Sequence Of Levels Research Articles

Growth, Productivity and Profitability of Direct Seeded Rice as Influenced by Maize Crop Residue Management Practices and Fertility Levels in Rice-Maize Sequence

Growth, Productivity and Profitability of Direct Seeded Rice as Influenced by Maize Crop Residue Management Practices and Fertility Levels in Rice-Maize Sequence

Accessible Point-and-Tap Interaction for Acquiring Detailed Information about Tactile Graphics and 3D Models.

We have devised a novel "Point-and-Tap" interface that enables people who are blind or visually impaired (BVI) to easily acquire multiple levels of information about tactile graphics and 3D models. The interface uses an iPhone's depth and color cameras to track the user's hands while they interact with a model. When the user points to a feature of interest on the model with their index finger, the system reads aloud basic information about that feature. For additional information, the user lifts their index finger and taps the feature again. This process can be repeated multiple times to access additional levels of information. For instance, tapping once on a region in a tactile map could trigger the name of the region, with subsequent taps eliciting the population, area, climate, etc. No audio labels are triggered unless the user makes a pointing gesture, which allows the user to explore the model freely with one or both hands. Multiple taps can be used to skip through information levels quickly, with each tap interrupting the current utterance. This allows users to reach the desired level of information more quickly than listening to all levels in sequence. Experiments with six BVI participants demonstrate that the approach is practical, easy to learn and effective.

Income Change and Inter-Farmer Relations through Conservation Agriculture in Ishikawa Prefecture, Japan: Empirical Analysis of Economic and Behavioral Factors

Conservation agriculture, also known as environment-friendly agriculture, is expected to contribute to global climate change mitigation and biodiversity conservation. To understand the effect of conservation agriculture on farmers and identify those factors, such as farmers’ income change, that might affect practices of conservation agriculture, perceptions, and output, this study examined farmers’ economic and behavioral factors, motivation, and satisfaction. We surveyed 51 farmers who are receiving subsidies to practice conservation agriculture in Ishikawa Prefecture, Japan. The survey is one of the first prefectural-scale studies that combines unique quantitative analysis of motivation and satisfaction levels (e.g., behaviors) in temporal sequence from the initial to current time to practice conservation agriculture. Our results showed that years of experience, trade with a retail shop, and the farmer’s age can affect income change. With regard to social factors, the satisfaction of their fellowship with other farmers practicing conservation agriculture was also significantly correlated with income change. Simultaneously, this category of satisfaction was difficult to attain compared to the other categories. Thus, greater effort is needed to enhance support networking among conservation farmers. Furthermore, the work presented here also provides the opportunity for future research on temporal and spatial questions surveying economic and behavioral effects with consideration of the heightened policy promotion and entrance of large retail industries.

New phiocricetomyine rodents (Hystricognathi) from the Jebel Qatrani Formation, Fayum Depression, Egypt.

BackgroundThe rich rodent assemblages from the Eocene–Oligocene deposits of the Jebel Qatrani Formation (Fayum Depression, Egypt) have important implications for our understanding of the origin and paleobiogeography of Hystricognathi, a diverse clade that is now represented by the Afro-Asiatic Hystricidae, New World Caviomorpha, and African Phiomorpha.MethodsHere we present previously undescribed material of the enigmatic hystricognath clade Phiocricetomyinae, from two stratigraphic levels in the lower sequence of the Jebel Qatrani Formation—a new genus and species (Qatranimys safroutus) from the latest Eocene Locality 41 (~34 Ma, the oldest and most productive quarry in the formation) and additional material of Talahphiomys lavocati from that species’ type locality, early Oligocene Quarry E (~31–33.2 Ma).ResultsThe multiple specimens of Qatranimys safroutus from L-41 document almost the entire lower and upper dentition, as well as mandibular fragments and the first cranial remains known for a derived phiocricetomyine. Specimens from Quarry E allow us to expand comparisons with specimens from Libya (late Eocene of Dur at-Talah and early Oligocene of Zallah Oasis) that have been placed in T. lavocati, and we show that the Dur at-Talah and Zallah specimens do not pertain to this species. These observations leave the Fayum Quarry E as the only locality where T. lavocati occurs.

