome with antimicrobial, regenerative, and immunomodulatory properties, suggesting they may serve as a consistent cell source for therapeutic use.

Wear-free sliding electrical contacts with ultralow electrical resistivity

Sliding electrical contacts are commonly applied in electrical connectors, such as conductive slip rings, pantographs, switches, and commutators. However, they suffer from several unavoidable problems caused by friction and wear, including high energy consumption, intermittent failures, limited life, and even failure disasters. In this study, we realized an ultralow-friction and long-distance wear-free state, defined as structural superlubricity (SSL), between sliding electrical interfaces under ambient conditions. A conductive SSL can be implemented in experiments with single-crystal graphite flakes on flattened metals, such as Au and Ni films. Furthermore, we found that depositing a 2 to 3-nm-thick diamond-like carbon (DLC) film on a nickel alloy can lead to an even lower resistivity than that of metals alone. In addition, we revealed the mechanism by which DLC films can improve the conductivity between graphite and metals through density functional-theory simulations. In addition, we prepared a prototype of the SSL slip ring and proved that it possessed ultralow friction, was wear-free, and had no intermittent failures. Consequently, our results demonstrate a unique type of electrical-contact interface for applications requiring conduction while sliding. Thus, we opened the door for SSL electromechanical coupling.

Patient-reported outcome measures for life participation in patients with chronic kidney disease: a systematic review

Abstract Background The symptoms, comorbidities and treatment burden associated with chronic kidney disease (CKD) can be debilitating and limit life participation in patients with CKD not requiring kidney replacement therapy (KRT). The aim of this study was to identify the characteristics, content, and psychometric properties of patient-reported outcome measures (PROMs) used to assess life participation in patients with CKD. Methods We searched MEDLINE, Embase, PsycINFO, and CINAHL from database inception to February 2023 for all studies that reported life participation in patients with CKD (Stage 1–5 not requiring kidney replacement therapy). We analyzed the characteristics, dimensions of life participation and psychometric properties of the measures. Results From the 114 studies included, 20 (18%) were randomized trials, 3 (3%) were non-randomized trials, and 91 (80%) were observational studies. Forty-one different measures were used to assess life participation, of which six (15%) were author-developed measures. Twelve (29%) measures assessed life participation specifically, while 29 (71%) measures assessed broader constructs such as quality of life, which included questions relevant to life participation. The 36-Item Short Form Health Survey (SF-36) and Kidney Disease Quality of Life—Short Form (KDQOL-SF) were the most frequently used, in 39 (34%) and 24 (21%) studies, respectively. Many content domains for life participation were assessed including physical activities (walking, running, and sports), social activities, leisure activities, work or study and self-care. None of the measures for life participation were developed specifically for CKD. Four measures (EQ-5D-3 L, FACT-An, SF-6D, and SF-36) had validation data collected in patients with CKD. Conclusion The measures for life participation used in patients with CKD vary in content with few validated in the CKD population. There is a need for a validated measure to assess life participation in a meaningful and consistent way in all patients with CKD worldwide.

Overtreatment of Prostate Cancer Among Men With Limited Longevity in the Active Surveillance Era

