Lifestyle Patterns Research Articles

Association Between Lifestyle Patterns and Abdominal Obesity with Biochemical and Inflammatory Biomarkers in Adolescents with Down Syndrome: The UP&DOWN Study

Association Between Lifestyle Patterns and Abdominal Obesity with Biochemical and Inflammatory Biomarkers in Adolescents with Down Syndrome: The UP&DOWN Study

Effect of fasting on cardiovascular risk factors among healthy adult Muslims attending primary care, Kano, Northern Nigerian.

Cardiovascular diseases (CVD) are among the most prevalent and preventable chronic diseases in the 21st century The global burden of disease: 2004 update. The Report in Sections. A person's risk of developing CVD can be reduced by adopting healthy lifestyles, spiritual and religious practices The American Heart Association Life's Simple 7 in African Americans of the Jackson Heart Study. Fasting as a spiritual practice is not exempted from these benefits. Most world's religions recommend a period of fasting. The obligatory Ramadan fasting in Islam may provide an interesting opportunity to reduce food intake and increase physical activity. The main objective of this study is to investigate the effect of Ramadan fasting on cardiovascular risk factors on healthy adult Muslims. The study was pre/post-test single arm intervention conducted at the staff clinic of Family Medicine department, AKTH, and Northwest, Nigeria. Kano. The study recruited healthy adults 18yrs and above not on any medications that can affect metabolic profiles consecutively from two weeks before Ramadan fasting of 2018 and the last week of Ramadan of the same year. The questionnaire included information on sociodemographic, clinical parameters and Lifestyle pattern. Thirty healthy volunteers were included in this study, 25 males (83.3%) and 5 females (16.7%). The mean age was 38.23 ± 6.35(SD). Twenty-five participants were married (83.3%) with 4 singles (13.3%) and 1 divorcee (3.3%). During Ramadan fasting, weight reduced (67.90 ± 11.61 versus 66.53 ± 12.13 4th week of Ramadan p-value < 0.002) Body Mass Index (22.89 ± 3.63 versus 4th week of Ramadan 22.38 ± 3.64 p-value < 0.002) and systolic blood pressure (120.33 ± 19.91versus 4th week of Ramadan 115.33 ± 14.32 p-value 0.003) reduced significantly compared to baseline. The waist circumference, pulse rate, fasting blood sugar and cholesterol were reduced but were not statistically significant. The result from this study suggested that Ramadan fasting may be a useful means of reducing burden of cardiovascular diseases, as the improved cardiovascular risk factors associated with fasting may translate into a significant health benefit.

Associations of generalized anxiety and social anxiety symptoms with sleep duration, amount of intense exercise, and excessive internet use among adolescents.

Among adolescents, symptoms of generalized anxiety disorder (GAD) and social anxiety disorder (SAD) are not only clinically significant but also continuingly increasing. During adolescence, individuals begin to establish distinct, self-determined lifestyle patterns. This study seeks to identify the associations between such lifestyle factors and the prevalence of GAD and SAD symptoms. The analyzable sample was based on a cross-sectional, nationally representative survey of Finnish 14-18 year old students from comprehensive schools, general upper secondary schools, and vocational institutions. The sample consisted of 60,252 boys and 71,118 girls, with the mean age of 16.05 years (standard deviation 1.06). Symptoms were identified using the GAD-7 (cutpoint of 10), the Mini-SPIN (cutpoint of 6), and the PHQ-2 (cutpoint of 3). Logistic regression models for both GAD and SAD symptoms were stratified by comorbidity group variables. GAD symptoms were closely related to excessive internet use and decreased sleep duration among adolescents, regardless of comorbidity with depression or SAD. SAD symptoms were associated with excessive internet use and a lack of intense exercise, independent of comorbid depression or GAD. The findings underscore the importance of considering lifestyle factors when developing interventions to mitigate GAD and SAD symptoms in adolescents. Interventions and policy recommendations aiming at improving adolescents' health behaviour and mental health should take into account the intertwining of these factors.

Combined lifestyle factors and metabolic syndrome risk: a systematic review and meta-analysis.