Supporting Student Success and Persistence in STEM With Active Learning Approaches in Emerging Scholars Classrooms

Over the last several decades, Emerging Scholars Programs (ESPs) have incorporated active learning strategies and challenging problems into collegiate mathematics, resulting in students, underrepresented minority (URM) students in particular, earning at least half of a letter grade higher than other students in Calculus. In 2009, West Virginia University (WVU) adapted ESP models for use in Calculus I in an effort to support the success and retention of URM STEM students by embedding group and inquiry-based learning into a designated section of Calculus I. Seats in the class were reserved for URM and first-generation students. We anticipated that supporting students in courses in the calculus sequence, including Calculus I, would support URM Calculus I students in building learning communities and serve as a mechanism to provide a strong foundation for long-term retention. In this study we analyze the success of students that have progressed through our ESP Calculus courses and compare them to their non-ESP counterparts. Results show that ESP URM students succeed in the Calculus sequence at substantially higher rates than URM students in non-ESP sections of Calculus courses in the sequence (81% of URM students pass ESP Calculus I while only 50% of URM students pass non-ESP Calculus I). In addition, ESP URM and ESP non-URM (first-generation but not URM) students succeed at similar levels in the ESP Calculus sequence of courses (81% of URM students and 82% of non-URM students pass ESP Calculus I). Finally, ESP URM students’ one-year retention rates are similar to those of ESP non-URM students and significantly higher than those of URM students in non-ESP sections of Calculus (92% of ESP URM Calculus I students were retained after one year, while only 83% of URM non-ESP Calculus I students were retained). These results suggest that ESP is ideally suited for retaining and graduating URM STEM majors, helping them overcome obstacles and barriers in STEM, and increasing diversity, equity, and inclusion in Calculus.

Abstract MP01: Effect Of The DASH-Sodium Diet On Serum Biomarkers Of Inflammation And Mineral Metabolism

Background: The blood pressure-lowering effects of the Dietary Approaches to Stop Hypertension (DASH) dietary pattern and reduced sodium intake are well-established. The effects on other biomarkers related to vascular health are of interest and may assist in explaining cardiovascular benefits of the DASH diet. Objective: We hypothesized that a low-sodium DASH diet improves biomarkers of inflammation [i.e. reduces C-reactive protein (CRP) and soluble urokinase plasminogen activator receptor (suPAR)] and mineral metabolism [phosphorus and fibroblast growth factor-23 (FGF23)]. Methods: We conducted a post hoc analysis of the DASH-Sodium trial using stored frozen serum samples. This controlled feeding study randomized 412 adults to consume either a DASH diet or control diet representative of a typical American diet. Within each arm, participants received three sodium levels (low, intermediate, high) in random sequence, each for 30 days. To maximize contrast, samples collected at the end of the low-sodium DASH (n=198) and high-sodium control (n=194) diets were compared. Between-diet differences in biomarker concentrations were assessed by t-test or Wilcoxon rank sum test for normally distributed and skewed variables, respectively. Results: CRP concentrations did not differ between groups ( P =0.19), but suPAR was higher after the low-sodium DASH diet than the high-sodium control (median, IQR: 2473, 2127-2887 pg/mL vs. 2281, 1929-2679 pg/mL; P =0.003). FGF23 was also higher after the DASH diet (35.9, 26.9-44.8 pg/mL vs. 30.2, 23.5-37.5 pg/mL; P< 0.001). Serum phosphorus was higher after the DASH diet (mean±SEM: 3.5±0.04 mg/dL) versus the control (3.4±0.04 mg/dL; P =0.02). Conclusions: Contrary to our hypothesis, biomarkers of inflammation and mineral metabolism were increased or unchanged by a low-sodium DASH diet compared to a high-sodium control diet. Potential reasons (e.g. short duration of the trial, sodium-specific effects, bioavailable phosphorus-rich dairy intake) require further investigation.