Men with limited life expectancy (LE) have historically been overtreated for prostate cancer despite clear guideline recommendations. With increasing use of active surveillance, it is unclear if overtreatment of men with limited LE has persisted and how overtreatment varies by tumor risk and treatment type. To determine if rates of overtreatment of men with limited LE have persisted in the active surveillance era and whether overtreatment varies by tumor risk or treatment type. This cohort study included men with clinically localized prostate cancer in the Veterans Affairs health system who received a diagnosis between January 1, 2000, and December 31, 2019. LE was estimated using the validated age-adjusted Prostate Cancer Comorbidity Index (PCCI). Treatment trends among men with limited LE were assessed using a stratified linear and log-linear Poisson regression in aggregate and across PCCI and tumor risk subgroups. The mean (SD) age for the study population of 243 928 men was 66.8 (8.0) years. A total of 50 045 (20.5%) and 11 366 (4.7%) men had an LE of less than 10 years and LE of less than 5 years based on PCCI scores of 5 or greater and 10 or greater, respectively. Among men with an LE of less than 10 years, the proportion of men treated with definitive treatment (surgery or radiotherapy) for low-risk disease decreased from 37.4% to 14.7% (absolute change, -22.7%; 95% CI, -30.0% to -15.4%) but increased for intermediate-risk disease from 37.6% to 59.8% (22.1%; 95% CI, 14.8%-29.4%) from 2000 to 2019, with increases observed for favorable (32.8%-57.8%) unfavorable intermediate-risk disease (46.1%-65.2%). Among men with an LE of less than 10 years who were receiving definitive therapy, the predominant treatment was radiotherapy (78%). Among men with an LE of less than 10 years, use of radiotherapy increased from 31.3% to 44.9% (13.6%; 95% CI, 8.5%-18.7%) for intermediate-risk disease from 2000 to 2019, with increases observed for favorable and unfavorable intermediate-risk disease. Among men with an LE of less than 5 years, the proportion of men treated with definitive treatment for high-risk disease increased from 17.3% to 46.5% (29.3%; 95% CI, 21.9%-36.6%) from 2000 to 2019. Among men with an LE of less than 5 years who were receiving definitive therapy, the predominant treatment was radiotherapy (85%). Among men with an LE of less than 5 years, use of radiotherapy increased from 16.3% to 39.0% (22.6%; 95% CI, 16.5%-28.8%) from 2000 to 2019. The results of this cohort study suggest that, in the active surveillance era, overtreatment of men with limited LE and intermediate-risk and high-risk prostate cancer has increased in the VA, mainly with radiotherapy.

Transforming Farming: A Review of AI-Powered UAV Technologies in Precision Agriculture

The integration of unmanned aerial vehicles (UAVs) with artificial intelligence (AI) and machine learning (ML) has fundamentally transformed precision agriculture by enhancing efficiency, sustainability, and data-driven decision making. In this paper, we present a comprehensive overview of the integration of multispectral, hyperspectral, and thermal sensors mounted on drones with AI-driven algorithms to transform modern farms. Such technologies support crop health monitoring in real time, resource management, and automated decision making, thus improving productivity with considerably reduced resource consumption. However, limitations include high costs of operation, limited UAV battery life, and the need for highly trained operators. The novelty of this study lies in the thorough analysis and comparison of all UAV-AI integration research, along with an overview of existing related works and an analysis of the gaps. Furthermore, practical solutions to technological challenges are summarized to provide insights into precision agriculture. This paper also discusses the barriers to UAV adoption and suggests practical solutions to overcome existing limitations. Finally, this paper outlines future research directions, which will discuss advances in sensor technology, energy-efficient AI models, and how these aspects influence ethical considerations regarding the use of UAVs in agricultural research.

The Role of Robotic Cystectomy in the Salvage and Palliative Setting: A Retrospective, Single-Center, Cohort Study.

Introduction: This article compares surgical and survival outcomes of robot-assisted and open radical cystectomy with cutaneous ureterostomy for the treatment of frail bladder cancer patients with limited life expectancy. Methods: The institutional database was searched for cystectomy cases with cutaneous ureterostomy, from 1 June 2016 to 31 August 2022. The study population was split into two groups, according to the surgical approach. The baseline characteristics and surgical outcomes were compared. Logistic regression analyses identified predictors of major bleeding events (hemoglobin loss ≥ 3.5 g/dL or blood transfusion) and re-operation within 30 days from surgery. The Kaplan-Meier method estimated the impact of the robotic approach on overall survival and Cox regression analysis assessed its predictors. Results: A total of 145 patients were included: 30% (n = 43) underwent robotic cystectomy. Patients' characteristics and tumor stages distribution were comparable in the two groups but those receiving a minimally invasive treatment showed significantly reduced times to flatus, bowel and hospital discharge (all p < 0.001). Although operation times were longer in this cohort, major bleeding events (60% vs. 89%) and postoperative severe complications (0 vs. 8%) (both p < 0.001) were less frequent compared to the open approach. A logistic regression showed that robotic surgery independently predicted major bleeding events (OR: 0.26; 95%CI 0.09-0.72; p = 0.02) but not the need for re-intervention. A Kaplan-Meier analysis showed that robotic cystectomy was associated with a significant advantage in terms of overall survival (LogRank = 0.03), and this result was confirmed by Cox regression analysis (HR: 0.39; 95%CI 0.14-0.94; p = 0.04). Conclusions: Robotic cystectomy with cutaneous ureterostomy may represent a viable option to treat frail bladder cancer patients, as the minimally invasive approach reduces the risk of bleeding and serious complications and provides a prompt restoration of bowel function and a shorter hospital stay compared to open surgery.