The metabolic syndrome is a complex condition influenced by many factors including lifestyle. Recently, more and more studies explored the relationships between combined lifestyle factors (often measured as lifestyle scores/indices) and metabolic syndrome due to the co-occurrence of these factors. These scores/indices considered potential interactions among lifestyle factors, offering a more comprehensive understanding of their relationship with metabolic syndrome. However, no review/meta-analysis has been conducted to summarize existing evidence. Thus, this study aimed to synthesize the associations between lifestyle scores/indices and metabolic syndrome in cross-sectional and cohort studies. A literature search was performed in Embase and Medline. Multivariable-adjusted estimates were synthesized using random-effects models. In research where higher scores indicated better health, we used original estimates directly. In studies where higher scores denoted poorer health, we first calculated the coefficients and standard errors based on original estimates. Afterward, we reversed coefficients' directions and recalculated new estimates. Thus, the pooled estimates compared the healthiest with the least-healthy lifestyles (the highest vs. lowest scores/indices). Subgroup analyses were conducted based on study design, region, baseline time, baseline age, sex, health status, metabolic syndrome diagnosis, and lifestyles' number. Sensitivity analyses were performed by including only high-quality studies and employing leave-one-out analyses. Nineteen studies from 16 publications were included. Physical activity, diet, and smoking were the top three included lifestyle factors. Compared to participants with the least-healthy lifestyles, those with the healthiest lifestyles had a 43% lower metabolic syndrome risk (95% confidence interval = 0.41-0.73). In subgroup analyses, healthy lifestyle scores/indices were inversely associated with both metabolic syndrome prevalence in cross-sectional studies (Odds ratio = 0.62; 95% confidence interval = 0.51-0.73) and metabolic syndrome incidence in cohort studies (Odds ratio = 0.40; 95% confidence interval = 0.11-0.68). The inverse association was consistent in other subgroup and sensitivity analyses. Adherence to a healthy lifestyle pattern was beneficial to metabolic syndrome prevention.

Revisiting, Reframing and Recovering Learning Loss: An Arched Impression on Primary Education During Covid Epoch

Amidst the pandemic phase, students have not learned what they were supposed to learn in normal classroom days while many forgot the lessons taught in pre-pandemic time. As a result of the extended and unprecedented shutdown of schools, educational institutes globally happen to be in a state of unfortunate extremity with prodigious dissipation in the learning process. The present study intended to find out the aspect of learning loss of children consequential to the protracted shutdown of schools. Based on 1200 primary students, the study employs various parametric and non-parametric tests. The study found learning loss about 1.530 points with standard deviation 0.468. Further, though learning loss is not significantly evident among genders but differs regionally. Due to learning loss, numerical skill and hand writing fluency also note a marked difference in many primary classes. The study proposed recommendations for achieving universal primary education during the Covid-19 pandemic era. The study envisaged an exclusive inquiry in the domain of socio-economic literature by scanning the lifestyle patterns of an academic community in a distinct empirical approach. The outcomes delivered from the study undertaken may strive to assist in the formulation of developmental policies for the growth and betterment of future generations.

LEAF: A Lifestyle Approximation Framework Based on Analysis of Mobile Network Data in Smart Cities

The increasing use of mobile networks is an opportunity to collect and model users’ movement data for extracting knowledge about life and health while considering privacy leakage risk. This study aims to approximate the lifestyles of urban residents, employing statistical information derived from their movements among various Points of Interest (PoI). Our investigations comprehend a multidimensional analysis of key urban factors to provide insights into the population’s daily routines, preferences, and characteristics. To this end, we developed a framework called LEAF that models lifestyles by interpreting anonymized cell phone mobility data and integrating it with information from other sources, such as geographical layers of land use and sets of PoI. LEAF presents the information in a vector space model capable of responding to spatial queries about lifestyle. We also developed a consolidated lifestyle pattern framework to systematically identify and analyze the dominant activity patterns in different urban areas. To evaluate the effectiveness of the proposed framework, we tested it on movement data from individuals in a medium-sized city and compared the results with information collected through surveys. The RMSE of 5.167 between the proposed framework’s results and survey-based data indicates that the framework provides a reliable estimation of lifestyle patterns across diverse urban areas. Additionally, summarized patterns of criteria ordering were created, offering a concise and intuitive representation of lifestyles. The analysis revealed high consistency between the two methods in the derived patterns, underscoring the framework’s robustness and accuracy in modeling urban lifestyle dynamics.