Yield and economics of blackgram crop effected by green manures and phosphorus levels in riceblackgram cropping sequence

A field experiments was conducted during 2015 and 2016 to study the effect of green manures and phosphorus levels in blackgram crop at Agricultural College Farm, Bapatla. The experiment was conducted in split- split plot design on sandy clay loam soil with three main treatments three subtreatments to Kharif rice and three sub-sub treatments to Rabi crop. The treatments consisted of Dhaincha green manure crop, sunnhemp green manure crop and without green manure as main plot treatments and three phosphorus levels to rice crop comprising of 45 kg P2O5 ha-1, 60 kg P2O5 ha-1 and 75 kg P2O5 ha-1 as sub- plot treatments and are replicated thrice. The Rabi experiment was laid out on the same site in a split-split plot design without disturbing the soil for succeeding blackgram crop and each of the Kharif plot was divided into three sub-sub plots to receive three levels of phosphorus (No P, 50% RDP and 100% RDP) to each plot. Yield and economics of blackgram which received Dhaincha green manure incorporation with 75 kg P2O5 ha-1 to Kharif rice crop and 100% RDP to Rabi blackgram was recorded significantly higher and it was on a par with sunnhemp green manure incorporation with 75 kg P2O5 ha-1 to Kharif rice crop and 100% RDP to Rabi blackgram.

Application of convolutional neural network to acquisition of clear images for objects with large vertical size in stereo light microscope vision system.

For an object with large vertical size that exceeds the certain depth of a stereo light microscope (SLM), its image will be blurred. To obtain clear images, we proposed an image fusion method based on the convolutional neural network (CNN) for the microscopic image sequence. The CNN was designed to discriminate clear and blurred pixels in the source images according to the neighborhood information. To train the CNN, a training set that contained correctly labeled clear and blurred images was created from an open-access database. The image sequence to be fused was aligned at first. The trained CNN was then used to measure the activity level of each pixel in the aligned source images. The fused image was obtained by taking the pixels with the highest activity levels in the source image sequence. The performance was evaluated using five microscopic image sequences. Compared with other two fusion methods, the proposed method obtained better performance in terms of both visual quality and objective assessment. It is suitable for fusion of the SLM image sequence.

Maternal exposure to di-n-butyl phthalate induces alterations of c-Myc gene, some apoptotic and growth related genes in pups' testes.

The aim of this study was to investigate the effects of maternal exposure to di-( n-butyl) phthalate (DBP) on testicular development and function in pre-pubertal and post-pubertal male rat offspring. Fourteen pregnant female rats were equally divided into two groups: a control group and a DBP-treated group. During gestation day (GD) 12 to postnatal day (PND) 14, the control group was administered 1 ml/day corn oil, and the DBP-treated group was administered DBP 500 mg/kg/day by oral gavage. On PND 25 (pre-puberty) and PND 60 (post-puberty), blood for serum and the testes were collected from five male offspring of each group. To determine the relationship between the methylation state of the c-Myc promoter and the expression of the c-Myc gene, some apoptotic-related genes, such as p53 and Bax, the anti-apoptotic Bcl-2 gene, and some growth arrest-related genes, such as BRD7 and GAS1, were examined. Compared with the control ( p < 0.05), at pre-puberty, DBP induces c-Myc hyper-methylation with significant downregulation for c-Myc, p53, Bax genes, and significant upregulation for Bcl-2, BRD7, and GAS1, while at post puberty, the methylation state and expression of c-Myc and apoptosis-related genes returned to control levels in the same sequence with the fold change in the expression of BRD7 and GAS1 genes. These findings suggest that DBP induced a transient pre-pubertal increase in c-Myc promoter methylation that may be associated with disruption of both apoptotic and growth mechanisms in the testes.

Intelligent Offload Detection for Achieving Approximately Optimal Load Balancing

Load balancing is one of the critical issues, which dominates system performance in a storage cluster. To overcome load imbalance, many algorithms have to maintain real-time load conditions that often lead to high-communication overheads. Furthermore, they may require many replicas that significantly decrease storage utilization. In this paper, we present a novel algorithm called intelligent offload detection (IOD) that not only achieves approximately optimal load balancing but also contributes to improve communication overheads and storage utilization. Once non-hotspot data become hotspot data, IOD automatically establishes new partial replicas and replicates them to nodes with minimum load levels in sequence. Next, the arriving requests may be divided into a different number of sub-requests based on the load levels of related nodes. The IOD algorithm works with a partial replica policy so that it is effective to overcome skewed data access originated from hotspot data. Moreover, this policy enhances storage utilization. By classifying the loads into corresponding load levels, IOD is unnecessary for frequent load updates that decrease communication overheads. Simulation results demonstrate that the load balancing in IOD outperforms self-adaptive replication management (SARM) and approaches to optimal load balancing (OLB) under various network conditions. Besides, the amount of required replicas in IOD is relatively smaller than that in SARM and OLB.

