In this paper, we will study the lower bounds of the life span (the maximal existence time) of solutions to the initial‐boundary value problems with small initial data and zero Neumann boundary data on exterior domain for one‐dimensional general quasilinear wave equations utt−uxx=b(u,Du)uxx+F(u,Du). Our lower bounds of the life span of solutions in the general case and special case are shorter than that of the initial‐Dirichlet boundary value problem for one‐dimensional general quasilinear wave equations. We clarify that although the lower bounds in this paper are same as that in the case of Robin boundary conditions obtained in the earlier paper, however, the results in this paper are not the trivial generalization of that in the case of Robin boundary conditions because the fundamental Lemmas 2.4, 2.5, 2.6, and 2.7, that is, the priori estimates of solutions to initial‐boundary value problems with Neumann boundary conditions, are established differently, and then the specific estimates in this paper are different from that in the case of Robin boundary conditions. Another motivation for the author to write this paper is to show that the well‐posedness of problem is the essential precondition of studying the lower bounds of life span of classical solutions to initial‐boundary value problems for general quasilinear wave equations. The lower bound estimates of life span of classical solutions to initial‐boundary value problems is consistent with the actual physical meaning. Finally, we obtain the sharpness on the lower bound of the life span in the general case and in the special case. Copyright © 2015 John Wiley & Sons, Ltd.