Integrating Sustainability and Cultural Sensitivity: Clustering Muslim Tourist Lifestyles in the Andaman Coastal Cluster, Thailand

This study explores the integration of sustainability and cultural sensitivity in clustering Muslim tourist lifestyles in the Andaman coastal region. The Muslim tourist demographic, representing a significant portion of the global population, prioritizes halal standards and Islamic attributes in their travel experiences. This research investigates the lifestyle patterns of Muslim tourists and their alignment with sustainable tourism principles, particularly in Thailand’s Andaman coastal area, known for its marine and beach tourism. A multi-method approach was employed, utilizing the AIO (Activities, Interests, and Opinions) framework for quantitative data collection through the surveys of 836 Muslim tourists, and qualitative insights from in-depth interviews and focus group discussions with local stakeholders. The study identified key lifestyle clusters: Mainstream Travelers, Experience Seekers, and Chillouts, each with specific preferences for halal services, prayer facilities, and eco-friendly accommodations. The findings underscore the importance of a tailored approach in promoting sustainable tourism that respects cultural values. Recommendations include enhancing halal-certified services, improving infrastructure for religious practices, and promoting eco-friendly tourism options. By aligning sustainability with cultural sensitivity, the Andaman coastal region can attract more Muslim tourists while preserving its environmental and cultural heritage. This research contributes to the broader discourse on sustainable tourism by emphasizing cultural sensitivity and provides practical guidelines for tourism stakeholders in the Andaman region to develop inclusive and sustainable tourism strategies.

Studi Sosiolinguistik pada Nadhoman Terjemah Kitab Syu’abul Iman Karya KH. A Wahab Muhsin

Sociolinguistic studies are part of modern linguistic studies which cover all linguistic phenomena and their communities. This study can explain word preferences or language structures that differentiate one literary work from another based on the relationship between individuals, populations, periodization and people's lifestyle patterns. The source of sociolingistics research is all types of communication that use language, both spoken and written in all varieties of languages ​​in the world. This research aims to describe sociolinguistic relationships and traces of their application in Nadhoman's "Translation of Syu'abul Iman". The data used in this research are all aspects of perspective studies which include figurative sentences in the form of symbols, images, figurative language or figures of speech, as well as diction or choice of words as well as expressions in the form of loanwords, theme idioms, diction, language style, imagination and messages that describe the influence sociological and linguistic aspects of the translation of the book Syu'abul Iman by KH.A Wahab Muhsin in the form of a translation of the book Syu'abul Iman which was compiled in 1967. Researchers indicate that there are linguistic values ​​related to the situation and social relations in it. To prove this, the author analyzes it using descriptive qualitative methods. The data collection technique in this research is a reading-note technique. The technique is carried out by reading, taking notes for analysis based on the perspective study. The research results obtained prove that sociolinguistics is very influential on the building blocks of the translation of the book Syu'abul Iman.Keywords: Sociolinguistics, Sundanese Nazhoman, Translation.

A Prospective Cohort Study on Metamorphosis of Peptic Ulcer Dynamics: Insights into High Risk Paramedical Students Transformed Knowledge, Lifestyle and Symptoms Pattern