Diverse sauropod-theropod-dominated track assemblage from the Lower Cretaceous Dasheng Group of Eastern China: Testing the use of drones in footprint documentation

The use of drones in the exploration and documentation of track surfaces in steep terrain, otherwise only accessible by time intensive climbing activity, is tested. Location is the Nanquan site, one of many now known footprint localities from the Lower Cretaceous Dasheng Group that has been recently exposed by local industrial excavation. It reveals an ichnofauna of sauropod, theropod, and ornithopod tracks and trackways occurring at multiple stratigraphic levels (at least 10) in a thin sequence of fine grained purple mudstones with thin sandstone units that are steeply inclined by >45°. It was therefore necessary and most efficient to map the track-bearing surfaces using drone photography. The majority of track-bearing levels reveal sauropod tracks (cf. Brontopodus, cf. Parabrontopodus), which on some surfaces are very abundant. Large theropod tracks (cf. Grallator) and ornithopod tracks (Caririchnium) also occur, but only on single horizons. The ichnofauna is evidence of repeated activity by large dinosaurs in a fluvio-lacustrine floodplain setting susceptible to periodic desiccation. The Naquan site forms part of an extensive Dasheng Group outcrop belt with multiple tracks sites, most of these containing multiple track-bearing levels. As a result of the investigation, drone techniques can be recommended as an additional tool for quick documentation, in order to get a general overview and map of the track surface. Details are relatively distinct on the achieved photographs, however, a precise study still needs direct examination and documentation by classical outline drawings or photogrammetry.

Production potential of maize as influenced by crop residue incorporation and nitrogen levels in legumecereal sequence

Production potential of maize as influenced by crop residue incorporation and nitrogen levels in legumecereal sequence

Ground-state Landégfactors for selected ions along the boron isoelectronic sequence

Land\'e $g$ factors for the fine-structure $1{s}^{2}2{s}^{2}2p\phantom{\rule{0.16em}{0ex}}^{2}P_{1/2}$ and $^{2}P_{3/2}$ levels in the boron isoelectronic sequence for selected $Z$ values have been calculated using the multiconfiguration Dirac-Fock method with both quantum-electrodynamic and electronic correlation corrections included. All-order Breit and vacuum polarization corrections were included in the calculation, with a fully optimized active set wave function. The results are compared with the available theoretical data, showing a very good agreement.

An Integrated Work Flow for a Comprehensive Evaluation of Thin, Silty Hydrocarbon-Reservoir Sequences

Summary A robust work flow is established to identify low-resistivity pay (LRP) in thinly laminated sands with silty and/or shaly layers. The work flow integrates data from gas-while-drilling, conventional logging, and nuclear-magnetic-resonance (NMR) logging for picking intervals for further examination with a wireline formation tester (WFT). A mini-drill-stem test (DST) is performed by means of a WFT equipped with either a single probe (SP) or a dual packer (DP) to determine the fluid type and productivity of each individual level. Two field examples are presented to compare well performance predicted by the microscale mini-DSTs with macroscale production tests. In both cases, the traditional DST is eliminated from the drilling/completion program. The final verification consists of comparing contributions of individual levels derived from the mini-DSTs with production logs. In the first case, mini-DSTs are able to provide the fluid type and individual-level transmissibility (kh/μ) for eight out of 13 distinct levels. A cost-effective approach of running mini-DSTs by means of a WFT equipped with a single probe is demonstrated to investigate multiple levels in the thin-hydrocarbon reservoir sequence. Guidelines are provided as to when a WFT with a DP is to be deployed to perform a mini-DST in a laminated formation. In the second case, the same work flow was applied to derive the fluid type and transmissibility for two wells consisting of more than 30 distinct levels in the same field. After integrating mini-DST results from the two wells 750 m apart, a framework is constructed to establish both vertical and lateral heterogeneities of thinly laminated reservoirs. The integration helps visualize the multiple-layer reservoir. Our examples confirm that mini-DSTs effectively define individual-layer producibilities in multiple-layered reservoirs. The benefits are illustrated through case histories that demonstrate our ability to manage expectations of well performance in thin hydrocarbon-reservoir sequences.

