This paper presents heuristic equations for estimating odor emissions from open-roof rectangular tanks as a function of the tank orientation, wind direction, wind speed and distance of the emitting surface from the tank top. These types of equations are important because they may help to improve emission calculations to avoid overestimations, which are damaging to the plant owner, and underestimations, which are negative for the population around the plant. Odor emissions were determined for four tanks with the same area, different shape factors and two different orientations and then used as inputs for a dispersion model in order to calculate separation distances and evaluate their differences. The results show that different separation distances were obtained depending on the tank orientation, shape factor and level of filling. Future field applications to verify and improve the proposed equations are desirable. If the effect of the tank orientation on odor emission is proven, the design of future industrial plants containing open-roof rectangular tanks should consider the results of detailed wind data analysis.