Background: This study explores the epidemiology of Peptic Ulcer Disease (PUD) among resident students in Komarapalayam, India, with the aim of increasing awareness, identifying influential lifestyle factors, and assessing intervention effectiveness. Methods: A comprehensive nine-month prospective cohort study involving 404 paramedical students aged 17-28 was rigorously conducted. Data collection included a meticulously validated questionnaire, high-risk subgroup identification, and the implementation of educational interventions. Statistical analyses maintained a significance threshold at p ≤ 0.05. Results: The study findings revealed a striking contrast. While the actual incidence of Peptic Ulcer Disease was lower than anticipated, the prevalence of prodromal symptoms was surprisingly high. This underscores the critical need for early symptom identification. Tailored educational interventions exhibited great promise in improving PUD comprehension. Lifestyle choices played a substantial role in susceptibility, with hostellers experiencing the highest PUD prevalence at 10.3%— the efficacy of symptom-based assessments extended beyond healthcare domains. Conclusion: This investigation underscores the urgency of early symptom recognition, personalized education, and proactive health-oriented choices to mitigate the onset of Peptic Ulcer Disease. It highlights the merit of symptom- based assessments and emphasizes the essential role of health education within tertiary institutions. This research catalyzes future initiatives aimed at enhancing the well-being of students in the context of Peptic Ulcer Disease.

Association between healthy lifestyle on life course and multimorbidity in adults: results from two national prospective cohort studies

ObjectivesTo examine the correlation between healthy lifestyle patterns, their change trajectories, and the risk of multimorbidity in adults.MethodsBased on two representative national cohorts, the English Longitudinal Study of Aging (ELSA) and the Health and Retirement Study (HRS) including adults aged 50 years and over. We employed Cox regression, lifestyle change trajectories, and restricted mean survival times to explore the relationship between lifestyle (assessed by SCORE2, LE’8, and HLS scores) and multimorbidity. We also conducted mediation analysis to investigate the underlying mechanisms.ResultsA healthy lifestyle (higher LE’8, higher HLS, or lower SCORE2) can reduce the risk of multimorbidity. 2-10% lower multimorbidity risk per one-point increase in LE’8 and HLS. The hazard ratio of multimorbidity for improvements in unhealthy lifestyles or deterioration in healthy lifestyles compared to always healthy lifestyles ranged from 1.598 to 5.602. Besides, for LE’8 and HLS, participants with higher scores had a slower decrease in survival probability in ELSA. Triglyceride, C-reaction protein, fibrinogen, and cystatin C partly mediate the association between lifestyle and multimorbidity.ConclusionsKeeping a healthy lifestyle over time can help reduce the risk of multimorbidity.

Efficacy and Safety of Sarpogrelate on Symptom Improvement in Patients with Peripheral Arterial Disease (PAD) and/or Being at Risk of PAD: A Single Arm, Multi-Centered, Open-Label Trial.

To assess the efficacy and safety of sarpogrelate (300 mg) for symptom improvement in patients having peripheral arterial disease (PAD) and/or being at risk of PAD in clinical practice using the Peripheral Artery Questionnaire (PAQ). Symptomatic changes with antiplatelets in patients with PAD are limited. To determine the effect and safety of sarpogrelate on the PAQ at 24 weeks from baseline. A total of 1003 patients having PAD and/or being at risk of PAD from 17 tertiary hospitals in South Korea who were treated with sarpogrelate, were enrolled in this study. PAQs were collected at baseline and at 12 and 24 weeks, together with physical examination and vital signs measurements. Lifestyle pattern was also investigated. The average PAQ Summary Score in the efficacy evaluation analysis group significantly improved from 62.9 ± 23.7 at baseline to 68.9 ± 21.7 at 24 weeks (P<0.0001). Physical limitation items significantly improved from 69.5 ± 30.0 at baseline to 72.9 ± 28.3 after 24 weeks (P=0.0011). Symptom stability also significantly improved from 52.1 ± 21.6 at baseline to 63.6 ± 22.9 after 24 weeks (P<0.0001). Symptoms, treatment satisfaction, quality of life, and social limitation domains all improved after treatment. A total of 201 patients reported adverse events (20.0%), not directly associated with treatment. Treatment with 300 mg (orally) of sarpogrelate demonstrated statistically significant improvements in all domains and for the summary score of the PAQ at 24 weeks, it gave good results in terms of safety. Sarpogrelate may be helpful in reducing symptoms related to PAD.

Lifestyle factors as predictors of incident functional somatic disorder. Five-year follow-up of The DanFunD study.

