Most filters used in solid/gas separation are applied in the “dead-end” mode, where the aerosol particles arrive at the filter on trajectories that are approximately perpendicular to it. This study concerns the alternative method of cross-flow filtration, which is in common use for filtering liquids. In this mode, previously studied by Menard et al. [Powder Technol. 71 (1992) 263], Thomas et al. [Powder Technol. 76 (1993) 79] and Ferrer et al. [Powder Technol. 113 (200) 197], some of the flow passes through the filter, depositing particles on the surface, while some sweeps past the surface, causing shear on the deposited cake. Depending on the operating conditions, particle aggregation can occur on the surface and the resulting aggregates can be removed by the through-flow and collected in a downstream device. Laboratory scale equipment has been set up in which a cross-flow filter module is coupled to a cyclone postseparator to separate the aggregates leaving the filter. The filters used were ceramic tubes of 6 cm outside diameter, 4 cm inside diameter and variable lengths. An aerosol of limestone dust particles (mmd=5.0 μm) in ambient air enters the inside of the filter along the axis; due to the aerodynamic conditions within the filter some of the particles are deflected towards the filter and are captured. The results show that the cake is detached in the form of loose agglomerates rather than individual particles, which are easily collected by means of the cyclone. The collection efficiency shown by the cross-flow filter/cyclone combination is over 99% for 5.0 μm (mmd) particles under optimum conditions compared to ≈90% shown by the stand-alone cyclone. This separation efficiency is comparable to that of a surface filter and the pressure loss savings with this system make it an attractive gas cleaning option.