Middle cerebral artery peak systolic velocity to predict fetal hemoglobin levels in twin anemia-polycythemia sequence.

To evaluate the diagnostic accuracy of middle cerebral artery peak systolic velocity (MCA-PSV) Doppler measurements in prediction of hemoglobin levels in twin anemia-polycythemia sequence (TAPS). This study involved a consecutive cohort comprising monochorionic twin pregnancies complicated by TAPS managed at three European fetal medicine centers between 2005 and 2013. The accuracy of MCA-PSV, measured immediately prior to fetal hemoglobin (Hb) measurement by fetal or cord blood sampling, for prediction of anemia and polycythemia was assessed using 2 × 2 tables. A total of 116 measurements (74 recorded in donors and 42 in recipients) from 43 twin pregnancies complicated by TAPS were available for analysis. MCA-PSV multiples of the median (MoM) values correlated well with Hb levels (r = - 0.86; P < 0.001). The sensitivity of MCA-PSV ≥ 1.5 MoM to predict severe anemia (Hb deficit > 5 SD below the mean) in TAPS donors was 94% (95% CI, 85-98%); specificity was 74% (95% CI, 62-83%); positive and negative predictive values were 76% (95% CI, 65-85%) and 94% (95% CI, 83-98%), respectively. The sensitivity of MCA-PSV ≤ 1.0 MoM to predict polycythemia (Hb level > 5 SD above the mean) in TAPS recipients was 97% (95% CI, 87-99%); specificity was 96% (95% CI, 89-99%); positive and negative predictive values were 93% (95% CI, 81-97%) and 99% (95% CI, 93-100%), respectively. MCA-PSV measurement has high diagnostic accuracy for predicting abnormal Hb levels in fetuses with TAPS.

V2 of tomato yellow leaf curl virus can suppress methylation-mediated transcriptional gene silencing in plants

Tomato yellow leaf curl virus (TYLCV) is a DNA virus belonging to the genus Begomovirus. TYLCV replicates using double-stranded DNA intermediates that can become the target of plant transcriptional gene silencing (TGS). Here, we show that the V2 protein of TYLCV can suppress TGS of a transcriptionally silenced green fluorescent protein (GFP) transgene in Nicotiana benthamiana line 16-TGS. Through bisulfite sequencing and chop-PCR, we demonstrated that the TYLCV V2 can reverse GFP transgene silencing by reducing the methylation levels in the 35S promoter sequence. Both AtSN1 and MEA-ISR loci in Arabidopsis thaliana were previously reported to be strongly methylated, and we show that the methylation status of both loci was significantly reduced in TYLCV V2 transgenic Arabidopsis plants. We conclude that TYLCV can efficiently suppress TGS when it infects plants, and its V2 protein is responsible for the TGS suppression activity.

Implementing ICT Techniques in Teaching for the Effective Implementation of the New Nine Years UBE Curriculum in Anambra State

Implementing ICT Techniques in Teaching for effective implementation of the new nine years UBE curriculum is the objective of this research study. The study investigated the effective implementation of ICT in the new nine years UBE curriculum. The survey was based on four research questions. A sample total of 3048 science and non-science teachers consisting of 551 science teachers from private primary and 823 science teachers from public junior secondary schools, and 731 non-science teachers from from private primary and 943 non-science teachers from government owned junior secondary school from the six different educational zones in Anambra State. A questionnaire titled “implementing ICT Techniques in Teaching for Effective Implementation of the New UBE Curriculum” (IICTEINUBEC) was used for data collection. Data was analyzed using mean ratings. The Findings include that the schools did not have ICT course outlines specifying the progressive topics to be learnt by primary and Secondary school students, science based subjects which require the use of ICT for its effective teaching / learning are not being used. It was recommended that teachers should not teach the use of ICT in education independently but portraying its scientific nature correlating it with other conventional science subjects taught in schools and that ICT based education courses should be structured into the school curriculum so that it can be taught at different levels in logical and procedural sequence.