To assess whether lifestyle factors, including sleep pattern, are predictors for the development of functional somatic disorder (FSD). A population-based prospective cohort of 9656 men and women aged 18-76 years was established in 2011-2015 and invited for re-examination in 2017-2020, when 5738 participated. Median follow-up period was 65 months. Participants filled in validated questionnaires on lifestyle, sleep pattern and various delimitations of FSD, which were operationalized using two different approaches: bodily distress syndrome (BDS) and functional somatic syndromes (FSS) (i.e. chronic fatigue, chronic widespread pain (CWP), irritable bowel, and multiple chemical sensitivity (MCS)). Baseline lifestyle and sleep pattern in relation to incidence of BDS and FSS (chronic fatigue, CWP, irritable bowel, MCS) was analysed by logistic regressions, adjusted for age, sex and subjective social status. Inferior sleep quality at baseline predicted both incidence of BDS and all FSS delimitations except MCS. Smoking, alcohol intake, and low physical activity, but not diet, were predictors for the development of BDS. No uniform pattern was observed for the FSS. Smoking predicted development of chronic fatigue, CWP and irritable bowel, but not MCS. Alcohol and food quality only influenced the development of chronic fatigue whereas low physical activity only influenced the development of chronic fatigue and CWP. Lifestyle factors and sleep pattern seem to be predictors for some delimitations of FSD, but the importance of the various lifestyle factors is different for the different delimitations. The study shows the importance of analysing the various FSSs separately.

Research progress of antiviral treatment for patients with chronic hepatitis B combined with metabolic fatty liver disease

Chronic hepatitis B (CHB) mainly causes cirrhosis and hepatocellular carcinoma (HCC). Metabolic fatty liver disease (MAFLD) has become the most common chronic liver disease worldwide with the continuous changes in lifestyle and dietary patterns and the increase in the number of obese individuals. Consequently, the incidence rate of CHB combined with MAFLD is rapidly increasing. However, the pathogenesis, treatment, and clinical prognosis remain unclear due to the interaction between CHB and MAFLD. Notably, in the academic community, there are still controversies as to whether patients with CHB and MAFLD should immediately start antiviral treatment, whether MAFLD affects the antiviral efficacy in CHB patients, and whether nucleos(t)ide analogues (NAs) affect the body's metabolism. This article reviews the epidemiology, clinical prognosis, treatment management strategies (especially the antiviral efficacy of NAs drugs), and NAs drug effects on the body's metabolism in patients with CHB combined with MAFLD so as to provide diagnostic and therapeutic concept for clinicians.

Ancient Practice of Garbh Sanskar and its Importance in Modern Scenario

Garbh Sanskar is ancient practice of nurturing mental, physical and emotional environment of mother during her pregnancy stage to promote overall well-being of both mother as well as her unborn child. This ancient practice combines holistic habits that include balanced nutrition, Yoga, recitation of Mantra, prayer and meditation, etc. This process inculcates positive values in the subconscious mind of Garbh (fetus) and also nourish mother in all means to manifest optimal strength in all dimensions. The practices of Garbh Sanskar maintain well being of mother and child, these effects subsequently reflects in the later stages of pregnancy and after the child birth. The current scenario witnessed hampered pattern of life style which significantly deteriorate health of women carrying fetus, this may cause problem in normal child birth or disrupt health of new born. Therefore practices of Garbh Sanskar become crucial in modern’s day life style to prevent mother and child from the harmful effects of stressful pattern of current scenario. This article highlights ancient practice of Garbh Sanskar and its importance in modern scenario.