Ultrafast Tailoring Amorphous Zn0.25V2O5 with Precision-Engineered Artificial Atomic-Layer 1T'-MoS2 Cathode Electrolyte Interphase for Advanced Aqueous Zinc-Ion Batteries.

Vanadium (V)-based oxides as cathode materials for aqueous zinc-ion batteries (AZIBs) still encounter challenges such as sluggish Zn2+ diffusion kinetics and V-dissolution, thus leading to severe capacity fading and limited life span. Here, we designed an ultrafast and facile colloidal chemical synthesis strategy based on crystalline Zn0.25V2O5 (c-ZVO) to successfully prepare a-ZVO@MoS2 core@shell heterostructures, where atomic-layer MoS2 uniformly coats on the surface of amorphous a-ZVO. The tailored amorphous structure of a-ZVO provides more isotropic pathways and active sites for Zn2+, thus significantly enhancing the Zn2+ diffusion kinetics during charge-discharge processes. Meanwhile, as an efficient artificial cathode electrolyte interphase, the precision-engineered atomic-layer MoS2 with semi-metallic 1T' phase not only contributes to improved electron transport but also effectively inhibits the V-dissolution of a-ZVO. Therefore, the prepared a-ZVO@MoS2 and conceptually validated a-V2O5@MoS2 derived from commercial c-V2O5 exhibit excellent cycling stability at an ultralow current density (0.05 A g-1) while maintaining good rate capability and capacity retention. This research achievement provides a new effective strategy for various amorphous cathode designs for AZIBs with superior performance.

Ultrafast Tailoring Amorphous Zn0.25V2O5 with Precision‐Engineered Artificial Atomic‐Layer 1T′‐MoS2 Cathode Electrolyte Interphase for Advanced Aqueous Zinc‐Ion Batteries

AbstractVanadium (V)‐based oxides as cathode materials for aqueous zinc‐ion batteries (AZIBs) still encounter challenges such as sluggish Zn2+ diffusion kinetics and V‐dissolution, thus leading to severe capacity fading and limited life span. Here, we designed an ultrafast and facile colloidal chemical synthesis strategy based on crystalline Zn0.25V2O5 (c‐ZVO) to successfully prepare a‐ZVO@MoS2 core@shell heterostructures, where atomic‐layer MoS2 uniformly coats on the surface of amorphous a‐ZVO. The tailored amorphous structure of a‐ZVO provides more isotropic pathways and active sites for Zn2+, thus significantly enhancing the Zn2+ diffusion kinetics during charge–discharge processes. Meanwhile, as an efficient artificial cathode electrolyte interphase, the precision‐engineered atomic‐layer MoS2 with semi‐metallic 1T′ phase not only contributes to improved electron transport but also effectively inhibits the V‐dissolution of a‐ZVO. Therefore, the prepared a‐ZVO@MoS2 and conceptually validated a‐V2O5@MoS2 derived from commercial c‐V2O5 exhibit excellent cycling stability at an ultralow current density (0.05 A g−1) while maintaining good rate capability and capacity retention. This research achievement provides a new effective strategy for various amorphous cathode designs for AZIBs with superior performance.