Evaluation of serum percent trisialotransferrin as potential predictive biomarker of hepatocellular dedifferentiation in chronic liver disease

Background and aim Chronic hepatitis induced liver fibrogenesis is characterized by epithelial-to-mesenchymal transition of liver parenchymal cells (hepatocytes) to fibroblast (-like cells), i.e. increasing hepatocellular dedifferentiation, ultimatively leading to the development of hepatocellular carcinoma (HCC). Up to now the spectrum of valid serum biomarkers for this process of hepatocellular dedifferentiation is very limited. We therefore investigated the dynamics of alterations in the serum transferrin isoform pattern in the pathogenetic sequence from liver fibrosis to hepatocellular carcinoma, to evaluate the suitability of one of the isoforms as potential biomarker for hepatocellular dedifferentiation in chronic liver disease. Results Our data on 252 patients with hepatitis C virus (HCV) induced fibrogenic liver disease and on 43 patients with HCV induced HCC demonstrate a dynamic alteration of serum % trisialotransferrin levels in the pathogenetic sequence from early stage hepatic fibrosis to fully developed hepatocellular carcinoma, whereas serum % di- and pentasialotransferrin values seem not to be affected. We show that patients with early stage fibrosis (METAVIR stage F1) and weak fibrogenic activitiy (METAVIR grade A1) display significantly lower values of serum % trisialotransferrin compared to healthy controls, and that serum % trisialotransferrin values increased steadily parallel to an increase of fibrotic stage and grade, respectively, while finally exceeding normal values in those patients with hepatocellular carcinoma. Conclusion These findings propose a possible diagnostic value of serum % trisialotransferrin concentrations in the pathogenesis of hepatocellular dedifferentiation and the use of this parameter as possible predictive tumor marker in patients with chronic liver disease. Monitoring the pattern of transferrin bound sialic acid residues may thus be a helpful tool in assessing the risk of malignant degeneration in patients with chronic fibrogenic liver disease.

Positron emission tomography and target-controlled infusion for precise modulation of brain drug concentration

There are several instances when it is desirable to control brain concentration of pharmaceuticals, e.g., to modulate the concentration of anesthetic agents to different desired levels fitting to different needs during the course of surgery. This has so far only been possible using indirect estimates of drug concentration such as assuming constant relation between tissue and blood including extrapolations from animals. A system for controlling target tissue concentration (UIPump) was used to regulate whole-brain concentrations of a central benzodiazepine receptor antagonist at therapeutic levels with input from brain kinetics as determined with PET. The system was tested by using pharmacological doses of flumazenil mixed with tracer amounts of [11C]flumazenil. Flumazenil was used as a model compound for anesthesia. An infusion scheme to produce three different steady-state levels in sequence was designed based on kinetic curves obtained after bolus injection. The subjects (Sprague-Dawley rats, n=6) were monitored in a microPET scanner during the whole experiment to verify resulting brain kinetic curves. A steady-state brain concentration was rapidly achieved corresponding to a whole-brain concentration of 118+/-6 ng/ml. As the infusion rate decreased to lower the exposure by a factor of 2, the brain concentration decreased to 56+/-4 ng/ml. A third increased steady-state level of anesthesia corresponding to a whole-brain concentration of 107+/-7 ng/ml was rapidly achieved. The experimental setup with computerized pump infusion and PET supervision enables accurate setting of target tissue drug concentration.

Management of High-Throughput DNA Sequencing Projects: Alpheus

High-throughput DNA sequencing has enabled systems biology to begin to address areas in health, agricultural and basic biological research. Concomitant with the opportunities is an absolute necessity to manage significant volumes of high-dimensional and inter-related data and analysis. Alpheus is an analysis pipeline, database and visualization software for use with massively parallel DNA sequencing technologies that feature multi-gigabase throughput characterized by relatively short reads, such as Illumina-Solexa (sequencing-by-synthesis), Roche-454 (pyrosequencing) and Applied Biosystem's SOLiD (sequencing-by-ligation). Alpheus enables alignment to reference sequence(s), detection of variants and enumeration of sequence abundance, including expression levels in transcriptome sequence. Alpheus is able to detect several types of variants, including non-synonymous and synonymous single nucleotide polymorphisms (SNPs), insertions/deletions (indels), premature stop codons, and splice isoforms. Variant detection is aided by the ability to filter variant calls based on consistency, expected allele frequency, sequence quality, coverage, and variant type in order to minimize false positives while maximizing the identification of true positives. Alpheus also enables comparisons of genes with variants between cases and controls or bulk segregant pools. Sequence-based differential expression comparisons can be developed, with data export to SAS JMP Genomics for statistical analysis.