Key Risk-Factors Contributing to Cardiovascular Disease: Lifestyle Modifications to Improve Cardiovascular Health

Cardiovascular disease is a preventable public health issue. The aim of this review is to identify modifiable risk-factors for cardiovascular disease and recommend lifestyle modification to prevent cardiovascular disease. PubMed, ScienceDirect, SAGE, Google Scholar, World Health Organisation websites, as well as public and community health textbooks, were hand searched and academic resources which are relevant for this review were selected for inclusion. Cardiovascular disease is leading cause of deaths in all continents of the world. While deaths from cardiovascular disease is increasing in Africa and Asia, it is decreasing in Australia and fluctuating in the USA. Premature deaths from cardiovascular disease are preeminent across middle income countries in Europe compared with high income countries. Cardiovascular disease is higher in rural areas of South America compared with urban areas. Trends in lifestyle patterns, including physical inactivity, smoking behaviour, and diets contribute to cardiovascular disease-prone conditions. Prevention includes health promotion activities that facilitate healthy living across life course and limit the initial onset of cardiovascular disease. Investment in prevention is the critical sustainable solution for the cardiovascular disease epidemic. Adopting WHO existing policies within individual countries in Africa, Asia, and middle-income countries in Europe, and ensuring robust implementation of such policies across life course and from different layers of sectors such as education and workplaces would have wider impacts in reducing risk and cardiovascular disease burden in the respective continents. Government of countries with worsening cardiovascular events should also increase health financing and focus on strengthening primary health care services for prevention and treatment of cardiovascular disease.

Socioeconomic Profiling and Dynamics: Insights from a Rural Community Study in Kedah

This study provides a socio-economic profile of Mahang and Nagalilit, two sub-districts in Kulim, Kedah, Malaysia. Residents of Mahang primarily rely on rubber tapping and oil palm cultivation, industries vulnerable to monsoon weather. In Desa Keda Nagalilit, locals are employed in the nearby hi-tech industrial area, oil palm plantations, or as shop assistants. Many households earn below the minimum wage, compelling residents to take on multiple jobs for financial stability. Data was systematically collected through questionnaires focusing on household demographics, socio-economic conditions, and lifestyle patterns. The analysis offers valuable insights into the living conditions and challenges these communities face, especially in light of the COVID-19 pandemic. The research revealed income disparities and variations in living standards between sub-districts, underscoring the socio-economic impact of the pandemic. It further examined how variables such as age, income, employment status, and education correlate with financial strain, mental health issues, and disruptions to daily life. Findings demonstrate significant relationships between socioeconomic factors and the pandemic's effects, emphasizing the need for targeted measures to alleviate poverty, improve education, and enhance residents’ overall quality of life while addressing financial and mental health challenges

Lifestyle Patterns among Adolescents in Selected Schools of District Rohtak, Haryana: A Cross Sectional Study

Introduction: - Adolescence is a period in which an individual undergoes major physical and psychological changes. There is convincing evidence between lifestyle diseases and unhealthy habits which are acquired during adolescence and persist in adulthood. An early investigation of the lifestyles of adolescents will probably prevent their progression into serious diseases. Methods: - The present cross-sectional study recruited 600 adolescents studying 9th to 12th in the selected schools of Rohtak, Haryana, India. The lifestyle-related behavior and practices were assessed based on a structured proforma with the following domains: - home &amp; environment, education, eating habits, and sexuality. Ethical permission was obtained from the concerned authorities. Results: - The mean age of the study subjects was 15.9 (SD-1.4) and most of them were males (61%). More than half of the study subjects (52.7%) were having BMI of 18 to 25 Kg/m2 and 39.8% of them belonged to lower middle socio-economic status. A major proportion of the students felt happy to go to school (64%) and were regular in attending school (90%). The majority of them reported having some spiritual beliefs (88%). A major proportion of the students reported that they own smartphones (83%) and were using various social networking sites (83%). Around 63% of the subjects reported eating fast food on monthly basis. About 11% of the subjects reported the usage of alcohol in the current 3 months. Around 20% of the subjects reported knowledge regarding HIV/STD. Conclusion: - The study documents the presence of unhealthy dietary practices, higher levels of usage of mobile phones along with alcohol use in the school children in this setting. The current study provides some preliminary data for policymakers so that they can modify the current policies and interventions according to the needs of adolescents.

Lifestyle, meal times, and sleep patterns changes in higher education professors during COVID-19: Association with non-communicable chronic diseases.

In response to the COVID-19 pandemic, educational institutions had to swiftly adapt and transition to remote teaching in order to maintain academic activities. However, these changes presented a number of challenges for professors, which could have negative effects on their health. To analyze the association between changes in dietary and sleep habits, physical activity level, and sedentary behavior with the development of non-communicable diseases (NCDs) among Brazilian higher education professors during the pandemic period. This is a cross-sectional and retrospective study conducted using an online form. Generalized linear models, adjusted for age, sex, and body mass index, were used to verify the difference between pre-pandemic and pandemic periods. Logistic regression models were used to predict the odds ratio (OR) for the development of NCDs according to physical activity time, sedentary behavior time, dietary and sleep patterns. A total of 936 professors residing across Brazil participated in the survey. The duration of sedentary behavior increased, sleep duration slightly decreased, and meal times shifted to earlier during the pandemic. A total of 22.9%of the participants reported the diagnosis of some NCDs during this period. Physical activity practice was associated with a lower risk of diseases during the pandemic, regardless of the intensity performed. On the other hand, late eating habits and excessive food consumption during the pandemic were associated with a higher risk. The results provide data that can help in the development of public policies that promote health actions to minimize the consequences associated with the pandemic period.

Optimal lifestyle patterns for delaying ageing and reducing all-cause mortality: insights from the UK Biobank

BackgroundWith the rapid aging of the global population, identifying lifestyle patterns that effectively delay aging and reduce mortality risk is of paramount importance. This study utilizes the UK Biobank to analyze the associations of the Dietary Inflammatory Index, physical activity, and sleep on biological aging and all-cause mortality.MethodsA prospective cohort study was conducted using data from over half a million UK Biobank participants. Two datasets were created by subjective and objective measurements of physical activity: the Subjective Physical Activity (SPA) and Objective Physical Activity (OPA) datasets. Lifestyle patterns, including diet habits, exercise levels, and sleep quality, were assessed within these datasets. Biological aging was quantified using validated methods, including Homeostatic Dysregulation, Klemera-Doubal Method Biological Age, Phenotypic Age, and Telomere Length. All-cause mortality data were obtained from the National Health Service. Statistical analyses included weighted linear regression and Cox proportional hazard models, adjusted for a range of covariates.ResultsThe findings indicate that, in most cases, maintaining an anti-inflammatory diet, engaging in at least moderate physical activity, and ensuring healthy sleep conditions are associated with delayed physiological aging (Cohen’s d ranging from 0.274 to 0.633) and significantly reduced risk of all-cause mortality (HR-SPA: 0.690, 95% CI: 0.538, 0.884; HR-OPA: 0.493, 95% CI: 0.293, 0.828). These effects are particularly pronounced in individuals under 60 years of age and in women. However, it was observed that the level of physical activity recommended by the World Health Organization (600 MET-minutes/week) does not achieve the optimal effect in delaying biological aging. The best effect in decelerating biological aging was seen in the high-level physical activity group (≥ 3000 MET-minutes/week). The study also highlights the potential of biological age acceleration and telomere length as biomarkers for predicting the risk of mortality.ConclusionsChoosing healthy lifestyle patterns, especially an anti-inflammatory diet, at least moderate physical activity, and healthy sleep patterns, is crucial for delaying aging and reducing mortality risk. These findings support the development of targeted interventions to improve public health outcomes. Future research should focus on objective assessments of lifestyle to further validate these associations.

A Latent Class Analysis of Lifestyle Patterns in Relation to Depressive Symptoms Among Adolescents - Jiangsu Province, China, 2022.

Interventions aimed at modifying lifestyle behaviors can effectively reduce the risk of depression among adolescents. These lifestyle behaviors tend to be interconnected; thus, changes to one behavior can often lead to changes in others, usually occurring simultaneously. Adolescents from Jiangsu Province displayed distinct lifestyle patterns, with those engaging in multiple specific behaviors, such as excessive consumption of sugar-sweetened beverages and prolonged screen time, showing increased odds of depression. Early implementation of anti-depression interventions in adolescents should be advocated and prioritized, particularly targeting multiple high-risk lifestyles.